<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation T69N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 47
Patients 177
Isolates 217
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ruiz (1996)JCS-C47C47BZ99336AZT, DDINoneD67G, K70R, K219Q I5N, T69N, R83K, V118I, F214L, V245KB
 JCS-C27C27BZ99320DDC, AZTNoneD67N, K70R, T215F, K219Q K64H, T69N, K122P, D177E, Q207EB
  C27W24Z99321DDC, AZT, 3TCNoneD67N, K70R, M184V, T215S, K219Q K64H, T69N, K122P, D177E, Q207E, L210G, P217Q, L228HB
 JCS-C7C7BZ99302DDC, AZTNoneD67N, K70R, T215F, K219Q T69N, K104N, R211SB
  C7W24Z99303DDC, AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q M16I, K43R, T69N, A98S, K104N, M164I, E194G, I202V, R211SB
Hammer (1997)ACTG320_14301430 AZTNoneK70R K20R, K64KR, T69N, A98S, I135V, S162C, T200TA, F214L, T286A, I293IV, E297Q, A360V, K390R, A400T, V435A, G436E, A446S, L452V, D460N, H483YB
 ACTG320_18571857 AZT, DDI, D4TNoneK70R, K219Q V60I, T69N, V118I, F214L, V245K, R284RK, I293V, R356RK, M357MT, R358RK, K390R, A400T, V435I, L452S, S468PB
 ACTG320_2424 AZT, DDINone  V35I, S68G, T69N, R83K, I135T, K166R, G196E, R211K, V276I, T286A, K366KR, D460N, R461KB
 ACTG320_25132513 AZT, DDI, DDCNoneD67N, K70R, T215F, K219Q K20R, V35IM, T69N, K104N, I135V, I178IM, I202IV, V245EK, A272P, K277R, K281R, E291D, I293IV, E297K, Q334C, R358RK, A360AT, A400T, V435IM, K451KR, D460N, R461RK, H483YB
 ACTG320_25712571 AZT, D4TNoneD67N, K70R, K219Q T39TA, V60I, T69N, K82KR, K103R, I135AT, G196E, F214L, K277R, V317A, G335S, G359S, I375V, A376S, S379C, K390R, V435A, G436EB
 ACTG320_27302730 AZT, DDI, DDC, D4TNoneD67N, K70R, K219Q V60I, K64KN, T69N, K103Q, I135T, S162C, L228H, I293V, E344D, A371AV, I375IV, T403M, S468P, L469LIB
 ACTG320_27972797 AZTNoneD67N, K70R, T215Y, K219Q K20R, T69N, V118I, I135T, E138A, K166KR, R211K, F214L, P243T, K277R, T286A, E291D, P294ST, E297K, Q334E, T369TA, A376T, K390R, A400T, T403A, L452LI, D460N, S468A, L469I, H483YB
 ACTG320_29492949 AZTNoneD67A, K70R, K219Q T69N, K103R, K104N, S162A, F214L, T286A, R356RK, A360V, A400I, E432D, V435E, V458I, D460NB
 ACTG320_31513151 AZT, 3TCNoneK70R T69N, R83K, D121DY, S162C, T200TA, V245K, S251I, T286A, A288G, Q334DE, R356RK, G359S, V372L, A376T, T386A, K390R, A400T, Y427YS, Q480E, I482XB
 ACTG320_361361 DDC, AZTNoneD67NT, K70R, T215F, K219E E6D, T39TP, T69N, K102Q, S162C, I202V, L210F, R211K, L228H, K277R, T286A, P294T, E297K, Y342F, M357I, R358K, A376V, K390R, A400T, T403TM, N447S, L452I, T470A, H483CB
 ACTG320_36683668 AZT, DDC, D4TNoneK70R K11KR, K20KR, T69N, R83K, A98S, I135V, S162A, Q197P, T200A, E203K, Q207E, R284K, T286A, K311KR, I329V, K366R, D460N, K476XB
 ACTG320_39653965 AZT, DDC, D4TNoneD67N, K70R, T215FS, K219Q K64H, T69N, I178L, D218DE, E291ED, S322A, R356RK, A360AV, A400T, S468PB
 ACTG320_618618 AZT, D4TNoneK70R, T215Y K20R, V60I, T69N, R83K, I135V, S162C, I178M, Q207E, R211K, A272P, K366R, Q373H, A400TB
Nijhuis (1997)PT-C0034C0034W46 3TCNoneM184V K20R, T69N, R211K, E248DB
  C0034W94 3TC, AZTNoneM41L, D67N, K70R, M184V, T215F, K219E K20R, T69N, I135T, R211K, E248DB
  C0034W142 3TC, AZTNoneM41L, D67T, K70R, M184V, T215F, K219E K20R, T69N, I135T, R211K, E248DB
Mulato (1998)GS94ptCGS94ptC AZT, DDINoneK70R T69N, R83K, I135T, S162C, T200A, Q207E, V245KB
  GS94ptC AZT, DDI, ADVNoneM41L, T215Y T69N, R83K, A98S, I135T, S162C, T200A, Q207E, V245KB
Orlandi (1998)PO-Pt14Orl14-W186AF056666AZTNoneD67N, K70R, K219Q E6D, V35T, T39A, I50V, V60I, T69N, D123E, I135T, T200I, F214LB
