<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation E44D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 6
Isolates 6
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Shafer (2003)A384_09830983bEF548169AZT, 3TCNoneM184V T39A, E44D, V60I, D121H, K122E, D123S, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211KA
Non-B Workgroup (2005)PL3892365841AY901690DDC, TDF, AZT, D4TNoneM41L, D67DN, T215Y S3ST, V35T, T39N, E44D, V60I, V111VG, D121DN, K122E, D123S, K173A, Q174K, D177E, I178M, G196E, T200A, E204KN, Q207E, R211K, V245Q, P247A, E248D, S251H, A272P, T286A, E291D, V292I, I293V, P294VA
Ndembi (2010)14006D_P114006GQ409562ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215FA98G, G190AE6EK, V35T, E44D, S48E, V60I, K122E, D123N, I135L, K166R, K173S, D177E, V179I, G196E, T200A, E203D, Q207A, R211NSA
 DT4014_05_P14014GQ409629ABC, AZT, 3TCNoneM184V V35T, E44D, K49R, I50V, V60I, K104Q, D121H, K122E, D123T, I135T, I142V, E169D, K173A, Q174K, D177E, V179I, G196E, T200L, Q207AA
Sigaloff (2011)HIV100812HIV100812JN132247ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YK103N, G190AK11T, V35T, T39E, E44D, K102R, V118I, K122E, D123N, I135T, K173L, Q174K, D177E, T200A, E203D, Q207A, R211N, V245Q, D250E, A272P, T286TP, E291D, V292I, I293VA
 HIV100840HIV100840JN132250ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YG190AI2IV, K11T, K20R, V21I, V35T, T39D, E44D, E53D, V111I, K122E, D123S, I142V, K173S, Q174K, D177E, I178M, V179I, T200A, I202V, E203D, Q207A, H208Y, R211K, H221Y, V245Q, E248D, A272P, T286A, E291DA