<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation A98G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 17
Patients 111
Isolates 112
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL4567581585 AZT, DDI, 3TC, D4TNVPM184V, T215FA98G, Y181C, G190AK20R, V21I, V35T, K49KR, V60I, K101Q, K122E, D123S, I135V, K166R, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, S251I, A272P, K277R, E291D, V292I, E297A, L301M, D324E, I329VG
 PL865105515 DDC, AZT, 3TC, D4T, TDFEFVD67N, K70R, K219QA98G, K103N, Y188FLV35T, T39M, E40ED, K43KR, V60I, T69N, K122E, D123S, I135T, K173KR, Q174K, D177E, T200A, E203ED, Q207K, R211S, F214FL, K238KR, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, E300A, S322ST, D324E, I329VG
Weber (2005)M64940M64940AY677549AZT, D4T, 3TC, DDI, ABCNVPD67N, T69D, K70R, T215F, K219QA98GE6S, K11T, K20R, V35T, V60I, L109I, K122E, D123S, K173T, D177E, G196E, T200A, I202V, Q207E, R211K, L228H, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297T, D324EG
  M64940AY714452AZT, 3TC, D4T, DDI, ABCNVPD67N, T69D, K70R, L74V, M184V, K219QA98G, Y181C, G190AE6S, K11T, K20R, V35T, V60I, K122E, D123S, K173T, D177E, G196R, T200A, I202IV, Q207E, R211K, F214L, L228H, V245Q, E248D, D250E, A272P, E291D, V292VI, I293V, E297AT, I309IM, D324E, Q332QEG
Baxter (2006)48-12511251-30602DQ877776NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215YA98G, K101E, G190AE28K, K32E, V35T, T39A, E44D, V60I, V118I, K122E, I135V, S162C, K173T, Q174K, N175Y, D177E, T200A, E203D, Q207K, R211EK, K223Q, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, S379A, I382M, Q394R, K395RG
 48-31863186-30506DQ878094NRTINNRTIM41L, D67N, L74V, M184V, T215Y, K219NA98G, K103N, G190AV35T, T39A, E44D, V60I, V118I, K122E, D123S, K173R, Q174K, D177E, V179T, T200A, R206M, Q207E, L210S, R211K, T216M, L228H, Q242H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335D, F346Y, M357R, R358G, G359S, A371V, A376S, I382V, Q394K, E399DG
Hawkins (2009)P635ZZP635FJ931141D4T, 3TCNVPM41L, D67N, K70R, V75M, M184V, T215F, K219QA98G, K103N, Y181CI2V, V8VL, K20R, K32I, V35T, T39E, E40ED, V60I, S117A, V118I, K122E, I135R, E138Q, S162Y, K173T, Q174K, N175Y, D177E, T200A, Q207E, R211K, F214L, D218E, L228H, Q242H, V245Q, E248N, A272P, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, P294T, E297A, L301M, I329VG
 P648ZZP648FJ931152D4T, 3TCNVPD67N, K70R, M184V, K219QA98G, K101E, G190AK20R, E28K, K32E, V35T, T39N, V60I, K122E, K166R, K173T, Q174N, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 P655ZZP655FJ931158D4T, 3TCNVPD67N, K70R, M184V, T215F, K219QA98G, Y188LK20R, V35T, T39Q, E40ED, V60VI, L109I, V118VI, K122E, D123N, K166R, F171Y, K173T, Q174E, D177E, I178M, T200A, I202V, E204EK, Q207E, F214L, V245Q, D250E, S251A, A272P, I274V, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, E297P, L301M, I329VG
 P878ZZP878FJ931167D4T, 3TCNVPM41L, T69D, M184V, T215YA98G, K101KE, Y181CK20R, V35T, K49R, V60I, D121H, K122E, I135IT, Q174N, D177DE, T200A, I202V, E203K, Q207D, R211K, K223E, L228R, V245KPQT, E248DN, D250DE, S251SN, A272P, T286A, E291D, V292I, I293V, P294SG
 P895ZZP895FJ931169D4T, 3TCNVPD67N, K70R, M184V, K219EQA98G, Y181CK20R, V35T, T39E, E40D, V60I, V106I, I135T, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, H221HY, V245K, E248D, D250E, A272PS, I274V, K275KR, Q278N, T286A, E291D, V292I, I293V, P294T, E297V, L301M, E312G, I329VG
