<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation M184V
Rx RTI-naive
IncludeMixtures No
References 49
Patients 101
Isolates 103
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gonzales (2001)CA4425CA10636AY031279NoneNoneM184V E29D, V35T, V60I, R83K, G196E, T200TA, I202V, V245Q, A272P, K277RB
Perno (2001)PCF_Pat23PCF3776AF376699NoneNoneM184V K20R, K102Q, K122R, D123E, I135T, S162C, R211K, I293V, E297KB
Brindeiro (2003)BRC1537BRC1537AY213530NoneNoneM184V E6D, K49R, P119L, K122E, I135T, E169D, G196E, T200I, Q207K, R211AB
Gulick (2004)RG44RG44w0 NoneNoneM184V I37X, K102Q, K122E, I135V, S162C, D177DE, T200A, Q207E, R211K, V245XB
Yerly (2004)167GE98_167AY562471NoneNoneM184VK101E, G190AK49R, E53D, K122E, I135T, L168LPS, E169D, T200AB
Bernardin (2005)10581058-08AY331294NoneNoneM184V V35A, T39A, R83K, K122R, D123E, I135V, D177E, R211K, S251T, K277R, Q278H, K390R, A400S, E404D, Q524E, A534T, Q547KB
  1058-11AY331295NoneNoneM184V V35A, T39A, R83K, K122R, D123E, I135V, D177E, R211K, S251T, K277R, Q278H, K390R, A400S, E404D, Q524E, A534T, Q547KB
Escoto-Delgadillo (2005)18GDLEVV-RT_18GU291865NoneNoneV75A, M184VK103NK64R, F77S, V90F, P119PS, D123E, I135T, K166R, T200A, Q207D, R211RKB
Vazquez de Parga (2005)RU01009RU01009EU345724NoneNoneM184V V35I, A98S, K122Q, I135L, R172RK, D177E, I178M, E204A, Q207E, E248EK, T286A, E297AB
Jayaraman (2006)2-00-06342-00-0634 NoneNoneM184V S162C, T200AB
 2-01-01352-01-0135 NoneNoneM184V A98S, T139K, S162C, G196E, Q207E, R211K, F214L, L228Q, V245EB
Lama (2006)Pt40434043 NoneNoneM184VK101E, K103NT27S, E28K, T39S, D121Y, K122E, D177E, E203K, R211K, V245E, I293V, E297T, V317A, I329VB
Saad (2006)MDS_02UAKV17702UAKV177DQ055305NoneNoneM184V K32N, V35I, A98S, D123E, I135R, T200IB
Santos (2006)PA178PA178DQ343977NoneNoneM184VK103NA98S, I195L, T200AB
 PA227PA227DQ343995NoneNoneM184V K20R, I135T, Q174H, R211KB
 057RT057RTAY275790NoneNoneM184V D123E, S162C, K166R, D177N, T200A, L210S, F214LB
 B150RTB150RTDQ190952NoneNoneM184V V35I, R83K, I135T, Q197E, I202VB
 B025RTB025RTDQ190993NoneNoneM184V K82R, K122E, I142V, R211KB
 B042RTB042RTDQ190997NoneNoneM184V K122E, I135T, K173T, I178M, T200A, Q207N, R211KB
 DB104RTDB104RTDQ191037NoneNoneM184V K49R, V60I, K122E, I135L, D177E, W239X, E248QB
 PA136PA136DQ343966NoneNoneM184V I50V, A114V, K122E, D123E, I135T, T200A, I202VB
Valle-Bahena (2006)RT-54PROT-RT-54DQ150721NoneNoneM184V D123E, S162Q, D177E, A272P, I293V, P294S, W337M, G359S, A371V, K390R, A400T, V435LB
Zarandia (2006)MZ_03GEMZ01503GEMZ015DQ205272NoneNoneM184V V35I, K122Q, I135T, D177G, E194K, Q207EB
Brumme (2007)1086RT_1086EF369220NoneNoneM184V V35I, R83K, K122R, I135T, D177E, I178M, T200E, Q207H, R211KB
 1379PRRT_1379EF368689NoneNoneM184V I135L, T139TS, S162C, K173S, I178L, T200A, Q207K, R211M, A272P, V276I, K277R, L283I, I293V, E300ED, V317A, S322T, K390R, K395R, E399DB
Gatanaga (2007)C03-5555-5061-1C03-5555-5061-1AB640342NoneNoneM184V T7P, K20R, V35T, A98S, K122E, I178M, T200A, Q207E, P225SB
 C04-5555-5926-1C04-5555-5926-1AB640406NoneNoneM184V K32KR, V35I, I50IV, K122KE, I135L, S162C, T200TI, R211RKB
