<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation G333E
Rx RTI-naive
IncludeMixtures No
References 22
Patients 41
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Maljkovic (2003)MI_Pat4999SE18397AY165223NoneNone  V35T, E36A, T39E, S48T, K122E, S162Y, K173A, D177E, I178L, G196E, T200A, E204K, Q207E, R211M, P243T, V245Q, S251N, A272P, Q278R, T286A, E291D, V292I, I293V, G333E, Q334H, G335DC
Carrion (2004)ARG4006ARG4006AY563170NoneNone  V35T, T39E, S48T, K122E, A158S, K173A, D177E, T200A, E204K, Q207E, R211K, F214L, V245Q, A272P, E291D, V292I, I293V, E297A, G333E, R356K, G359T, K366R, T377Q, V381I, K390R, A400S, E404D, V435T, L452M, V466I, S468A, H483Q, S519N, K527Q, A534S, A554S, K558RC
Bussmann (2005)01BW386S01BW386SAY829276NoneNone  V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, I178M, T200A, Q207N, V245H, D250E, S251N, A272P, E291D, V292I, G333E, Q334HC
Weber (2005)F81301F81301AY677579NoneNone  V35T, E36A, T39E, S48T, K122E, D123S, I142V, A158S, K173A, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, S322A, I329IL, G333EC
Rousseau (2006)Pt16804PS284B1DQ164120NoneNone  V35T, T39K, S48T, V60I, K122E, D123G, I142V, S162A, K173A, D177G, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P313T, V317A, G333E, Q334N, R356K, M357K, G359T, I375V, T377L, K390R, A400R, E404D, V435A, G436E, V467I, S468T, L469I, D471E, H483Q, L491S, E492K, S519N, K527N, A534S, A554K, K558RC
Brumme (2007)1332PRRT_1332EF368642NoneNone  V21I, V35T, E36A, T39E, S48T, V60I, K122KE, K173T, D177E, T200A, I202IV, Q207R, R211K, V245HQ, K277R, E291D, V292I, I293V, G333E, Q334H, R356K, G359AT, T377M, K390R, A400TC
Vidal (2007)U270202BU.U2702AM260248NoneNone  K32R, V35T, E36A, T39E, S48T, K122E, A158S, K173T, D177E, T200A, Q207K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329L, G333E, R356K, G359T, T377L, K390R, E404DC
 U070202BU.U0702AM260287NoneNone  K32E, V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135R, A158S, K173A, D177E, T200A, Q207N, D218X, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I326V, G333E, R356K, M357L, G359T, K366R, T377M, K390R, A400T, E404DC
Matthews (2008)PS164PS164FJ199727NoneNone  D177E, T200A, Q207G, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, G333E, Q334Y, R356K, G359T, T377L, K385R, T386I, K390R, T397A, E399G, A400I, E404D, V435I, L452M, R461K, V466I, S468T, T470S, D471E, H483Q, E492G, S519N, K530R, A534SC
 PS284PS284FJ199775NoneNone  V35T, T39K, S48T, V60I, K122E, D123G, I142V, S162A, K173A, D177G, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P313T, V317A, G333E, Q334N, R356K, M357K, G359T, I375V, T377L, K390R, A400R, E404D, V435A, G436E, V467I, S468T, L469I, D471E, H483Q, L491S, E492K, S519N, K527N, A534S, A554K, K558RC
 SK038SK038FJ199864NoneNone  V8I, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177G, V179I, T200A, I202V, Q207A, V245Q, D250E, S251N, A272S, T286A, E291D, V292I, I293V, G333E, Q334C, T338S, R356K, G359T, T377L, K390R, A400R, E404D, E413D, V435A, L469I, D471E, H483QC
Nyombi (2008)TMS348TMS348EU251881NoneNone  V8I, V35T, E36A, T39E, S48T, K122E, A158S, K173A, Q174H, D177E, T200A, Q207A, R211K, P243T, V245Q, E248D, A272S, K277R, T286A, E291D, V292I, I293V, E297K, G333E, F346Y, R356K, M357T, G359AC
Huang (2009)Blm_x0555Blm_x0555KT737105NoneNone  V35T, E36A, T39E, S48T, I63V, K122E, D123N, I132M, S162C, E169D, K173A, Q174K, D177E, I178L, T200A, Q207K, R211Q, V245Q, A272P, K277R, V292I, I293V, K311R, I326V, G333E, Q334D, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, L452I, K454R, V466I, D471E, H483Q, L491S, E492K, L517I, S519N, A534SC
 Blm_x0167Blm_x0167KT737027NoneNone  T27S, V35T, T39E, S48T, K122E, D123G, F124L, A158S, S162A, F171L, R172G, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K281R, R284K, E291D, V292I, I293V, P294T, D324E, G333E, Q334H, G359TC