 P923ZZP923FJ931181D4T, 3TCNVPM41L, D67N, K70R, V75VIM, M184V, L210W, T215Y, K219QA98G, Y181CFGV, G190GAK11KT, K20KR, V35T, T39TIM, E40ED, E44D, V60I, V118VI, D121H, K122E, D123DGNS, K173T, D177E, T200A, E203ED, Q207E, H208Y, R211K, D218E, L228H, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, P294T, S322T, I326VG
 P660ZZP660FJ931186D4T, 3TCNVPD67DN, T69TADN, K70R, V75I, M184V, K219QA98G, Y181CK20R, V35T, T39K, E40D, V60I, K104R, K122E, D123E, I132L, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, H221HY, L228LH, V245Q, E248D, D250E, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, I329VG
 P945ZZP945FJ931189D4T, 3TCNVPM41L, V75M, M184V, T215YA98G, K101KE, G190AV35T, V60I, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, I329VG
 Q223ZZQ223FJ931218D4T, 3TCNVPK70R, M184V, K219QA98G, Y181CK20KR, V21VI, V35T, E40D, K49R, V60I, T69N, K122E, D123NS, I135T, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214L, D218E, L228H, V245KLMQ, E248D, D250K, A272P, T286A, E291D, V292VI, I293V, K311KR, I329VG
 Q198ZZQ198FJ931227D4T, 3TCNVPM184V, T215YA98G, K101E, Y181CV21I, V35T, V60I, K122E, D123S, I135T, T165L, K173A, Q174K, D177E, I178M, G196E, T200A, Q207E, V241I, V245Q, E248D, D250E, S251N, A272S, T286A, E291D, V292I, I293V, K311KR, D324E, I329VG
 Q840ZZQ840FJ931237D4T, 3TCNVPD67DN, K70R, M184V, K219EA98G, Y181CK20R, V35T, T39K, E40D, V60I, K122E, I142V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, F214L, L228H, V245Q, E248D, D250E, S251H, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, E328D, I329VG
 R57ZZR57FJ931298TDF, 3TCNVPK70E, M184VA98G, Y181CV35T, K122E, D123S, I135M, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, L228R, V245Q, E248D, D250E, A272P, Q278H, E291D, V292I, I293V, D324E, I329VG
 R63ZZR63FJ931301AZT, 3TCNVPM41L, M184V, T215YA98G, Y181CV35T, K43Q, E44ED, V60I, K122P, D123S, I135V, T139R, S162A, K166KR, Q174N, D177E, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E300Q, I329VG
 Q969ZZQ969FJ931304D4T, 3TCNVPM184V, T215YA98G, V179E, Y181CK20R, V35T, T39K, K103R, K122E, K173T, Q174K, D177E, E194D, G196E, T200A, Q207E, R211K, H221HY, P243S, V245Q, E248D, D250E, S251N, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 Q949ZZQ949FJ931323D4T, 3TCNVPM41L, M184V, T215FYA98G, K101E, G190AE28K, V35T, V60I, K173T, Q174K, D177E, I178M, T200A, Q207D, V245Q, S251N, A272S, T286A, E291D, V292I, I293V, K311R, E312K, D324E, I329VG
 R127ZZR127FJ931334TDF, 3TCEFV, NVPK65R, M184V, K219KEA98G, V108I, V179E, Y181C, M230LP4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329VG
 R153ZZR153FJ931348D4T, 3TCNVPK70KR, M184V, T215TFISA98G, V108VI, Y181CP4S, K20R, V35T, V60I, R83RK, V90I, K122E, I135V, T139TR, S162A, K173T, Q174K, T200A, Q207E, R211K, F214FL, V245Q, A272P, T286A, E291D, I293V, E297A, L301MG
 R349ZZR349FJ931376NRTINVPM41ML, M184V, T215YA98G, V108VI, Y181CK20R, V35T, K49R, I50V, K101KQ, K122A, D123S, K173T, Q174R, D177E, I178L, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297K, K311R, I329VG
 R229ZZR229FJ931386NRTINVPM184VA98G, K101KE, V108VI, Y181CV35T, E40D, K49KR, V60I, D121H, K122E, I135T, K173T, Q174K, D177E, I178L, I195IL, T200A, E203D, Q207N, D218DE, H221HY, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, K311KRG