  Orl14-W202AF056667AZTNoneD67N, K70R, K219Q E6D, V35T, T39A, I50V, V60I, T69N, D123E, I135T, T200I, F214LB
 PO-Pt17Orl17-W224AF056670AZTNoneD67N, K70R, K219Q T39A, T69N, K103R, D123E, K166R, Q207A, R211K, F214LB
  Orl17-W228AF056671AZTNoneD67N, K70R, K219Q T39A, T69N, K103R, D123E, K166R, Q207A, R211K, F214LB
 PO-Pt24Orl24-W165AF056683AZTNoneK70R K20R, T69N, R83K, G196E, Q207EB
  Orl24-W182AF056684AZTNoneK70R K20R, T69N, R83K, G196E, Q207EB
Cabana (1999)Cab-cC0AF102336DDC, AZT, 3TCNoneD67N, K70R, T215F, K219Q K64H, T69N, K122P, D177E, Q207EB
  C17AF102337DDC, AZT, 3TC, D4TNoneD67N, K70R, M184V, T215F, K219QA98GK64H, T69N, D113N, K122P, I135V, D177E, Q207E, L228HB
 Cab-dD29AF102340DDC, AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q T69N, K104N, R172K, I202V, R211S, D218EB
 Cab-kK24AF102364DDC, AZT, D4T, 3TCNoneQ151M, M184V T69N, K122E, I135T, S163C, D177N, G196E, I202VB
Lawrence (1999)JL-Pt4JL-4-pre AZT, 3TCNoneD67N, K70R, K219Q K20R, T69N, V90I, K122KE, D123E, I135T, I178M, G196E, T215X, V245MB
  JL-4-post AZT, 3TCNoneD67N, K70R, M184V, K219Q V60I, T69N, D123E, I135T, G196E, V245MTB
Venturi (1999)GV-9Vent9W24AF169059AZT, DDINoneK70R, K219Q V60I, T69N, D123E, F214LB
 GV-11Vent11BAF169062AZTNoneD67N, K70R, T215S, K219Q G51A, T69N, V106I, D123E, I135IT, Y144Y*, F214LB
  Vent11W24AF169063AZT, DDINoneD67N, K70R, T215S, K219Q K43R, T69N, V106I, V118M, D123E, I135T, Y144*, F214LB
 GV-13Vent13BAF169066AZTNoneK70R, T215F, K219Q D67X, T69N, K104N, V118I, K122E, I135T, A158S, S162D, G196X, I202V, R211X, F214LB
 GV-32Vent32BAF169104AZTNoneK70R V35I, S48E, T69N, D123E, I135T, I142V, F214LB
  Vent32W24AF169105AZT, 3TCNoneK70R S48E, T69N, D123E, I135T, I142V, F214LB
Zolopa (1999)CA1127CA3164AF088114AZT, DDI, DDC, 3TC, D4TNoneD67N, K70R, M184V, T215F, K219Q K20R, T69N, K102R, K122P, I135V, D177E, V179I, G196E, F214FL, V245T, A272P, Q278HB
 CA1170CA2657AF088118AZT, DDI, 3TC, D4T, DDCNoneD67N, K70R, M184V, T215V, K219E T69N, I135T, T200A, Q207EB
 CA1173CA3099AF088082AZT, DDI, 3TC, D4TNoneD67N, K70R, M184V, K219Q T27S, I31V, K64H, T69N, K122E, I195L, D218E, L228H, V245M, E248V, K249Q, A288T, I293VB
Albrecht (2000)ACTG303_14411441RT_f1 AZT, DDI, 3TCNoneM41ML, D67N, K70R, M184V, T215FS, K219Q K20R, V35M, V60I, T69N, K104N, D123E, S162C, D177DE, I178L, Q207E, F214FL, D218DE, A272P, T286A, I293VB
 ACTG303_19261926RT_bl AZT, DDINoneD67N, K70R, T215F, K219Q V35I, S48T, V60I, K64H, T69N, Q207E, D218E, A272P, K277R, I293VB
 ACTG303_53885388RT_f1 AZT, DDI, 3TCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219Q E6ED, T27S, T39TA, K64H, T69N, D123E, D177E, I178IM, G196E, H208HY, R211K, L228H, A272S, I293V, E302DB
Bacheler (2000)LB4-P105P105-0 AZT, 3TCNoneM41L, D67G, K70R, M184V, K219Q K20R, V60I, T69N, K104N, I135T, I202V, R211GB
 LB4-P109P109-0 AZT, 3TCNoneM41L, K70R, M184V T69N, K122E, I135T, E169D, T200A, Q207E, F214LB
 LB4-P119P119-0 AZT, 3TCNoneK70R, M184V T69N, K122E, I142V, F214LB
 LB4-P122P122-0 AZT, 3TCNoneK70R, M184V K20R, K49R, T69N, S162N, F214LB
 LB4-P139P139-0 AZT, 3TCNoneD67N, K70R, M184V, T215V, K219Q K20R, K64N, T69N, V90I, K122E, R211K, D218EB
 LB4-P147P147-0 AZT, 3TCNoneK70R K20R, E29K, M41T, K43*, T69N, K102R, I178M, D185NB
 LB4-P153P153-0 AZT, 3TCNoneM184V E6D, V60I, S68G, T69N, D123E, I135T, Q207AB
Balotta (2000)CB-150CB-150AF252014AZT, D4T, 3TC, DDINoneD67N, K70R, M184V, T215F, K219Q V35I, T69N, R78RT, E89EK, S105SP, D123E, I135K, D177E, V179I, G196E, L228LHB
 CB-167CB-167AF252029AZT, D4T, 3TC, DDINoneD67N, K70R, M184V, T215F, K219Q T69N, K103R, V118I, D121N, D123E, I142V, T200A, F214LB