Vercauteren (2009)pt10526936846529GQ399972NoneNone  T39E, S48T, K103KR, K122E, D123N, K173A, I178M, T200A, Q207E, V245Q, E248ED, D250E, S251SDGN, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, K311R, G333E, Q334HC
Chaturbhuj (2010)1-0151-015FJ878944NoneNone  V35T, T39TAEK, S48T, V60VI, K122E, D123S, K173A, D177E, I178M, T200A, Q207N, R211K, V245Q, A272P, E291D, I293V, G333EC
Tymchuck (2010)MW23MW23HM744732NoneNone  V35T, T39E, S48T, K122E, K173A, Q174R, D177E, G196E, T200A, Q207E, R211K, V245Q, E248V, K277R, T286A, I293V, G333E, Q334HC
Hamers (2011)302393CP076302393HM120102NoneNone V179VDV21I, V35T, T39E, K43R, S48T, W88C, K102Q, V118I, K122E, E138A, T139A, S162C, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, T286TA, E291D, V292I, P313Q, I329IV, G333E, Q334NC
 303959CP076303959HM120146NoneNone  V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, T200A, E204K, Q207D, R211K, P243S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, G333E, Q334LC
Kousiappa (2011)CY205CY205JF683757NoneNone  V35T, E36A, T39E, S48T, E53ED, K104R, K122E, S162Y, K173A, D177E, I178M, I195L, G196E, T200A, E204K, Q207E, P243T, V245Q, A272P, K275R, Q278H, K281R, T286A, E291D, V292I, I293V, G333E, Q334H, G335D, R356K, M357R, G359T, T377R, T386I, K390R, E399D, A400S, E404D, L422I, V435A, S468T, D471E, H483Q, L491S, E492K, S519N, K527N, E529D, A534S, V548A, A554SC
Manak (2012)25_LH0225_LH02JN687649NoneNone  E6K, V35T, E36A, T39E, S48T, V60I, K102R, K103R, K122E, I142K, T165V, K173A, Q174K, D177E, G196E, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, G333E, G335S, R356K, M357I, G359T, T377M, K390R, A400T, E404D, V435A, G436E, L452I, V467I, S468T, L469I, D471E, H483Q, L491S, S519N, K530R, A534S, A554S, K558RC
Bila (2013)MZ10-159HIV-1KF927264NoneNone  T27S, K32N, V35K, T39D, S48T, V60VI, D123E, I135R, K173T, T200A, I202IV, E204K, Q207E, R211K, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, H315HY, S322A, G333E, Q334HC
 MZ10-143_XAHIV-1KF927250NoneNone  V35T, T39K, E40D, S48T, K104R, K122E, D123NS, I135V, K173AT, D177E, T200K, Q207A, R211K, P243T, V245Q, A272AS, K277R, T286A, E291D, V292I, I293V, G333E, Q334HC
 MZ10-188HIV-1KF927289NoneNone  K13KR, V35K, T39D, S48T, T58TP, K122E, D123N, S162AT, K166R, K173A, D177E, T200A, E204K, Q207E, V245Q, A272P, K275R, K277R, Q278HN, T286A, E291D, V292I, I329L, G333E, Q334H, G335SC
Nzeyimana (2013)201_1668201_1668HG780701NoneNone  V35T, E36AV, T39E, S48T, K101KR, K122E, D123S, A158S, K173A, D177E, T200A, Q207EK, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297T, K311R, I329L, G333E, R356K, G359T, T377L, K390R, E404DC
 102_1134102_1134HG780791NoneNone  V35T, T39L, V60I, K102Q, I142V, D177E, I178M, V179I, S191SF, T200R, E204D, Q207E, R211KT, V245Q, T286A, E291D, V292I, I293V, K311R, D324E, G333E, Q334QP, M357K, G359S, K366R, T369V, A371V, I375V, A376T, T377M, K390R, A400T, E404D, E432DC
 102_1271102_1271HG780839NoneNone  V35T, E36A, T39E, S48T, K122E, D123N, A158S, K173A, D177E, T200A, Q207E, R211K, V245Q, L260LV, K281R, T286A, E291D, V292I, I293V, G333E, Q334H, G335S, R356K, M357V, T377L, V381I, K390R, E404DC
 201_1811201_1811HG780684NoneNone  V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, Q207E, R211KT, V245Q, D250E, A272P, E291D, V292I, I293V, P313T, G333E, R356K, G359T, V365I, T377Q, S379C, K385R, K390R, A400T, E404DC
 201_4404201_4404HG780633NoneNone  K32R, V35T, T39E, S48T, K122E, D123S, T139S, A158S, S162C, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245E, A272P, K277R, T286A, E291D, V292I, I293V, G333E, R356K, G359T, Q367L, T377Q, K390R, E404D, I434MC
