<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation D67E
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 12
Patients 21
Isolates 22
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ruiz (1996)JCS-C41C41W24Z99330DDC, AZT, 3TCNoneM41L, D67E, L210W, T215Y V35I, S68G, K122E, I135T, T200IMB
Hammer (1997)ACTG320_26482648 AZT, DDI, DDC, D4T, 3TCNoneM41L, A62V, D67E, L210W, T215Y K43Q, I50IV, S68MV, W88C, V118I, K122E, S162SG, N175Y, R211K, A272P, K277R, I293IV, I329V, G333E, G359S, A371V, A376T, A400T, K451KR, D460N, Q487QHB
 ACTG320_42814281 AZTNoneM41L, D67E, T215Y E6EG, V35T, V60I, S68G, D86DE, I135V, Q197E, T200A, Q207E, A272S, A288S, I293V, T338S, R356K, M357T, G359S, T377M, S379C, A400AT, T403TI, E404D, F416FY, A437V, K465R, L469I, L491SB
 ACTG320_989989 DDC, AZT, D4TNoneM41L, D67E, L210W, T215Y V35I, T39A, S68G, K104KN, V118VI, I135T, W153WL, K166R, T200S, R211RK, V245T, A272P, I293V, I329IL, Q334D, K347Q, G359S, K390R, T403I, V435VA, L452M, S468PB
Cabana (1999)Cab-bB0AF102334DDC, AZTNoneM41L, D67E, L210W, T215Y K43R, S68G, K122P, D123E, I135T, S162C, D177E, R211KB
  B58AF102335DDC, AZT, 3TC, D4TNoneM41L, D67E, V75M, F77L, M184V, L210W, T215Y E40F, K43E, S68G, V118I, K122P, D123E, I135T, L149I, S162C, D177E, Q207E, R211KB
Masquelier (1999)DRO-22DRO22BAJ239270AZT, DDINoneM41L, D67E, L210W, T215Y S68G, K122E, S162C, G196EB
Albrecht (2000)ACTG303_496496RT_f1 AZT, DDI, 3TCNoneM41L, D67E, L210W, T215Y E44D, S68G, K173E, I178L, Q207E, V245K, A272PB
Balotta (2000)CB-4CB-4AF186769AZT, DDC, D4T, 3TCNoneD67E, T69S_SG, L210W, T215YA98GP4S, K20R, V118I, K122E, K154KE, K173T, G196E, R211K, L228HB
Albrecht (2001)ACTG364_12121212 DDI, AZTNoneA62V, D67E, K70R, V75T, T215TI, K219Q K20R, T27S, I37L, S68G, V118I, K122E, E203D, F214L, L228H, A272P, Q278QE, T286AB
 ACTG364_33083308 AZT, DDI, 3TCNoneM41L, A62V, D67E, K70R, F116Y, M184MIV, L210W, T215Y V35I, T39TA, T69S, V90I, V118I, K122KE, S162C, E203EK, R211S, L228H, A272P, K277R, E300X, L301X, A304XB
 ACTG364_57105710 AZT, DDI, 3TCNoneA62V, D67E, K70R, T215F V35I, T69S, V118VI, I135T, K173N, G196E, A272P, K277R, Q278H, E297KB
Gonzales (2001)CA4723CA11585AY031385AZT, DDI, DDC, 3TCNoneM41L, D67E, M184V, L210W, T215Y E44D, S68G, D123E, D177E, I178M, R211K, Q278QHB
 CA4782CA11674AY031442AZT, D4T, 3TCNoneD67E, K70R, M184V, K219Q K20R, S68G, I135V, F214L, A272P, T286A, A288S, I293V, E297AB
 CA5965CA14730AY032212AZT, 3TCNoneM41L, D67E, M184V, L210W, T215Y K11R, E44D, S68G, K122E, I135T, I142IV, R211K, I293VB
Katzenstein (2001)ACTG302_18931893RT_f1 AZT, DDI, 3TCNoneM41ML, A62V, D67E, K70R, F116Y, M184I, L210W, T215Y V35VI, T69S, R83RK, V90I, V118I, S162C, T165TI, R211S, L228H, A272P, K277R, R284RIB
 ACTG302_35883588RT_f1 AZT, DDI, 3TCNoneA62V, D67E, K70R, T215F K20KT, V35I, T69S, I135T, A158AS, K173N, G196E, A272P, K277R, Q278H, E297KB
Clevenbergh (2002)CP0937CP0937AF519428NRTI, D4T, DDINoneA62V, D67E, T69S_SG, K70R, T215F V118VI, K122E, D123S, D177DE, Q207E, R211KB
Machado (2004)cs160cs160AY313394AZT, DDI, 3TCNoneM41L, D67E, V75M, F77L, M184V, L210W, T215Y T39A, E44D, S68G, V118I, D123E, I135T, E138A, I142T, Q197L, R211KB
Montes (2004)MB_patGUZ01_GUZ714AJ577908ABC, AZT, 3TCNoneD67E, K70R, Y115F, M184V K49R, V90I, D123E, T165I, I202V, E204D, F214LB
 MB_patGUZM01_GUZ814AJ577909ABC, AZT, 3TCNoneD67E, K70R, Y115F, M184V K49R, V90I, D123E, T165I, I202V, E204D, F214LB
 MB_patGUZM J01_GUZ914AJ577910ABC, AZT, 3TCNoneD67E, K70R, Y115F, M184V K49R, V90I, D123E, T165I, I202V, E204D, F214LB