<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation M184I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 12
Patients 22
Isolates 34
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Venturi (1999)GV-14Vent14W24AF169069AZT, DDCNoneM184I K103KR, D121N, D123E, W153*, G155R, K166R, G196R, I202VB
Balotta (2000)CB-5CB-5AF186770DDC, AZT, D4T, 3TCNoneM41L, T69S_SG, K70KR, M184I, L210W, T215Y S48T, D86DN, T107TP, D110DN, V118I, K122P, I195V, Q197R, T200EB
Baxter (2000)GART-G86GART-86 NRTI, 3TC, D4TNoneM41L, D67N, T69D, M184I, L210W, T215Y V21I, E44D, V118I, K122E, D123E, S162C, D177E, Q197K, T200A, E203K, H208Y, R211K, K223E, V245KB
 GART-G108GART-108 NRTI, 3TC, D4TNoneM41L, D67N, K70R, L74I, M184I, L210W, T215Y, K219Q K20R, V35L, K122E, A158S, E169D, T200I, R211K, D218EB
Falloon (2000)JF10JF10-(-)1wAF227723AZT, DDI, DDC, D4T, 3TC, PFANoneM41L, D67N, T69D, L74LI, V75T, M184I, L210W, T215C, K219RV108IV118I, K122E, I178M, G196E, E203K, R211E, F214XB
  JF10-12wAF227724AZT, DDI, DDC, D4T, 3TC, PFA, ABCNoneM41L, D67N, T69D, L74LI, V75T, M184I, L210W, T215C, K219RV108IV118I, K122E, I178M, G196E, E203K, R211EB
Katzenstein (2001)ACTG302_18931893RT_f1 AZT, DDI, 3TCNoneM41ML, A62V, D67E, K70R, F116Y, M184I, L210W, T215Y V35VI, T69S, R83RK, V90I, V118I, S162C, T165TI, R211S, L228H, A272P, K277R, R284RIB
Servais (2001)JS15JS96414AJ401757AZT, DDI, DDCNoneM41L, D67N, K70R, M184I, L210W, T215Y T39E, E44D, V118I, D123E, I135T, S162C, G196E, E203D, R211KB
  JS97051AJ401764AZT, DDI, DDC, 3TC, D4TNoneM41L, D67N, K70R, M184I, L210W, T215Y T39E, E44D, V118I, D123E, I135T, S162C, G196E, E203D, R211KB
  JS97359AJ401785AZT, DDI, DDC, 3TC, D4TNoneM41L, D67N, K70R, M184I, L210W, T215Y T39E, E44D, V118I, I135T, S162C, G196E, R211KB
  JS97498AJ401792AZT, DDI, DDC, 3TC, D4TNoneM41L, D67N, K70R, M184I, L210W, T215YG190AT39E, V118I, I135T, I142V, S162C, G196E, E203D, R211KB
 JS21JS97295AJ401782AZT, DDI, D4T, 3TCNoneT69S_SS, K70R, M184I, T215Y K64R, D123E, I142T, Q197E, R211K, F214W, D218H, I244LB
  JS98025AJ401795AZT, DDI, D4T, 3TCNoneA62V, T69S_SS, K70R, M184I, L210W, T215Y K64R, D123E, Q197E, E203K, R211K, F214W, D218H, I244LB
  JS98158AJ401805AZT, DDI, D4T, 3TCNoneA62V, T69S_SS, K70R, M184I, L210W, T215Y K64R, V118I, D123E, Q197E, E203K, R211K, F214W, D218H, I244L, S251TB
  JS98287AJ401814AZT, DDI, D4T, 3TCNoneA62V, T69S_SS, K70R, M184I, L210W, T215Y K64R, V118I, D123E, Q197E, E203K, R211K, F214W, D218H, I244L, E248KB
  JS98465AJ401829AZT, DDI, D4T, 3TCNoneA62V, T69S_SS, K70R, M184I, L210W, T215Y L34F, S48L, K64R, V118I, D123E, I142T, Q197E, E203K, R211K, F214L, D218H, L228R, I244LB
 JS24JS96388AJ401754DDC, 3TCNoneM184I K122E, D123N, D177E, R211K, V245QB
