<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation S68G
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 7
Patients 11
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Yahi (2001)NY_M49M49AY010452AZT, 3TCNoneM184VA98AGT27S, V35X, K43EQ, K49KR, S68G, D121Y, K122E, D123G, I135T, K166KR, K173I, Q174K, D177E, I195IL, G196E, E203EK, Q207A, R211S, F214LA
Vergne (2002)LV04BLV04BAJ313406AZT, D4TNoneK65R, K70R, V75I, F77L, F116Y, Q151M K11T, V35T, T39K, K43E, S68G, D121Y, K122E, D123G, K173S, Q174K, I180V, Q207A, R211S, V245Q, E248D, K277R, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, M357K, G359S, K366R, I375V, T377Q, S379C, K390R, T403M, K431T, E432D, V435AA
Richard (2004)RNJCR52RNJCR52AY556842AZT, 3TC, D4T, DDI, ABCNone  V35T, T39E, V60I, S68G, K122E, I135T, E138A, K173L, Q174K, D177E, I178MA
Delaunay (2005)DC_00101_5004w12DQ286519ABC, TDF, 3TCNone  V35T, T39M, V60I, S68G, V90I, K122E, D123S, I135T, S162A, K173S, T200A, Q207A, R211SA
von Wyl (2007)70496347EF449835NRTINoneM184V V35M, T39K, S68G, K122E, D123N, K173A, T200A, Q207A, R211SA
Thomson (2009)D1RU_D1FJ009776AZTNone  K11T, V35T, E36D, T39K, S68G, K122E, D123S, I142IT, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 D9RU_D9FJ009779AZT, 3TCNone  K11T, V35T, E36ED, T39R, S68G, K122E, D123S, E138A, A158S, K173L, Q174K, D177E, I178M, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294TA
 SP_B_005RU_SP_B_005FJ009783ABC, AZT, 3TCNone  K11T, V35I, E36D, T39K, S48T, S68G, K122E, D123S, A158S, K173L, Q174K, T200TK, Q207A, R211S, V245M, E248D, A272P, K277KR, T286A, E291D, I293V, P294T, E297KA
 SP_B_031RU_SP_B_031FJ009796AZT, 3TC, D4TNone  K11T, V35T, E36D, T39K, S68G, K122KE, D123G, K173L, Q174K, D177EK, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 SP_B_057RU_SP_B_057FJ009812AZT, 3TCNone  K11T, V35T, T39E, S68G, D123N, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, A272P, T286A, E291D, V292I, I293V, P294T, L295MA
Ndembi (2010)16735D_P116735GQ409589ABC, AZT, 3TC, D4TNoneK65R, K70R, V75I, F116Y, Q151M, M184V V35T, K43R, V60I, S68G, D121H, K122E, K173S, Q174K, D177E, I178M, T200M, Q207E, R211K, F214LA