<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation A98G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 36
Isolates 37
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL4567581585 AZT, DDI, 3TC, D4TNVPM184V, T215FA98G, Y181C, G190AK20R, V21I, V35T, K49KR, V60I, K101Q, K122E, D123S, I135V, K166R, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, S251I, A272P, K277R, E291D, V292I, E297A, L301M, D324E, I329VG
 PL865105515 DDC, AZT, 3TC, D4T, TDFEFVD67N, K70R, K219QA98G, K103N, Y188FLV35T, T39M, E40ED, K43KR, V60I, T69N, K122E, D123S, I135T, K173KR, Q174K, D177E, T200A, E203ED, Q207K, R211S, F214FL, K238KR, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, E300A, S322ST, D324E, I329VG
Weber (2005)M64940M64940AY677549AZT, D4T, 3TC, DDI, ABCNVPD67N, T69D, K70R, T215F, K219QA98GE6S, K11T, K20R, V35T, V60I, L109I, K122E, D123S, K173T, D177E, G196E, T200A, I202V, Q207E, R211K, L228H, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297T, D324EG
  M64940AY714452AZT, 3TC, D4T, DDI, ABCNVPD67N, T69D, K70R, L74V, M184V, K219QA98G, Y181C, G190AE6S, K11T, K20R, V35T, V60I, K122E, D123S, K173T, D177E, G196R, T200A, I202IV, Q207E, R211K, F214L, L228H, V245Q, E248D, D250E, A272P, E291D, V292VI, I293V, E297AT, I309IM, D324E, Q332QEG
Baxter (2006)48-12511251-30602DQ877776NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215YA98G, K101E, G190AE28K, K32E, V35T, T39A, E44D, V60I, V118I, K122E, I135V, S162C, K173T, Q174K, N175Y, D177E, T200A, E203D, Q207K, R211EK, K223Q, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, S379A, I382M, Q394R, K395RG
 48-31863186-30506DQ878094NRTINNRTIM41L, D67N, L74V, M184V, T215Y, K219NA98G, K103N, G190AV35T, T39A, E44D, V60I, V118I, K122E, D123S, K173R, Q174K, D177E, V179T, T200A, R206M, Q207E, L210S, R211K, T216M, L228H, Q242H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335D, F346Y, M357R, R358G, G359S, A371V, A376S, I382V, Q394K, E399DG
Gody (2008)Pt030Pt030 D4T, 3TCNVPM184VA98G, Y181CK20R, V35T, T39N, K49KR, V60I, K122E, I135T, T139R, I142V, K173T, D177E, T200A, Q207A, R211K, F214FL, V245M, A272P, T286A, E291D, V292I, I293V, E297A, E312DG
Hawkins (2009)P635ZZP635FJ931141D4T, 3TCNVPM41L, D67N, K70R, V75M, M184V, T215F, K219QA98G, K103N, Y181CI2V, V8VL, K20R, K32I, V35T, T39E, E40ED, V60I, S117A, V118I, K122E, I135R, E138Q, S162Y, K173T, Q174K, N175Y, D177E, T200A, Q207E, R211K, F214L, D218E, L228H, Q242H, V245Q, E248N, A272P, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, P294T, E297A, L301M, I329VG
 P640ZZP640FJ931145D4T, 3TCNVPK70R, M184V, K219QA98G, K103N, Y181CK20R, V35T, T39S, T69N, K122E, D123N, I135V, S162A, K173T, Q174K, N175NY, D177E, I178IM, T200A, Q207E, F214L, L228H, P243H, V245E, E248D, A272P, I274IV, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, S322TG
 P648ZZP648FJ931152D4T, 3TCNVPD67N, K70R, M184V, K219QA98G, K101E, G190AK20R, E28K, K32E, V35T, T39N, V60I, K122E, K166R, K173T, Q174N, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 P655ZZP655FJ931158D4T, 3TCNVPD67N, K70R, M184V, T215F, K219QA98G, Y188LK20R, V35T, T39Q, E40ED, V60VI, L109I, V118VI, K122E, D123N, K166R, F171Y, K173T, Q174E, D177E, I178M, T200A, I202V, E204EK, Q207E, F214L, V245Q, D250E, S251A, A272P, I274V, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, E297P, L301M, I329VG
