<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation V118I
Rx RTI-naive
IncludeMixtures No
References 32
Patients 55
Isolates 55
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Cornelissen (1997)92UG03192UG031AF009398NoneNone  E6D, V35T, E40D, V60I, V118I, K122E, D123N, I135T, E138A, I142V, K173S, Q174K, V179I, T200A, Q207G, R211S, F214L, V245E, D250E, S251H, T286A, E291D, V292I, I293V, P294AA
Becker-Pergola (2000)171.005BPG171-005AF177366NoneNone  E6D, V35T, E40D, K43R, V118I, K122E, D123N, I135T, S162G, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, P243S, V245E, A272P, K281R, E291D, I293V, P294T, E312DA
Konings (2004)KFA_01CMNYU520301U5203AY534744NoneNone  V35T, E40D, S48T, V60I, V118I, K122E, D123N, K173S, I202V, Q207A, R211S, F214L, V245Q, E248D, D250E, S251N, Y271F, A272P, V276I, T286A, E291D, V292I, I293V, P294T, L295M, E297Q, E312D, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, A376S, T386I, K390R, A400L, E432D, V435L, L452S, R461K, V467I, S468T, D471E, Q480H, H483Y, L491S, K512S, L517I, S519N, Q524K, K527E, K530R, A534SA
Snoeck (2004)BE65BE65AY901498NoneNone  K22R, E28EA, V35T, T39E, E40D, K49KR, I50IV, V118I, K122E, D123NS, I135T, K173L, Q174K, D177E, Q207A, R211S, F214L, V245X, E248ED, D250DE, S251SN, K281R, T286A, E291D, V292I, I293V, P294T, E312DN, D320DE, D324EA
Vessiere (2006)AV_M5348NAV_M5348NDQ297343NoneNone V179DE6K, K11T, V35T, T39TA, V118I, D121E, K122E, D123S, I142V, K173S, Q174K, I202V, Q207A, R211S, F214L, V245Q, E248DA
Church (2007)445-124360B445EF612029NoneNone  E6N, V8VI, V35T, E40ED, V60I, V118I, K122E, D123S, I135T, K173A, Q174K, V179I, Q207A, R211S, F214L, V245E, D250E, A272P, T286A, E291D, I293V, E312DA
McNulty (2007)Cam32Cam32PLDQ869193NoneNone  E6N, V8I, K11T, V35T, E40D, V118I, D121H, K122E, D123S, I142V, F171Y, K173S, D177E, I202V, Q207A, R211S, F214LA
Vidal (2007)U222602BU.U2226AM260240NoneNone  I5V, K11T, V35T, E40D, S48T, K104R, V118I, K122E, D123S, S163T, T165I, K173L, Q174K, D177E, V179I, G196S, T200I, Q207A, R211N, F214L, V245K, E248D, A272P, V276I, T286A, E291D, I293V, P294T, E312D, G335D, R356K, M357K, R358K, G359S, A360T, A371V, I375V, A376V, T377M, A400T, T403M, E404N, K431T, E432D, V435AA
Nyombi (2008)TMS002TMS002EU251783NoneNone  K11Q, V35T, T39M, E40D, I50V, V60I, V118I, D121H, K122E, D123S, I135T, K173L, Q174K, D177E, T200A, Q207A, F214L, I244V, A272P, K277R, T286A, I293V, P294T, G335D, M357K, G359S, T369AA
Somi (2008)OY-05-514OY-05-514JQ616978NoneNone  E28K, K32E, V35T, V60I, V118I, K122E, D123S, I135T, S162A, K173S, Q174K, D177E, V179I, T200I, Q207A, R211S, F214L, V245Q, D250EA
Aghokeng (2009)CYV085CYV085GU191582NoneNone  K11R, V35I, T39A, V60I, V118I, D121H, K122E, D123S, I142V, T165I, D177E, V179I, G196GE, Q207A, R211S, F214L, V245Q, V261I, A272V, T286A, E291D, V292I, I293V, P294T, G335D, R356K, M357K, G359S, T369V, A371V, I375V, A376V, K390R, A400T, T403M, W410CA