 R250ZZR250FJ931395AZT, 3TCNVPM41L, D67DN, K70KR, M184V, T215FA98G, Y181C, G190AV35T, T39A, E44ED, K49R, V60I, V90VI, I94L, K104R, K122E, D123N, I132V, S162N, F171Y, K173T, Q174N, D177E, I178M, T200A, I202V, Q207E, R211K, F214L, H221Y, V245K, E248D, D250E, S251V, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R256ZZR256FJ931401AZT, 3TCNVPD67N, K70R, M184V, K219QA98G, G190AV35T, K49R, V60I, K122E, D123T, Q174N, D177E, T200A, Q207E, R211K, D218E, P243S, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, K311R, I329IVG
 R257ZZR257FJ931402AZT, 3TCNVPM41L, M184V, L210LW, T215FA98G, K103NV8VI, V35T, V60I, V90I, K122E, D123S, I135T, E138Q, S162Y, Q174N, D177E, I178L, G196GE, T200A, Q207D, V245Q, E248D, D250E, A272P, V276VI, T286A, E291D, V292I, I293V, D324EG
 R366ZZR366FJ931404D4T, 3TCEFV, NVPD67DN, K70R, M184V, K219EA98G, Y181C, G190GAV35T, T39L, V60I, W88C, K104R, V118VI, D121Y, K122E, D123DEKN, I135IT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251D, A272P, K275R, T286A, E291D, V292I, I293V, E297K, E312GG
 R367ZZR367FJ931405D4T, 3TCEFV, NVPM184V, T215YA98G, K101E, V108VI, Y181C, G190AK20R, E28K, K32KE, V35T, K49R, V60I, K104R, K122E, I135V, T139TI, K173IM, Q174K, D177E, T200A, Q207G, R211K, V241VI, V245Q, E248D, D250E, S251I, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I309IM, S322SA, I329VG
 R239ZZR239FJ931433AZT, 3TCNVPM41ML, D67N, K70R, M184V, T215F, K219EA98G, K101E, Y181C, G190AE28EK, V35T, V60I, T69N, K104R, K122E, D123N, K173T, Q174R, D177E, T200A, I202V, Q207E, F214L, L228H, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R472ZZR472FJ931435D4T, 3TCNVPD67G, K70KR, M184V, K219KEA98G, V106AK20R, V35T, V60VI, S68G, S105V, D121H, K122E, I135L, K173T, Q174R, D177E, I178L, T200A, Q207E, F214L, V245Q, E248D, D250K, S251D, A272P, K277R, Q278H, K281R, T286A, V292I, I293V, E297A, L301M, P321S, S322E, D324E, E328D, I329VG
 R269ZZR269FJ931445TDF, AZT, D4T, 3TCNVPK70R, M184V, K219QA98G, V108I, Y181CV35T, V60I, K122E, D123N, I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, F214L, D218E, L228R, Q242QK, V245HQ, E248N, D250E, S251H, A272P, T286A, E291D, V292I, I293V, K311R, I329VG
 R443ZZR443FJ931454NRTINVPM184VA98G, K101E, E138KQR, G190AV21VI, V35T, T39IM, E40D, V60I, W88WC, K104R, K122E, D123S, I132IV, I135T, K173T, Q174K, V179I, T200A, I202V, Q207D, R211K, F214L, V245Q, D250E, S251H, A272P, T286A, E291D, V292I, I293V, E297K, S322G, D324EG
Sigaloff (2011)HIV102901HIV102901JN132317AZT, 3TCNVPM41L, D67N, T69D, M184V, T215YA98G, K103NV35T, T39D, E44D, S48T, V60I, K122E, I135L, K173T, Q174N, D177E, I178M, T200A, Q207E, V245Q, E248D, D250E, A272P, K275R, K277R, Q278N, T286A, E291D, V292I, I293VG
 HIV105126HIV105126JN132365AZT, 3TCNVPM41L, D67DG, T69D, K70R, M184V, T215F, K219QA98G, V179E, Y181C, M230LV35T, T39A, V60I, K102Q, K122E, D123G, K173T, Q174K, D177E, I178M, T200A, Q207N, D218E, L228H, Q242H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293VG
 HIV105202HIV105202JN132377AZT, 3TCEFVM41L, M184V, L210W, T215YA98G, Y188LV35T, T39N, E44G, I47X, S48T, K122E, D123S, S162C, K173T, Q174KR, D177E, I178M, V189VI, T200A, E203EK, Q207D, R211K, L228R, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E312QG
