<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation S68G
Rx RTI-naive
IncludeMixtures No
References 24
Patients 50
Isolates 50
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Vergne (2000)LVMP1019LVMP1019AJ286932NoneNone  K11S, V35T, T39K, K43Q, K49R, S68G, D121Y, K122E, D123N, I135T, E169D, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q, E248N, K277R, T286A, E291D, I293V, E312D, G335D, M357K, G359S, A371V, I375V, S379G, T403MA
Gonzalez (2003)PG_GT652GT652AF529947NoneNone  S3R, E6K, K11T, V35T, T39R, K43E, S68G, K122E, D123N, I135T, S162H, K173S, V179I, T200A, Q207AA
Delaunay (2005)DC_00101_5005w0AY971648NoneNone  V35T, T39M, V60I, S68G, V90I, K122E, D123S, I135T, S162A, K173S, T200A, Q207A, R211SA
K'Aluoch (2005)OK_TC025204TC025204DQ079825NoneNone  K11N, V35T, V60I, S68G, D121H, K122E, I135T, K173S, Q174K, D177E, G196E, T200A, Q207A, R211S, V245Q, T286A, E291D, I293V, P294AA
Tee (2005)MYIDUC2204MYIDUC22DQ018362NoneNone  V60I, S68G, K122E, D123S, I135R, T165I, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245EA
Vazquez de Parga (2005)RU00030RU00030EU345702NoneNone  K11T, V35T, E36D, T39K, S68G, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, E194K, Q207A, R211S, P236S, V245M, E248NA
 RU00053RU00053EU345719NoneNone  V10VG, K11T, V35T, E36D, T39K, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, E194K, Q207A, R211S, V245M, E248N, T253A, I257L, A272SA
Koizumi (2006)YK_04CM008YK_04CM008DQ461881NoneNone  E6D, K11T, V35I, E36D, S68G, D121H, K122E, D123S, K173S, Q174K, D177E, I178L, V179I, T200A, Q207A, R211K, T216AA
Marechal (2006)JF_076JF_076DQ443583NoneNone  K11A, V35T, T39K, S68G, K122E, D123S, I142IV, T165I, K173A, Q174K, D177E, G196E, Q207A, R211RS, V245QA
 JF_109JF_109DQ443605NoneNone E138EKE6D, K11T, K22R, V35T, T39K, K43E, S68G, D121Y, K122E, D123G, N147NK, T165I, K173T, Q174K, D177DE, T200TA, I202IV, Q207A, R211S, K238R, V245QA
Saad (2006)MDS_01UADN18001UADN180DQ055190NoneNone  K11T, V35T, E36D, T39K, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, I195L, G196R, Q207A, R211SA
 MDS_01UADN22201UADN222DQ055193NoneNone  K11T, V35T, E36D, T39K, V60I, S68G, K122E, D123S, I135T, A158S, K173S, Q174K, D177E, Q207A, R211SA
 MDS_01UAPol29701UAPol297DQ055253NoneNone  K11T, V35T, S68G, K122E, D123S, I135T, T139TA, K173L, Q174K, Q207A, R211SA
Zarandia (2006)MZ_03GEMZ00203GEMZ002DQ205262NoneNone  K11S, V35I, E36D, T39K, S68G, K122E, D123S, I135R, A158S, K173L, Q174K, D177E, Q207A, R211SA
Galluzzo (2007)24320RW_24320JQ220020NoneNone  K49Q, V60I, S68G, I135T, E138A, S162A, K173S, Q174K, D177G, V179I, T200K, Q207A, R211SA
Rosen-Zvi (2008)8908p89-1 NoneNone  K30E, V35I, E36D, T39K, K46KQ, S68G, K122E, D123S, K173A, Q174K, D177E, V179VI, T200TI, Q207A, R211S, V245M, E248D, A272P, T286A, A288AT, E291D, V292I, I293VA
Ayouba (2009)RES605RES605RTGQ351759NoneNone  T39K, K43E, S68G, K122E, D123S, I135T, S162H, E169K, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q, K249QA
