<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation E40D
Rx RTI-naive
IncludeMixtures No
References 73
Patients 206
Isolates 206
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Miller (2000)MV-103MV-103bd0 NoneNone  V35T, E40D, K43R, K49R, V60I, N81ND, K122E, D123G, I135T, T165I, D177E, I178M, T200I, Q207D, R211KN, D218DNB
Perno (2001)PCF_Pat6PCF1158AF376570NoneNone  V35T, E40D, V60I, R83K, K102KM, D123E, V245E, A272P, I293IV, E297K, L301IB
 PCF_Pat186PCF1503AF376585NoneNone  M16T, V35T, T39A, E40D, R83RK, D123E, G196E, A272P, K277R, I293IV, T296S, E297KB
Machado (2002)185cdpol185AF373722NoneNone  V35T, E40D, V60I, V118I, D123E, D177EB
Podzamczer (2002)48BAA139832 NoneNone  K20R, V35M, T39A, E40D, R83K, K122E, I135T, S162Y, A272P, A288S, I309IT, K311R, Q336E, K350R, M357I, K390RB
Vidal (2002)VC_pat296VC296-1AF517067NoneNone  E40D, R83K, E89K, G196E, I202IVB
Shafer (2003)A384_18131813aEF548404NoneNone  E40D, A98S, K122E, I135IATV, T165I, I195T, T200A, E204K, Q207E, F214LB
 A384_34403440aEF549015NoneNone  E40D, D123E, D177E, I178V, Q207EB
 A384_56085608aEF549136NoneNone  E40D, D121H, K122E, I135V, S162C, K173KQ, D177DE, Q207E, L210M, P243PSB
 A384_39173917aEF549175NoneNone  E40D, R83K, D123E, T165TI, D177DE, R211K, V245EB
Vaughan (2003)VHE_Pat47VHE034prrtAY267283NoneNone  V35I, E40D, K122P, S162C, E169D, K173Q, Q174K, D177E, T200A, E204D, Q207A, R211KB
Espinosa (2004)5353AY140147NoneNone  V35T, T39L, E40D, K122E, Q207E, R211K, D250E, A272P, K281R, I293V, P294Q, E297RB
Gulick (2004)RG240RG240w0 NoneNone  T39E, E40D, K49R, R83K, K173Q, I178IM, Q207E, R211KB
 RG246RG246w0 NoneNone  E40D, R83K, K122E, D123N, S162A, D177E, Q207E, R211KB
 RG78RG78w0 NoneNone  T39A, E40D, V118I, K122G, D123E, K173N, Q174K, I178L, G196E, T200A, Q207E, R211K, F214L, P243H, V245EB
Kijak (2004)1918LE02CM.1918AY371169NoneNone  V35T, T39N, E40D, K49R, V60I, T107S, D123E, I135T, S163T, E169G, P170T, K173A, Q174K, D177E, Q207E, R211K, V245K, K275Q, K277R, T286A, E291D, V292I, I293V, E297V, E312N, D324E, I329V, Q334D, F346Y, R356K, M357G, R358G, G359S, T369A, E370A, S379G, T386I, K390R, A400T, E404D, V435I, K454R, D471E, Q480H, L491S, L517I, S519N, A534S, A554NB
Yerly (2004)296LS99_296AY562431NoneNone  V35T, T39A, E40D, K49R, N57Y, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, R211K, F214LB
 177LS99_177AY562432NoneNone  V35T, T39A, E40D, K49R, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207K, R211K, F214LB
 677LS99_677AY562435NoneNone  V35T, T39A, E40D, K49R, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207K, R211K, F214LB
 600LS01_600AY562436NoneNone  V35T, T39A, E40D, K49R, K122KE, I135R, E169D, K173T, D177E, Q197K, T200E, I202V, R211K, F214LB
 784LS01_784AY562443NoneNone  V35T, T39A, E40D, K49R, I135R, M164L, E169D, K173T, D177E, I178IM, Q197K, T200E, I202V, R211K, F214LB
 858LS02_858AY562473NoneNone  V35T, T39A, E40D, K49R, I135T, E169D, K173T, D177E, E194K, Q197K, T200E, I202V, Q207K, R211K, F214LB
 176LS02_176AY562474NoneNone  V35T, T39A, E40D, K49KR, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207K, R211K, F214LB
 172LS02_172AY562485NoneNone  V35T, T39A, E40D, K49R, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207K, R211K, F214LB
 163LS02_163AY562487NoneNone  V35T, T39A, E40D, K49R, I135T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207K, R211K, F214LB