 CB-186CB-186AF251987DDC, AZT, D4T, 3TCNoneD67N, K70R, M184V, T215Y, K219Q K13KN, I31IL, I50V, K66KR, T69N, R83K, K122P, D123E, I135M, S162Y, D177E, E194EGB
 CB-194CB-194AF252040DDC, AZT, D4T, 3TC, DDINoneD67N, K70R, M184V, K219Q I5IM, A33AP, V60I, T69N, I135T, D218E, K238RB
 CB-210CB-210AF252060DDC, AZT, D4T, 3TCNoneD67N, K70R, T215V, K219Q T69N, V90I, D110DN, D123E, E138CY, T139TA, G141R, I180VB
 CB-226CB-226AF252081AZT, D4T, 3TC, DDINoneD67N, K70R, M184V, K219Q K20R, T69N, Q174H, I202V, Q207K, F214LB
 CB-279CB-279AF252088AZTNoneK70R K20R, T69N, R83K, A98S, D123E, E224EGB
 CB-293CB-293AF252010DDC, AZT, D4T, 3TC, DDINoneK70R, M184V T27S, S48E, I50IM, T69N, L80LF, R83K, P225PLB
Baxter (2000)GART-G63GART-63 NRTI, AZT, 3TCNoneM41L, K70R, M184V T69N, D123E, D177E, Q207E, R211KB
 GART-G64GART-64 NRTI, 3TC, DDINoneM184V T69N, R83K, V106I, K126N, S162A, E248DB
Falloon (2000)JF08JF08-(-)6wAF227719AZT, DDI, DDC, D4T, 3TCNoneD67G, K70R, M184V, T215F, K219Q K43KQ, K64R, T69N, V118I, I135M, G196N, T200I, I202V, E204Q, Q207E, R211K, F214L, V245TB
  JF08-12wAF227720AZT, DDI, DDC, D4T, 3TC, ABCNoneM41L, D67G, K70R, L74I, M184V, T215F, K219Q K43Q, K64R, T69N, V118I, F171Y, G196N, T200I, I202V, E204Q, Q207E, R211K, F214L, L228LH, V245TB
Katzenstein (2000)ACTG302_13171317RT_bl AZTNoneK70R E36D, T69N, D121Y, K122E, I135L, S162C, D177DE, I178IMV, V245MT, K277RB
Shulman (2000)CA1173CA9916AY802648AZT, DDI, 3TC, D4TNoneD67N, K70R, M184V, K219Q T27S, I31V, K64H, T69N, K122E, I195L, D218E, L228H, V245M, E248V, K249Q, A288T, I293VB
Venturi (2000)V2000-14V2000-14PAF158769AZT, DDI, D4T, 3TCNoneD67N, K70R, M184V, K219Q V60I, T69N, K103R, D113E, I159R, N175K, G196E, Q197K, Q207E, R211K, F214L, D218EB
 V2000-1V2000-1PAF158749AZT, DDINoneD67N, K70R, K219Q K49KR, T69N, I135TB
Albrecht (2001)ACTG364_156156 AZT, DDI, DDC, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q K20R, V35I, T39E, E44D, K64H, T69N, K103KR, I135V, I167V, H208Y, R211K, K223Q, L228H, V245T, I293V, E297AB
 ACTG364_22732273 AZT, DDCNoneD67N, K70R, T215F, K219Q T39AE, K64N, T69N, D123E, I142V, D177E, G196E, Q207E, H208HY, R211KB
 ACTG364_33063306 AZT, 3TCNoneD67N, K70R, M184V, K219Q V60I, T69N, K102Q, I135V, E203ED, D218E, T286A, L301LVB
 ACTG364_33183318 AZT, DDI, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q E6D, K43N, T69N, K104N, V179VI, I202V, H208Y, R211K, D218DE, V245I, D250E, S268SNB
 ACTG364_33343334 AZT, DDCNoneD67N, K70R, K219Q K64N, T69N, I142V, S162Y, E169D, G196E, E203K, H221HY, L228HR, T286A, I293VB
 ACTG364_34713471 AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q K20R, K43Q, V60I, T69N, I135V, S162Y, Q207QE, R211K, L228H, K277R, I293VB
 ACTG364_3535 AZT, DDC, DDI, 3TCNoneD67G, K70R, M184V, K219Q V35M, K64H, T69N, V118I, F214L, D218E, V245TB
 ACTG364_36093609 AZT, D4TNoneK70R E36D, V60VI, T69N, D121Y, K122E, I135L, S162C, I178M, V245T, K277R, R284RM, T290TA, I293VB
 ACTG364_54025402 AZT, DDI, 3TCNoneK70R K20R, V35I, T69N, R83K, K102Q, S134ST, I135T, E138EA, R211KB
 ACTG364_57075707 AZT, DDI, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q K20R, V35M, V60I, T69N, D123E, K154KE, S162C, I178L, Q207E, D218E, K238XB
 ACTG364_76637663 AZT, DDCNoneK70R T39TA, S48T, T69N, Q174L, Q207E, R211K, F214L, A272P, C280XB
Eshleman (2001)A004AF357608AF357608AZT, DDINoneD67N, K70R, T215TA, K219Q V35M, T39A, V60VI, K64KN, T69N, R83K, E138A, T165I, I178M, I202IV, F214FL, D218DE, A272P, T286A, V317AB
 A033AF357636AF357636AZT, DDINoneK70R V35T, T69N, I135V, Q207E, R211RK, V245M, D250E, K281R, L283I, I293VB
