<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation A62V
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 52
Isolates 59
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gibb (2002)DMG106106_w41 AZT, 3TCNoneA62V, M184V E6D, K11T, K20R, V35T, K122E, D123N, K173S, D177E, V179I, T200A, I202V, Q207A, V245Q, E248D, T286A, E291D, V292VI, I293V, E312N, S322SA, I326V, G335D, M357K, G359S, K366R, T369A, A371V, K374R, I375V, A376V, T377RA
 DMG6868_w27 ABC, AZTNoneA62V, M184V E6D, K11T, K20R, V35T, K122E, D123N, K173S, D177E, V179I, T200A, I202V, Q207A, V245Q, E248D, T286A, E291D, V292I, I293V, E312N, S322A, I326V, G335D, K353KR, M357K, G359S, K366R, T369A, A371V, K374R, I375V, A376V, T377MA
  68_w30 ABC, AZTNoneA62V, M184V E6D, K11T, K20R, V35T, K122E, D123N, F171FL, K173S, D177E, V179I, T200A, I202V, Q207A, V245Q, E248D, T286A, E291D, V292I, I293V, E312N, S322A, I326V, G335D, M357K, G359S, K366R, T369A, A371V, K374R, I375V, A376V, T377MA
Thomson (2009)D5RU_D5FJ009777AZTNoneA62V K11T, V35I, E36D, T39K, K49KR, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 SP_B_051RU_SP_B_051FJ009809TDF, FTCNoneA62V K11T, E28K, K32E, V35I, E36D, T39K, V90I, K122E, D123S, E138A, A158S, K173L, Q174K, I178M, Q207A, R211S, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
Avidor (2013)1756_FN1756_FNKC184227AZT, 3TCNoneA62V K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, V90I, V118VI, K122E, D123NS, I135IT, A158S, K173L, Q174K, D177DE, T200A, Q207A, R211S, V245VMA
 19191919 AZT, 3TCNoneA62V, M184V T39N, K101KQ, K122E, D123N, I135T, E138G, A158S, K173LS, Q174K, D177EG, I178IL, T200A, Q207A, R211SA
Grossman (2014)14601460KC184186TDF, FTCNoneA62V T39K, I50IV, K82KR, D121H, K122E, D123S, A158AS, S162A, K173I, Q174K, D177E, I178L, T200TA, Q207A, R211SA
Kolomeets (2014)335335_474KJ8705493TC, DDINoneA62V, M184V K11T, V35T, T39K, K122E, D123N, A158S, K166R, K173L, Q174R, T200A, Q207A, R211S, V245K, E248DA
 182182_327KJ870438AZT, 3TCNoneA62V, M184V K11KT, V35T, E36D, T39K, V90I, K102Q, K122E, D123N, A158AS, S162SACG, K166KR, K173X, Q174K, D177E, Q207A, R211S, V245M, E248DA
 430430_630KJ870658AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, E40EK, E42EK, E53EK, K122V, D123N, I135T, K173L, Q174K, D177G, Q207A, R211S, D218DN, G231GE, V245K, E248DNA
 331331_470KJ870546AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, T69TS, D123DN, Q174K, Q207A, R211S, V245MT, E248DA
 195195_344KJ870452D4T, 3TCNoneA62V K11T, K32N, V35I, T39K, K122E, D123N, A158AS, T165TI, E169D, K173X, Q174K, T200A, Q207A, R211S, V245VM, E248DA
 7676_88KJ870262AZT, 3TCNoneA62V K11T, V35T, E36D, T39K, K82R, K122E, D123DN, Q174K, D177E, T200TK, Q207A, R211S, E248DA
 1111_139KJ870288AZT, 3TCNoneA62V, M184V K11T, E36D, T39K, K122E, D123N, K173L, Q174K, D177E, T200A, E203D, Q207A, R211S, V245M, E248DA
 297297_395KJ870495AZT, 3TCNoneA62V K11T, V35I, E36ED, T39KN, V90VI, K122E, D123S, E138A, K173LS, Q174K, V179VI, T200A, Q207A, R211S, V245VM, E248DA
 162162_192KJ8703333TC, DDINoneA62V, M184V K11T, V35IT, E36D, T39K, K82R, K122E, D123N, Q174K, Q207H, L210S, E248DA