Escoto-Delgadillo (2005)64GDLEVV-RT_64GU291877NoneNone  E40D, K102Q, K104R, Q174K, I178IM, V179I, Q207E, R211KB
Grossman (2005)2792227922RT468 NoneNone  T39I, E40D, K122KE, D123DE, F214LB
Non-B Workgroup (2005)UK2049UK2049 NoneNone  V35T, E40D, V60I, D76N, L80LF, D121H, K122E, S162C, I178L, Q182QHB
Carr (2006)101BA101BADQ826726NoneNone  V35T, T39N, E40D, K49R, V60I, K104R, D123E, I135T, T139A, P170T, K173A, D177E, Q207E, R211K, V245N, E248D, A272P, T286A, E291D, V292I, I293V, E297A, E312D, F346Y, R356K, M357R, R358G, G359S, A376C, K390R, A400T, E404D, E413D, E432D, V435I, D471E, Q480H, H483Y, L491S, K512N, L517I, S519N, A534S, A554SB
Lama (2006)Pt46044604 NoneNone V179DV35T, E40D, V60I, K122E, D123N, I178M, R211RK, F214L, V245T, A272P, T286TA, V317A, Q334LB
 Pt56505650 NoneNone  I5V, K20R, V35I, E40D, D86E, W88C, I135V, F171Y, R211K, F214L, V245Q, D250E, T286A, E297K, L301M, H315Q, V317A, I329LB
Lindstrom (2006)SIIDC0292SIIDC0292 NoneNone  K20R, V21I, V35T, T39A, E40D, K49R, D123E, I135T, S162C, F171Y, P176AITV, D177DN, G196E, I202V, R211GB
 SIIDC0168SIIDC0168 NoneNone  K20R, E40D, V60I, D123E, D177E, I178L, Q207E, V245QB
Saad (2006)MDS_02UANK09002UANK090DQ055328NoneNone  V35I, E40D, K101R, K122P, I142T, D177E, Q207DB
Brumme (2007)1596PRRT_1596EF368906NoneNone  V35T, E40D, K49R, D123E, K166KR, D177E, R211RK, K277R, T286A, I326V, I329V, Q334N, K347KR, R356K, M357L, A360T, K388R, K390KRB
Eyer-Silva (2007)BRSQ8606BRSQ86EF042682NoneNone  V35M, E40D, S48T, V60I, K122E, I178M, V189I, R211KB
Gatanaga (2007)C03-51110117-1C03-51110117-1AB640217NoneNone  V35I, I37M, T39S, E40D, K49R, I135L, S162C, E169D, E194H, G196EB
Holguin (2007)575505575505EF583187NoneNone  K20R, K32R, V35T, T39A, E40D, K49R, V60I, K122E, I135T, S162SN, I202V, F214L, A272P, T286TA, V292I, K311R, A327AVB
 612457612457EF583259NoneNone  E40D, V118VI, K122E, E169D, R211Q, F214L, A272P, I293V, P294Q, K311KR, Q334EB
Sanchez Onoro (2007)533970533970 NoneNone  V35T, T39A, E40D, V60I, D123E, I135T, I142V, E169D, R211K, F214L, V245M, A272P, K277R, T286A, K311RB
von Wyl (2007)475502826EF449863NoneNone  V35I, E40D, K122E, D123N, I135T, D177E, I178M, F214LB
Chang (2008)TW5592aTW5592a NoneNone  E6D, V21I, V35T, T39ALSV, E40D, V60I, R83K, H96HP, K166R, D186DN, Q207E, V245EB
Holguin (2008)SP6-344898SP6-344898EU255491NoneNone  E40D, V60I, V118I, K122E, I135T, S162A, E169D, Q174K, G196E, R211K, F214LB
Miura (2008)BEC121BEC121EU518011NoneNone  E6K, E40D, E42EK, A98S, D123E, S162C, Q207E, R211K, A272P, K277R, I293V, E297K, K311N, P321E, Q334L, K390R, A400T, E404D, V417I, V435I, D460N, G490GE, L491S, K527R, A554TB
Palacios (2008)1255312553 NoneNone  T39A, E40D, K49R, D123E, I135T, S162C, F171Y, D177E, G196E, I202V, E204EK, R211G, V245QB
Riddler (2008)RG48271RG48271w0 NoneNone K103NV35T, T39A, E40D, D123E, S162C, K173R, Q207K, R211K, P243T, V245M, A272P, K277R, T286A, V292I, I293VB
Yamaguchi (2008)J11233J11233EU697906NoneNone  V35T, T39N, E40D, V60I, K104R, I135L, S162G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245E, A272P, K275Q, E291D, V292I, I293V, E297A, E312N, D320E, D324E, I329V, F346G, M357R, R358G, G359S, T377I, K390R, A400T, E404D, E432D, V435I, N447NS, L452LV, R461K, D471E, Q480H, L491P, L517I, S519N, K530KR, A534S, A554NB
Ayouba (2009)0.2160.216-LRTGQ351856NoneNone  E40D, K49R, V60I, D121Y, K122E, D123G, T165I, K173N, D177E, Q207EB