 AV_0108AV_0108GU191649NoneNone  E6D, K11T, K20R, V35T, T39S, R72RG, V118I, D123N, I135T, K166R, K173T, D177E, G196E, Q207N, L210LF, R211K, F214L, V245Q, K275Q, V276I, T286A, I293V, P294T, R307K, I326V, G335DA
Vercauteren (2009)pt9597484273043GQ400065NoneNone  E6N, K11T, K22R, V35T, V118I, K122E, D123N, I135T, I142V, K166KR, K173S, Q174K, I202V, Q207A, R211S, F214L, V245Q, E248D, L283I, E291D, I293V, P294T, L295M, E297Q, E312D, I326VA
Yaotse (2009)HT07706TG.HT077FM955710NoneNone  P4S, K11T, V35T, E36A, T39K, K43E, V106I, V118I, D123N, I142V, S162Y, K173S, Q174K, D177E, I178L, V179I, T200A, Q207E, R211K, F214L, V245Q, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410H, E432DA
Balode (2010)S2011S2011GU945074NoneNone  K11T, V35IT, E36D, T39KQ, V118I, K122E, D123S, I142T, A158S, K173L, Q174K, Q207A, R211S, F214L, V245M, E248DA
Burda (2010)06LPH19CM06LPH19CMGQ344999NoneNone  E6K, K11V, L12S, V35T, E40D, K102Q, V118I, K122E, D123N, I135T, T139L, S162A, K173S, V179IA
Diop-Ndiaye (2010)114HALD114HALDFN599681NoneNone V179DK22R, E28A, V35T, T39A, V118I, D123N, I135T, I142V, T165I, E169N, K173T, Q174K, T200A, I202V, Q207A, R211K, F214L, V245Q, E248D, K281R, T286A, E291D, I293V, P294T, L295M, E297Q, K311R, Q334D, G335S, M357T, K390R, A400T, E404DA
Towler (2010)371850-K371850-KHM037863NoneNone  K11T, K20R, V21I, V35T, T39K, K43G, K49R, I50V, V60I, V118I, K122E, D123S, K173S, D177E, V179I, T200A, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, I293V, P294T, E312D, V317VAA
 385494-T385494-THM037866NoneNone  I5V, E6P, V35T, V60I, V118I, K122E, I135IT, I142IV, S162A, K173S, D177E, Q207E, F214L, V245E, D250E, V254I, D256DE, A272P, T286A, E291D, V292I, I293V, L303LM, E312TA
El Annaz (2011)291291HQ393324NoneNone  V35T, E36A, T39K, K43E, K64R, V118I, D121H, K122E, I135T, I142V, S162H, K173T, D177E, V179I, I195L, T200A, Q207A, F214LA
 1037510375HQ393383NoneNone  K30KN, V35T, E36EA, T39K, K43E, E53ED, N54NY, V60I, K64R, K102KQ, V118I, D121H, K122E, I135T, I142V, S162H, K173T, Q174QK, D177E, V179I, I195L, G196GE, T200TA, Q207A, F214L, V245QA
Fokam (2011)CIRCB-11689CIRCB-11689JQ796138NoneNone  E6N, K11T, V35T, T39TI, V118I, D123N, I142V, K173S, I178L, I202V, Q207A, R211RS, F214L, V245Q, E248D, S251T, A272P, V276I, T286A, E291ED, V292I, I293V, P294E, E297QA
Hamers (2011)CP076301533CP076301533HQ993577NoneNone  V35T, E40ED, V60I, V118I, D121H, K122E, I135IT, S162A, E169D, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L, D250E, A272P, T286A, I293V, P294T, E312D, D324DEA
 CP076301553CP076301553HQ993596NoneNone  V35T, E40ED, M41MT, V60I, V118I, D121H, K122E, I135IT, S162AD, E169D, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L, D250E, Y271F, A272S, I274G, K275Q, V276D, K277P, Q278F, T286A, I293V, P294T, E308V, I309F, E312D, D324E, L325I, G333S, Q334RA
 CP076301581CP076301581HQ993620NoneNone  E28A, K32Q, V35T, T39K, E40D, I50V, V60I, V118I, K122E, D123S, I135T, A158S, T165I, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245E, T286A, I293V, P294TA