Gonsalez (2007)90HIV_90GU288716NoneNoneM184VK103N, P225HE6D, K11R, K101Q, I135T, I178M, T200I, R211K, L228N, V245MB
Holguin (2007)566846566846EF583181NoneNoneM184VK101KAET, K103KN, V106VAK49R, K102KR, I135L, K166R, E169D, I202V, R211K, F214L, V245L, A272P, K277R, T286A, I293V, K311R, G333E, Q334SB
 598842598842EF583228NoneNoneM184VV106M, V179DV35I, R83K, K122E, I178L, R211K, V245M, A272P, I293V, E297A, K311R, G333DB
Rios (2007)CH26MR_CH26EF193913NoneNoneM184V K122E, S134SI, K166R, R172RK, D177E, R211K, D250E, K277RB
Sanchez Onoro (2007)598842598842 NoneNoneM184VV106M, V179DV35I, R83K, K122E, I178L, R211K, V245M, A272P, I293V, E297A, K311R, G333DB
Chang (2008)TW8145TW8145DQ640278NoneNoneM184V V35L, K166KR, I178IM, Q207E, F214LB
 TW6335TW6335EU164874NoneNoneM184VV106A, G190GA, F227LV35M, S68SG, K122E, I178L, T200A, I202IV, Q207E, F214FLB
 TW8189TW8189EU164878NoneNoneM184VG190AT27TP, E28A, K122E, I135T, K166R, K173KE, F214L, V245IM, L246VB
 TW9570TW9570EU164898NoneNoneM184VV179EV35M, K43N, I135T, A158S, S162C, K166R, D177E, I178M, T200AB
 TW8023TW8023EU164912NoneNoneM184VV179DV35L, V60I, R83K, K103R, I135L, K173E, Q207EB
 TW1409aTW1409a NoneNoneM184VK103N, V108IV35L, R83K, K122E, I135L, Q207E, R211KB
Holguin (2008)05SP24-27995805SP24-279958EU255327NoneNoneM184V I135T, R211RK, F214X, V292I, I293V, I326IVB
 SP48-276330SP48-276330EU255351NoneNoneM184V A98S, D123E, I142V, A158S, I202X, R211KB
 SP53-290843SP53-290843EU255356NoneNoneM184VV106A, V179E, F227LV35I, R83K, K102R, I135T, G196E, T200I, Q207E, T286A, I293V, E297K, P313A, V317AB
 SP67-267814SP67-267814EU255370NoneNoneM184VK103N, P225HK20KR, V35X, A98X, K122E, I135L, S162C, T200A, V245K, I293V, I329V, Q336XB
 SP51-328859SP51-328859EU255424NoneNoneM184VK101E, G190AI37X, K49KR, I142IV, Q207EG, R211K, F214L, K277R, E297EK, I326V, I329VB
 SP60-339726SP60-339726EU255433NoneNoneM184VK103NK49KR, L74X, K104KR, Y115X, I135T, S162C, R211K, H221Y, V245EB
 SP21-0240626SP21-0240626EU342754NoneNoneM184V V35T, T39A, D123E, S162C, I178L, G196E, T200I, E204EK, R211K, A272P, T286A, A288S, E297K, D324EB
Lloyd (2008)CR04003HN_CR040EU312649NoneNoneM184VK103N, V108VIV60I, A98S, I135T, Q174E, I202V, R211M, V245E, A272P, I293VB
 CR04203HN_CR042EU312651NoneNoneM184VK103N, V108IK20R, I135T, S162C, Q174E, Q207R, F214L, H221Y, V245M, K249R, A272S, K277R, Q278E, I293V, E298A, E312KB
 CR09003HN_CR090EU312676NoneNoneM184VK103N, V108I, G190AK101Q, D123E, I135K, Q174K, T200I, R211S, V245M, A272T, K277R, T286A, I293VB
 CR09403HN_CR094EU312679NoneNoneM184VK103NK20R, V35I, D123E, I135L, Q174E, D177E, Q197R, R211K, V245M, S251R, K277R, T286A, V292I, I293V, E297AB
 CR16403HN_CR164EU312719NoneNoneM184VY181CV35I, D86E, D121Y, K122E, I135T, I142T, T165M, I178L, I195T, T200TA, F214FL, V245VM, A272P, V276I, L283I, I293V, E312TB
 CR00603HN_CR006EU312722NoneNoneM184VK103NV60I, A98S, I135T, Q174E, I202V, R211M, V245E, A272P, I293VB
 CR00903HN_CR009EU312723NoneNoneM184VK103N, P225HV60I, K101Q, I135T, I178M, T200A, V245Q, A272P, T286A, I293VB
