<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation V90I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 27
Isolates 27
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patDEL02_DEL707AJ577880AZT, DDI, 3TC, D4T, ABC, UnknownNVP, UnknownM41L, D67N, K70R, M184V, T215Y, K219EK103NV35T, T39L, V60I, W88C, V90I, K101Q, V118I, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, E203D, Q207D, R211K, F214LG
Non-B Workgroup (2005)PL3510257431AY901538AZT, DDI, D4T, 3TCNVP, EFVA62AV, K65R, K70R, V75I, F77L, F116Y, Q151MY181C, G190A, F227LV21I, V35T, E40D, K43KR, T58N, S68G, V90I, A98S, T139TA, R172K, K173T, Q174K, D177E, I195K, G196E, T200A, R211S, F214L, H221Y, E224D, V245Q, E248D, D250E, A272P, T286A, A288AT, E291D, V292I, I293V, E297AG
 PL2643484787 AZT, 3TCEFVT215YK103N, V179EV35T, V90I, A98S, K122E, D123S, I135K, S162C, K173I, Q174K, D177K, T200E, I202V, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, V317AT, D324E, I329VG
 PL45291105157 AZT, 3TC, D4T, TDFEFVD67N, K70R, K219QK103N, P225HV35I, V60I, V90I, A98S, K122E, D123S, I135L, I142V, K173I, Q174K, D177E, I178L, T200A, Q207K, R211S, V245Q, D250E, S251D, A272P, K275KQ, T286A, E291ED, V292I, I293V, E297A, D320E, D324E, I329VG
 PL4673984133 AZT, 3TC, TDF, DDIEFVK65KR, M184MVL100LI, K103KN, V108VIM, P225PHV35T, K43R, V60I, K64R, V90I, A98S, K122E, D123S, S162A, K173KR, Q174E, D177E, I195K, T200A, V245Q, E248A, D250E, A272P, V276IT, K277KR, T286A, E291D, V292I, I293V, E297AT, D320E, D324E, I329V, Q334PG
 PL5133996552 AZT, 3TC, TDFEFVV75M, M184VY188LK13KNT, K32KN, L34LF, V35T, K43R, V60I, V90I, K122E, D123N, I135T, S162H, F171Y, K173T, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, V292I, E297A, V317A, D324EG
Baxter (2006)48-12731273-30904DQ877793NRTINNRTIM41L, D67N, K70R, L74I, M184V, T215F, K219QK103N, F227LV35T, E42EK, K49KR, V60I, T69N, V90I, K122E, D123S, A158S, E169D, K173R, Q174K, D177E, I178M, G196E, T200A, E203A, Q207E, H208Y, R211K, D218E, L228LH, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, D324E, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394RG
Gody (2008)Pt032Pt032 D4T, 3TCNVPM41L, M184V, T215F V90I, K122E, D123S, I135T, S162A, F171Y, K173A, Q174K, D177E, I178M, T200A, Q207EG
Hawkins (2009)P634ZZP634FJ931140D4T, 3TCNVPM41L, M184V, T215FG190AV35T, K49R, V60I, V90I, D121H, K122E, I135T, E138Q, T139TI, S162D, K166KR, K173T, Q174K, D177E, T200A, I202V, Q207E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, I329VG
 P638ZZP638FJ931143D4T, 3TCNVPM184VK101KHNQ, V106A, F227FLE6Q, K20R, V35T, E40D, K49R, I50V, V60I, V90I, K122E, D123S, S162A, K166Q, K173T, Q174K, D177E, I178L, T200A, Q207D, R211K, F214L, V245Q, E248N, D250E, S251N, A272P, T286A, E291D, V292I, I293VG
 Q776ZZQ776FJ931241D4T, 3TCNVPM184VY181CK32I, V35T, K49R, V60I, V90I, K102R, K122E, D123N, I135K, S162H, K173T, Q174K, D177E, I178L, T200A, Q207E, V245Q, E248D, D250E, A272P, V292I, I293V, I329VG
 R153ZZR153FJ931348D4T, 3TCNVPK70KR, M184V, T215TFISA98G, V108VI, Y181CP4S, K20R, V35T, V60I, R83RK, V90I, K122E, I135V, T139TR, S162A, K173T, Q174K, T200A, Q207E, R211K, F214FL, V245Q, A272P, T286A, E291D, I293V, E297A, L301MG
 R461ZZR461FJ931387D4T, 3TCNVPM184VK101H, Y181CV35T, T39M, V60I, V90I, D121H, K122E, D123S, I135R, T139K, S162H, E169D, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214FL, V245Q, E248N, D250E, A272P, E291D, V292I, I293V, D324EG
