<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation V118I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2002)130526d130526dAF410218AZTNone  P4H, K11T, V35T, E40D, K43R, I50V, V118I, K122E, D123S, I135R, K173S, D177E, V179I, I202V, Q207A, R211S, F214L, V245K, A272P, V276I, K277R, L282C, L283I, R284RK, T286A, A288T, V292I, I293V, E297AA
Vergne (2003)VL00SN69HPD00SN69AJ583752D4T, DDINoneM41L, M184V, T215Y K11T, V35T, T39A, V118I, K122E, D123N, I135T, K173S, Q174K, D177E, I178V, V179I, Q197E, Q207A, R211S, F214L, V245K, D250E, A272P, A288S, E291D, I293V, P294T, G335D, R356K, M357R, G359S, V365I, A371V, I375V, A376G, T377L, A400T, T403M, E404D, E432NA
Montes (2004)MB_patFEU02_FEU726AJ577889AZT, DDI, 3TC, D4TNoneM184V K11T, E28A, K32R, V35T, E40D, V60I, V118I, D121H, K122E, D123S, I135T, K173S, Q174R, D177E, I178L, V179I, T200A, Q207A, F214LA
Ndembi (2010)15460D_P115460GQ409574ABC, AZT, 3TCNoneD67N, K70R, M184V E6N, V35T, T39L, V60I, V118I, K122E, I135T, K173S, Q174K, D177E, V179I, T200K, Q207A, R211S, F214LA
 DT3513_05_P13513GQ409619ABC, AZT, 3TCNoneM184V, T215Y E6D, E28A, V35T, T39E, V60I, V118I, K122E, I135T, T139R, I142T, T165I, K173S, Q174K, V179I, T200A, Q207A, R211S, F214LA
Sigaloff (2011)HIV100812HIV100812JN132247ABC, AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YK103N, G190AK11T, V35T, T39E, E44D, K102R, V118I, K122E, D123N, I135T, K173L, Q174K, D177E, T200A, E203D, Q207A, R211N, V245Q, D250E, A272P, T286TP, E291D, V292I, I293VA
Kolomeets (2014)316316_419KJ870510AZT, 3TCNoneA62V, M184V K11T, V35I, E36D, T39K, V118I, K122E, D123S, I142IV, A158S, K173L, Q174K, D177E, T200I, E203D, Q207A, R211S, V245T, E248D, D250DNA
 177177_276KJ870397ABC, 3TCNoneA62V K11T, T39K, V118I, D123N, F214L, V245M, E248DA