Fourati (2012)83402898340289JQ396169NRTINNRTIM41L, D67N, L74V, M184V, T215Y, K219NA98G, K103N, Y181C, G190AV35T, T39A, E44D, V60I, K64R, V118I, K122E, D123S, I135T, E138Q, K173R, Q174K, D177E, V179T, T200A, E203G, R206M, Q207E, L210S, R211K, T216M, L228HG
 93904219390421JQ395794NRTINNRTIM41ML, T215SYA98G, V179VEV21I, V35T, V60I, K122E, D123N, K173IR, Q174K, D177K, T200A, Q207EG
Hamers (2012)CP076306483CP076306483JQ480198TDF, FTCNVPK70E, Y115F, M184VA98G, Y181CK20R, V35T, T39K, V60I, T69N, K101R, D121H, K122E, F171Y, K173T, Q174KR, D177E, I178M, T200A, Q207E, R211K, L228LR, V245HQ, E248D, D250E, S251HQ, A272P, Q278H, T286A, E291D, V292I, I293V, P294T, E297AV, L301M, D324E, I329VG
 CP076306495CP076306495JQ480200AZT, 3TCNVPM184VA98G, K101E, G190AE28EK, V35T, T39L, V60I, D123N, I135V, E169D, K173T, Q174K, D177E, T200A, Q207D, R211K, F214L, V245Q, E248N, D250E, T286A, E291D, I293VG
Kouri (2012)CU1342-10CU1342-10JQ585425NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215YA98G, V108VI, Y181CP9PS, V35T, E44D, V60I, K64R, V118I, K122E, I135V, K173I, Q174K, D177E, I178IM, I195L, T200A, E203K, H208Y, R211D, K223E, V245Q, E248D, D250E, A272P, G273GE, T286A, E291D, V292I, I293V, P294T, E297A, D324E, I329VG
Ugbena (2012)2-1162-2-116 TDF, FTCNVPM184MVA98G, Y181CV35T, K122E, D123S, I135IT, I142IV, S162C, P170PS, K173A, Q174K, D177E, I178L, T200A, Q207N, H221Y, V245Q, D250EG
 2-1282-2-128 TDF, FTCNVPM184VA98G, V108VI, Y181CV35T, K49KR, V60I, K101KQ, D121H, K122E, I132IV, I135IM, S162X, K173T, Q174K, D177E, I178L, T200A, K201KR, I202IV, Q207D, R211K, H221HY, L228LR, V245Q, E248D, D250EG
Etiebet (2013)9993407NG.SN225HQ843637TDF, FTCNVPK70Q, M184VA98G, Y181CV35T, V60I, K122E, D123S, I142V, K166R, K173I, Q174K, D177E, T200A, I202IV, Q207A, R211K, H221Y, L228LCFRG
Pircher (2013)B1115B1115JX110216D4T, 3TC, AZTNVPM41L, D67G, M184V, T215FA98G, V108I, Y181C, G190AP4S, E6D, L34I, V35T, T39L, E44D, V60I, S68G, K102Q, K122E, D123S, I135T, S162Y, K173T, Q174N, S191SF, I195L, T200A, E203A, Q207E, R211K, F214L, D218E, K219G, H221Y, V245QG
 B1106B1106JX110208D4T, 3TC, AZTNVPM41L, D67N, M184V, L210W, T215YA98G, Y181CV35T, T39N, E44D, K122E, D123S, I135T, K173R, Q174N, D177E, I178M, T200A, E203K, Q207D, R211K, H221Y, V245T, E248D, D250E, L260VG
 B1112B1112JX110213D4T, 3TC, AZTNVPK70E, M184VA98G, V179E, G190SK20R, K22R, V35T, E36K, T39D, E40D, V60I, W88C, K102Q, K122P, E138A, T139V, K173T, Q174K, D177E, T200A, E203K, Q207E, F214L, V245QG
Rawizza (2013)LL2169LL2169KF241466NRTINNRTIM184V, T215YA98G, K103NK20R, V35T, E40D, K49R, V60I, S68G, K102KR, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, S251N, A272P, T286A, E291D, V292I, I293V, I329VG
 PJ6749PJ6749KF241460NRTINNRTIM41L, M184V, L210W, T215YA98G, Y181C, G190AV21I, V35T, E44D, T69N, W88C, V111I, V118I, K122E, K173A, Q174K, D177E, T200A, E203K, Q207D, H208Y, R211RK, K223E, L228R, P243PS, V245Q, E248D, A272S, T286A, A288S, V292I, I293V, I329VG
 PJ8953PJ8953KF241508NRTINNRTIM41L, D67DG, T69S_EA, M184V, T215YA98G, K103NV35T, E44ED, V60I, I94IL, V118VI, K122E, D123S, I132V, K173T, Q174K, D177E, I178L, T200A, Q207N, L210LS, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297EKG