Brennan (2009)A45ARC-A45EU711457NoneNone  V21VI, E40D, K122E, D123E, K173E, D177E, I178V, I202V, A272P, E291ED, I293V, P294P*QS, V317AB
Brumme (2009)B4522B4522GQ371798NoneNone  V35I, E40D, K104R, V118I, T165I, R211K, F214L, A288S, V292I, I293V, Q334E, M357T, K390R, A400T, T403S, K451R, L452V, S468P, A502T, S519NB
de Sa-Filho (2009)5945959459IthGQ294596NoneNone  E6A, V8I, V35T, E40D, V60I, K122E, S134SR, N136NT, T139TK, R211KB
Nadai (2009)CRC08794CRC08794EU439759NoneNone  V35I, E40D, K122Q, S162C, E169D, K173Q, Q174K, D177E, T200A, E204D, Q207A, R211RKB
 DR148445DR148445EU439768NoneNone  V35I, E40D, K103R, K122E, D123DE, T200V, Q207E, R211K, F214LB
 DR151077DR151077EU439770NoneNone  E6G, V35T, T39A, E40D, K49R, K122E, D123N, I135T, S162C, D177E, Q207EB
Smith (2009)PI346US2001PI346 NoneNone  E40D, I135V, T165I, E169D, Q197E, A272P, K277R, P294PSB
Vercauteren (2009)pt17742688283782GQ399250NoneNone  K20R, V35T, E40D, K49KR, K122E, D123DN, I135T, Q207A, R211K, V245M, V292I, E297KB
 pt17472911063145GQ399277NoneNone  E40D, K122Q, T165TI, Q197K, T200I, I202V, R211RKB
 pt16943178942273GQ399330NoneNone  V35L, E36N, I37F, E40D, K104N, K122E, I135T, K166R, D177E, V179VI, R211K, F214LB
 pt15583985551292GQ399466NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, E40D, V60I, K101R, I142T, R211K, V245QB
 pt13075358574086GQ399717NoneNone  K32KR, V35MT, T39A, E40D, R83K, D121DH, D123E, D177E, Q207E, R211K, E248D, T286A, E291ED, V292VI, E297R, L301I, I329LB
 pt12855467312931GQ399739NoneNone  V35T, E40D, A98S, K122P, Q174QR, R211H, K281R, T286A, I293IV, V317A, I326V, A327VB
 pt9627474924530GQ400062NoneNone  V35L, E36N, I37F, T39TK, E40D, K102R, S162H, Q174N, D177E, G196E, R211TB
 pt8897909031548GQ400135NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, E40D, K49R, R83K, K122E, E169D, D177E, I178L, G196E, I202V, R211K, V245MB
 pt7318742932695GQ400293NoneNone  V35L, E36N, I37F, E40D, N57NK, D86E, E204Q, R206RI, R211KQB
 pt5439672542925GQ400481NoneNone  V35L, E36N, I37F, E40D, Q174H, Q207E, R211KB
 pt360hU0WLlIrduGQ400664NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39A, E40D, K122E, D123G, I135T, T200A, I202V, R211KB
 pt358HvfZ3eNb2YGQ400666NoneNone  V35T, T39A, E40D, K122KE, S162C, R211A, S251H, K277R, A288ASB
Yebra (2009)SP75-392005SP75-392005EU362927NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, E40D, K49R, V60I, V118I, K122E, T165I, I178L, V179I, T200A, E204K, Q207E, F214LB
Castelbranco (2010)090015A090015AHM357732NoneNone  T39L, E40D, V60I, D121Y, K122E, I135L, N175H, D177E, I178V, Q197QH, E204Q, R206K, Q207E, R211K, F214L, L228H, I244VB
 090035A090035AHM357739NoneNone  T39A, E40D, K49R, V60I, T107S, D121Y, K122E, D123G, D177E, Q207E, R211K, I244IV, V245MB
Descamps (2010)289odyssee289odysseeHQ718122NoneNone  V35M, E40D, R83K, K122P, S162N, T165I, D177E, G196E, L210F, R211KB
 437odyssee437odysseeHQ718270NoneNone  V35T, E40D, K173R, D177G, R211KB
Ferreira (2010)P55DIP55GQ862310NoneNone  E28G, E29K, E40D, I135T, I142V, S162A, I195L, A272P, I274V, Q278H, T286A, E297K, E312KB
Mosha (2010)S11PolS11PolJQ071459NoneNone  V21I, V35T, T39A, E40D, V60I, K122E, D123G, I135T, K173S, Q174K, T200A, Q207A, R211S, V245K, D250E, A272S, L282C, L283I, T286A, E300A, A304G, E308K, P321S, K331N, P345Q, A360T, T377Q, S379C, K390R, A400TB
Ragonnet-Cronin (2010)PHAC_290PHAC_290HM468788NoneNone  K11R, K20R, E40D, V60I, D123E, D177E, I178M, E203EG, R211K, K220KE, A272P, T286A, E298EKB
