<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation F116Y
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Johnston (2003)TC-71TC-71 DDI, AZT, 3TCNoneA62V, K65R, F116Y, Q151M, M184V V8I, V35T, T39E, V60I, S68R, W88S, K101Q, K122E, D123S, I135T, E138A, K173T, Q174K, V179I, T200A, Q207E, R211K, F214L, V245Q, E248DC
Non-B Workgroup (2005)SA71_2504SA71_2504AY589838AZT, D4T, DDINoneV75I, F77L, F116Y, Q151M G15A, V35T, E36A, T39E, S48T, S68G, V111I, K122E, D123G, I135V, K173A, T200E, Q207A, R211K, V245Q, A272P, K275Q, Q278K, T286A, E291D, V292I, I293VC
 UK2069UK2069AY901392DDC, AZT, D4T, DDI, 3TCNoneF116Y, Q151M, M184VG190AK20R, V35T, E36A, T39E, N57Y, V111I, K122E, D123N, A158S, K173A, D177E, T200A, R211K, F214C, Q222QHC
Pillay (2008)DR43DR43AY589898AZT, 3TC, D4T, DDINoneF116Y, Q151M K32E, V35T, E36A, T39AE, S48T, K122E, D123G, I135K, I142IV, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, F214FL, V245Q, A272P, I274V, K275Q, K277R, T286A, E291D, V292I, I293VC
 DR59DR59AY589911D4T, DDINoneA62V, K65R, V75I, F77L, F116Y, Q151M T39E, S68G, A98S, K122A, S162SCNY, S163ST, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, Q278H, I293V, S322A, Q334XC
 DR68DR68AY589917AZT, 3TCNoneA62V, K65KR, V75I, F77L, F116Y, Q151M, M184V V35T, T39EK, E40EK, S48T, S68G, T69TI, K122E, D123S, S162C, K166KR, K173T, Q174K, I178IL, E194AT, G196E, T200A, I202IV, Q207E, F214L, V245Q, E248D, A272P, E291D, V292VI, I293V, E297KC
 DR10203ZA.DR102AY589937D4T, DDINoneA62AV, V75I, F77FL, F116Y, Q151M A33AV, V35T, T39E, S68SG, T69S, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q, S251N, A272P, K275Q, K277R, T286A, E291D, V292I, I293VC
Acharya (2014)DGP065DGP065KJ185235TDF, 3TCNoneF116Y, Q151M, M184VA98G, Y181C, G190AV35T, E36A, T39D, S48T, V60I, L109I, D121H, K122E, K173I, D177E, I178M, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 DGP025DGP025KJ185195TDF, 3TCNoneA62V, K70N, V75I, F77L, Y115F, F116Y, Q151M, M184VG190A, F227LV35T, E36A, T39D, S48T, K49R, V60I, D121Y, K122E, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K275Q, K277R, T286A, E291D, V292I, I293VC
Posada Cespedes (2017)313606.ZA.GT015KX539561AZT, 3TCNoneK65R, K70R, V75I, F77L, F116Y, Q151MK103N, V106MV21I, K32I, V35T, T39K, S48T, K64KQ, S68G, V118I, K122E, D123S, T139A, I142T, T165I, Q182H, G196E, T200A, Q207E, F214L, L228Q, A272P, Q278H, T286A, E291D, V292I, I293VC