 P878ZZP878FJ931167D4T, 3TCNVPM41L, T69D, M184V, T215YA98G, K101KE, Y181CK20R, V35T, K49R, V60I, D121H, K122E, I135IT, Q174N, D177DE, T200A, I202V, E203K, Q207D, R211K, K223E, L228R, V245KPQT, E248DN, D250DE, S251SN, A272P, T286A, E291D, V292I, I293V, P294SG
 P895ZZP895FJ931169D4T, 3TCNVPD67N, K70R, M184V, K219EQA98G, Y181CK20R, V35T, T39E, E40D, V60I, V106I, I135T, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, H221HY, V245K, E248D, D250E, A272PS, I274V, K275KR, Q278N, T286A, E291D, V292I, I293V, P294T, E297V, L301M, E312G, I329VG
 P923ZZP923FJ931181D4T, 3TCNVPM41L, D67N, K70R, V75VIM, M184V, L210W, T215Y, K219QA98G, Y181CFGV, G190GAK11KT, K20KR, V35T, T39TIM, E40ED, E44D, V60I, V118VI, D121H, K122E, D123DGNS, K173T, D177E, T200A, E203ED, Q207E, H208Y, R211K, D218E, L228H, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, P294T, S322T, I326VG
 P660ZZP660FJ931186D4T, 3TCNVPD67DN, T69TADN, K70R, V75I, M184V, K219QA98G, Y181CK20R, V35T, T39K, E40D, V60I, K104R, K122E, D123E, I132L, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, H221HY, L228LH, V245Q, E248D, D250E, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, I329VG
 P945ZZP945FJ931189D4T, 3TCNVPM41L, V75M, M184V, T215YA98G, K101KE, G190AV35T, V60I, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, I329VG
 Q223ZZQ223FJ931218D4T, 3TCNVPK70R, M184V, K219QA98G, Y181CK20KR, V21VI, V35T, E40D, K49R, V60I, T69N, K122E, D123NS, I135T, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214L, D218E, L228H, V245KLMQ, E248D, D250K, A272P, T286A, E291D, V292VI, I293V, K311KR, I329VG
 Q198ZZQ198FJ931227D4T, 3TCNVPM184V, T215YA98G, K101E, Y181CV21I, V35T, V60I, K122E, D123S, I135T, T165L, K173A, Q174K, D177E, I178M, G196E, T200A, Q207E, V241I, V245Q, E248D, D250E, S251N, A272S, T286A, E291D, V292I, I293V, K311KR, D324E, I329VG
 Q840ZZQ840FJ931237D4T, 3TCNVPD67DN, K70R, M184V, K219EA98G, Y181CK20R, V35T, T39K, E40D, V60I, K122E, I142V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, F214L, L228H, V245Q, E248D, D250E, S251H, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, E328D, I329VG
 R57ZZR57FJ931298TDF, 3TCNVPK70E, M184VA98G, Y181CV35T, K122E, D123S, I135M, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, L228R, V245Q, E248D, D250E, A272P, Q278H, E291D, V292I, I293V, D324E, I329VG
 R63ZZR63FJ931301AZT, 3TCNVPM41L, M184V, T215YA98G, Y181CV35T, K43Q, E44ED, V60I, K122P, D123S, I135V, T139R, S162A, K166KR, Q174N, D177E, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E300Q, I329VG
 Q969ZZQ969FJ931304D4T, 3TCNVPM184V, T215YA98G, V179E, Y181CK20R, V35T, T39K, K103R, K122E, K173T, Q174K, D177E, E194D, G196E, T200A, Q207E, R211K, H221HY, P243S, V245Q, E248D, D250E, S251N, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 Q949ZZQ949FJ931323D4T, 3TCNVPM41L, M184V, T215FYA98G, K101E, G190AE28K, V35T, V60I, K173T, Q174K, D177E, I178M, T200A, Q207D, V245Q, S251N, A272S, T286A, E291D, V292I, I293V, K311R, E312K, D324E, I329VG
 R127ZZR127FJ931334TDF, 3TCEFV, NVPK65R, M184V, K219KEA98G, V108I, V179E, Y181C, M230LP4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329VG