 TX17003HN_TX170EU312908NoneNoneM184VY181CV35VA, D123E, I135R, A158AT, K173R, I202V, R211K, F214L, D250E, A272P, K277R, I293V, P294S, E297RB
Riddler (2008)60381535D_bsHM056607NoneNoneM184V K20R, K122A, I142T, K166KR, K173Q, I178L, V179VI, R211K, A272P, G273R, K275R, K277R, Q278H, T296TS, E297K, I329L, A376V, K390R, A400T, V417I, V435I, R461K, S519N, A554TB
Aghokeng (2009)CDL26CDL26GU191611NoneNoneM184VK101E, G190AK11N, V35T, T39R, K43E, D123N, K166R, D177E, V179I, T200A, Q207A, R211K, V245Q, E248D, K277R, T286A, A288G, V292I, I293V, P294T, E297R, S322K, D324E, I329L, G335D, R356K, M357K, G359S, V365I, K366R, A376S, K390R, A400T, T403MB
Brown (2009)CAS_1069_16_38764CAS_1069_16_38764FJ030648NoneNoneM184V R83K, I135T, S162Y, R211GB
Cuevas (2009)P1209P1209.1EU822600NoneNoneM184V P25PS, E29EQ, V60I, S68G, Q85QP, K122E, I135T, K173KE, Q174R, I178L, R211KB
 P0036P0036.1EU822773NoneNoneM184VK103NI135ILM, T200A, Q207T, R211KB
 P0556P0556.3EU822776NoneNoneM184V V60I, S68G, K122E, I135T, K173E, Q174R, I178L, R211KB
 P0755P0755.1EU822779NoneNoneM184V E36D, V60I, D76DN, A98S, K101Q, K122E, I135K, R143K, I178L, T200IB
de Sa-Filho (2009)5504255042PgrGQ294604NoneNoneM184VV108IK102Q, I135T, S162CB
Dumans (2009)202_05202_05FJ405102NoneNoneM184V K20R, K122E, I135T, R199S, T200R, R211K, V245KB
 84_0584_05FJ405115NoneNoneM184VK103NI135T, K173RB
Smith (2009)PI253US2000PI253 NoneNoneM184V E6D, T39A, D123E, I142V, S162C, R211Q, V245T, K275KQ, K277KR, V292I, I293VB
 PI322US2002PI322 NoneNoneM184V E6D, R211A, V245K, G273GR, T286A, I293VB
 PI328US2003PI328 NoneNoneM184V P4PL, K20R, R83K, V90I, K102KQ, I135V, S162CY, G196E, R211GB
 CR178US2006CR178 NoneNoneM184VK103NE28K, D123E, I135T, S162C, D177E, T200A, I202V, Y232H, V245E, I293V, P294QB
 CR207US2006CR207 NoneNoneM184VK103N, G190GA, P225PHV35I, S48E, K82KR, R83K, V90VI, K101KQ, K102Q, T200TA, R211K, A272AP, K281KR, R284K, I293V, P294PTB
 CR234US2006CR234 NoneNoneM184V A98S, D123E, I135IV, I142IT, Q174H, D177E, R211KQ, R284K, T286A, T296S, E297KB
 CR242US2006CR242 NoneNoneM184V K102R, T139K, D177E, I178M, V179I, R211K, F214FL, H235HR, V245E, T286A, A288AV, E291ED, I293IM, E297K, A304EB
Thomson (2009)SP_B_004RU_SP_B_004FJ009782NoneNoneM184V D123E, I142V, S162A, K166KR, D177E, R211K, F214L, V245T, A272P, K277R, T286TA, A288S, I293V, E297KB
Vercauteren (2009)pt15563993935960GQ399468NoneNoneM184V I50V, K122E, I142V, T200A, F214L, V245TB
 pt8787935314489GQ400146NoneNoneM184VK103N, K238TE28A, V35T, V60I, K122E, I135V, S162C, F214L, V245K, A272P, I293V, E297A, D324E, I326VB
Wang (2009)CR0222XCR0222XFJ469709NoneNoneM184V, N348I V21I, I135L, V245E, E248N, V276I, Q278E, L283I, I293V, E298A, R356K, A376T, K390R, T403M, V417I, E432D, A446S, R461K, K527N, A554SB
 L861PL861PFJ469748NoneNoneM184V V60I, R83K, K102R, I135V, R211K, I244V, D250V, A272P, E297Q, S322T, I329L, A360V, A400T, V435I, D460N, R461K, K465R, V467I, L469I, H483N, L491P, A554SB
Bonura (2010)865_77865_77GU969490NoneNoneM184VK103N, Y188LR83K, K102KR, K122E, R211K, E224D, A272P, I329VB
Brennan (2010)ARC-A240ARC-A240GU565680NoneNoneM184V K20R, I37IS, E44EK, K49R, K122E, D123NS, E138A, I142IV, D177E, V179I, F214L, P243S, I293V, E297EK, D320DNB