  AF357746AF357746AZT, DDI, D4T, 3TCNoneK70R, M184V V35T, T69N, I135V, Q207E, R211RK, V245M, D250E, K281R, L283I, I293VB
  AF357805AF357805AZT, DDI, D4T, 3TCNoneK70R, M184V K22KI, V35T, E36EG, K64R, T69N, I135V, Q207E, V245M, D250E, K281R, L283I, T286TA, I293VB
 A049AF357650AF357650AZT, DDINoneM41L, K70R, T215F K64KR, T69N, K102Q, I142V, S162C, T200I, Q207E, V245K, A272P, K277R, T286A, V292I, I293VB
 A063AF357664AF357664AZT, DDINone  V35I, T69N, R83K, D123E, D177E, I178M, V179C, R211RK, A272P, K281R, T286A, E297KB
 A065AF357666AF357666AZT, DDINoneK70R K20R, T69N, D123E, D177E, Q207E, R211K, Q242QH, P243PT, L283LI, T286TAB
  AF357763AF357763AZT, DDI, D4T, 3TCNoneK70R, M184V K20R, V21VI, T69N, D123E, D177E, Q207E, R211K, L283IB
 A103AF357704AF357704AZT, DDINone  K20R, T69N, V118I, D123E, D177E, I178M, Q207E, R211K, F214L, V245LQ, E248X, A272P, L283I, I293VB
 A113AF357714AF357714AZT, DDINoneK70R K20R, K64R, T69N, D123E, K166R, D177E, I178M, A272P, K277KR, I293V, V317AB
 A119AF357718AF357718AZT, DDINoneD67AT, K70R, T215F, K219EV108VIT69N, D123E, D177E, I178V, I195IT, I202V, Q207E, R211K, V241I, A272S, K277KR, K281R, T286A, I293IV, E297KB
Fitzgibbon (2001)JF-8JF8-M10AF444184AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, T215F, K219Q V35M, Y56S, T69N, K103R, V118I, K122E, I135T, K201I, H208Y, R211K, F214L, L228HB
  JF8-M14AF444185AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, T215F, K219Q K20R, V35M, T69N, K103R, V118I, K122E, I135T, K201I, H208Y, R211K, F214L, L228HB
Gonzales (2001)CA624CA1189AY030418DDI, D4T, 3TC, AZTNoneA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184EV S68G, T69N, V148VE, K166KR, D177DE, I178M, Y183Y*B
 CA1144CA2601AY030455AZT, DDI, DDC, D4T, 3TCNoneD67N, K70R, T215F, K219Q V35M, T69N, V118I, K122E, I135T, I202V, F214LB
 CA1147CA2608AY030458AZT, DDC, D4T, 3TCNoneM41L, K65KR, D67N, K70R, M184V, T215F, K219Q V60I, T69N, D123E, I142V, K166R, D177E, G196X, I202V, R211KB
 CA1390CA3640AY030544AZT, DDI, D4T, 3TCNoneD67N, K70R, M184V, K219Q V35T, T39A, K64H, T69N, D177E, I178M, Q207N, R211K, A272P, T286A, I293VB
 CA1496CA4276AY030622AZT, 3TC, D4T, DDINoneM41L, L210W, T215Y K43EQ, T69N, D123E, S162C, R172RG, D177E, I180IM, E203EDKN, Q207E, R211K, K223Q, L228RB
 CA1799CA4834AY030717D4T, 3TCNoneD67N, K70R, M184V, K219Q E6D, K20R, T69N, K103R, K122E, T200I, R211K, F214L, K311KR, R356K, A360V, A376T, A400T, L452LS, T470A, H483Y, G490GE, L491LS, K527KN, A554NB
 CA1809CA4854AY030724AZT, 3TC, D4TNoneD67N, K70R, M184V, T215V, K219Q K43KE, T69N, K103R, V118I, I135L, G196E, R211K, F214LB
 CA2084CA7712AY030792AZT, 3TC, D4T, DDC, DDINoneD67N, K70T, M184V, K219Q K20R, T39N, V60I, T69N, D123E, I135T, D177E, D218E, A272PB
 CA2190CA7950AY030815AZT, D4T, 3TCNoneK70R, M184V, K219Q T69N, V118I, V179I, F214L, L228R, P243H, V245EB
 CA2195CA7966AY030819AZT, DDC, D4T, 3TCNoneK70R, M184V I31R, T69N, F116FL, D123E, I135V, Q197E, F214FL, K259K*, T286A, E297AB
 CA2207CA8000AY030829AZT, DDC, 3TCNoneK70R, M184V T69N, R83K, S162C, T200A, E224D, A272P, V276T, K277R, K281R, I293V, E297KB
 CA3889CA9081AY030894AZT, D4T, 3TCNoneM41L, D67N, K70R, Q151M, M184V, T215F, K219Q K20R, T69N, V90I, I135V, S162A, D177E, G196E, E203DB
 CA3952CA9181AY030950AZT, DDI, 3TCNoneK70R, M184V T69N, I135L, D177E, R211NS, A272PB
 CA4016CA9275AY031012AZT, D4T, 3TCNoneM41L, K70R, M184V T69N, R83K, K122P, K173S, T200A, Q207E, F214FL, E233DB
 CA4104CA9406AY031095AZT, DDI, DDC, D4T, 3TCNoneD67N, K70R, M184V, T215V, K219Q V35M, T39TA, T69N, I135M, I178M, G196E, R211K, K281R, A288S, I293VB