 R153ZZR153FJ931348D4T, 3TCNVPK70KR, M184V, T215TFISA98G, V108VI, Y181CP4S, K20R, V35T, V60I, R83RK, V90I, K122E, I135V, T139TR, S162A, K173T, Q174K, T200A, Q207E, R211K, F214FL, V245Q, A272P, T286A, E291D, I293V, E297A, L301MG
 R349ZZR349FJ931376NRTINVPM41ML, M184V, T215YA98G, V108VI, Y181CK20R, V35T, K49R, I50V, K101KQ, K122A, D123S, K173T, Q174R, D177E, I178L, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297K, K311R, I329VG
 R229ZZR229FJ931386NRTINVPM184VA98G, K101KE, V108VI, Y181CV35T, E40D, K49KR, V60I, D121H, K122E, I135T, K173T, Q174K, D177E, I178L, I195IL, T200A, E203D, Q207N, D218DE, H221HY, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, K311KRG
 R250ZZR250FJ931395AZT, 3TCNVPM41L, D67DN, K70KR, M184V, T215FA98G, Y181C, G190AV35T, T39A, E44ED, K49R, V60I, V90VI, I94L, K104R, K122E, D123N, I132V, S162N, F171Y, K173T, Q174N, D177E, I178M, T200A, I202V, Q207E, R211K, F214L, H221Y, V245K, E248D, D250E, S251V, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R256ZZR256FJ931401AZT, 3TCNVPD67N, K70R, M184V, K219QA98G, G190AV35T, K49R, V60I, K122E, D123T, Q174N, D177E, T200A, Q207E, R211K, D218E, P243S, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, K311R, I329IVG
 R257ZZR257FJ931402AZT, 3TCNVPM41L, M184V, L210LW, T215FA98G, K103NV8VI, V35T, V60I, V90I, K122E, D123S, I135T, E138Q, S162Y, Q174N, D177E, I178L, G196GE, T200A, Q207D, V245Q, E248D, D250E, A272P, V276VI, T286A, E291D, V292I, I293V, D324EG
 R366ZZR366FJ931404D4T, 3TCEFV, NVPD67DN, K70R, M184V, K219EA98G, Y181C, G190GAV35T, T39L, V60I, W88C, K104R, V118VI, D121Y, K122E, D123DEKN, I135IT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251D, A272P, K275R, T286A, E291D, V292I, I293V, E297K, E312GG
 R367ZZR367FJ931405D4T, 3TCEFV, NVPM184V, T215YA98G, K101E, V108VI, Y181C, G190AK20R, E28K, K32KE, V35T, K49R, V60I, K104R, K122E, I135V, T139TI, K173IM, Q174K, D177E, T200A, Q207G, R211K, V241VI, V245Q, E248D, D250E, S251I, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I309IM, S322SA, I329VG
 R239ZZR239FJ931433AZT, 3TCNVPM41ML, D67N, K70R, M184V, T215F, K219EA98G, K101E, Y181C, G190AE28EK, V35T, V60I, T69N, K104R, K122E, D123N, K173T, Q174R, D177E, T200A, I202V, Q207E, F214L, L228H, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R472ZZR472FJ931435D4T, 3TCNVPD67G, K70KR, M184V, K219KEA98G, V106AK20R, V35T, V60VI, S68G, S105V, D121H, K122E, I135L, K173T, Q174R, D177E, I178L, T200A, Q207E, F214L, V245Q, E248D, D250K, S251D, A272P, K277R, Q278H, K281R, T286A, V292I, I293V, E297A, L301M, P321S, S322E, D324E, E328D, I329VG
 R269ZZR269FJ931445TDF, AZT, D4T, 3TCNVPK70R, M184V, K219QA98G, V108I, Y181CV35T, V60I, K122E, D123N, I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, F214L, D218E, L228R, Q242QK, V245HQ, E248N, D250E, S251H, A272P, T286A, E291D, V292I, I293V, K311R, I329VG
 R443ZZR443FJ931454NRTINVPM184VA98G, K101E, E138KQR, G190AV21VI, V35T, T39IM, E40D, V60I, W88WC, K104R, K122E, D123S, I132IV, I135T, K173T, Q174K, V179I, T200A, I202V, Q207D, R211K, F214L, V245Q, D250E, S251H, A272P, T286A, E291D, V292I, I293V, E297K, S322G, D324EG
Charpentier (2011)125CP 001 949 D4T, 3TCNVPM184VA98G, K101E, G190AV35T, T39N, E40D, V60I, K104R, K122E, D123N, I135V, I142V, K173T, D177E, T200A, Q207A, R211K, D237DE, V245Q, E248N, A272P, K281R, E291D, V292I, I293V, E297A, E312N, V317A, P321S, D324E, I329V, Q334EG