 PHAC_337PHAC_337HM468835NoneNone V179DK20KR, V35T, E40D, V60VI, S162C, T200IV, V245E, A272P, T286A, P294AB
 PHAC_356PHAC_356HM468854NoneNone  V35T, T39K, E40D, K49R, V60I, D121Y, K122E, D123G, D177E, I178M, T200I, Q207D, R211K, V245E, D250E, I257L, A272P, K277R, K281R, L282C, T286A, I293VB
 PHAC_419PHAC_419HM468917NoneNone  K11R, K20R, E40D, V60I, D123E, D177E, I178M, R211K, A272P, T286AB
 PHAC_440PHAC_440HM468938NoneNone  E40D, K104N, V106I, S162Y, Q174E, V179I, G196E, R211G, A272P, K277R, I293VB
 PHAC_709PHAC_709HM469207NoneNone  V35T, E40D, K49R, D123E, I142V, T165I, D177E, T200A, I202V, Q207QH, R211K, A272P, K277R, L283I, V292I, I293V, L295F, E297QB
 PHAC_742PHAC_742HM469240NoneNone  E6D, V35T, T39A, E40D, K122E, S162C, I178L, V179I, E204T, R211K, V245E, A272P, K277R, L283I, V292I, K311KRB
 PHAC_778PHAC_778HM469276NoneNone  E40D, S48T, K64KR, D121H, K122E, S162A, D177E, G196E, Q197K, R211G, V245E, A272P, K277R, I293V, E297A, I309INB
Yebra (2010)24942905SP0249429FJ481762NoneNone  V35VIM, E40D, V60VI, R83K, D123E, S162Y, K166KR, D177E, R211RG, L228LF, A272P, I274IV, K281KR, A288S, E297KB
 29641806SP0296418FJ481838NoneNone  E40D, S48T, K122E, D123DE, S162C, G196E, T200IB
Chibo (2011)S62S62JF895249NoneNone K103NE28EK, V35T, E40D, V60VI, K122E, V179I, T200TA, V245EB
 S173S173JF895360NoneNone K103NV35T, E40D, V60I, S117SP, K122E, V179I, T200I, V245EB
El Annaz (2011)39353935HQ393342NoneNone  V35M, T39A, E40D, R83K, K102Q, Q151K, T200A, F214SB
 39373937HQ393343NoneNone  V35M, T39A, E40D, R83K, K102Q, K122Q, K166R, D177E, T200A, R211KB
 65996599HQ393361NoneNone  V35I, E40D, K103R, V118I, K122E, I135T, D177E, V179I, G196E, R211S, F214LB
Graf (2011)SC37SC37JF774004NoneNone  V35T, T39K, E40D, K49R, D123E, I135L, S162C, E169D, K173T, Q174K, T200A, Q207E, R211K, V245M, A272P, K277R, T286P, E297K, P321S, D324EB
Kao (2011)Pat09036520HQ657950NoneNone  E6D, V35I, E40D, V60I, R83K, Q207E, R211K, V245L, E312T, Q330PB
Mezei (2011)3014HU3014JF419430NoneNone  E40D, S48T, V60I, D121H, K122E, I135T, S162A, D177E, G196E, T200I, R211GB
 3043HU3043JF419436NoneNone  E40D, S48T, V60I, D121H, K122E, I135T, S162A, D177G, G196E, T200I, R211G, V245EB
 3071HU3071JF419442NoneNone  E40D, S48T, V60I, D121H, S162A, D177E, G196E, T200I, R211GB
Rolland (2011)1478consensus_1478JF320150NoneNone  V35T, E40D, T165I, G196E, Q197K, K277R, D324E, I329V, G333E, Q334N, T369A, A376T, K390R, A400T, K431R, V435A, S468P, H483N, A554S, K558RB
 1512consensus_1512JF320356NoneNone V179DK20R, E40D, K122P, D123E, S162C, D177E, I195L, Q207E, R211K, F214L, A272P, A288S, V292I, E297N, P313T, V317A, G333E, M357T, R358K, K366R, A376T, T386I, K390R, A400T, V435I, N447S, R461K, Q509H, V548IB
Truong (2011)0600233206002332JX073443NoneNone  I37X, E40D, I135T, S162C, V189IB
Avila-Rios (2012)JCV0M7KFU0JCV0M7KFU0KC169110NoneNone  K32KR, V35T, T39L, E40D, K102R, K103R, V118I, D121H, K122E, I135T, S162C, K173KR, G196E, T200A, Q207H, R211T, F214L, V276I, T286A, E297KB
 JV00M8T5WXJV00M8T5WXKC169143NoneNone  V35M, E40D, V60I, K104R, V118I, D123N, I135T, I142L, T165I, G196E, F214L, A272S, K277R, I293V, E297AB
 JW00M62RU3JW00M62RU3KC169149NoneNone V179EV35I, E40D, R83K, K122P, Q197QL, T200TAIV, R211K, K277R, A288S, I293V, E297V, S322TB
 JX00M51TS6JX00M51TS6KC169152NoneNone V179EM16V, V35I, E40D, R83K, K122P, Q174QR, D177DG, T200A, I202V, R211K, A288S, I293V, E297V, S322AB
