<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation G333D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Hammer (1997)ACTG320_273273 AZT, DDINoneD67N, K70R, T215Y V118I, K122E, I135T, T165I, Q174L, I202V, Q207E, R211RG, F214L, V245T, A272P, I293V, E298EK, K311R, I329V, G333D, A360T, K390R, A400T, K431T, L452S, G462E, R463D, Q464K, K465R, V466F, S468PB
 ACTG320_485485 AZT, DDINoneM41L, T215Y K49R, K166I, E203ED, E204D, R211RK, V245M, A272P, K277R, T286A, I293V, D324DE, G333D, Q334QH, R356K, A360AT, K366R, A371AV, A376T, A400T, L452S, S468P, T470TKPQ, H483HQB
 ACTG320_867867 AZT, DDINone  V35VI, R83K, V90VI, R211K, V245I, D250E, A272P, K275R, K277R, Q278H, E297K, G333D, Q334H, A376T, K390R, A400T, V435E, N447S, D460N, S468PB
Coakley (2000)EC22EC22F D4T, DDINone  V60I, R83K, D123E, S162C, D177E, T200A, V245E, K277R, Q278H, T286A, I293V, E297K, G333D, E370D, T377K, V381I, K390R, V435I, D460N, L469I, L491SB
 EC36EC36F D4T, DDINoneM41L, T215F I178M, V245M, A272P, K277R, I293V, E297K, G333D, R356K, S468P, H483Y, E492D, Q509HB
Bacheler (2001)DMP003-6903-69000AAF349355NRTINoneD67DN, K70R, K219Q K122E, I178M, G196E, R211K, A272P, K277R, I293V, G333D, R358K, K390R, A400TB
Riddler (2008)RG91625RG91625w23 TDF, 3TCNone  K64R, K104R, K122E, D123E, I135V, T139A, K173E, T200A, I202V, E248DN, K249KQ, A272P, I293V, G333D, Q334H, M357T, A376S, T377L, K390RB
Melo (2012)0063SP0063SPJF804806NRTINone Y181CR83K, V90I, K104R, D123E, S162N, Q174H, I195L, R211K, L228R, A272P, I293V, E297R, D324E, L325V, I329L, G333D, A360T, T386I, K390R, E399D, A400T, K431T, I434V, V435A, A446S, L452Q, V466A, V467I, D471E, Q480H, H483L, L484I, L491S, S519N, Q524E, A534S, V559IB