 102_1073102_1073HG780803NoneNone  V35T, E36A, T39E, S48T, K122E, D123S, A158S, T165I, K173A, D177E, T200A, E204D, V245Q, A272P, K277R, T286A, V292I, I293V, I326V, G333E, R356K, G359A, T377M, K390R, A400AT, E404DC
 102_1003102_1003HG780852NoneNone  V35T, T39N, S48T, V60I, D121H, K122E, A158AS, K173S, Q174K, D177E, T200A, Q207E, R211M, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G333E, Q334H, E344D, R356K, M357MI, G359T, K366R, T377L, K390R, E404DC
Li (2015)217217KP235105NoneNone  V35T, T39D, V60I, K102R, D121Y, K122E, I178M, T200A, V245Q, A272P, E291D, V292I, I293V, P313T, G333E, R356K, G359T, A376AV, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554SC
Novitsky (2015)mpp_478mpp_478KR861236NoneNone  V35T, T39Q, S48T, V60I, K122E, D123S, K166R, K173T, D177E, T200A, E204D, Q207T, R211K, P243T, V245Q, E248T, A272S, E291D, V292I, I293V, G333E, Q334H, F346H, G359S, K366R, T377M, K390R, E399N, A400T, E404D, V435G, E449D, L452K, V467I, T470N, D471E, H483Q, L491P, L517I, S519N, Q524E, K530R, V531I, A534S, A554NC
 bcpp_180bcpp_180KR860676NoneNone  P4S, V35T, T39E, S48T, D121H, K122E, A158S, S162C, E169Q, K173E, Q174K, D177E, T200A, Q207E, R211T, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, G333E, Q334N, R356K, G359T, T377V, S379A, K385R, K390R, A400T, E404D, V435A, K454R, H483Q, L484I, L491P, Q507H, A508G, S519N, Q524K, K527Q, V531I, A534S, A554KC
 mpp_259mpp_259KR861038NoneNone  V35T, T39E, S48T, K64R, K122E, K173T, T200A, E204D, Q207A, R211K, V245K, P247A, A272P, T286A, E291D, V292I, I293V, I329L, G333E, Q334N, G335D, R356K, M357R, G359S, T377M, K390R, A400T, E404D, N447S, L452Q, V458I, D460N, V466I, V467I, S468N, D471E, H483Q, L491P, L517I, S519N, K527R, K530R, A534S, V548I, A554TC
 mpp_009mpp_009KR860801NoneNone  V35T, E36A, T39E, S48T, A158S, K166R, K173A, D177E, T200A, Q207G, V245M, A272P, K277R, T286A, E291D, V292I, I293V, K323Q, D324E, I329L, G333E, Q334N, G335N, R356K, G359T, T377M, K388R, K390R, A400I, E404D, V435A, L452G, V466I, D471E, T477A, I482V, H483Q, L491S, A502V, S515A, L517I, S519N, K530R, A534S, A554NC
 mpp_115mpp_115KR860898NoneNone  V8I, V35T, T39K, S48T, K122E, D123N, K173A, N175H, D177E, T200A, K201T, E204K, Q207D, P243Q, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E, G333E, G335S, R356K, G359T, T377M, S379C, K390R, A400T, T403S, E404D, E449D, L452I, R461K, L469I, D471E, H483Q, L491P, S519N, K530R, A534S, A554SC
Billings (2016)CO3969V6CO3969V6KX907391NoneNone  E6A, V35T, E36A, T39E, S48T, K122E, D123S, K166R, K173T, D177E, T200A, Q207D, R211K, V245I, D250E, A272S, K277R, K281R, T286A, E291D, V292I, I293V, G333E, Q334Y, R356K, G359T, A360T, A376S, T377L, K385R, T386V, K390R, E399D, A400T, E404D, V435G, F440Y, V466I, D471E, T477A, H483Q, L491P, E492D, S519N, L525M, K527Q, K530R, A534S, A554SC
 CO0844V2CO0844V2KX907354NoneNone  E6K, V35T, E36A, T39E, S48T, K122E, I135M, K166R, K173A, D177E, T200A, Q207E, R211K, V245K, D250E, A272P, K275R, K277G, T286A, E291D, I293V, G333E, M357K, G359S, T369A, A371V, I375V, A376V, T377M, T386A, K390R, A400T, T403A, E404D, E432D, V435A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S, V559IC
Steegen (2016)GFGPA053GFGPA053KT893236NoneNone  V35T, T39E, S48T, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, I202V, Q207K, R211RKQ, V245Q, A272P, K277R, T286A, K287KE, E291D, V292I, I293V, E297V, V317A, G333E, Q334N, G335S, R356K, G359T, K366KR, T377M, T386I, K390R, E399ED, A400IT, E404D, L429M, V435AC
 GFMPA008GFMPA008KT893089NoneNone  V35T, E36A, T39E, S48T, K122AE, T165I, K173A, Q174K, D177E, I178V, T200A, E203D, Q207D, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, E297K, D324E, I329L, G333E, Q334D, G335D, R356K, M357R, G359T, K366R, I375V, T377L, T386I, K390R, E399D, A400L, T403R, E404DC