 LL3229LL3229KF241463NRTINNRTIM41L, D67N, K70R, M184V, T215F, K219EA98G, K103NK20R, V35T, V60I, K122E, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, E297KG
 PJ9611PJ9611KF241501NRTINNRTIM41L, M184V, T215YA98G, K103KN, V108VIV35T, V60I, L109LI, D121HY, K122E, I135T, K173T, Q174R, D177E, T200A, I202V, Q207D, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I329VG
Theys (2013)42674267KC219352TDF, FTCNVPK70E, M184VA98G, Y181C, G190AV60I, K122E, D123N, I135V, T165I, K173A, Q174K, D177E, I178M, V189I, Q197E, T200A, I202V, E203EK, Q207EK, R211KG
 26782678KC219189NRTI, TDFNNRTIM41L, D67DN, L74LV, T215Y, K219KNA98G, K103KN, Y181CE44ED, K122E, D123S, K173T, Q174K, D177E, I178LM, T200TA, Q207E, R211K, D218DEG
 2567825678KC220366NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 5610056100KC221753NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 44594459KC219368NRTI, TDFNNRTID67N, K70R, K219QA98G, K103N, Y181C, G190AE40D, K43R, V60I, T69N, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, E203D, Q207K, R211S, F214L, L228HG
 4665746657KC221362NRTI, TDFNNRTIM41L, D67N, M184V, T215Y, K219QA98GE40D, V60I, K122E, D123N, I135L, K173Q, Q174K, D177E, I178M, I195L, G196E, T200A, E203K, Q207EG
Aghokeng (2014)TG-2-292TG-2-292KC350205NRTINNRTIM184VA98G, V106A, F227LK20R, V35T, V60I, S105I, D121Y, K122E, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, P294S, E297V, L301M, I329V, Q334L, G335D, F346Y, M357K, R358G, G359S, A360P, V365I, A371V, S379G, T386I, Q394R, A400VG
 TG-2-080TG-2-080KC350208NRTINNRTIV75I, M184VA98G, Y181CV35T, T39N, E40D, V60I, R78RK, D121H, K122E, I132L, I135V, S162C, K173RT, Q174K, D177E, I178IL, T200A, Q207E, R211K, H221Y, V245Q, D250E, A272P, K275KR, Q278H, K281R, T286A, E291D, V292I, I293V, P294PS, E297V, L301M, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V365I, T386I, Q394R, E399D, A400IG
Konou (2015)H1609H1609KT316096NRTINNRTID67N, K70R, M184V, T215F, K219QA98G, Y181CK20R, V35T, T39Q, E40D, T69TN, K104KR, I135T, K173T, Q174R, D177E, T200A, I202V, Q207E, R211K, F214L, H221Y, V245Q, E248D, D250EG
 H337H337KT316067NRTINNRTIM41L, M184V, L210W, T215YA98G, Y181CK20R, V35T, E36EA, T39K, K43E, E44D, K49R, I94IL, K122E, D123S, I135L, S162C, K173S, Q174K, D177E, I178L, T200A, E203EK, Q207E, R211K, H221Y, V245Q, E248D, D250EG
 H462H462KT316064NRTINNRTIK70E, M184VA98G, K103N, V108I, Y181CK20R, V35T, V60I, K122E, D123N, I135IV, S163ST, K173T, Q174K, D177E, I178M, V189VI, T200A, Q207E, R211K, H221Y, P243T, V245QG
 H832H832KT316047NRTINNRTIM41L, M184V, L210W, T215YA98G, V108I, V179E, Y181CK20R, V21I, E28E*, V35T, T39A, E44D, V60I, K102Q, K103R, L109I, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, D218EG
Lam (2016)2101200221012002KR867756AZT, 3TCNVPM41L, A62V, V75I, M184V, T215YA98G, K103NI31L, V35T, K122E, D123S, I135IT, K173LV, Q174K, D177E, I178L, T200A, R211K, V245Q, D250E, S251D, A272P, K275KQ, K277R, T286A, E291D, V292I, I293V, P294T, A327V, Q334HL, G335DG
 2103200121032001KR867796AZT, 3TCNVPM41L, V75I, M184V, T215YA98G, K103NV35T, T39A, V60I, T69TA, K101KR, K122E, D123N, I132L, I135M, K173T, Q174K, N175NY, D177E, I178M, T200A, K201KR, I202V, Q207E, V245Q, E248N, D250E, A272P, Q278N, T286A, E291D, V292I, I293V, D324E, I329V, Q334P, G335DG