 442442_639KJ8706643TC, DDINoneA62V, M184V K11T, E28E_SWF, V35I, E36D, T39Q, V90VI, K101R, K122E, D123N, I135T, K173L, Q174K, D177E, T200TI, R206RK, Q207A, R211RS, V245MT, E248DA
 3737_591KJ870627AZT, 3TC, ABCNoneA62V S3SG, E6EG, V35T, E36D, T39K, K122E, D123S, A158S, K173L, Q174K, D177E, I178L, Q207A, R211SA
 394394_450KJ870532ABC, AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, T69TS, K102KQR, D121DY, K122E, D123DN, K166R, P170T, K173ILST, Q174KR, D177E, G196GE, T200I, Q207A, R211S, V245M, E248EKA
 309309_408KJ870502AZT, 3TCNoneA62V, M184V K11T, V35T, E36D, T39K, K82R, K122E, D123NS, A158AS, K173S, Q174K, D177E, Q207A, R211S, V245M, E248DA
 175175_272KJ870393AZT, 3TCNoneA62V, M184V K11T, V35I, E36D, T39K, P119PL, K122E, D123N, K173S, Q174K, D177E, T200I, Q207A, R211S, V245M, E248DA
 423423_577KJ870619AZT, DDINoneA62V T39N, V90I, K122E, D123N, K126KE, K173L, Q174K, D177E, Q207A, R211S, E248DA
 307307_405KJ870500AZT, 3TCNoneA62V, M184VV179DK11T, T27TK, V35I, E36D, T39K, V90I, K103R, K122E, D123S, A158S, K173I, Q174K, I180IL, G196GE, Q207A, R211S, V245M, E248DA
 137137_304KJ870418AZT, 3TCNoneA62V K11T, V35IT, E36D, T39K, I50V, T69S, K122E, D123N, A158S, K173L, Q174K, D177E, T200A, E204ED, Q207A, R211S, V245MA
 1717_275KJ8703963TC, DDINoneA62VG190FV35I, E36D, T39E, D123N, A158S, K173S, Q174K, G196E, Q207A, L210LM, R211S, E248DA
 104104_288KJ870406ABC, 3TCNoneA62V, M184V K11T, V35I, E36D, T39K, K82R, K122E, D123N, A158S, Q174K, D177E, T200A, Q207A, R211S, V245K, E248DA
 276276_507KJ870571AZT, 3TCNoneA62V K11S, E28K, K32E, V35I, E36D, T39K, V60I, K73KE, V90I, S105SP, K122E, D123N, F124FL, T131TI, I132IL, I135T, S162Y, K173L, Q174K, D177E, V179I, S191SP, E204K, Q207A, L210F, R211K, V245T, E248DA
 143143_311KJ870425AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, V90VI, D123S, A158S, K173IL, Q174K, D177E, T200I, Q207A, R211S, V245M, E248DA
 196196_346KJ870454AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, V60I, K122E, D123N, A158AS, K173L, Q174K, D177E, T200I, Q207A, R211S, V245MA
 327327_464KJ870543AZT, 3TCNoneA62V K11T, K122E, D123S, K173L, Q174K, D177E, Q207A, R211S, E248DA
 265265_230KJ870364AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, T69TS, K122E, D123N, A158S, K173L, Q174K, D177E, Q207A, R211S, E248DA
 343343_521KJ8705813TC, DDINoneA62V K11T, V35I, E36D, T39K, D121H, K122E, A158S, K173*Q, Q174K, D177E, T200TA, Q207A, R211S, V245M, E248DA
 4040_364KJ870470ABC, AZT, 3TCNoneA62V, M184MV, T215TNSYK101KE, E138EKT7TA, K11T, V35I, E36D, T39K, K122E, D123N, K173L, Q174K, T200TAIV, E203D, Q207A, R211RKNS, E248DA
 441441_636KJ870661AZT, 3TCNoneA62VE138EKK11T, V35I, E36D, T39K, D121H, K122E, D123S, A158S, S162D, K166R, K173L, Q174K, D177E, T200A, Q207A, R211S, E248DA
 4040_490KJ870558ABC, AZT, 3TCNoneA62V, M184V K11T, V35IT, T39K, T69S, K122E, D123N, R143G, A158S, K166R, K173L, Q174R, T200A, Q207A, R211S, V245KM, E248DA
 3333_328KJ870439ABC, 3TCNoneA62V, L74LV, Y115YF, M184V E6N, K11T, V35I, E36D, T39K, K82KR, K122E, D123S, K166T, K173V, Q174K, D177E, V179I, Q207A, R211S, V245M, E248DA
