<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation T215Y
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 9
Patients 23
Isolates 23
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Weidle (2001)PW_UG460PW_UG460bAY901269AZT, 3TCNoneM41ML, M184V, T215Y V35T, S48T, V60I, V90I, K122E, D123S, I135T, S162F, T165I, K173AT, Q174K, D177E, T200A, Q207A, R211S, V245K, D250E, A272P, T286A, E291D, V292VI, I293V, P294T, E312D, G335D, M357R, G359S, T369A, A371V, I375V, T377M, A400TA
Yahi (2001)NY_M25M25AY010502AZT, 3TC, DDINoneL210W, T215Y V21I, E28K, K32E, V35T, T39TK, V60VI, K64R, T69S, D121HY, K122E, I135T, I142V, K166K*, E169D, K173A, Q174K, D177E, I178L, V179I, G196E, T200A, E204K, Q207A, R211SA
 NY_M27M27AY010465AZT, 3TC, DDINoneD67E, L210W, T215YY181C, G190AV21I, V35T, T39TA, K101Q, D121H, K122E, K173S, Q174R, D177E, I178M, G196GE, T200TI, Q207N, R211RK, L228HA
Vergne (2003)VL00SN69HPD00SN69AJ583752D4T, DDINoneM41L, M184V, T215Y K11T, V35T, T39A, V118I, K122E, D123N, I135T, K173S, Q174K, D177E, I178V, V179I, Q197E, Q207A, R211S, F214L, V245K, D250E, A272P, A288S, E291D, I293V, P294T, G335D, R356K, M357R, G359S, V365I, A371V, I375V, A376G, T377L, A400T, T403M, E404D, E432NA
Montes (2004)MB_patMOU00_MOUL723AJ577956AZT, DDI, D4T, 3TCNoneD67N, K70S, M184V, T215Y K11T, V35T, E36A, T39K, K43E, D121H, K122E, D123S, I135T, I142V, S162Y, F171Y, K173S, D177E, V179I, T200A, Q207AA
Non-B Workgroup (2005)UK2088UK2088AY901395AZT, 3TCNoneM41L, M184V, L210W, T215Y K11T, K20R, V21I, V35T, T39G, V60I, K122E, D123N, I135T, E138A, I142V, K173S, D177E, V179I, T200A, I202V, Q207AA
 PL972860099AY901680D4T, DDI, DDC, AZTNoneM41L, M184V, L210W, T215Y V35T, K43KE, V118VI, D121H, K122E, I135T, I142V, K173S, Q174K, D177E, T200A, Q207A, R211K, V245K, K281R, T286A, E291D, V292I, I293V, E297K, A304E, E312N, D320E, D324E, I329VA
 PL3892365841AY901690DDC, TDF, AZT, D4TNoneM41L, D67DN, T215Y S3ST, V35T, T39N, E44D, V60I, V111VG, D121DN, K122E, D123S, K173A, Q174K, D177E, I178M, G196E, T200A, E204KN, Q207E, R211K, V245Q, P247A, E248D, S251H, A272P, T286A, E291D, V292I, I293V, P294VA
 PL3943966997 AZT, DDI, 3TC, D4TNoneM41L, K70Q, L210W, T215Y K22R, V35T, T39K, K43E, V106I, K173T, Q174KR, D177E, G196E, T200K, I202V, Q207D, R211K, L228H, V245Q, A272P, L283I, T286A, I293V, P294T, E297NA
 TK2017TK2017 AZT, 3TCNoneT215Y E6K, V21I, V35T, S48T, K49R, V60I, D121H, K122E, I135T, K173L, Q174K, D177E, V179I, Q207A, L210I, R211N, V245K, D250E, T286A, E291D, V292I, I293V, E312NA
Weber (2005)F45753F45753AY677506AZT, D4T, 3TC, DDI, ABCNoneM41L, D67N, M184V, L210W, T215Y K11T, K20R, V21I, V35T, T39S, E44ED, V60I, D121H, K122E, D123S, D177E, V179I, T200A, I202V, Q207A, V245K, D250E, S251H, T286A, E291D, V292I, I293V, P294T, E312DA
 M92470M92470AY677531AZT, 3TCNoneM41L, M184V, L210LW, T215Y V35IT, T39A, E40D, K122E, D123S, I142V, K173T, T200A, Q207D, V245Q, K277R, K281KR, E291D, I293V, P294TA
Ndembi (2010)14493D_P114493GQ409569ABC, AZT, 3TCNoneM184V, T215Y K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, K173S, Q174K, D177G, I178L, V179I, T200A, I202V, Q207AA
 16712D_P116712GQ409588ABC, AZT, 3TCNoneD67N, K70R, M184V, T215Y K11T, K20R, V21I, V35T, T39N, K122E, D123N, I135T, S162H, K173S, Q174K, D177E, I178L, V179I, T200A, I202V, Q207A, R211SA
 DT3504_05_P13504GQ409618ABC, AZT, 3TCNoneD67N, K70T, Y115F, M184V, T215Y P4T, E6D, V35T, D121H, K122E, I135T, G141A, I142S, D177E, I178M, T200A, E204K, Q207E, R211KA
 DT3513_05_P13513GQ409619ABC, AZT, 3TCNoneM184V, T215Y E6D, E28A, V35T, T39E, V60I, V118I, K122E, I135T, T139R, I142T, T165I, K173S, Q174K, V179I, T200A, Q207A, R211S, F214LA
 DT3994_05_P13994GQ409628ABC, AZT, 3TCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219E E6D, K11I, V35T, T39K, K43E, K122E, D123S, I135T, S162C, K173T, Q174K, G196E, T200A, Q207A, R211KA
Sigaloff (2011)HIV100812HIV100812JN132247ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YK103N, G190AK11T, V35T, T39E, E44D, K102R, V118I, K122E, D123N, I135T, K173L, Q174K, D177E, T200A, E203D, Q207A, R211N, V245Q, D250E, A272P, T286TP, E291D, V292I, I293VA
 HIV100840HIV100840JN132250ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YG190AI2IV, K11T, K20R, V21I, V35T, T39D, E44D, E53D, V111I, K122E, D123S, I142V, K173S, Q174K, D177E, I178M, V179I, T200A, I202V, E203D, Q207A, H208Y, R211K, H221Y, V245Q, E248D, A272P, T286A, E291DA
Acharya (2014)DGP185DGP185KJ185355TDF, 3TCNoneM41L, D67N, T69D, V75M, M184V, L210W, T215YK101E, Y188LK11E, V35T, V60I, V106I, D121Y, K122E, D123G, T165I, K173T, Q174N, D177E, Q197K, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294TA
 DGP096DGP096KJ185266TDF, 3TCNoneM41L, L74I, M184V, L210W, T215YK103N, V108IK11E, V35T, V60I, D121Y, K122E, D123G, T165I, K173T, Q174N, D177E, Q197K, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294TA
 DGP088DGP088KJ185258TDF, 3TCNoneM41L, D67N, V75M, M184V, L210W, T215Y, K219EY188L, K238TK11E, V35T, V60I, D121H, K122E, D123S, I135T, S162H, K173S, Q174K, D177E, V179I, Q197K, T200A, I202V, R206K, Q207A, R211S, V245M, D250E, I293V, P294TA
 DGP029DGP029KJ185199AZT, 3TCNoneT215YK103NV35T, V60I, K122E, D123S, I135T, I142V, S162A, T165I, K173S, Q174K, D177E, V179I, Q197E, T200A, Q207A, R211K, V245K, D250E, T286A, E291D, V292I, I293V, P294TA