 2103100321031003KR868223TDF, FTCNVPK65R, Y115F, M184VA98G, Y181CP4S, E6D, K20R, V35T, T39K, E40ED, V60I, K104R, K122E, D123S, I132V, S162Y, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, E248N, D250E, A272P, K275Q, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, S322ST, I329V, Q334L, G335DG
 2103201621032016KR867764AZT, 3TCEFVM41ML, K70KR, M184VA98G, K103N, P225HE6EK, K20KR, V35T, V60I, K104R, K122E, D123S, I135L, K173A, Q174K, D177E, T200V, I202IV, Q207E, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, S322A, D324E, I329V, Q334C, G335DG
 2103200521032005KR867737TDF, FTCNVPA62AV, K65R, Y115YF, M184VA98G, Y181CV35T, T39A, K43KR, K46Q, S68N, R83K, V90I, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207E, R211K, V245Q, E248D, D250E, S251D, A272P, K281R, T286A, E291D, V292I, I293V, I329V, Q334L, G335DG
 2101200821012008KR868135AZT, 3TCNVPM41L, M184V, L210W, T215YA98G, K103NK32I, V35K, T39A, E44D, V60I, I135L, Q174N, D177E, I178M, T200A, Q207N, H208HY, R211K, L228LH, V245Q, D250E, V254I, A272P, T286A, I293V, E297R, I329VG
 2103201921032019KR868129TDF, FTCNVPD67N, K70R, M184V, K219QA98G, V179E, Y181CK20R, V35T, T39K, E40D, V60I, K103R, K122A, T139M, S162A, K173T, Q174R, D177E, T200A, E203K, R206K, Q207E, R211K, F214L, D218E, K223E, V245Q, E248D, D250E, S251N, A272P, K275Q, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V, Q334P, G335DG
 2101202021012020KR867980TDF, FTCNVPK70E, M184VA98G, Y181CK32KRT, V35T, V60I, K101Q, K122E, D123E, Q174R, D177E, I178M, G196GE, T200A, Q207D, R211RK, H221Y, L228R, V245Q, E248N, K249KQ, D250E, A272P, K275KR, K277R, T286A, E291D, V292I, I293V, V314A, S322TG
 2101100621011006KR868128TDF, FTCNVPK70R, M184V, K219EA98G, K103N, Y181CK20R, V35T, V60I, K122P, I135T, T165I, K173T, Q174K, T200A, R211K, F214L, L228R, V245Q, E248D, D250E, S251D, A272P, I274V, Q278H, K281R, L283I, T286A, E291D, V292I, I293V, E297AV, L301M, I329V, Q334P, G335DG
 2103201821032018KR868031TDF, FTCNVPK65R, M184VA98G, V108I, Y181CV35T, S68G, K122E, I135T, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248EDKN, D250E, A272P, E291D, I293V, D324E, I329V, Q334LP, G335DG
 2101200521012005KR867757TDF, FTCNVPM41L, K70E, M184V, T215FA98G, Y181CK20R, V35T, V60I, D121Y, K122E, T139K, K173T, Q174K, D177E, I178L, T200A, I202V, Q207D, V245Q, E248N, D250E, S251D, A272P, T286A, E291D, V292I, I293V, P294Q, Q334P, G335DG
Chaplin (2017)NJIH0381NJIH0381MF622932NRTINNRTIM41L, M184V, L210W, T215YA98G, K103N, K238KTK20R, V35T, T39K, V60I, S68SG, D121H, K122E, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, V245Q, D250E, S251N, A272P, K275R, K277R, Q278H, K281KR, T286A, E291D, V292I, I293V, P294S, E297A, L301M, S322T, G335DG
 NJIH0374NJIH0374MF622925NRTINNRTIM184VA98G, V179E, Y188WK20R, V35T, T39E, V60I, K64R, K102Q, D121Y, K122E, E138G, K173A, Q174K, T200A, Q207E, R211K, F214L, D237N, V245Q, E248D, D250EG
 NJIH0373NJIH0373MF622924NRTINNRTIM184VA98G, V106VM, V179E, Y188YCK20R, E28A, V35T, T39E, V60I, K64R, K102Q, D121Y, K122E, E138G, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335DG
 NJIH0340NJIH0340MF622891NRTINNRTID67N, K70R, M184V, K219QA98G, Y181CV35T, V60I, V118I, K122E, I135V, T139R, K173T, Q174R, D177E, I178L, T200E, E203K, Q207D, R211K, F214L, V245Q, E248DG