Thomson (2009)915_1001RU_915_1001FJ009713NoneNone  K11T, V35T, E36D, T39K, S68G, D121H, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 915_1003RU_915_1003FJ009715NoneNone  K11T, V35T, E36ED, T39R, S68G, K122E, D123S, I135T, A158S, K173S, Q174K, D177E, T200I, I202IV, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 915_1005RU_915_1005FJ009717NoneNone  K11T, V35T, E36D, T39K, S68G, D123S, A158S, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 915_1008RU_915_1008FJ009720NoneNone  K11T, V35T, E36D, T39K, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 915_1044RU_915_1044FJ009740NoneNone  V35T, E36D, T39K, S68G, K122E, D123S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, T286A, V292I, I293V, P294TA
 915_1047RU_915_1047FJ009743NoneNone  V35T, E36D, T39Q, S68G, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294IA
 915_1048RU_915_1048FJ009744NoneNone  K11T, V35IT, E36D, T39Q, S68G, D123ST, I135T, K173LS, Q174K, D177E, T200TA, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 915_1050RU_915_1050FJ009745NoneNone  V35I, E36D, T39K, S68G, D123S, I135M, A158S, K173L, Q174K, D177E, T200TA, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 915_1070RU_915_1070FJ009764NoneNone  K11T, V35T, E36D, T39K, V60I, S68G, K122E, D123S, I135T, A158AS, T165TI, K173S, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 915_1071RU_915_1071FJ009765NoneNone  K11T, V35T, E36D, T39K, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 SP_B_026RU_SP_B_026FJ009791NoneNone  K11T, V35IT, E36D, T39KM, S68G, K122E, D123S, A158S, K173S, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 SP_B_042RU_SP_B_042FJ009803NoneNone  K11T, T27S, V35T, E36ED, T39E, V60I, S68G, K122E, D123S, I135T, K173L, Q174K, D177EG, Q207A, R211S, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 SP_B_048RU_SP_B_048FJ009806NoneNone  K11T, V35T, E36D, T39MR, K43KR, S68G, K122E, D123S, A158S, K173S, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 SP_B_050RU_SP_B_050FJ009808NoneNone  K11T, V35T, T39K, S68G, K122E, D123S, I135T, A158S, S162C, K173L, Q174K, D177E, T200A, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 SP_B_058RU_SP_B_058FJ009813NoneNone  K11T, V35T, E36D, T39K, S68G, K102Q, K122E, D123S, K173L, Q174K, D177E, T200E, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
Balode (2010)S2282S2282GU945165NoneNone  K11T, V35T, E36D, T39R, S68G, K122E, D123N, K166R, K173L, Q174K, D177E, Q207A, V245M, E248DA
 S2303S2303GU945173NoneNone  E6K, K11T, V35I, E36D, T39K, S68G, V106VI, K122E, D123S, A158S, K173S, Q174K, D177E, Q207A, R211S, V245M, E248DA
Descamps (2010)301odyssee301odysseeHQ718134NoneNone  K30E, I31P, A33P, V35T, I37F, T39L, I63L, S68G, K122E, D123N, A158S, K173S, N175H, T200A, Q207A, R211S, T216PA
Djoko (2010)646CD3373FR666646NoneNone  K11IT, V35T, T39K, S68G, E89EG, K122E, D123N, I142V, A158S, K173L, D177E, T200A, Q207A, R211S, V245Q, K277R, T286A, E291D, V292I, I293V, E312D, I326V, Q334P, G335D, R356K, M357K, G359S, K366R, T369VA
Mosha (2010)S13PolS13PolJQ071461NoneNone  E28K, K32E, V35T, T39TK, V60I, S68G, K122E, D123S, I135T, I159V, S162A, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, D250E, A272P, K281R, T286A, E291D, I293V, P294T, E312D, G335D, M357R, R358K, G359S, A371V, I375V, A376V, A400T, T403M, E404DA