 CA4464CA10937AY031308AZT, 3TC, D4T, DDINoneK70R T69N, D110DG, V118I, K122P, D177Q, G196E, Q207E, F214L, M230MV, T240A, V245VM, L246LVB
 CA4500CA10987AY031340AZT, 3TC, D4TNoneK70R, M184V T69N, V118I, I142T, T200A, F214L, T286P, E297KB
 CA4584CA11212AY031381DDC, AZT, D4T, 3TCNoneM41L, D67S, K70R, M184V, L210W, T215Y, K219E T39A, T69N, V106I, K122E, I178IM, E203D, H208Y, Q278H, A304GB
 CA4740CA11607AY031402AZT, DDCNoneD67DN, K70R, T215AV, K219KQ K49R, I50V, V60I, T69N, R83RK, D121H, K122E, I135T, D177E, R211K, T286AB
 CA4870CA11967AY031510AZT, D4T, 3TCNoneM41L, D67N, K70R, M184V, T215Y, K219Q T69N, K122E, I135T, E194A, G196E, Q197H, E203ED, V245K, T286AB
 CA4874CA11971AY0315143TC, DDI, DDC, D4TNoneM41L, D67N, K70R, M184V, T215F, K219Q K20R, T69N, W88C, K103R, D123E, I135IV, G196E, E203D, F214L, A272P, I293VB
 CA5006CA12277AY031581AZT, 3TC, D4T, DDINoneD67N, K70R, T215I, K219Q V60I, T69N, K102KQ, K103R, K122KE, F130FL, I135T, S162C, F214FL, D218E, A272PB
 CA5085CA12367AY031654AZT, 3TCNoneK70R, M184V K20R, S48T, T69N, I135V, Q207E, R211K, F214L, V245M, E297KB
 CA5321CA13033AY031876D4T, 3TCNoneM41L, D67G, K70R, L74I, M184V, T215F, K219Q K20R, K43KN, K64N, T69N, A129AG, T131TS, I142V, R143X, G196E, I202V, V245K, V261VL, K277R, A288AS, I293VB
 CA5978CA14749AY032225DDI, AZT, 3TCNoneD67N, K219Q V60I, T69N, I135T, D177DE, I202V, Q207H, R211K, F214L, L228LH, V245E, T286A, E297KB
 CA6348CA15832AY032307AZT, D4T, 3TCNoneD67N, K70R, M184V, K219Q K20R, T69N, K102R, K104R, K122E, D177DE, T215X, D218DE, P243X, V245E, A272P, V292I, I293V, E297KB
 CA6449CA15964AY032402AZT, DDI, D4T, 3TCNoneK70R, L74V, M184V, K219Q E6D, K64R, T69N, Q207E, F214L, A272PB
 CA6475CA15996AY032426AZT, 3TCNoneM41ML, A62AV, K70R, M184V K11KR, K43KE, T69N, R72RG, A98S, T200AV, R211K, A272S, A288T, V292I, E297AB
 CA6825CA16887AY032557DDC, AZT, 3TC, D4TNoneA62V, K70R, M184V T69N, W88WC, K122E, D123E, I135IT, E169D, I202V, Q207N, R211K, F214FL, A272P, E297K, A299AGB
 CA6832CA16895AY032564AZT, DDINoneD67N, K70R, T215TS, K219Q K43Q, T69N, S162X, I178M, T200A, E203EK, Q207E, R211RK, A272AP, K277RB
Katzenstein (2001)ACTG302_21452145RT_f1 DDI, AZT, 3TCNoneM184V V35M, T69N, A98S, D123E, G196E, R211RK, A272P, K281R, E297RB
 ACTG302_23442344RT_bl AZT, DDINone  T69N, D177E, I178L, I180IV, G196E, I293V, P294QB
  2344RT_f1 AZT, DDI, 3TCNoneM184V K11N, T69N, D177E, I178L, V179VI, G196E, I293V, P294QB
 ACTG302_31423142RT_bl AZT, DDINoneK70R K20R, V35I, T69N, R83K, K102Q, I135T, E138EA, Q197QL, R211KB
Perez (2001)EP-1877EP-1877AF320519NRTINoneD67N, K70R, M184V, K219Q E53D, K64H, T69N, V90I, K122E, F214L, V245EB
Servais (2001)JS10JS97442AJ401788AZT, DDCNoneD67N, K70R, T215Y, K219Q T69N, G196EB
Shulman (2001)302-270048270048 AZTNoneD67N, K70R, T215V, K219Q K20R, V60I, T69N, K104N, T200A, I202V, Q207AE, R211RK, T286A, I293VB
Cho (2002)OCH01OCH615AF407367AZTNoneM41L K20R, V60I, S68D, T69N, K122E, T200IB
 KKS99KKS12AF282150AZTNoneD67N, K70R, K219Q T69N, K103R, K122E, T200I, I202VB
Clevenbergh (2002)CP1902CP1902AF519424D4T, 3TCNoneA62V, V75I, F77L, Y115F, F116Y, Q151MY181CT69N, K122E, K173Q, Q174R, I202V, Q207E, R211K, V245TB
Cuevas (2002)CU21CU21AF425402AZT, 3TCNoneD67N, K70R, T215V, K219Q V60I, T69N, K104N, D123E, I135T, D177E, R211KB
Maxeiner (2002)410206a410206a+ AZT, D4TNoneK70R T69N, R83K, I135T, V292I, I326V, Q334L, M357T, A376T, T386I, A400T, L452LS, D460N, L517IB
Naugler (2002)WES-1HIV1ESAF422723AZT, DDINoneL74VK103N, Y181CA33V, V35T, T69N, R83K, D123EB