 M000F98KTGM000F98KTGKC169162NoneNone  P4L, V35T, E40D, D123E, K281R, T286A, I293V, P294T, E297K, L325IB
 M0CFM68ISMM0CFM68ISMKC169240NoneNone E138EKV35M, E40D, V60I, S68G, T69C, K103R, K122E, K126R, I135IT, K173N, T200A, Q207E, R211K, V245E, T286A, I329LB
 N8B0MDHGISN8B0MDHGISKC169354NoneNone  E40D, K103KR, K122E, I142V, S162C, V179T, R211K, V261VI, T286A, I293V, P294T, E297A, S322T, G333GE, Q334HB
 O000M69GU4O000M69GU4KC169402NoneNone  V35T, E40D, V60I, D86E, K102Q, D177G, G196E, Q207E, A272S, T286A, I293V, E297A, I309IVB
 O100MD5IWHO100MD5IWHKC169451NoneNoneD67H M16L, E40D, T58P, K122E, D123E, I142V, V179VI, Q197E, T200A, E204K, Q207E, I293V, Q330PB
 OB00MF4VT7OB00MF4VT7KC169477NoneNone K103NV35I, E40D, V60I, K122E, D123DN, I142IT, I178IM, I195L, Q197E, T200A, Q207G, R211K, A272P, K277KR, T286A, I293V, V317A, Q334RB
 P000ML0MJOP000ML0MJOKC169529NoneNone  V35T, E40D, K122E, S162C, E169D, Q207E, R211K, A272S, P294A, L295LM, E312T, D324E, Q334LB
 Q2DEMD1NSTQ2DEMD1NSTKC169605NoneNone  E6ED, V35M, T39E, E40D, A98S, D123E, I135R, N175Y, P176PS, I178M, T200K, K201R, I202IV, T286A, A288S, K311KR, P321PS, Q334EB
 V200M91LIUV200M91LIUKC169713NoneNone  V35T, T39TA, E40D, V60I, A98S, D123E, I135T, Q174K, D177E, G196E, T200TA, Q207E, R211K, K249KQ, D250DE, A272A*GS, T286TA, P294QB
 G000M83RTSG000M83RTSKC168850NoneNone  V35T, E40D, V60I, A98Q, D121H, K122E, I135T, D177E, T200M, F214L, D250DE, A272P, I293V, P294PA, E297AB
 G000MEEPSYG000MEEPSYKC168856NoneNone  V35T, E40D, K49R, V60I, D121H, K122E, I135T, D177E, T200M, F214L, A272P, T286A, A288S, V292I, E297AB
 GC00F9BHRQGC00F9BHRQKC168884NoneNone  V35AT, E40D, K103R, D121H, K122E, I135T, S162C, T200IMV, F214L, A272P, K277R, K281R, T286A, E297AB
 GC00M6A9RRGC00M6A9RRKC168885NoneNone  V35AT, E40D, K103R, D121H, K122E, I135T, S162C, T200IMV, F214L, A272P, K277R, K281R, T286A, E297AB
 J000MF0MUFJ000MF0MUFKC168981NoneNone  E28A, V35T, T39A, E40D, K64KR, F87L, I135V, R211K, K275R, L283I, A288T, I293V, E297K, K311R, S322LB
Delwart (2012)476-8919-8476-8919-8JN214971NoneNone V179DE40D, K49R, A98S, E194N, G196E, F214L, V245K, D250E, A288S, I293V, E297QB
 477-4091-6477-4091-6JN214991NoneNone  V35T, T39A, E40D, R83K, T165I, Q174E, Q207E, R211K, V245E, A272P, K277R, T286A, I293VB
 477-5324-0477-5324-0JN214994NoneNone  V35I, E40D, I135T, I142T, E169D, G196E, F214L, V245E, S251N, I293VB
 477-4271-4477-4271-4JN215132NoneNone  V35M, T39A, E40D, R83K, V106VI, I135L, S162Y, G196E, R211E, V245K, V276I, A288S, I293V, E297KB
 478-9997-9478-9997-9JN215182NoneNone  E40D, K49R, K103R, I135T, K173Q, F214L, V245K, P247A, D250E, A272P, K277R, T286A, E297KB
Frange (2012)330426DHU330426DHUJQ291815NoneNone  E40D, A98S, I135V, F171Y, Q197K, T200I, R211KB
 940134FWV940134FWVJQ292227NoneNone  E40D, V60I, D121Y, K122E, I135T, I142V, S162A, T200A, E204D, Q207E, V245MB
 750409KMP750409KMPJQ292559NoneNone  V35T, T39K, E40D, K49R, D123E, I135T, T165I, Q174H, G196R, I202V, R211K, F214LB
 750820BMZ750820BMZJQ292560NoneNone  V35T, T39K, E40D, K49R, D123E, I135T, T165I, Q174H, G196R, I202V, R211K, F214L, V245Q, E248DB
Machado (2012)CUPL0913CUPL0913HQ655346NoneNone  K20R, V35T, E40D, V60I, V111E, K122P, I135V, I142V, T165I, Q174E, D177E, I178V, G196E, K201I, E204K, Q207G, R211K, F214LB
 CUPL0916CUPL0916HQ655349NoneNone  V35A, E40D, N54NI, V60I, K122E, D123S, E169D, D177E, T200A, Q207EB
