<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation P225H
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 3
Patients 32
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL1495255878AY901522AZT, 3TCEFVM184V, K219HQK103N, P225HE6A, K20KR, K22KN, V35T, E36A, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, F214L, D218DE, V245Q, D250E, A272P, T286A, E291AD, V292I, I293V, E297A, D320E, D324EG
 PL3579358927AY901552AZT, 3TCEFVM184VP225H, K238TE28K, V35T, T39E, K43R, V60I, A98S, K101KQ, K104KT, D121H, K122E, I135T, I142V, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324EG
 PL2265063406AY9016043TC, DDIEFVL74V, M184VK103N, P225H, Y318FV35T, V60I, A98S, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293IV, E297A, L310LRG
 PL1584967492AY901642D4T, 3TC, AZTEFVM41ML, M184VK103N, P225HV21I, V35T, K43R, V60I, A98S, K102R, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL53378101651 AZT, 3TCEFVD67N, K70R, M184V, K219QK103N, P225HV35T, T39TIM, K43R, V60I, A98S, K122E, D123S, I135T, K173R, Q174K, N175Y, T200E, Q207A, R211NS, D218E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, K311R, D324E, I329VG
 PL3531396857 D4T, DDI, ABC, AZT, 3TCNVP, EFVD67GK103N, P225H, K238TV35T, V60I, A98S, K122E, D123S, I135T, S162A, K173I, Q174K, D177E, T200A, Q207G, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297AT, A304E, D324E, L325I, I329V, Q334LG
 PL37927102127 3TC, D4TEFVV75I, M184V, T215YK103N, P225HV35T, V60I, A98S, K122E, D123S, I132L, I135T, K173T, Q174K, D177E, I178M, T200A, Q207K, R211S, L228I, V245Q, D250E, A272P, T286A, V292I, I293V, E297A, D320E, D324E, I329VG
 PL3866999587 D4T, DDI, AZT, 3TCEFVM184VK103N, P225H, K238KTV21I, V35T, K43KR, A98S, K122E, D123S, I135T, Q174N, D177E, I195K, T200A, R211NS, V245Q, E248V, D250E, I257L, A272P, T286A, A288AS, E291D, V292I, I293V, E297A, A304E, D320E, D324E, I329VG
 PL4268876257 AZT, 3TC, DDIEFVM184VK103N, P225HV35T, K43R, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
 PL45291105157 AZT, 3TC, D4T, TDFEFVD67N, K70R, K219QK103N, P225HV35I, V60I, V90I, A98S, K122E, D123S, I135L, I142V, K173I, Q174K, D177E, I178L, T200A, Q207K, R211S, V245Q, D250E, S251D, A272P, K275KQ, T286A, E291ED, V292I, I293V, E297A, D320E, D324E, I329VG
 PL5053294425 AZT, 3TCEFVM184VK103N, P225HK20R, V35T, V60VI, A98S, K122E, D123S, K126KR, I135T, K173IM, Q174K, D177E, I178V, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
Pircher (2013)B1126B1126JX110226D4T, 3TC, AZTNVPM41L, D67N, K70R, M184V, T215YK103N, V106A, P225H, F227LP4PS, K20R, V35T, T39N, E40D, P119PS, K122E, V148G, K173A, Q174K, D177E, I178L, S191SF, T200A, Q207N, R211KG
Theys (2013)78447844KC219560TDF, FTCEFVM184VA98AG, K103N, V179E, P225HK122E, D123S, I135T, I142IT, S162A, K173T, Q174K, D177E, T200A, Q207K, R211S, F214FLG
 1062010620KC219765TDF, FTCEFVK70KT, L74I, Y115YF, M184VK101E, V179EQ, G190S, P225HK49R, V60I, V90I, A98S, D121HY, K122E, E138G, I142IT, S162SN, Q174A, D177E, I178IM, I195K, T200AG
 56045604KC219417TDF, FTCEFVM184VK103N, V108VI, P225HV60I, A98S, K122E, I135T, L149P, P150R, K154T, I159IT, Q161E, S162T, K173M, Q174K, D177E, T200A, Q207A, R211SG
 1006410064KC219720TDF, FTCEFVM184VK103N, P225HV60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211NG
 62006200KC219478TDF, FTCEFVM184VK103N, P225HV60VI, A98S, K122E, D123S, I135T, K173T, Q174K, T200A, Q207K, R211SG
 65706570KC219498NRTI, TDFNNRTID67N, K70R, M184V, T215I, K219EK103N, P225HV60I, A98S, K122E, D123S, I135T, S162AT, Q174N, D177E, T200A, Q207KR, R211SG
 57665766KC219440NRTI, TDFNNRTIM41L, D67N, V75M, M184V, L210W, T215Y, K219RV106A, G190A, P225H, F227LE44D, V60I, R72E, A98S, V118I, D121H, K122E, S162D, K173A, Q174K, D177E, I178L, G196E, E203K, Q207D, H208Y, R211K, H221YG
 81768176KC219575NRTI, TDFNNRTIK70E, M184VK103N, P225HV60I, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, I178M, T200A, Q207K, R211SG
 99369936KC219713NRTI, TDFNNRTID67G, K70R, M184V, T215I, K219EK101E, V179E, P225HE40D, K43R, V60I, S68G, A98S, K122P, D123S, I135R, S162A, K173R, Q174K, D177E, I195K, G196E, Q197P, T200A, R211SG
 86238623KC219606NRTI, TDFNNRTI K103N, P225HE40D, V60VI, A98S, D121H, K122E, K173T, Q174K, D177E, T200A, Q207K, R211S, F214LG
 27252725KC219195NRTI, TDFNNRTID67G, K70E, T215Y, K219RK103N, P225HV60I, A98S, K101KQ, K122E, D123S, I135KT, S163T, Q174E, D177E, V179I, I195K, T200AG
 93339333KC219688NRTI, TDFNNRTIM184V, T215YP225HA98S, K122E, D123GS, I135V, S162T, K173R, Q174K, D177E, G196GR, Q207EG
 70477047KC219531NRTI, TDFNNRTIM184VK103N, P225HV60I, K64R, V90VI, D121DE, K122E, D123E, I135V, S162AT, K173A, Q174K, D177E, I178M, T200A, Q207G, R211KG
 24062406KC219170NRTI, TDFNNRTID67N, K70R, K219QK103N, P225HV60I, V90I, A98S, K122E, D123S, I135L, I142V, K173I, Q174K, D177E, I178L, T200A, Q207K, R211SG
 57515751KC219436NRTI, TDFNNRTIM184VK103N, P225HK43R, K49KR, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211SG
 24912491KC219177NRTI, TDFNNRTIM184VK103N, P225HA98S, K122E, D123S, I135T, K173R, Q174K, D177E, I178V, T200A, I202V, Q207E, R211SG
 59415941KC219460NRTI, TDFNNRTID67N, K70RK103N, P225HK43R, V60I, A98S, K122E, D123S, I135T, Y146S, K173T, Q174K, D177E, T200A, Q207G, R211S, F214LG
 93129312KC219680NRTI, TDFNNRTIM41L, K70N, L74V, M184V, K219KRK103N, P225H, F227FLV60I, A98S, K104KN, K122E, D123S, I135T, K173M, Q174K, D177E, I178L, T200A, Q207K, R211SG
 93539353KC219696NRTI, TDFNNRTIM184VP225HV60I, W88C, A98S, K122E, K173I, Q174K, D177E, I178L, T200A, Q207K, R211S, F214LG
 75117511KC219546NRTI, TDFNNRTID67N, K70R, M184V, T215V, K219QK103N, P225HK43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211SG