 WES-14HIV14ESAF422736AZT, DDINoneM41L, L210W, T215Y T39S, T69N, I135TB
 WES-16HIV16ESAF422738AZT, DDINoneD67N, L210W, T215Y K46L, T69N, D123E, I142T, G196S, R211KB
 WES-18HIV18ESAF422740AZT, DDINoneT215Y T69N, R83K, W88C, D123E, K166R, T200AB
 WES-22HIV22BLAF422719AZTNoneK70R, T215F T69N, R83K, D177E, R211KB
  HIV22ESAF422744AZT, DDINoneK70R, L74V, T215F T69N, R83K, D177EB
 WES-25HIV25ESAF422747AZT, DDINoneD67N, K70R, T215Y, K219E T69N, I135V, S162C, R211KB
Papa (2002)AP-28AP-28AF315776DDC, AZT, 3TC, D4T, DDINoneM41L, T215Y T69N, D123E, I135T, I142T, A158S, S162C, G196EB
Tural (2002)94609460 AZT, 3TC, D4T, DDINoneD67N, K70R, T215V, K219Q K20R, K43E, K49R, V60I, T69N, D123E, S162N, D177E, R211K, F214L, D218EB
 346735346735 D4T, DDI, AZT, 3TCNoneM184V S68G, T69N, K122E, I135T, R211KB
 880219880219 AZT, DDC, DDI, D4T, 3TCNoneM41L, D67N, K70R, F116Y, Q151M, T215F, K219Q K20R, V60I, T69N, V90I, S162H, R172K, H208Y, R211KB
 880407880407 AZT, 3TC, D4TNoneK70R, M184V T69N, R83K, I142T, K166R, N175S, F214L, V245T, D250EB
 880915880915 AZT, DDI, DDC, 3TC, D4TNoneD67N, K70R, T215F, K219Q V35M, T69N, A98S, K122E, R199K, T200V, V245MB
Venturi (2002)GV-54GV-54.1AF517306AZT, 3TCNoneM184V K49KR, T69N, R83K, A158S, S162C, D177E, I178M, V179I, Q207EB
 GV-57GV-57.1AF517309AZT, 3TCNoneM41L, K70R, M184V, T215Y K20R, V60I, T69N, R83K, K122E, I135TB
Gonzales (2003)CA630CA1201AF514000AZT, DDC, 3TC, D4TNoneD67N, K70R, M184V, T215Y, K219Q T69N, K102R, D218EB
 CA1127CA15951AF514015AZT, DDI, DDC, 3TC, D4TNoneD67N, K70R, M184V, T215FV, K219Q K20R, T69N, K102R, K122P, I135V, D177E, V179I, G196E, F214L, V245T, A272P, Q278H, T286A, I293IV, E297AB
 CA1130CA12328AF514017AZT, D4T, 3TCNoneD67N, K70R, M184V, K219Q K43E, T69N, K122E, D123E, Q174K, D177E, I178M, Q207E, R211K, F214L, A272P, V292VIB
 CA1272CA5021AF514042AZT, DDC, 3TCNoneD67N, K70R, M184V, T215F, K219Q T39TA, K64H, T69N, V90I, I135V, S162Y, D218DE, E224D, L228H, V245M, E248I, N265NT, A272P, C280CRB
 CA1390CA7767AF514059AZT, DDI, D4T, 3TCNoneD67N, K70R, M184V, K219Q V35T, T39A, K64H, T69N, Q174QR, D177E, I178M, Q207N, R211K, A272P, T286A, T290TA, I293VB
 CA1426CA7691AF514066AZT, D4T, 3TC, DDC, DDINoneD67N, K70R, M184V, K219Q V60I, T69N, K122KE, I135V, G196E, D218E, V245TB
Gonzales (2003)CA1531CA4386AY030649AZT, DDC, DDI, 3TC, D4TNoneM41ML, D67N, K70R, M184V, T215F, K219Q S48T, T69N, K122E, G196E, H208Y, D218E, V245M, A272P, A288ST, E297KB
Gonzales (2003)CA2311CA16938AF514151AZTNoneK70R E6EK, K64R, T69N, R83K, A98S, K104N, K122E, I135V, S162Y, T200A, I293V, E297K, A299AGB
Saah (2003)AS-13AS-13 AZT, 3TCNoneK70R, M184V V35I, T69N, I142V, G196EB
 AS-34AS-34 AZT, DDC, 3TC, D4TNoneM41L, K70R, M184V T69N, R83K, K122E, T200A, R211KB
 AS-39AS-39 AZT, DDC, 3TC, D4T, DDINoneM41L, D67N, K70R, T215F, K219Q V35I, K43N, V60I, T69N, A98S, K104N, D123E, I135V, L228HB
Delgado (2004)110366110366 AZTNoneD67N, K70R, T215F, K219Q K20R, T69N, K104N, D123E, Q207QP, R211K, T286AB
 110397110397 AZTNoneK70R T69N, R83K, D123E, D177E, T200TI, Q207DE, R211K, A272P, K281R, T286A, I293V, E297KB
Kuritzkes (2004)KDR_pat113A0135AY527952AZT, 3TCNoneD67N, K70R, M184V, K219Q V60I, T69N, K103R, F214L, P243TB
  A0136AY527953AZT, 3TCNoneD67N, K70R, M184V, K219Q V60I, T69N, K103R, I135IT, F214L, P243TB
Machado (2004)con20con20AY313406AZT, DDI, 3TCNoneD67N, K70R, M184V, T215F T69N, K104N, D121H, K122E, I135T, D177E, T200A, I202V, Q207E, F214L, K219P, K220EB
 con50con50AY313440AZT, DDINoneM41L, D67N, T215F, K219Q T39A, V60I, T69N, K104N, I135T, T200A, I202V, Q207E, R211KB