 410410_599KJ870631AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, K43E, K49R, K102KQ, K122E, D123N, A158S, K173L, Q174K, D177E, I202V, Q207A, R211S, E248DA
 9898_250KJ870375ABC, AZT, 3TCNoneA62V, M184V V35I, T39K, K122E, D123S, I135T, A158S, S162Y, K173A, Q174N, D177E, Q207A, R211S, L228R, E248DA
 3737_529KJ870586AZT, 3TCNoneA62V E6EA, K11KT, V35I, E36D, T39K, K122E, D123GS, A158S, K173L, Q174K, D177E, I178L, Q207A, R211S, V245MA
 277277_508KJ870572D4T, 3TCNoneA62V, M184V K11A, V21I, E28G, V35I, E36D, T39E, K66R, T69S, E89G, V90I, P119R, K122E, K173L, Q174K, D177E, T200A, Q207A, R211S, E248DA
 2525_415KJ8705073TC, DDINoneA62V, M184V K11T, V35I, E36D, T39K, V90I, K122E, D123N, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248DA
  25_137KJ8702863TC, DDINoneA62V K11T, V35I, E36D, T39K, V90I, K122E, D123N, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248DA
 189189_338KJ870448ABC, 3TCNoneA62V K11T, V35I, T39E, K82R, K122E, D123N, A158S, K173L, Q174K, D177E, I178M, T200TA, Q207A, R211S, F214I, E248DA
 110110_355KJ870462D4T, 3TCNoneA62V K11T, V35I, E36ED, T39EK, K122E, D123N, K173L, Q174K, D177E, T200TA, Q207A, R211S, E248DA
 340340_517KJ870578AZT, 3TCNoneA62V, M184V K11T, K13*, V35K, E36D, T39A, K82R, W88WC, K122V, D123N, K173I, Q174K, D177E, I178L, Q207A, R211S, V245TA
 316316_419KJ870510AZT, 3TCNoneA62V, M184V K11T, V35I, E36D, T39K, V118I, K122E, D123S, I142IV, A158S, K173L, Q174K, D177E, T200I, E203D, Q207A, R211S, V245T, E248D, D250DNA
 191191_340KJ8704503TC, DDINoneA62V K11T, V35I, E36D, T39K, K122E, D123N, I135T, A158S, T165I, K173S, Q174K, D177E, Q207A, R211S, K220KE, E224EG, V245M, E248DA
 283283_436KJ870523AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, I47F, S48SP, K82R, K122E, D123S, A158S, K173S, D177E, Q207A, R211S, V245M, E248DA
 1111_417KJ870509AZT, 3TCNoneA62V, M184V E6EK, K11T, E36D, T39K, K122E, D123N, I135T, K173L, Q174K, D177E, T200A, E203D, Q207A, R211S, V245MT, E248DA
 183183_329KJ870440AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, K82R, K122E, D123S, A158S, K166R, K173L, Q174K, D177G, Q207A, R211S, V245M, E248DA
 177177_276KJ870397ABC, 3TCNoneA62V K11T, T39K, V118I, D123N, F214L, V245M, E248DA
 3333_461KJ870540ABC, 3TCNoneA62V, Y115F, M184V E6N, K11T, V35I, E36D, T39K, K122E, D123S, S163A, K166T, K173V, Q174K, D177E, V179I, Q207A, R211S, K238KR, V245M, E248DA
 1717_134KJ8702833TC, DDINoneA62V, M184V K11T, V35I, E36D, T39E, D123N, A158S, K173S, Q174K, D177E, G196E, Q207A, R211S, E248DA
 280280_552KJ870603AZT, 3TCNoneA62V K11T, V35I, E36D, T39K, K122KE, D123S, E138A, A158S, K173LPS, Q174K, I202IV, Q207A, R211S, V245M, E248DA
 193193_342KJ870451AZT, 3TCNoneA62V, M184V K11T, V35T, E36D, T39K, K122E, D123N, K173L, Q174K, Q207A, R211S, V245M, E248DA
 8686_123KJ870276AZT, 3TCNoneA62V K11T, E36D, T39K, K122E, D123N, A158S, K173L, Q174K, D177E, Q207A, R211S, V245M, E248DA
 9494_213KJ870349ABC, 3TCNoneA62VV108VIL12X, V35I, E36D, T39N, L109LI, D121H, K122E, K173I, Q174K, D177E, I178L, T200TA, Q207A, R211S, V245T, E248DA
 474474_650KJ870672AZT, 3TCNoneA62V K11T, K22KN, Q23QK, V35I, E36D, T39K, V90VI, K122E, D123N, A158S, E169EK, K173A, Q174K, D177E, Q207A, R211S, V245MA