<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation T215F
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 8
Patients 23
Isolates 23
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)SA75_DR16SA75_DR16AY901709ABC, AZT, 3TCNoneM41L, D67N, T69D, M184V, L210W, T215FA98GV35T, T39E, E44D, S48T, E53D, V111I, V118VI, D121DG, K122E, D123S, E138EA, K173A, Q174K, D177E, G196E, T200A, E203V, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
 TK3032TK3032 AZT, 3TC, D4TNoneM41L, M184V, T215FV179DV8I, K20R, V35T, E36A, T39E, S48T, V118I, K122E, D123N, I135T, S162T, E169Q, K173T, Q174K, T200A, Q207E, R211K, F214L, P243T, V245Q, E248D, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, D324E, I329LC
 PL4205691776 3TC, D4T, ABC, TDFNoneM41L, L210LW, T215F K20R, V35IT, T39E, S48T, K122E, D123S, I135T, T139TM, K173E, Q174QK, D177E, E194ED, G196K, T200A, I202V, Q207E, R211K, V241I, V245KR, E248D, D250E, A272P, K277R, E291D, I293V, I329VC
Pillay (2008)DR1602ZA.DR16AY589877ABC, AZT, 3TCNoneM41L, D67N, T69D, M184V, L210W, T215FA98GV35T, T39E, E44D, S48T, E53D, V111I, V118VI, D121DG, K122E, D123S, E138EA, K173A, Q174K, D177E, G196E, T200A, E203V, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293VC
Rosen-Zvi (2008)7106p71-2 AZT, 3TC, ABC, TDFNoneM41ML, D67DN, M184V, T215FK103KNV35T, K122E, D123S, I142V, K173A, Q174K, D177E, T200A, R211K, D218DE, L228LR, E248D, A272P, T286A, E291D, V292I, I329LC
Deshpande (2009)Pat24814artFJ530693AZT, 3TCNoneD67N, K70R, M184V, T215F, K219EA98AGV35T, T39E, S48T, V60I, T69N, V118I, D121H, K122E, I135T, K173AT, D177E, I178M, T200A, E204K, Q207E, F214L, E224D, V245QC
 Pat21316RTFJ530728AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219QA98G, K101EQ, G190AK20R, E28EK, V35T, T39D, E44D, S48T, V60I, T69N, D121H, K122E, F124FV, I135T, K173A, Q174R, I178M, T200A, Q207E, R211RK, V245Q, L246WC
 Pat044327FJ530897AZT, 3TCNoneM41ML, D67N, K70R, V75M, M184AV, T215F, K219EG190AL12I, V35T, T39N, V60I, T69TN, D121HY, K122E, I135M, S162SN, K173A, D177E, V179I, E203EV, Q207E, L228H, V245QC
 Pat043329FJ530898AZT, 3TCNoneM41L, D67N, K70R, V75M, M184V, T215F, K219EG190AV35T, T39N, V60I, D121H, K122E, I135M, K173T, D177E, V179I, Q207E, L228H, V245QC
Van Zyl (2013)327211.ZA.GT1915KC423704AZT, 3TC, DDINoneD67N, T69D, K70R, V75I, T215F, K219Q V35T, T39E, V60I, W88C, K122E, I132L, K173A, D177E, I178L, G196E, T200A, K201R, E203ED, E204K, Q207E, F214L, L228R, V245Q, E248DC
 46409.ZA.WC037KC424311AZT, DDINoneT215F V35I, E36EA, T39E, S48T, K122E, D123G, I135T, K173A, Q207N, L210LF, R211K, D218E, V245KC
 111808.ZA.EC010KC423322AZT, DDINoneM41L, D67N, K70R, V75M, L210W, T215F, K219QA98G, K101EE28K, K32I, V35T, T39E, V60I, K122E, D123DG, I135V, S162C, K173A, Q174K, D177E, I178L, G196GE, T200A, K201KR, E203A, Q207E, H208Y, R211K, L228H, V245QC
 59709.ZA.WC046KC424339AZT, DDINoneT215FA98G, K103NV35T, T39D, S48T, E53D, K122E, D123S, I135L, S162C, K173A, I178L, G196E, T200A, Q207E, R211K, L228Q, V245Q, E248DC
 26012.ZA.NL010KC423765AZT, 3TCNoneD67N, K70R, M184V, T215F, K219EA98G, K101E, Y181CV35T, E36A, T39E, S48T, V60I, K122E, D123S, T139R, E169A, K173A, Q174E, T200A, E203K, Q207E, F214L, V245KC
 190411.ZA.GT1698KC423495AZT, DDINoneT215FA98G, K103NK20R, V35T, T39E, S48T, V60I, K102R, K122E, D123G, I135L, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245QC
 224810.ZA.GT1436KC423227AZT, DDINoneM41ML, D67N, K70R, T215F, K219QK101KEV35T, T39E, S48ST, V60VI, E89EG, K122E, D123N, I135IL, E138A, K173A, D177E, I178L, T200A, Q207D, R211K, V245Q, E248DC
 65211.ZA.WC150KC423489ABC, 3TC, AZTNoneM184V, T215FA98G, K238TK20R, V35T, T39E, S48T, K49R, S68SG, K122E, D123G, A158S, S162A, T165L, K173A, Q174QK, D177E, I178M, T200A, Q207E, V245QC
Steegen (2014)12ZAKS26112ZAKS261KJ176540TDF, D4T, 3TCNoneM41L, D67N, T69D, K70R, V75M, M184V, T215FK103N, V106MV35T, E36EA, T39AE, S48T, K49R, V60I, K122E, I135T, T139K, S162SN, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, W212M, F214L, K223E, P243S, V245K, K249Q, A272P, E291D, I293V, P313PS, V317VA, S322A, Q334N, G335D, A355S, R356K, R358K, G359N, A376S, T377L, K390R, E399D, A400I, T403A, E404DC
 12ZAKS29512ZAKS295KJ176574TDF, D4T, 3TCNoneM184V, T215FV179E, Y188LV8I, V35K, T39E, V60I, K102W, I135T, K173A, Q174K, D177E, T200A, Q207QE, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, M357K, R358K, G359S, E370D, T377M, K390R, K395R, E399D, A400T, E404D, E430RC
Chimukangara (2016)NC15NC15KU508560TDF, FTC, 3TCNoneD67N, T69D, K70R, M184V, T215F, K219EK103S, Y181C, G190AV35K, E36A, T39E, S48T, V60I, K102R, V118I, K122E, D123G, S162N, K173T, D177E, V179I, T200A, I202V, R206K, Q207E, R211K, F214L, L228HC
Neogi (2016)714313.ZA.EC707KT592854D4T, 3TCNoneD67N, K70R, M184V, L210LW, T215F, K219EY188LI2V, V8I, V35K, T39E, S48T, V60I, T69N, A98S, V118VI, D121H, K122E, K173T, Q174K, D177E, V179VI, T200E, E203K, Q207E, H208HY, D218E, V245QC
 67013.ZA.EC722KT592865D4T, 3TCNoneM41L, A62V, V75I, M184V, T215FV106M, G190A, F227LP4S, I31L, V35I, E36A, T39E, L109I, S162A, F171Y, K173A, Q174K, T200A, I202V, Q207A, R211K, V245QC
 711513.ZA.EC535KT592738AZT, 3TCNoneM41L, M184V, T215FY188LV35IT, E36*L, T39E, S48T, V60I, S68SG, L109I, K122E, D123G, K173A, Q174K, D177E, V179I, T200A, Q207E, R211K, D218E, K238R, V245QC