 CUPL0921CUPL0921HQ655354NoneNone  P9S, V35T, E40D, K49R, D123E, E169D, D177E, I178L, I202V, E204N, Q207E, R211KB
 CUPL0937CUPL0937HQ655370NoneNone  K30T, I31P, V35T, E40D, V60I, K122P, I142V, T165I, Q174E, D177E, I178V, G196E, K201I, E204K, Q207G, R211K, F214LB
 CUPL0940CUPL0940HQ655373NoneNone  V35I, E40D, V60I, K122E, D123S, I135R, E169D, D177E, T200A, Q207E, K238R, V241EB
 CUPL1005CUPL1005HQ655382NoneNone  V35T, E40D, V60I, K122E, D123S, E169D, D177E, Q207E, F214L, K238RB
 CUPL1007CUPL1007HQ655384NoneNone  E6D, V8I, V21I, V35T, T39A, E40D, K49R, V60I, S68G, K122E, D123N, I135V, T139A, E169D, D177E, Q207E, K238KR, P243TB
 CUPL1015CUPL1015HQ655392NoneNone K103SV35A, E40D, E44K, V60I, D76N, K122E, D123S, T139K, E169D, D177E, T200A, Q207GB
 CUPL1054CUPL1054JN000026NoneNoneD67H K13R, V35T, I37N, E40D, K49R, E53D, V60I, E169D, D177E, T200A, Q207G, R211K, F214L, K238R, W239R, Q242KB
 CUPL1071CUPL1071JN000043NoneNone  E6K, K20R, V35T, E40D, V60I, K122P, I135V, I142V, T165I, Q174E, D177E, I178V, G196E, T200A, K201I, E204K, Q207G, R211K, F214L, V245Q, A272S, T286A, P294Q, I326V, Q334D, G335D, R356K, M357R, R358K, G359S, T369V, A371V, I375V, A376SB
 CUPL1086CUPL1086JN000058NoneNone  S3N, P4S, I5V, E6K, V8L, K20R, V35T, E40D, V60I, K82R, K122P, I135V, I142V, T165I, Q174E, D177E, I178V, G196E, K201I, E204K, Q207G, R211K, F214L, V245Q, Y271F, A272P, T286A, P294Q, I326V, Q334H, G335D, R356K, M357R, R358K, G359S, T369V, A371V, I375V, A376SB
 CUPL1106CUPL1106JX194185NoneNone  V35T, T39A, E40D, K122E, S162C, D177E, R211KB
 CUPL1129CUPL1129JX194208NoneNone  V35T, E40D, S48T, V60I, K122P, I142V, T165I, Q174E, D177E, I178V, T200I, K201V, E204K, Q207E, R211K, F214LB
 CUPL1131CUPL1131JX194210NoneNone K103NK30E, V35T, E40D, V60I, K122P, D123E, I135L, I142F, I178L, T200A, E203D, R211K, V245Q, D250E, A272P, T286A, E297R, L301I, I329V, Q334E, M357T, R358K, A376T, K385RB
 CUPL1152CUPL1152JX194231NoneNone  V35T, E40D, V60I, K122P, I135V, I142V, T165I, Q174E, D177E, I178V, G196E, K201I, E204K, Q207E, R211K, F214L, V245Q, Y271F, A272P, T286A, P294Q, I326V, Q334H, G335D, R356K, M357R, R358K, G359S, T369V, A371V, I375V, A376S, T386IB
 CUPL1157CUPL1157JX194236NoneNone  V21I, V35T, T39A, E40D, K122E, S162C, D177E, I178M, R211KB
Mollan (2012)MK101MK101w0 NoneNone  E6D, V8I, V35T, E40D, K49R, K102Q, K122E, D123DE, I135T, E169D, T200TI, I202V, R211K, S251C, A272P, K275R, T286A, I293V, P294T, E297AB
Ragonnet-Cronin (2012)A05_044A05_044JX014655NoneNone  E40D, S48T, D121H, K122E, S162A, D177E, G196E, R211G, A272P, K277R, I293V, E297AB
 B07_382B07_382JX014942NoneNone  V35T, T39TS, E40D, K101R, I135R, S162C, R211E, A272P, I293V, E297AVB
Ragonnet-Cronin (2012)PHAC07_325PHAC07_325JQ674786NoneNone  V35T, E40D, E44EK, E53EK, K101R, I135R, S162C, E194EK, R211E, A272P, I293V, E297AVB
 PHAC08_169PHAC08_169JQ674843NoneNone  E40D, S48T, D121H, K122E, S162A, D177E, G196E, Q197K, K201KR, R211G, V245K, A272P, K277KR, I293V, E297A, R307KB
 PHAC07_227PHAC07_227JQ674954NoneNone  E40D, S48T, D121H, K122E, S162A, D177E, G196E, R211G, V245E, A272P, I293IV, E297AV, E312EVB
 PHAC07_287PHAC07_287JQ674977NoneNone  V35T, T39A, E40D, D123E, I142V, T165TI, D177E, T200A, R211RK, F214FL, A272P, K277R, L283I, V292I, I293V, L295F, E297QRB
 PHAC07_290PHAC07_290JQ674978NoneNone  E40D, S48T, D121H, K122E, S162A, D177E, G196E, R211G, V245EK, A272P, K277R, I293V, E297A, E312VB
