<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 22
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL3916866371AY901632AZT, DDC, 3TC, D4TEFVD67G, K70R, M184V, T215F, K219EK103N, M230LV35T, K43R, V60I, S68G, A98S, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I195M, T200A, Q207K, R211S, L228LH, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334LG
 PL53397101698 NRTIEFVK65R, Q151M, M184IK101E, Y181C, M230LV35T, S68G, V90VI, A98S, K122E, D123S, I135R, I167IV, K173R, Q174K, D177E, I195IL, T200A, I202V, R211S, D237A, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, D324E, L325I, I326V, I329VG
 PL54779105582 TDF, 3TCNVPK65R, M184IY181C, M230LV35T, A98S, K173I, Q174E, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, E297A, D320E, D324E, I329VG
Hawkins (2009)Q981ZZQ981FJ931286D4T, 3TCNVPK65R, V75VA, K219EY181C, M230LK20R, V35T, V60I, S68G, K101*Q, K104R, K122E, D123N, P140T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, F214L, H221Y, L228R, V245Q, E248D, D250E, S251R, A272P, T286A, E291D, V292I, I293V, K311R, I329VG
 Q595ZZQ595FJ931320D4T, 3TCEFV, NVPM184VK103N, P225PH, M230LV35T, V60I, T69TN, K122E, K173T, Q174R, D177E, T200A, Q207G, R211K, H221HY, V245Q, E248S, D250E, A272P, K275R, T286A, E291D, V292I, I293V, P294T, S322T, I326VG
 R127ZZR127FJ931334TDF, 3TCEFV, NVPK65R, M184V, K219KEA98G, V108I, V179E, Y181C, M230LP4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329VG
El-Khatib (2010)Pat06810ZA_SAVE2429HQ012346D4T, 3TCNVPL74V, M184VK103N, M230L, L234IV21VI, V35T, V60I, V90VI, K122E, I142V, S163T, K173L, Q174K, D177E, I178M, T200A, Q207N, R211K, H221Y, V245Q, E248D, D250E, S251TG
Sigaloff (2011)HIV105126HIV105126JN132365AZT, 3TCNVPM41L, D67DG, T69D, K70R, M184V, T215F, K219QA98G, V179E, Y181C, M230LV35T, T39A, V60I, K102Q, K122E, D123G, K173T, Q174K, D177E, I178M, T200A, Q207N, D218E, L228H, Q242H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293VG
Etiebet (2013)10127607NG.SN235HQ843638TDF, FTCEFVK65R, M184IL100I, K103N, M230LP14S, V35T, S68G, T69N, W88C, K122P, K173I, Q174K, D177E, I178L, T200A, E203Q, R211KG
Theys (2013)32693269KC219244TDF, 3TCNVPK65R, M184IY181C, M230LA98S, K173I, Q174E, D177E, T200A, Q207K, R211SG
 55935593KC219416TDF, FTCNVPK65R, M184VK101E, Y181C, G190A, M230LV60I, A98S, V106I, K122E, D123T, I135L, E138A, K166R, K173S, Q174R, D177E, I195K, G196E, T200A, R211SG
Theys (2013)113842113842 AZT, 3TCEFVM184VK103N, M230LV35T, V60I, A98S, K122E, D123S, Q174E, D177E, T200A, Q207K, R211S, H221Y, V245Q, E248D, D250E, A272P, K281R, T286A, E291D, V292I, I293V, D324E, I329VG
 147293147293 AZT, 3TCEFVM184V, T215FV179E, P225PH, M230L, K238TV35T, V60I, A98S, K122E, D123N, I135T, S162C, K173I, Q174K, T200A, I202V, Q207K, R211S, H221HY, V245Q, E248D, D250DE, A272P, T286A, E291D, V292I, I293V, E297T, D324E, I329V, Q334PG
 BM20042BM20042 AZT, 3TCEFVM184V, K219NV179E, M230LV35T, K43KR, K49R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292VI, I293V, E297A, D320E, D324E, I329VG
 108872108872 AZT, 3TCEFVM41L, M184V, T215YK103N, M230L, L234IV35T, V60I, A98S, K122E, D123S, I135V, K173R, Q174K, D177E, I178M, T200A, R211S, H221Y, L228R, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, D320E, D324E, I326V, I329VG
Steegen (2016)GFWCB054GFWCB054KU128340TDF, 3TC, FTCEFVL74V, Y115F, M184V, K219KEK103N, Y188C, M230LV35T, T39A, V60I, S105T, V106I, D121H, K122E, E138A, K173T, Q174K, D177E, I178L, V179VI, T200A, Q207S, R211K, L228H, V245Q, E248D, D250EG
Chaplin (2017)NJIH0264NJIH0264MF622815NRTINNRTIM41ML, M184V, L210W, T215Y, K219QA98G, K103N, M230LV35T, E36D, V60I, S68SG, D121H, K122E, K173R, Q174D, D177E, I178M, T200A, Q207K, R211K, D218E, L228R, V245Q, E248D, D250G, S251NG
 NJIH0128NJIH0128MF622679NRTINNRTIK65R, M184IV179E, Y181C, M230LV35T, T39M, V60I, V90VI, D123DN, I135T, T165TI, K173T, Q174R, T200A, Q207K, R211K, V245Q, E248D, D250E, S251NG
 NJIH0127NJIH0127MF622678NRTINNRTIK65R, M184IV179E, Y181C, M230LV35T, T39M, V60I, D123DN, I135T, K173T, Q174R, T200A, Q207K, R211K, V245Q, E248D, D250E, S251NG
 NJIH0062NJIH0062MF622613NRTINNRTIK65R, L74LV, M184IL100I, K103N, M230LV35T, K49R, E53D, T58TS, V60VI, K64KR, S68X, K122E, D123S, S162A, E169D, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, K219X, L228LPG
 NJIH0034NJIH0034MF622585NRTINNRTIK65R, M184VK103N, V106M, M230LV35T, K64KR, K122E, S163N, K173A, Q174N, D177E, T200A, Q207D, V245Q, E248D, D250EG
Rhee (2017)95219521KY358929TDF, 3TCEFVK65R, F77FL, M184IK103N, V108VI, Y181C, M230LK20R, V35I, V60I, V90I, K122E, D123G, I135L, S163ST, K173T, Q174K, T200A, Q207A, V245Q, E248D, D250E, S251NG