 R257ZZR257FJ931402AZT, 3TCNVPM41L, M184V, L210LW, T215FA98G, K103NV8VI, V35T, V60I, V90I, K122E, D123S, I135T, E138Q, S162Y, Q174N, D177E, I178L, G196GE, T200A, Q207D, V245Q, E248D, D250E, A272P, V276VI, T286A, E291D, V292I, I293V, D324EG
 R369ZZR369FJ931407AZT, D4T, 3TCNVPM184VK101EE28EGKR, V35T, K49R, V60I, V90I, K122E, D123S, I135V, T165I, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214L, V245Q, E248N, D250E, A272P, T286A, E291D, I293V, P294T, I326VG
 R359ZZR359FJ931416NRTINVPM184VK103NE6D, K11KR, V35T, E40D, V90I, A98S, K122KE, D123E, I135T, T139TR, S162A, K173KR, Q174N, D177E, I178M, T200A, Q207E, H221HY, V245T, D250DN, T286A, E291D, V292I, I293V, K311RG
 R272ZZR272FJ931448TDF, 3TCNVPM184IY181CV35T, T39N, V60I, V90I, K101KR, T165L, E169D, K173A, Q174R, D177E, T200E, Q207A, V245Q, E248N, A272P, K277R, T286A, I293V, P294T, E297Q, I329VG
Burda (2010)06ARC00706ARC007GQ344985D4T, 3TC, AZTNVP, EFVA62V, K65R, V75I, F116Y, Q151M, M184IV108I, Y181CI31L, V35I, S68G, T69I, V90I, K104R, K122E, S162A, K173T, Q174K, D177E, I178MG
Knops (2010)Pat05Pat05GU991866DDIEFVD67N, K70R, L74I, T215F, K219QK101P, K103NI2IV, V60I, T69N, V90I, I94IL, K102Q, V106VI, K122E, D123S, I135T, S162Y, K173S, Q174K, D177E, I178IL, I195L, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, A288AT, V292VI, I293V, E297A, V317A, D324E, I329IVG
Charpentier (2011)CR-56CR-56FJ688262AZT, 3TCNNRTIM184VG190GEQRE6S, V35T, T39TA, V90I, K102G, K122E, D123S, I135T, S162Y, K166KR, K173T, Q174K, D177E, I178M, T200EK, Q207E, V245Q, D250E, A272P, K275R, V276I, L283I, E291D, V292I, I293V, E297A, E312EK, D324E, I329VG
Afonso (2012)ANG74ANG74JN937086NRTINNRTI  V35T, T39N, E40D, K49R, V60I, V90I, V106I, K122E, D123G, E138A, S162D, K173A, Q174K, V179I, Q207D, R211K, V245QG
Pircher (2013)B1111B1111JX110212D4T, 3TC, AZTNVPM184VK103NP4S, V35T, V60I, S68G, V90I, K122E, D123S, T128TP, T131TP, T139R, S162C, K173A, D177E, I178M, T200A, Q207K, R211K, V245Q, E248D, D250E, S251A, W252GG
 B1103B1103JX110205D4T, 3TC, AZTNVPM184V, T215FK101N, Y181CE6N, T7TP, P9S, E28K, V35T, T39K, E40D, V90I, K122E, D123S, S162Y, K166R, K173T, D177E, T200A, Q207E, R211K, V241L, V245Q, E248D, D250EG
Rawizza (2013)LN9690LN9690KF241491NRTINNRTID67G, K70R, M184V, K219EK103N, Y181CK20R, V35T, V60I, S68G, V90I, A98S, K122E, D123S, I135T, Q174KR, D177E, T200A, Q207E, R211K, L228R, V245E, E248D, D250E, S251D, A272P, K275R, K277T, T286A, E291D, V292I, I293V, E297A, Q334HG
 LM4439LM4439KF241483NRTINNRTIK65R, T69~, K219RK103NS, Y181C, G190AK20R, V35T, K46M, V60I, I63L, S68G, V90I, D121H, K122E, K173T, Q174K, D177E, E194EK, G196GR, T200E, I202V, Q207E, H221Y, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, D324EG
 LN4711LN4711KF241488NRTINNRTI  V35T, V90I, K104R, K122E, D123N, K173A, Q174K, D177E, I178M, T200A, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, L295M, D324E, I329VG
 LN0609LN0609KF241484NRTINNRTIA62V, V75I, F77L, F116Y, Q151MY181C, G190AP4T, K20KR, K22R, I31L, V35T, T39K, E40D, T58N, S68G, V90I, V118I, K122E, T165I, K173A, Q174R, D177E, T200A, L205F, Q207E, R211K, F214L, V245Q, E248D, D250E, S251H, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329VG