<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation T69N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 6
Isolates 7
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Carr (1999)SE8538SE8538AF069669AZTNoneK70R V35T, V60I, T69N, K122E, D123S, I135T, A158S, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245N, D250E, T286A, E291D, V292I, I293V, P294T, E312A, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377M, L391V, A400T, T403M, E432D, V435A, D471E, L479V, Q480H, L491S, K512S, S519N, Q524K, K527G, E529D, A534S, A554SA
Gibb (2002)DMG1111_w31 AZT, 3TCNoneM41ML, K70R, M184V, N348NI K11E, K20KR, V35T, V60I, T69N, D121H, K122E, D123S, I135T, I142IV, K173S, Q174K, D177E, V179I, Q197L, Q207A, R211S, V245IM, D250E, A272G, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357KR, G359S, T369AV, A371V, I375V, A376V, T377MA
Vergne (2002)LV01BLV01BAJ313403D4T, DDINoneK70N, V75T V35T, T39N, T69N, K122E, D123S, I135T, S162C, K173S, Q174R, D177E, T200E, Q207A, R211S, V245Q, A272P, K275R, T286A, V292I, I293V, P294T, L295M, I326V, G335D, R356K, M357K, R358K, G359S, T369A, I375V, K390R, A400T, T403M, E404D, E432DA
Montes (2004)MB_patBES00_BES703AJ577738AZT, DDI, 3TC, D4T, ABCNoneD67N, K219Q K11T, V35T, T39A, S48A, K49R, V60I, T69N, K122E, D123S, I135T, K173S, D177E, T200A, Q207A, R211S, F214LA
Non-B Workgroup (2005)TK3030TK3030 AZT, 3TC, DDINoneM41ML, K70R, T215I, K219Q V35T, T39I, V60I, T69N, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, Q197E, Q207A, R211N, V245K, D250E, A272T, T286A, I293V, P294T, L295LM, E312DA
  TK3030a AZT, 3TC, DDINoneM41ML, D67DG, K70R, T215TI, K219Q V35T, T39I, V60I, K64KN, T69N, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, Q197E, Q207A, R211NS, V245K, D250E, A272T, T286A, I293V, P294T, L295LM, E312DA
Avidor (2013)1997_MT1997_MTKC184325TDF, AZT, D4T, 3TCNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39N, T69N, K122E, D123N, K173A, Q174K, D177E, Q207A, R211S, V241D, L246VA