 PHAC07_361PHAC07_361JQ675016NoneNone  V35T, T39A, E40D, D123E, I142V, T165I, D177E, T200A, I202V, R211K, A272P, K277R, L283I, V292I, I293V, L295F, E297QB
 PHAC08_067PHAC08_067JQ675058NoneNone  E40D, S48T, D121H, K122E, S162A, D177E, G196E, R211G, V245K, A272P, K277R, I293V, E297A, A304E, E312EVB
 PHAC08_070PHAC08_070JQ675061NoneNone  V35T, E40D, K101R, I135R, S162CY, R211E, A272P, I293V, E297VB
 PHAC08_216PHAC08_216JQ675135NoneNone  E40D, S48T, D121H, K122E, I142T, S162A, D177E, G196E, E204Q, R211G, V245K, A272P, K277R, A288S, I293V, E297AB
 PHAC09_049PHAC09_049JQ675211NoneNone  V35T, E40D, V60I, K64R, K122E, D123E, T200I, V245Q, A272P, K277R, T286A, I293V, E297AB
 PHAC09_119PHAC09_119JQ675247NoneNone  V35T, T39A, E40D, D123E, I142V, D177E, T200A, I202V, R211EK, P243PL, A272P, K277R, L283I, V292I, I293V, L295LF, E297QB
 PHAC09_168PHAC09_168JQ675264NoneNone  V35T, T39A, E40D, D123E, I135IATV, I142V, T165I, D177E, T200A, I202V, E203EK, R211K, A272P, K277R, L283I, A288AG, V292I, I293V, L295F, E297QB
 PHAC09_183PHAC09_183JQ675270NoneNone  V35T, E40D, A98AS, K101R, I135R, S162C, R211E, A272P, I293V, E297VB
Soria (2012)27-1pla27-1plaJF690131NoneNone  V35I, E40D, K122E, D123S, I135T, T200A, F214LB
Antoniadou (2013)GR024GR024KF671859NoneNone  E40D, K102KEGR, K122KE, I135IT, S162H, Q174N, D177E, G196E, R211TB
 GR141GR141KF671948NoneNone  E40D, K102KR, K104R, K122KE, S162H, Q174N, D177E, G196E, R211AT, V245EB
 GR048GR048KF671871NoneNone  E40D, V90VI, K102R, S105SA, K122KPQT, D123DE, I135IT, S162HY, K173E, Q174N, V179I, G196GE, Q207QE, R211RT, V245VEB
 GR080GR080KF671894NoneNone  E40D, I135IT, S162H, Q174K, D177E, G196E, R211KB
 GR133GR133KF671940NoneNone  E40D, S162H, Q174N, D177E, G196E, R211TB
 GR055GR055KF671876NoneNone  E40D, S162H, E169D, Q174K, D177E, G196E, R211KB
 GR076GR076KF671892NoneNone  E40D, S162H, Q174K, D177E, G196E, R211KB
 GR035GR035KF671865NoneNone  E40D, K102R, K104R, S162H, Q174N, D177E, G196AE, R199RS, R211T, V245EB
Bila (2013)MZAng16HIV-1KF927400NoneNone  E6D, K20R, V35T, T39A, E40D, S48T, K49R, K122E, K173A, D177E, Q207EB
Chow (2013)MY1MR851MY1MR851KC478048NoneNone  V35I, E40D, D86E, I135V, S162C, I202V, K238R, V245E, K277R, T286VB
Ferreira (2013)BR09SP96BR09SP96HM534079NoneNone  V8I, K20R, K32R, V35T, T39A, E40D, D123DE, I135T, S162Y, K166R, I202V, Q207EB
 BR09SP348BR09SP348HM534175NoneNone  K20R, V35T, E40D, V60I, V118I, D123E, S162D, P176Q, Y183YC, Q197K, R211K, F214LB
Frentz (2013)EHR-00651EHR-00651JX299546NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, E40D, R83K, I135IV, E138EA, S162C, T200A, R211K, L228QB
 EHR-09436EHR-09436JX299687NoneNone  V35L, E36N, I37F, E40D, K122P, R125RW, I135T, I142V, S162Y, R211KB
 EHR-40586EHR-40586JX300226NoneNone  E40D, V60I, D121H, S162CY, D177DN, I178L, V245KB
 EHR-78361EHR-78361JX300889NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, E40D, K64R, K122E, D123K, T165I, G196E, T200A, I202V, E204DB
 EHR-99711EHR-99711JX301160NoneNone  V35VI, E40D, K166R, I178M, Q207E, R211KB
Hawke (2013)1451291614512916KC237939NoneNone  V35T, T39TA, E40D, K104R, K122E, D123N, I135T, D177E, I202V, V245MB
Heipertz (2013)306350_RT306350_RTJX863951NoneNone  V35M, E36D, E40D, I135V, I178M, R211K, V245M, T286A, I293V, E297K, T403IB
