<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation T215F
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Si-Mohamed (2000)AS_PINAS_PINAF199289AZTNoneD67N, K70R, T215F, K219Q K122E, D123N, K173T, Q174K, D177E, I178M, G196E, T200A, E203K, Q207A, R211KA
Yahi (2001)NY_M29M29AY010488D4T, 3TCNoneM41L, M184V, T215F V35T, E36A, T39K, K43E, K49KR, E53D, T69S, D121H, K122E, D123S, I142V, S162D, K173S, Q174K, D177E, Q207AA
Non-B Workgroup (2005)TK2012TK2012 AZT, 3TC, D4TNoneD67N, M184V, T215F, K219E V35I, V60I, K122E, D123S, I135T, I142V, K173A, D177E, V179I, T200A, Q207A, R211RS, V245E, A272P, K281R, E291D, I293V, P294TA
 TK2029TK2029 AZT, 3TC, D4T, ABCNoneM41L, D67N, K70R, M184V, T215F, K219EA98GV35T, T39A, V60I, S117SAP, K122E, D123S, I135T, I167V, K173S, Q174K, D177E, V179I, T200A, E203D, Q207A, R211NS, L228H, Q242H, V245T, D250E, T286A, E291D, I293V, P294T, E312DA
 TK4003TK4003a AZT, 3TCNoneM41L, M184V, T215F V35T, K122E, D123S, I135V, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, T216TR, V245Q, D250E, S251SDGN, A272AP, K275KQ, T286A, E291D, V292I, I293V, E312DA
Ndembi (2010)14006D_P114006GQ409562ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215FA98G, G190AE6EK, V35T, E44D, S48E, V60I, K122E, D123N, I135L, K166R, K173S, D177E, V179I, G196E, T200A, E203D, Q207A, R211NSA
 16182D_P116182GQ409582ABC, AZT, 3TC, D4TNoneM41L, D67N, K70R, L74I, M184V, T215F, K219QK103NV21I, V35T, T39K, V60I, V90I, K102Q, K122E, D123G, K173S, D177E, T200A, I202V, Q207EA
 DT3340_05_P13340GQ409635ABC, AZT, 3TCNoneM41L, D67DN, K70KR, M184V, T215F E6D, V35T, V60I, K122E, D123N, I135T, T139K, I142V, A158E, K173A, Q174K, D177E, T200E, Q207A, R211KA
von Wyl (2010)48150864815086GQ848149D4T, DDINoneM41L, T215F K11T, K20R, V35T, T39G, K173S, D177E, V179I, T200A, Q207A, R211K, V245K, T286A, A288AT, E291D, V292I, I293V, P294T, E312D, V317VA, G335D, M357K, G359S, T369TA, A371V, I375V, A376V, T377M, E396D, A400TA
Acharya (2014)DGP156DGP156KJ185326TDF, 3TCNoneM184V, T215FK103N, V106M, Y188F, M230LK11E, V35T, V60I, D121H, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, Q197E, T200A, E203D, Q207A, R211S, V245Q, D250E, T286A, E291D, I293VA
 DGP152DGP152KJ185322TDF, 3TCNoneM41L, D67N, K70R, L74I, M184V, T215F, K219QA98G, K103N, P225HK11E, V35T, V60I, D121Y, K122E, D123G, T165I, K173T, Q174N, D177E, Q197K, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294TA
 DGP122DGP122KJ185292AZT, 3TCNoneM41L, D67N, M184V, L210W, T215FG190AK11E, V35T, V60I, D121H, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, Q197E, T200A, E203D, Q207A, R211S, V245Q, D250E, T286A, E291D, I293VA