 NJIH0339NJIH0339MF622890NRTINNRTID67DN, K70KR, M184V, K219KQA98G, Y181CV35T, V60I, V118VI, K122KE, I135V, T139R, K173T, Q174R, D177E, I178L, T200E, E203K, Q207D, R211K, F214FL, V245Q, E248X, D250DE, A272P, T286TA, E291D, I293V, D324DE, Q334L, G335DG
 NJIH0324NJIH0324MF622875NRTINNRTIM184VA98G, K103NK20R, V35T, T39K, E40D, K43Q, S48T, V60I, D123E, T139K, S162A, K173T, Q174K, I178V, T200A, Q207E, R211K, F214L, V245T, E248X, D250DNG
 NJIH0323NJIH0323MF622874NRTINNRTIM184VA98G, K103NK20R, V35T, T39K, E40D, K43Q, S48T, V60I, D123E, T139TK, S162A, K173T, Q174K, I178V, T200A, Q207E, R211K, F214L, V245T, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335DG
 NJIH0278NJIH0278MF622829NRTINNRTIM184VA98G, K103S, G190AV35T, T39L, V60I, I135V, K173T, Q174K, D177E, T200A, I202V, Q207D, V245Q, D250E, S251DG
 NJIH0277NJIH0277MF622828NRTINNRTIM184VA98G, K101KE, Y181YC, G190AV35T, T39L, V60VI, I135V, K173T, Q174K, D177E, T200A, I202V, E203EK, Q207D, V245Q, E248ED, D250E, S251X, A272P, T286A, E291D, V292I, I293V, Q334P, G335DG
 NJIH0270NJIH0270MF622821NRTINNRTIM41L, M184V, T215YA98G, K103NK20R, V35T, V60I, D121H, K122E, K173T, Q174K, D177E, I178L, T200A, Q207D, V245Q, E248D, D250EG
 NJIH0264NJIH0264MF622815NRTINNRTIM41ML, M184V, L210W, T215Y, K219QA98G, K103N, M230LV35T, E36D, V60I, S68SG, D121H, K122E, K173R, Q174D, D177E, I178M, T200A, Q207K, R211K, D218E, L228R, V245Q, E248D, D250G, S251NG
 NJIH0226NJIH0226MF622777NRTINNRTIM41ML, D67DN, K70KR, M184V, T215Y, K219KEA98G, V108VIK20R, E28EK, V35T, T39TA, K49KR, V60I, K101KQ, D121H, K122E, I135T, E138EQ, K166KR, K173T, Q174R, D177E, Y181X, T200A, E203EK, Q207E, R211K, V245Q, E248N, D250E, S251VG
 NJIH0225NJIH0225MF622776NRTINNRTIM184VA98G, Y181VK20R, V35T, V60I, D121H, K122E, I135T, K166R, K173T, Q174R, D177E, T200A, E203K, Q207E, R211K, V245Q, E248N, D250E, S251V, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I329V, Q334L, G335DG
 NJIH0216NJIH0216MF622767NRTINNRTIM41L, M184V, L210LW, T215FA98G, K103NV35T, T39TA, V60I, V118VI, K122E, D123S, I132V, I135T, S162C, K173A, Q174K, D177E, I178M, Q197E, T200A, Q207D, R211K, L228R, V245Q, E248D, D250EG
 NJIH0204NJIH0204MF622755NRTINNRTIM41ML, M184V, T215YA98G, K101E, G190SV35T, V60I, T69TN, V118I, K122E, D123S, I135K, K173I, Q174K, D177E, T200A, I202V, E203EA, Q207E, R211T, F214L, V245Q, E248D, D250EG
 NJIH0184NJIH0184MF622735NRTINNRTIM41ML, D67N, K70R, M184V, K219QA98G, G190AV35T, K49R, V60I, K122E, D123T, Q174N, D177E, T200A, Q207E, R211K, T215X, D218E, P243X, V245Q, E248D, D250EG
 NJIH0183NJIH0183MF622734NRTINNRTIK70KR, M184VA98G, G190AP25PA, V35T, K49R, V60I, K122E, D123X, T128TI, Q174N, D177E, T200A, Q207E, R211K, P243S, V245Q, E248D, D250EG
 NJIH0176NJIH0176MF622727NRTINNRTIK70Q, M184VA98G, K103N, V108IK20R, V35T, T39L, V60I, K102R, L109I, K122E, I135T, I142V, K173T, T200A, Q207D, F214L, D218E, H221YG
 NJIH0175NJIH0175MF622726NRTINNRTIM184VA98G, K103N, V108IV35T, T39L, V60I, K122E, I135T, I142V, K173T, T200A, Q207D, F214L, D218E, H221Y, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, K311R, D324E, I329V, Q334L, G335DG
 NJIH0164NJIH0164MF622715NRTINNRTID67N, T69D, K70R, L74I, M184V, T215F, K219QA98G, K103N, V108IV35T, E36D, I94L, D121H, K122E, I135L, I167IV, K173A, Q174K, D177E, I178X, T200A, Q207E, R211K, D218E, V245Q, E248NG