Selimova (2010)08MOSR08MOSRHM345543NoneNone  K11Q, T27P, V35I, E36D, T39K, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, T200A, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 17MOS17MOSHM345549NoneNone  T27S, E36D, T39K, S68G, D123N, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, E248D, Y271YF, A272P, V276VI, T286A, E291D, V292I, I293V, P294T, L295M, K311RA
 25MOSR25MOSRHM345556NoneNone  K11T, V35T, E36D, T39Q, S68G, D121H, K122E, A158S, K166R, K173S, D177E, T200A, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
Soares (2010)CM04_094CM04_094GU366134NoneNone  I2V, K11T, V35T, T39G, K43E, S68G, D121H, K122E, D123S, I135T, E138A, S162H, K173S, Q174K, G196E, T200A, Q207A, R211K, V245Q, E248DA
 CM04_095CM04_095GU366143NoneNone  K11T, V35M, T39S, S68G, D121Y, K122E, I135T, T139M, S162C, E169D, K173A, Q174K, D177E, V179I, G196E, Q207A, R211S, V245QA
Tovanabutra (2010)KECst_017KECst_017FJ623488NoneNone  P4H, K11E, V35T, V60I, S68G, D121Y, K122E, D123G, I135T, K173S, Q174K, I178L, V179I, T200A, Q207A, R211S, V245E, D250E, A272P, K277R, E291D, I293V, E312D, G335E, R356K, M357K, R358K, G359S, K366R, T369A, A371V, I375V, A376T, T377Q, S379A, A400T, T403M, E404D, E432D, V435A, V467I, D471E, Q480H, H483Y, L491S, E492Q, L517V, S519N, Q524K, K527E, E529D, A534S, A554S, V559IA
 KECst_004KECst_004FJ623489NoneNone  V35T, V60I, S68G, K173A, Q174K, D177E, V179I, I195K, Q207A, R211S, F214L, H221Y, D250E, A272P, K275T, K277R, T286A, E291D, V292I, I293V, P294T, E312S, S322A, G335D, M357K, G359S, T369S, I375V, A376T, T377L, T386A, A400T, T403M, E404D, E432D, V435I, V467I, D471E, Q480H, L491S, I495V, Q524K, K527E, E529D, A534S, A554SA
Hamers (2011)CP076301537CP076301537HQ993581NoneNone  V35T, T39A, V60I, S68G, K122E, D123DN, I135T, F171Y, K173S, Q174K, V179I, T200A, Q207A, R211S, V245X, E248EK, D250DE, S251SHNR, K275R, K277Q, T286A, E291D, I293V, P294T, E297KA
 CP076304157CP076304157HQ993882NoneNone  V35T, T39A, V60I, S68G, D121H, K122E, I135T, K173IT, Q174K, D177E, V179I, T200A, Q207A, R211S, D250E, S251N, T286A, E291D, V292I, I293V, P294PT, E312DA
 CP076304250CP076304250HQ993939NoneNone  K11Q, V35T, T39M, V60I, S68G, D121H, K122E, D123N, I135T, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, T286A, E291D, V292I, I293V, P294TA
 CP076300767CP076300767HQ994938NoneNone  E6D, V35T, V60I, S68G, K122E, D123N, I135T, I159V, K173T, Q174K, D177E, T200A, Q207A, R211S, V245Q, D250E, A272P, T286A, E291D, I293VA
Hassan (2013)RS11000250RS11000250JQ698350NoneNone  K11T, V35T, T39EK, K43KE, I50V, V60I, S68G, D121CY, K122E, I135T, K173S, Q174K, D177DE, V179VI, Q207A, R211S, F214FL, V245E, D250E, A272P, T286A, E291D, V292I, I293V, E312D, G335DA
Kiptoo (2013)SNH080SNH080KC516984NoneNone  V35T, T39A, E40D, V60I, S68G, D121H, K122D, D123S, I135T, K173LV, Q174K, D177E, I178M, V179VI, T200A, Q207A, R211S, P243S, V245E, E248I, D250E, T286A, E291D, I293V, P294T, K311R, E312DA