Papa (2002)AP-5AP-5AF315743DDC, AZT, D4T, 3TCNoneM41L, D67N, K70R, M184I, T215F, K219Q R83K, V90I, K122E, D123E, S162Y, E203D, H208Y, R211KB
Montes (2004)MB_patAVO01_AVO720AJ577732DDC, AZT, 3TC, D4TNoneA62V, M184I, L210W, T215SA98GR83K, I135V, S162C, T165V, I202VB
Rhee (2005)SWC-57295729-3376 AZT, 3TC, D4TNoneM41L, A62V, T69S_SS, M184I, L210W, T215Y V35M, K43E, V118I, K122E, I135T, V245QB
  5729-4183 AZT, 3TC, D4TNoneM41L, A62V, T69S_SS, M184I, L210W, T215Y V35M, K43E, V118I, K122E, I135T, V245QB
 CA7848CA19878AY801794AZT, DDI, D4T, 3TC, ABCNoneM41L, D67G, T69D, V75VL, M184I, L210W, T215Y, K219R K43KN, E44D, V60I, V118I, K122E, D123E, I135T, I142V, G196E, I202X, E203EK, Q207E, H208Y, R211K, H221HY, K223KE, V245K, A272PB
  CA23659AY801795AZT, DDI, D4T, 3TC, ABCNoneM41L, D67G, T69D, M184I, L210W, T215Y, K219RF227FLT39TP, K43KN, E44D, S48SP, V60I, V118I, K122E, D123E, I135T, I142V, G196E, E203K, Q207E, H208Y, R211K, K223E, V245K, A272P, M357T, I375V, K390R, A400T, V435I, V458I, L469I, S519N, K527Q, A554S, K558RB
 CA9700CA37961AY802073D4T, 3TCNoneM41L, D67N, M184I, L210W, T215Y, K219R E6ED, K43Q, E44D, V90I, K104R, V118I, G196E, E203K, Q207E, H208Y, R211K, K223E, V292I, I293VB
 CA9831CA24186AY802137AZT, 3TCNoneF77L, F116Y, Q151M, M184I V35I, V90I, K122E, Q207E, R211K, A272P, K277R, V292IB
 CA21096CA48506AY802582D4T, 3TC, ABC, AZT, TDFNoneM184I D123E, K166R, T200I, Q207E, K277R, I293VB
Melikian (2012)CA14602CA35008GQ207006D4T, 3TC, AZT, TDF, DDINoneM184I V35VI, R83K, V90I, K122E, S162Y, K173E, R211RK, A272P, K277R, E297XB
Mollan (2012)MK118MK118w68 TDF, FTCNoneD67DG, M184I E6D, V60I, I142V, S162A, R211K, V245K, T286A, A288S, I293VB
 MK128MK128w64 TDF, FTCNoneM184I T39A, S48E, R83K, K102KR, K104R, S162A, E169D, T200E, R211K, S251I, A272P, K275R, E291D, P294S, E297KB
 MK245MK245w53 TDF, FTCNoneM184I V8I, K104R, D123E, T200I, Q207K, V245T, T286A, I293V, E297KB
 MK89MK89w20 TDF, FTCNoneM184I D86E, W88S, V90I, I135V, I178M, I202V, R211K, V245E, V276T, K281R, T286A, I293VB
Grossman (2014)3333KF1350573TC, DDINoneM41L, D67N, T69D, K70KR, V75M, F77L, M184I, L210W, T215Y, K219R I37L, E44D, N57D, T58N, V60I, K65KE, K82KR, T84TA, D110DG, V118I, K122E, K126E, Q174K, N175Y, G196E, T200R, E203V, Q207E, R211A, D218E, Q242QLB
  33KF1350583TC, DDI, D4TNoneM41L, D67N, T69D, V75M, M184I, L210W, T215Y, K219RK101KE, V108VI, Y181YC, G190GAI37L, E44D, V60I, V118I, K122E, K126KE, Q174K, N175Y, E194ED, G196E, T200R, E203V, Q207E, R211A, D218E, Q242LB
  33 3TC, DDI, D4TNoneM41L, D67N, T69D, V75M, M184I, L210W, T215Y, K219RV108II37L, E44D, V60I, V118I, K122E, Q174K, N175Y, V179VI, G196E, T200R, E203V, Q207E, R211A, D218E, L228V, Q242LB