 NJIH0163NJIH0163MF622714NRTINNRTID67N, T69D, K70R, L74I, M184V, T215F, K219QA98G, K103N, V108IT7TA, V35T, E36D, I94L, D121H, K122E, I135L, K173X, Q174K, D177E, I178X, T200A, Q207E, H208HY, R211K, D218E, V245Q, E248XG
 NJIH0136NJIH0136MF622687NRTINNRTIA62V, K65R, M184VA98G, V179E, Y181CK20R, V35T, K122E, D123N, I142IT, K173X, Q174X, I195L, T200A, I202IV, Q207D, V245Q, E248D, D250E, S251NG
 NJIH0135NJIH0135MF622686NRTINNRTIA62AV, K65KR, D67DG, K70KE, M184VA98G, V179E, Y181CK20R, V35T, V60I, K122E, D123N, I142X, K173A, Q174R, I195L, T200A, I202IV, Q207D, H221HY, V245Q, E248D, D250E, S251N, K275Q, T286A, E291D, V292I, I293V, D324EG
 NJIH0104NJIH0104MF622655NRTINNRTIK70E, M184VA98G, Y181C, G190AK20R, V35T, T39E, V60I, K66X, K101X, K122E, I135T, T165TI, K173I, Q174K, D177E, T200A, Q207E, R211K, F214L, L228R, V245Q, D250EG
 NJIH0103NJIH0103MF622654NRTINNRTIK70E, M184VA98G, Y181C, G190AK20R, V35T, T39E, V60I, K101X, K122E, I135T, T165TI, K173I, Q174K, D177E, T200A, Q207E, R211K, F214L, L228R, K238KE, V245X, D250EG
 NJIH0078NJIH0078MF622629NRTINNRTIM184V, K219EA98G, Y181CV35T, T39K, E40D, K122E, D123E, S162X, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, E248D, D250E, S251DG
 NJIH0077NJIH0077MF622628NRTINNRTIM184V, K219EA98G, Y181CV35T, T39K, E40D, K122E, D123E, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, E248D, D250E, S251D, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, Q334P, G335DG
 NJIH0054NJIH0054MF622605NRTINNRTIK70E, M184VA98G, K101KE, Y181CE6EK, V35T, V60I, K122E, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, L228R, V245Q, E248D, D250EG
 NJIH0053NJIH0053MF622604NRTINNRTIK70KQ, M184VA98G, Y181CE6EK, V35T, E40ED, V60I, V118G, P119T, K122E, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, P225X, V245Q, E248X, D250E, A272P, K281KR, T286A, E291D, V292I, I293V, E312D, I329V, Q334S, G335DG
 NJIH0032NJIH0032MF622583NRTINNRTID67N, K70R, M184V, K219EA98G, Y181CK20R, V35T, T39K, E40D, V60I, V106I, D123E, K173A, Q174K, D177K, T200A, I202V, Q207N, R211K, F214L, V245K, E248D, D250E, S251AG
 NJIH0015NJIH0015MF622566NRTINNRTIK70E, M184VA98G, Y181CV35T, K122E, D123S, I135M, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, L228R, V245Q, E248D, D250EG
 NJIH0008NJIH0008MF622559NRTINNRTIK70E, M184VA98G, V179E, Y181CK20R, V21I, V35T, T39A, E40D, V60I, K122E, D123S, K173I, Q174K, D177E, T200A, Q207E, L228R, V245Q, E248D, D250E, S251DG
 NJIH0006NJIH0006MF622557NRTINNRTID67G, K70E, Y115F, M184VA98G, Y181C, G190AK20R, V35T, T39K, K43Q, V60I, V90I, K122E, K173A, Q174K, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250EG
 NJIH0005NJIH0005MF622556NRTINNRTID67N, K70E, M184VA98G, K101KE, Y181C, G190AK20R, V35T, T39K, K43Q, V60I, V90I, K122E, K173A, Q174K, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329V, G335DG
 NJIH0004NJIH0004MF622555NRTINNRTIK70E, Y115F, M184VA98G, Y181CK20R, V35T, T39E, V60I, K64KR, S105T, V106I, D123E, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L, H221Y, L228R, V245K, E248D, D250E, S251TG
 NJIH0003NJIH0003MF622554NRTINNRTIM184V, K219EA98G, Y181CK20R, V35T, T39E, K49R, V60I, K103KR, D123E, K173T, Q174R, D177E, I178L, L187F, T200A, E203K, Q207E, R211K, F214L, D218E, V245K, E248D, D250E, S251T, A272P, I274IV, Q278H, T286A, E291D, V292I, I293V, P294T, E297T, L301M, I329V, Q334P, G335DG