Garcia-Bujalance (2005)GBS_26GBS_26AY872361D4T, 3TCNoneD67G, K70R, M184V, K219E S68G, T69N, T84P, D113H, D123DE, I135T, S162C, Q174QR, G196E, R211KB
 GBS_36GBS_36AY872371AZT, DDC, D4T, 3TC, DDINoneA62AV, K70R, M184VV108IT69N, K122R, D123E, D177E, I178LB
Mo (2005)91899189_d1 NRTINoneD67N, K70R, M184V, T215F, K219Q E28A, K64H, T69N, D121Y, K122E, R211K, D218E, V245K, A272P, Q278QH, L283LI, R284RK, E297EKB
 89858985_d1 NRTINoneM41L, D67N, K70R, V75M, L210W, T215FY, K219HQK103N, V106A, F227LT39A, K43E, E44A, V60I, T69N, K102KR, V118I, K122E, I135V, I142V, D177N, I178M, G196E, E203EAKT, H208Y, D218E, V245KB
Rhee (2005)CA630CA3151AY800679AZT, DDC, 3TC, D4TNoneD67N, K70R, M184V, T215Y, K219Q K11X, T69N, K102R, D218E, I293V, E297KB
 CA801CA1447AY800727AZT, 3TC, D4T, DDINoneM41L, D67N, V75A, L210W, T215Y V35I, K43E, T69N, V118I, K122E, D123E, I135T, S162Y, Q207E, H208X, R211K, E224DB
 CA1127CA2536AY800746AZT, DDI, DDC, 3TC, D4TNoneD67N, K70R, M184V, T215F, K219Q K20R, T69N, K102R, K122P, I135V, D177E, V179I, G196E, F214X, V245TB
 CA1147CA19936AY800769AZT, DDC, D4T, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219QK101HT39TA, V60I, T69N, D123E, I142V, K166R, D177E, G196E, I202V, R211KB
 CA1170CA11998AY800798AZT, DDI, 3TC, D4T, DDCNoneD67N, K70R, M184V, T215V, K219E T69N, I135T, T200A, Q207E, E297KB
 CA1173CA2665AY800800AZT, DDI, 3TC, D4TNoneD67N, K70R, M184V, K219Q T27S, I31V, K64H, T69N, K122X, I195L, D218E, L228H, V245M, E248V, K249QB
 CA1333CA37803AY800883D4T, 3TCNoneK70R, M184V K20R, V60I, T69N, I135V, I142V, E203EA, R211KB
  CA37804AY800884D4T, 3TCNoneK70R, M184V K20R, V60I, T69N, I142V, R211K, V245IB
 CA1426CA8458AY800923AZT, D4T, 3TC, DDC, DDINoneD67N, K70R, K219KQ T58TN, V60I, T69N, K122E, I135V, N137NI, L193LF, G196X, P226PS, L234LH, V245MTB
 CA3952CA14110AY801217AZT, DDI, 3TCNoneK70R, M184V T69N, I135L, D177E, R211NS, N265NS, A272PB
 CA4016CA34337AY801247AZT, D4T, 3TC, ABC, DDINoneD67DN, K70R, M184V T69N, R83RK, K102KR, K122P, N136ND, I142IV, K173S, D177DN, T200A, Q207E, F214L, P243PT, V245E, A272P, K277R, T286A, I293V, T296S, E297KB
 CA4360CA10558AY801312AZT, 3TC, D4T, DDINoneM41L, K70R, L210W, T215Y V60I, T69N, A98S, K122E, D123S, I135T, I142V, A158AS, S162AD, V245E, I293V, E297AB
 SWC-61006100-306 DDC, NRTI, D4T, 3TCNoneK70R T69N, K122KEB
 SWC-8546P8546-1256 AZT, DDC, 3TC, D4TNoneK70R, M184V, K219Q K64H, T69N, A98S, V179T, T200E, F214LB
 CA5175CA37859AY801506AZT, 3TC, DDINoneD67N, K70R, T215V, K219Q V35VI, V60I, T69N, D121H, K122E, I135T, I178M, T200A, R211T, D218E, K277R, Q278E, I293V, E297RB
 CA5990CA38037AY801625AZT, 3TC, D4T, ABCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219E K20R, V35K, T39A, K49KQ, T69N, W88C, A98S, K122E, D123E, I135IT, V179I, G196E, T200A, E203K, Q207E, R211RK, F214L, L228H, V245M, A272S, K277R, A288S, E297KB
 CA5998CA48164AY801629AZT, D4T, 3TC, TDFNone  V35VL, T69N, E169D, D177E, I178M, T200A, K201R, Q207E, F214L, V245T, E248V, A272P, R284K, I293V, D324E, I329LB
 CA6825CA48188AY801706DDC, AZT, 3TC, D4T, TDFNoneA62V, K70R, M184V, K219Q K49KR, T69N, K122E, D123E, I135T, E169D, T200A, Q207N, R211K, F214L, A272P, I293IV, E297KQB
 CA6832CA21200AY801707AZT, DDI, D4TNoneD67N, K70R, K219Q K43Q, K64KN, T69N, S162A, I178M, T200A, E203K, Q207E, K277R, I293VB
 CA6881CA16955AY801730AZT, DDC, 3TCNoneD67N, K70R, M184V, T215F, K219Q K20R, V60I, T69N, V118I, I135T, I142V, G196E, F214L, V245M, R284K, I293VB
 CA7988CA20078AY801884AZT, 3TC, D4T, DDINoneD67N, K70R, K219Q K20R, V35M, T39AE, N54NK, V60I, K64H, T69N, I135T, E138A, I202V, F214L, L228H, T286A, I293VB
