<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation T215S
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 14
Patients 21
Isolates 29
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ruiz (1996)JCS-C27C27W24Z99321DDC, AZT, 3TCNoneD67N, K70R, M184V, T215S, K219Q K64H, T69N, K122P, D177E, Q207E, L210G, P217Q, L228HB
Venturi (1999)GV-3Vent3W24AF169047AZT, DDINoneK70R, T215S R83K, D123E, I135T, Y144*, G196EB
 GV-11Vent11BAF169062AZTNoneD67N, K70R, T215S, K219Q G51A, T69N, V106I, D123E, I135IT, Y144Y*, F214LB
  Vent11W24AF169063AZT, DDINoneD67N, K70R, T215S, K219Q K43R, T69N, V106I, V118M, D123E, I135T, Y144*, F214LB
Si-Mohamed (2000)AS_BONAS_BONAF199321AZTNoneT215S K49R, R83K, I202VB
Delgado (2001)ED_V7ED_V7AY016917AZT, 3TCNoneM184V, T215S S68G, K122E, I135T, A158S, I178M, T200E, R211K, V245MTB
Gonzales (2001)CA4330CA10521AY031194AZT, DDI, 3TCNoneM41L, D67N, T69D, K70R, M184V, T215S, K219Q D17DG, K20R, P25PA, V35L, V60I, K103R, V118I, K122E, S134SC, K173E, Q207E, F214L, L228H, K277R, A288T, I293V, E297KB
 CA5207CA12511AY031770AZT, 3TCNoneM184V, T215S V21I, D123E, I135T, V179I, T200E, F214L, K275K*, Q278QEB
Naugler (2002)WES-10HIV10BLAF422707AZTNoneK70R, V75I, T215S, K219Q K64R, D123E, I142T, D177E, I178M, R211K, F214LB
  HIV10ESAF422732AZT, DDINoneK70R, V75I, T215S, K219Q K64R, D123E, I142T, D177E, I178M, Q207P, R211K, F214LB
 WES-11HIV11BLAF422708AZTNoneM41L, L210W, T215S V35L, V60G, A62P, V106I, I202V, R211KB
  HIV11ESAF422733AZT, DDINoneM41L, L210W, T215SK103NV35L, E42V, V60G, A62P, L100V, V106I, I202V, R211KB
Dumans (2004)259259AY390161AZT, DDINoneT215S K122E, I135T, S162C, D177E, S191F, G196E, Q207HB
 260260AY390162AZT, DDINoneM41L, L210W, T215SK103NV118I, D121Y, K122E, D123E, I135T, S162C, D177E, G196E, Q207H, R211KB
Kuritzkes (2004)KDR_pat56A0062AY527879D4T, 3TCNoneM41L, M184V, L210W, T215S K122E, T200A, Q207E, R211KB
  A0063AY527880D4T, 3TCNoneM41L, M184V, L210W, T215S K122E, T200A, Q207E, R211KB
Machado (2004)con15con15AY313430AZT, DDINoneT215S K64R, K122T, I135T, E138A, I142V, D177E, I178V, G196R, T200AB
Montes (2004)MB_patAVO01_AVO720AJ577732DDC, AZT, 3TC, D4TNoneA62V, M184I, L210W, T215SA98GR83K, I135V, S162C, T165V, I202VB
Holguin (2005)SP_SK2SP_SK2AF466719AZT, 3TCNoneL210W, T215S V60I, R83K, I94V, A98S, I135V, E138AB
Rhee (2005)CA8441CA21202AY802020D4T, 3TCNoneT215SA98GS68G, D123E, I178LV, V179I, E204EK, Q207E, R211K, A272X, Q278QH, T286A, E291D, P294QB
 CA9749CA23924AY8020983TC, D4TNoneD67N, M184MV, T215S, K219E K20R, S68SDGN, D123N, I135T, I142T, S162A, V179VI, R211G, K277R, R284K, I293V, E297K, I326V, M357T, A360T, A376T, T386I, K390R, A400T, S468P, L469I, H483N, G490E, Q509HB
 CA9963CA34259AY802215AZT, 3TCNoneM41L, L210W, T215S V35M, T39A, R83K, K122E, D123N, T139A, Q174K, D177E, G196E, V245M, I293V, P294Q, E297K, R358K, V435I, S468PB
  CA24658AY802216AZT, 3TCNoneM41L, L210W, T215S V35M, T39A, R83K, K122E, D123N, T139A, D177E, G196E, V245M, I293V, P294Q, E297K, A304E, E308Q, K311R, M357K, A376T, T377L, K385R, K390R, E399D, A400T, V435I, D460N, H483Y, G490E, Q509T, K512Q, L517I, S519NB
  CA34403AY802217AZT, 3TC, ABCNoneM41L, L210W, T215S V35M, T39A, R83K, K122E, D123N, T139A, Q174K, D177E, G196E, E204EK, V245M, I293V, P294Q, E297KB
 CA17600CA41441AY802530AZT, 3TC, DDINoneM41L, T215S V60I, D123E, G196E, I202IV, R211K, S251I, A272S, K281KR, I293IV, E297KB
  CA48566AY802531AZT, 3TC, DDI, ABC, TDFNoneM41L, T215S V60I, D123E, G196E, I202IV, R211K, K238KR, K249KQ, S251I, A272S, K281R, I293V, E297KB
  CA48568AY802532AZT, 3TC, DDI, ABC, TDFNoneM41L, T215S V60I, K122E, D123E, G196E, R211K, S251I, A272S, K281R, E297KB
von Wyl (2007)4662309EF449973NRTINoneM41L, M184V, T215S V60I, K122E, D123E, I132V, I135T, T165I, D177E, G196E, I202VB
Mollan (2012)MK204MK204w36 ABC, 3TCNoneL74LI, M184V, T215SK103NT39A, K122E, I135T, I142T, S162C, R172RK, T200A, Q207E, P294TB