 CP076302243CP076302243HQ993816NoneNone  E6D, V35T, E36D, T39TA, V60I, V118I, K122E, D123NS, I135T, Y144YF, Q145X, K173A, Q174K, D177E, V179I, T200A, Q207DE, R211K, F214FL, V245E, D250E, A272S, T286A, E291D, V292I, I293V, P294PT, E312N, S322AA
 CP076304180CP076304180HQ993894NoneNone  V35T, T39TIM, K43KR, V60I, V118I, D121H, K122E, I135T, K173LS, Q174K, D177E, I178V, T200A, Q207A, R211S, F214L, V245KM, E248D, D250E, S251SI, E291D, V292I, I293V, P294T, E312N, Q334H, G335DA
 CP076304265CP076304265HQ993953NoneNone  E6D, V35T, V60I, V118I, K122E, D123N, I135T, K173S, Q174K, V179I, T200A, Q207N, R211S, F214L, V245E, A272P, T286A, E291D, V292I, I293V, E312DA
 CP076300847CP076300847HQ995114NoneNone  E6D, K11Q, K20R, V35T, T39A, E40D, V60I, V118I, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, F214L, V245Q, E248D, T286A, E291D, I293V, P294TA
 CP076302054CP076302054HQ995204NoneNone  E6D, K11Q, K20R, V35T, T39A, E40D, V60I, V118I, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, F214L, V245Q, E248D, T286A, E291D, I293V, P294TA
 CP076300715CP076300715HQ995317NoneNone  K20R, V35T, E40D, V60I, V118I, D121H, K122E, I135T, E138A, K173A, Q174R, D177E, I178V, V179I, Q207A, R211S, V245K, A272P, K277R, T286A, E291D, V292I, I293V, P294TA
 CP076301897CP076301897HQ995376NoneNone  V35T, V60I, V118I, K122E, D123N, I135T, E138A, S162A, K173S, Q174K, V179I, T200A, Q207D, R211K, F214L, P243S, V245E, D250E, A272P, T286A, E291D, V292I, I293VA
 CP076301966CP076301966HQ995430NoneNone L234LIE6K, K11T, V35T, V60I, V118I, K122E, D123G, I135V, I142T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245Q, A272S, K275Q, K281R, T286A, E291D, I293V, P294TA
 CP076301977CP076301977HQ995440NoneNone  E6N, V35T, K43R, V60I, V118I, K122E, I135T, E138A, K173S, Q174K, I195K, T200A, Q207E, R211S, F214L, I244V, V245K, D250E, K277T, E291D, I293V, P294TA
 CP076302036CP076302036HQ995460NoneNone G190GRE6K, K20KR, V35T, E40ED, V60I, I63IV, V118I, K122E, I135T, E138A, S162A, T165X, K173S, Q174K, V179I, I202IV, Q207D, R211S, F214L, V245E, D250E, T286A, E291D, V292I, I293VA
Kasang (2011)1449714497HM572366NoneNoneK219KR V35T, G45GE, V60I, V118I, D121H, K122E, D123E, I135T, E138A, I142V, K173S, Q174K, V179I, T200A, Q207A, R211S, F214L, V245M, E248Q, D250E, A272T, T286A, E291D, V292I, I293V, P294T, E312DA
Ndembi (2011)NTCPS701NTCPS701HQ702669NoneNone  E6D, K20R, V35T, V60I, V118I, K122E, I135T, F160Y, S163T, T165I, K173A, Q174K, D177E, V179I, Q207A, R211K, F214LA
 AICPS164AICPS164HQ702671NoneNone  E6D, V35T, V60I, V118I, K122E, D123N, I135T, K173S, Q174K, D177E, I178V, T200A, Q207A, R211S, F214LA
Frange (2012)750733HML750733HMLJQ292414NoneNone  T39L, V60I, K64R, V118I, D121H, K122E, K173S, Q174K, D177E, T200A, Q207A, R211S, F214LA
 690206LKKF690206LKKFJQ292417NoneNone  T39A, M41T, K43Q, V60I, V118I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214LA
