<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K219Q
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 6
Isolates 7
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patBES00_BES703AJ577738AZT, DDI, 3TC, D4T, ABCNoneD67N, K219Q K11T, V35T, T39A, S48A, K49R, V60I, T69N, K122E, D123S, I135T, K173S, D177E, T200A, Q207A, R211S, F214LA
Snoeck (2004)BE25BE25AY901287AZTNoneD67N, K70R, K219Q K11T, V35IT, T39X, V60VI, T69TN, K122E, D123N, I135T, E138EA, I142IV, K166R, K173S, I202V, Q207A, R211S, F214L, V245Q, E248D, K277R, T286A, E291D, V292VI, I293V, P294V, E312NA
Non-B Workgroup (2005)TK3030TK3030 AZT, 3TC, DDINoneM41ML, K70R, T215I, K219Q V35T, T39I, V60I, T69N, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, Q197E, Q207A, R211N, V245K, D250E, A272T, T286A, I293V, P294T, L295LM, E312DA
  TK3030a AZT, 3TC, DDINoneM41ML, D67DG, K70R, T215TI, K219Q V35T, T39I, V60I, K64KN, T69N, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, Q197E, Q207A, R211NS, V245K, D250E, A272T, T286A, I293V, P294T, L295LM, E312DA
 TK5002TK5002 D4T, 3TCNoneD67N, T69D, K70R, M184V, K219QA98GK11T, V35T, E40D, K49R, V60I, K122E, D123S, I135T, S162A, T165I, K173S, D177E, V179I, Q207A, R211S, F214L, D218E, V245Q, A272P, E291D, I293V, P294T, E312D, D324EA
Ndembi (2010)13228D_P113228GQ409549ABC, AZT, 3TCNoneD67N, K70R, M184V, K219Q I5V, E6D, V35T, V60I, S68SR, K122E, D123S, I135T, K173S, Q174K, D177E, Q197E, Q207A, R211N, H221YA
 16182D_P116182GQ409582ABC, AZT, 3TC, D4TNoneM41L, D67N, K70R, L74I, M184V, T215F, K219QK103NV21I, V35T, T39K, V60I, V90I, K102Q, K122E, D123G, K173S, D177E, T200A, I202V, Q207EA

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