<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation G190S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 6
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL2798468322AY901659D4T, DDIEFVM41L, T215YG190SE28A, V35T, K43KR, A98S, K101Q, L109I, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
Baxter (2006)48-22382238-30731DQ877877NRTINNRTIK219QG190SV35T, K43R, V60I, A98S, K101Q, K122E, D123S, S162N, K173T, Q174K, D177E, T200A, Q207K, R211S, H221Y, V245Q, E248D, D250E, A272P, T286A, E291A, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, K390R, Q394R, A400VG
Hawkins (2009)Q822ZZQ822FJ931255D4T, 3TCNVPM41L, K65R, T69~, K219RY181C, G190SL34IV, V35T, T39A, V60I, S68G, W88S, V106VI, V118I, K122E, P157A, T165TI, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, V245Q, E248D, D250K, I270IV, A272P, T286A, E291D, V292I, I293V, L301W, I329VG
 R107ZZR107FJ931358TDF, 3TCNVPA62AV, K65R, M184VK101E, Y181C, G190SV35T, S68SG, D123E, S162A, K173A, Q174K, D177E, T200A, Q207E, R211RK, V245Q, D250E, A272AP, E291D, V292I, I293V, E297K, I329VG
 R441ZZR441FJ931453AZT, D4T, 3TCNVPD67DG, L74LV, M184IY181C, G190SV35T, V60I, T69S, K101Q, K122E, D123S, I135V, I142IV, S163ST, T165I, K173T, Q174K, D177E, T200A, I202IV, Q207N, V245Q, E248N, D250E, A272P, E291D, V292I, I293V, I329VG
Pircher (2013)B1112B1112JX110213D4T, 3TC, AZTNVPK70E, M184VA98G, V179E, G190SK20R, K22R, V35T, E36K, T39D, E40D, V60I, W88C, K102Q, K122P, E138A, T139V, K173T, Q174K, D177E, T200A, E203K, Q207E, F214L, V245QG
Theys (2013)1062010620KC219765TDF, FTCEFVK70KT, L74I, Y115YF, M184VK101E, V179EQ, G190S, P225HK49R, V60I, V90I, A98S, D121HY, K122E, E138G, I142IT, S162SN, Q174A, D177E, I178IM, I195K, T200AG
 80648064KC219568TDF, FTCEFVD67DG, K70KQ, L74LI, V75VL, M184VK101E, Y181YC, G190SV60I, A98S, V106I, D123N, I135V, E138EA, K166R, K173I, Q174K, D177E, T200A, Q207E, R211RSG
 59015901KC219453NRTI, TDFNNRTIA62V, V75I, M184V, K219NK101E, Y181C, G190SK43KR, A98S, K122E, D123S, K173V, Q174K, D177E, T200A, Q207G, R211KG
 90539053KC219647NRTI, TDFNNRTIM41L, L210W, T215YK101H, G190SK43KR, A98S, L109I, K122E, D123N, I135T, K173IT, Q174K, D177E, T200A, Q207K, R211NG
 89378937KC219626NRTI, TDFNNRTIM41L, L74V, T215CK101E, Y181C, G190SV60I, A98AS, D121H, K122E, D123S, I135V, K173T, Q174K, D177E, T200A, Q207K, R211SG
Chaplin (2017)NJIH0204NJIH0204MF622755NRTINNRTIM41ML, M184V, T215YA98G, K101E, G190SV35T, V60I, T69TN, V118I, K122E, D123S, I135K, K173I, Q174K, D177E, T200A, I202V, E203EA, Q207E, R211T, F214L, V245Q, E248D, D250EG
 NJIH0066NJIH0066MF622617NRTINNRTIA62AV, F77FL, Y115YF, F116Y, M184VG190SV8VI, V21VI, V35T, V60VI, T69TN, V75X, K101A, K104R, K122E, D123S, Q151X, K173T, Q174K, D177E, I178M, T200A, Q207EG
 NJIH0065NJIH0065MF622616NRTINNRTIA62V, V75I, F77L, F116Y, Q151M, M184VG190SV8VI, V21I, V35T, T69N, K101A, K104R, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, D324E, Q334R, G335DG