<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation T215V
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 11
Patients 20
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Orlandi (1998)PO-Pt21Orl21-W220AF056677AZTNoneD67N, K70R, T215V, K219Q T39A, D123EB
  Orl21-W272AF056678AZTNoneD67N, K70R, T215V, K219Q T39A, D123EB
  Orl21-W300AF056679AZTNoneD67N, K70R, T215V, K219Q T39A, D123EB
Zolopa (1999)CA1170CA2657AF088118AZT, DDI, 3TC, D4T, DDCNoneD67N, K70R, M184V, T215V, K219E T69N, I135T, T200A, Q207EB
Bacheler (2000)LB4-P103P103-0 AZT, 3TCNoneD67N, K70R, M184V, T215V, K219Q V35I, K104N, I135L, K166RB
 LB4-P139P139-0 AZT, 3TCNoneD67N, K70R, M184V, T215V, K219Q K20R, K64N, T69N, V90I, K122E, R211K, D218EB
Balotta (2000)CB-210CB-210AF252060DDC, AZT, D4T, 3TCNoneD67N, K70R, T215V, K219Q T69N, V90I, D110DN, D123E, E138CY, T139TA, G141R, I180VB
Gonzales (2001)CA1809CA4854AY030724AZT, 3TC, D4TNoneD67N, K70R, M184V, T215V, K219Q K43KE, T69N, K103R, V118I, I135L, G196E, R211K, F214LB
 CA3975CA9221AY030974AZT, DDC, 3TCNoneD67N, T69DN, K70R, M184V, T215V, K219Q G196E, Q207H, R211K, F214LB
 CA4104CA9406AY031095AZT, DDI, DDC, D4T, 3TCNoneD67N, K70R, M184V, T215V, K219Q V35M, T39TA, T69N, I135M, I178M, G196E, R211K, K281R, A288S, I293VB
 CA4902CA12010AY0315423TC, AZTNoneD67N, K70R, M184V, T215V, K219Q I135M, Q174H, Q207E, R211K, F214FL, A272P, A288T, I293V, E297K, A304GB
 CA5153CA12448AY031720DDI, AZT, D4T, 3TCNoneD67N, T69D, K70R, M184V, T215V, K219Q V60I, V118I, I135T, Q174H, T200TA, I202V, Q207R, R211E, F214L, L228Q, I293V, A304G, I329L, M357MR, A360T, K390R, A400T, L469I, L491S, K540TB
 CA5752CA14183AY032142AZT, DDI, D4T, 3TCNoneD67N, K70R, M184V, T215V, K219Q V35M, V60I, I135IM, R211H, T216TP, F227FS, V245M, D250EB
Shulman (2001)302-270048270048 AZTNoneD67N, K70R, T215V, K219Q K20R, V60I, T69N, K104N, T200A, I202V, Q207AE, R211RK, T286A, I293VB
Cuevas (2002)CU21CU21AF425402AZT, 3TCNoneD67N, K70R, T215V, K219Q V60I, T69N, K104N, D123E, I135T, D177E, R211KB
Tural (2002)94609460 AZT, 3TC, D4T, DDINoneD67N, K70R, T215V, K219Q K20R, K43E, K49R, V60I, T69N, D123E, S162N, D177E, R211K, F214L, D218EB
 881302881302 DDC, AZT, 3TC, D4TNoneA62V, D67N, K70R, M184V, T215V, K219Q I50V, P119A, F124L, I135V, T200AB
Roge (2003)ehh6ehh6-F2AY222063ABC, D4T, DDINoneD67N, K70R, V75T, T215V, K219Q K64Y, D123E, D177E, G196E, T200I, H208HY, R211K, D218EB
Rhee (2005)CA1170CA11998AY800798AZT, DDI, 3TC, D4T, DDCNoneD67N, K70R, M184V, T215V, K219E T69N, I135T, T200A, Q207E, E297KB
 CA5175CA37859AY801506AZT, 3TC, DDINoneD67N, K70R, T215V, K219Q V35VI, V60I, T69N, D121H, K122E, I135T, I178M, T200A, R211T, D218E, K277R, Q278E, I293V, E297RB
 CA6418CA34664AY801650AZT, 3TC, D4T, DDI, ABCNoneD67N, K70R, L74I, V75S, M184V, T215V, K219Q K11KR, K64Y, K122E, N175Y, T200A, I202V, Q207E, L228H, A272P, I293V, S322T, Q334E, M357S, T369TA, K385KR, T386TI, K390R, K395R, A400T, K454R, D460N, R461K, S468T, H483Y, Q509L, K530KR, Q547HNB
 SWC-85468546-2041 AZT, DDC, 3TC, D4TNoneK70R, M184V, T215V, K219Q K64H, T69N, A98S, V118I, V179I, T200E, F214LB
  8546-2958 AZT, DDC, 3TC, D4TNoneK70R, M184MV, T215V, K219Q K64H, T69N, A98S, V118I, V179I, T200E, F214LB
  8546-3393 AZT, DDC, 3TC, D4TNoneD67G, T215V, K219Q V35I, K64H, T69N, A98S, V118I, V179T, T200E, R211K, F214L, S251NB
  8546-3573 AZT, DDC, 3TC, D4TNoneD67DG, T69DN, K70R, T215V, K219Q V35VI, K64H, A98S, V118I, K122KE, V179IT, T200E, R211RK, F214LB
  8546-3725 AZT, DDC, 3TC, D4TNoneD67DG, T69DN, K70R, T215V, K219Q V35VI, K64H, A98S, V118I, K122KE, V179IT, T200E, F214LB
von Wyl (2007)494821915EF449891NRTINoneM184V, T215V, K219QA98GK20R, V21VI, V60I, V118I, K122E, I135T, I202V, R211K, F214LB