 ARC-A242ARC-A242GU565681NoneNoneM184VK103NK11R, R83K, I142V, S162A, D192DN, I202V, L210S, R211K, A272P, K311KR, D324E, I329L, Q334YB
Yebra (2010)32435006SP324350FJ481806NoneNoneM184V K49R, R83K, V90VI, L120S, S134SG, S162X, T165TI, E169D, G196EB
Aulicino (2011)3128-I2853128-I285HQ158258NoneNoneM184V V35I, R83K, V118VI, K122EB
El Annaz (2011)26112611HQ393336NoneNoneM184V K102R, V118I, K122E, Q174E, T200A, Q207E, R211K, F214L, V245EB
Sanabani (2011)BR2018BR2018JN692449NoneNoneM184VK103ND123E, I135M, K166R, V189I, T200A, A272P, K281R, P294T, E297K, V317A, Q334N, Y342F, M357T, A376S, T377I, K390R, T397I, A400T, V435I, D460H, R461K, T470S, H483L, I506L, L517I, K527R, A554TB
Santos (2011)J63J63_PR_RTJN010450NoneNoneM184VK103NV35I, I142V, E169D, G196V, T200K, Q207E, R211KB
Truong (2011)0500109305001093JX073489NoneNoneM184V K49R, D123E, I135T, D177E, R211K, V245TB
Avila-Rios (2012)JFJ0MG0SRLJFJ0MG0SRLKC169131NoneNoneM184VY188LV106I, K122P, S162N, D177N, V189I, Y232H, K249Q, P294T, K311R, Q334EB
 CJ00MB2MQECJ00MB2MQEKC168228NoneNoneM184V V35M, D123E, K173N, Q174K, I178M, Q207E, R211K, A272P, P294Q, E312T, D324DEB
 VJ00MF5IUMVJ00MF5IUMKC169741NoneNoneM184V V35M, R83K, K122P, I135L, I142V, K166R, D177E, G196E, T200A, R211K, A272P, K277R, I293V, E297Q, L301I, D324DE, Q334LB
 J0JYMB5PR5J0JYMB5PR5KC169007NoneNoneV75L, M184VG190SK20R, E53D, V90I, K122P, A272S, I293V, P294S, E297K, D324E, I326LB
De Gascun (2012)IRL15220IRL15220JN622634NoneNoneM184VK103NR83K, V90VI, D123E, T200A, I202V, Q207K, R211KB
 IRL31721IRL31721JN622657NoneNoneM184VK103N, G190GA, P225HV60I, F77FS, Q197K, T200E, E204D, R211KB
Delwart (2012)476-8892-6476-8892-6JN214970NoneNoneM184VP225HV8I, T200A, K277RB
Machado (2012)CUPL0902CUPL0902HQ655335NoneNoneM184V K122P, I135R, S162C, R211KB
 CUPL1114CUPL1114JX194193NoneNoneM184VY181CK20R, K49R, A98S, D123E, I135T, E169D, D177E, I178L, Q207K, F214LB
 CUPL1119CUPL1119JX194198NoneNoneM184VY188LV35M, A98S, E138A, S162C, G196E, Q207D, R211KB
 CUPL1142CUPL1142JX194221NoneNoneM184VK101H, G190AV35I, E40D, V60I, S68G, K122E, D123S, I135T, E169D, D177E, V179I, Q207E, I244VB
Melikian (2012)CA75822CA162699 NoneNoneM184VV106M, V179DV35VI, D123E, I135T, F214L, Y232H, I244V, T286A, I293VB
Murillo (2012)1139711397KC412769NoneNoneM184V K20KR, E28EA, V60I, D86E, I142V, S162H, D177E, I178IM, V245MB
 1201312013KC412787NoneNoneM184V V35M, T39A, K82R, R83K, V118I, D123E, I135T, S162G, D177E, R206RG, R211K, F214L, E248DB
Ragonnet-Cronin (2012)A05_063A05_063JX014667NoneNoneM184V E6D, I135IL, S162C, T200I, I274V, K277R, I293V, E297AB
 B07_181B07_181JX014919NoneNoneM184V S68N, I178M, T200A, R211K, V245K, S251I, I293V, E297KB
 D05_004D05_004JX015017NoneNoneM184VK101E, K103N, P225PHV10VL, E28K, V60I, I135T, S162C, T200A, I202V, Q207GR, R211K, L283LI, I293V, E312RB
Ragonnet-Cronin (2012)PHAC07_311PHAC07_311JQ674784NoneNoneM184VK103N, V108II135T, S162C, D192DN, G196E, H221Y, S251SI, K277R, I293V, E297AB
 PHAC09_039PHAC09_039JQ674897NoneNoneM184V V35I, K104R, I135K, K173E, Q207E, V245T, A272P, I274V, K277R, I293VB