Sigaloff (2012)KEMGO613KEMGO613JN628532NoneNone  I2T, E6D, K11E, K20R, V35T, T39I, E40D, E42K, V60I, K104E, V118I, K122E, D123S, Q145W, K173L, Q174K, D177E, V179I, L193I, Q197K, R199G, T200A, Q207D, F214LA
Ssemwanga (2012)RCC_TDR_480631RCC_TDR_480631JQ266033NoneNone  V35T, T39A, E40D, K49R, V60I, V118I, K122R, I135T, Q145C, K173L, Q174K, D177E, V179T, Q207A, R211S, F214LA
 RCC_TDR_483515RCC_TDR_483515JQ266050NoneNone  V35T, T39A, E40D, V60I, V118I, I135T, Q145C, K173L, Q174K, D177E, V179T, T200A, Q207A, R211S, F214LA
Yang (2012)KN-45KN-45JQ616942NoneNone  K11Q, V35T, V60I, V118I, D121H, K122E, I135R, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245E, D250EA
Youngpairoj (2012)cm8bbcm8bbDQ166432NoneNone  E6N, V8I, K11T, V35T, E40D, V118I, D121H, K122E, D123S, I142V, F171Y, K173S, D177E, I202V, Q207A, R211S, F214L, V245Q, E248D, K275Q, V276I, R284K, T286A, V292I, I293V, P294T, L295M, E297Q, E312N, S322T, M357K, G359S, T369A, A371V, I375A, K390R, A400L, E432D, V435LA
Billong (2013)MR007MR007KF192218NoneNone  E6KN, K11T, V35T, V60VI, T69TS, V118I, K122E, D123NS, I135T, I142V, K173S, Q174K, D177E, I195L, T200TA, I202V, Q207A, R211S, F214L, V245Q, E248D, T286TA, E291D, V292VI, I293V, P294T, L295M, E297Q, E312D, A327AV, G335DA
Frentz (2013)EHR-14086EHR-14086JX299772NoneNone  V35T, E40D, I50V, V118I, K122E, D123DN, I135T, I142IT, T165I, K173S, Q174QR, V179VI, E194ED, T200TA, Q207A, R211S, F214L, V245LA
Hassan (2013)RS09000870RS09000870HQ441615NoneNone  K11T, K20R, V21I, V35T, T39K, V118I, K122E, D123N, I135T, K173S, D177E, V179I, G196R, I202V, Q207A, R211K, V245Q, E248MR, I270V, A272P, T286A, E291D, I293V, P294A, L295W, E312DA
 RS09000945RS09000945HQ441687NoneNone  K20KR, V35T, V60I, V118I, D121C, K122E, D123S, I135K, S162C, K173L, Q174K, D177E, T200A, Q207S, R211S, V245E, D250E, A272P, T286A, E291D, V292I, I293V, E312DA
 RS11000310RS11000310JQ698392NoneNone  E6K, K11T, V35T, E36D, T39A, E40D, V118I, K122E, D123N, I135T, K173A, D177E, V179I, V189I, Q207A, R211K, F214L, V245Q, D250E, V276I, Q278N, T286A, E291D, I293V, P294T, E312DA
Kemal (2013)73917391JQ364518NoneNone  V35T, E36A, V60I, V118I, K122E, I135T, T165I, K173S, V179I, T200A, Q207A, R211S, F214L, V245Q, A272P, T286P, E291D, I293V, P294T, L301F, G335D, M357K, G359S, T377M, T386A, K390R, A400T, T403M, E404DA
Masimba (2013)TZ.ET.38TZ.ET.38KC537207NoneNone  E29R, V35T, E40D, K43R, V60I, V118I, K122E, D123N, Q145QH, K173S, Q174K, D177E, V179I, Q207A, R211S, F214LA
 TZ59TZ59KC537158NoneNone  V60I, V118I, K122E, D123G, I135T, E138A, K173I, Q174K, D177G, T200A, Q207E, R211K, F214LA
 TZ.ET.42TZ.ET.42KC537219NoneNone  E29R, V35T, E36EA, E40D, V60I, V118I, K122E, D123N, I135T, K173A, Q174K, V179I, G196E, E203Q, Q207A, R211S, F214LA
 TZ154TZ154KC537100NoneNone  V35T, T39A, E40D, K49KR, P55PS, V60I, V118I, K122E, D123S, I135T, E138A, T139IV, K173A, Q174K, T200A, Q207A, R211RK, F214LA