<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K219E
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 2
Patients 6
Isolates 6
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK2012TK2012 AZT, 3TC, D4TNoneD67N, M184V, T215F, K219E V35I, V60I, K122E, D123S, I135T, I142V, K173A, D177E, V179I, T200A, Q207A, R211RS, V245E, A272P, K281R, E291D, I293V, P294TA
 TK2029TK2029 AZT, 3TC, D4T, ABCNoneM41L, D67N, K70R, M184V, T215F, K219EA98GV35T, T39A, V60I, S117X, K122E, D123S, I135T, I167V, K173S, Q174K, D177E, V179I, T200A, E203D, Q207A, R211NS, L228H, Q242H, V245T, D250E, T286A, E291D, I293V, P294T, E312DA
 PL4985392544 ABC, AZT, 3TCNoneD67N, K70R, M184V, T215I, K219E S3R, K11S, V35T, T39N, K64KN, K122E, D123N, A158S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, A272P, K281KR, E291D, I293V, P294PT, L295M, E297KQ, E312DA
Ndembi (2010)14888D_P114888GQ409570ABC, AZT, 3TCNoneD67N, K70R, M184V, T215I, K219E I31V, V35T, T39A, E40D, K122E, D123S, K173G, Q174K, V179I, T200A, Q207A, R211S, F214LA
 DT2829_05_P12829GQ409610ABC, AZT, 3TCNoneD67N, K70R, M184V, T215I, K219E V21I, V35T, T69A, K122Q, D123S, E169D, K173S, Q174K, D177E, I178L, V179I, T200A, I202V, Q207A, R211SA
 DT3994_05_P13994GQ409628ABC, AZT, 3TCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219E E6D, K11I, V35T, T39K, K43E, K122E, D123S, I135T, S162C, K173T, Q174K, G196E, T200A, Q207A, R211KA

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