 306403_RT306403_RTJX863955NoneNone K103NE6D, V35T, T39A, E40D, D123E, D177E, V179I, R211K, F214L, E233EK, V245M, K277R, R284K, I293V, P294Q, M357T, A376T, T377N, V381I, T397TA, A400T, E404DB
Holguin (2013)ES84ES84JX466959NoneNone  V35T, E40D, D123E, D177E, T200A, E204ED, R211K, A272P, E291D, E297A, S322A, I329LB
 ES101ES101JX466972NoneNone  V35T, E40D, D123E, D177E, T200A, E204D, R211K, A272P, E291D, E297A, I329LB
 ES102ES102JX466973NoneNone  V35T, E40D, D123E, D177E, T200A, R211K, K238E, A272P, E291D, E297A, S322AB
 ES105ES105JX466975NoneNone  V35T, E40D, D123E, D177E, T200A, E204D, R211K, A272P, E291D, E297A, S322A, I329LB
 ES106ES106JX466976NoneNone  V35T, E40D, D123E, D177E, T200A, R211K, A272P, E291D, E297A, S322A, I329LB
Kiertiburanakul (2013)R41040R41040KC970928NoneNone  V35T, E40D, V60I, D123E, K166R, D177E, I178M, Q207R, R211K, W212G, K259EB
 R74179R74179KC791398NoneNone  E40D, K122E, I135V, S162C, E169D, D177DE, I178M, T200A, E203D, R211RKQB
 R72177R72177KC857162NoneNone  E40D, K122E, D177DE, I178M, Q207E, V245EB
Lunar (2013)pt7418694470308GQ400283NoneNone Y181CV35A, T39A, E40D, D123E, I135T, T200A, I202V, R211K, D250E, A272P, V292I, R307K, K311R, I329V, Q334EB
Ong (2013)08MYKL04408MYKL044KC181217NoneNone  E40D, K122E, S162C, K238R, V245EB
Smolen-Dzirba (2013)WJK11WJK11JF837548NoneNone  V35T, E40D, V60I, G112GE, D121H, I135T, S162Y, D177N, I178L, V245KB
 AJK10AJK10JF837547NoneNone  V35T, E40D, V60I, D121H, I135T, S162C, D177N, I178L, V245KB
 APS7199APS7199JF837588NoneNone  E28A, K32Q, V35I, E40D, S68G, K122P, K166R, I178L, T200E, R211K, E248Q, K249QB
Meixenberger (2014)10-0102910-01029KJ771243NoneNone  V21I, V35M, T39A, E40D, R83K, I135R, S162C, D177E, I178M, Q207E, R211A, V245E, S251H, A272P, K277RB
 09-0146409-01464KJ771000NoneNone  V35T, T39A, E40D, D121H, K122E, D123DG, F171Y, K173E, Q174R, D177E, R211K, A272P, V276VI, K277KRB
 07-0035407-00354KJ770413NoneNone  K20R, V35T, T39A, E40D, K102KR, D123EG, T165IV, K173R, I178L, G196E, T200A, E204N, Q207E, R211K, F214L, V245M, A272P, V276I, K281R, L283I, T286AB
Stanojevic (2014)RS0518RS0518KF362128NoneNone K103NV35T, T39A, E40D, D123E, I135T, I142T, I178L, V179I, T200A, I202V, R211KB
 RS0440RS0440KF157461NoneNone  V35I, E40D, S48E, R78RS, I135L, T139S, K173E, I202V, E204KB
 RS0513RS0513KF157481NoneNone K103NV35T, T39A, E40D, K102R, D123E, I135T, I142T, I178L, V179I, T200A, I202V, R211KB
 RS0041RS0041KF157420NoneNone  V35T, T39A, E40D, V90I, D123E, I135IATV, I178L, T200A, I202V, R211KB
 RS0574RS0574KF157503NoneNone  E6D, V35I, E40D, D123E, I135L, K173EB
 RS0320RS0320KF157439NoneNone  I31IK, V35T, T39A, E40D, V90I, D123E, I135T, R172RK, I178IL, I202V, R206RK, R211KB
 RS0104RS0104KF157422NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39A, E40D, S68G, G99R, K122E, D123E, I135T, I195IV, T200A, I202V, E204ED, R211KB
 RS0564RS0564KF157501NoneNone  V35I, E40D, S48E, I135L, T139S, K173EB
 RS0573RS0573KF157502NoneNone  E6D, V35I, E40D, D123E, I135L, K173EB
 RS0526RS0526KF157487NoneNone  V35T, T39A, E40D, R83K, K102Q, K122E, D177E, I178L, T200K, I202V, R211GB
 R0148R0148KF157505NoneNone  V35T, T39A, E40D, K122KE, D123E, I135R, K173*E, N175H, P176S, T200A, I202V, R211KB
 RS0404RS0404KF157452NoneNone  K13N, M16R, D17E, K20R, K22N, V35T, E36K, T39A, E40D, T69I, K102R, D121H, K122E, E169D, D177E, I178L, I195V, T200A, I202V, R211KB
 RS0415RS0415KF157455NoneNone  K20R, V35T, T39TA, E40D, K102Q, D123E, I135RT, P176S, T200A, I202V, R211KB