 CA8015CA20128AY8019043TC, D4TNoneM41L, K70R, M184V T69N, K122E, I135T, E169D, R211K, A272P, I274IM, A299AGB
 CA8037CA20166AY801921AZT, DDC, D4T, 3TCNoneD67G, K70R, M184V, K219Q K64H, T69N, T200A, R211K, F214L, D218E, K277RB
  CA48180AY801922AZT, DDC, D4T, 3TCNoneD67G, K70R, M184V, K219Q K64H, T69N, V118I, Q174QR, V179VI, T200A, R211K, F214L, D218E, K277R, I293V, T296TS, E297RB
 CA8395CA42658AY801993AZT, 3TC, D4T, DDINoneD67N, K70R, T215F, K219Q T39TA, K64H, T69N, K122P, I142V, Q174QR, D177E, I178L, R211RK, A272P, T286AB
 SWC-85468546-2041 AZT, DDC, 3TC, D4TNoneK70R, M184V, T215V, K219Q K64H, T69N, A98S, V118I, V179I, T200E, F214LB
  8546-2958 AZT, DDC, 3TC, D4TNoneK70R, M184MV, T215V, K219Q K64H, T69N, A98S, V118I, V179I, T200E, F214LB
  8546-3393 AZT, DDC, 3TC, D4TNoneD67G, T215V, K219Q V35I, K64H, T69N, A98S, V118I, V179T, T200E, R211K, F214L, S251NB
 CA9799CA24066AY802121AZT, 3TCNoneD67N, M184V, K219QE138KI31V, T69N, D123E, D177E, G196E, D237E, K277R, T286TA, I293V, E297AB
  CA34963AY802122AZT, 3TCNoneD67N, M184V, K219QE138KI31V, T69N, D123E, I135V, D177E, G196E, D237E, K277R, T286A, I293V, E297AB
 CA9881CA24385AY802161AZT, 3TC, D4T, DDINoneD67N, K70R, K219Q T39A, K64N, T69N, K103R, K122E, I135L, F214LB
 SWC-51665166-2379 AZT, 3TCNoneK70R, M184V K64R, T69N, K122R, D123E, I135T, S162C, T200AB
 CA14385CA34645AY802329AZT, 3TC, ABCNoneM41L, D67T, K70R, L74LI, M184V, L210LW, T215F, K219E V35M, K43X, T69N, I135IT, I167IV, G196E, I202IT, E203ED, K277R, R284K, I293V, M357T, A360V, A400T, F416Y, V458I, D460S, K512R, K527KQB
 CA14449CA42758AY802343AZT, 3TC, ABCNoneD67N, K70R, M184V, K219Q K11KRT, T39TS, T69N, K122P, D123S, L210F, V245KB
 CA16241CA38627AY802459D4T, 3TCNoneD67DN, M184V K20R, T69N, A98S, D123DEKN, D177E, Q197E, F214L, A272P, K277R, L283I, I293VB
 CA16262CA38675AY802466AZT, D4T, 3TC, ABCNoneM41L, D67HN, K70R, L74I, M184V, L210W, T215F, K219QA98GV8VI, K20R, T39TAEK, V60I, T69N, K122E, I135T, S162SN, K166R, G196E, H208Y, R211K, D218E, A288S, I293V, I329V, G333E, R356K, A371V, K390R, E399D, K454R, V466T, V467I, H483Y, E492D, S519N, Q547R, A554TB
 CA17673CA41589AY802539AZT, 3TC, D4T, DDINoneK70R K20R, T69N, S162SN, D177E, G196GR, Q197E, R211K, F214L, A272P, L283I, I293VB
Riddler (2008)RG50847RG50847w7 TDF, 3TCNoneD67N, T215I, K219QY181C, Y188LV35L, V60I, T69N, K103R, K122E, S163T, G196E, R211KQ, V245T, E248ED, K249KR, K277R, E297K, L301M, G359S, A376S, T377L, S379A, K390R, Q394LB
  RG50847w15 TDF, 3TCNoneD67N, T215I, K219QY181C, Y188LV35L, V60I, T69N, K103R, K122E, S163T, G196E, R211Q, V245T, K249KR, K277R, E297K, L301M, G359S, A376S, T377L, S379A, K390R, Q394LB
 RG55256RG55256w18 AZT, 3TCNone  T69N, K122E, I135T, S162C, I178M, R211K, I293V, M357T, T369A, S379SGB
Rosen-Zvi (2008)7201p72-1 AZT, DDI, DDC, 3TC, D4TNoneK70R, M184V T69N, D121Y, K122E, D123E, I135T, I142V, V179VI, G196E, F214L, A272P, K281R, I293V, E297KB
Rhee (2009)CA16317CA38787FJ983414D4T, 3TC, TDF, DDINoneM41L, L210W, T215Y K20R, T69N, K122E, D123N, T200I, R211K, K277KT, T286A, I293V, E297K, I326V, Q334L, R356K, A360T, K366R, A371V, A376T, D460N, R461K, Q480H, A554NB
von Wyl (2010)15403151540315GQ848111AZT, 3TCNoneM41L, K70R, M184V V60I, T69N, I135T, I142V, T200A, T286A, I293V, E297K, E312EQ, D324E, G359S, A371V, A376TB
 65526552GU3010883TCNoneM184V K20R, T69N, R211K, E248D, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519NB
Mollan (2012)MK35MK35w17 TDF, FTCNone  V35VI, V60VI, T69N, R83K, K122KE, S162A, V245M, A272PB