<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation G190A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 52
Isolates 53
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL40555413AY901517DDC, AZT, 3TC, DDI, D4TNVP, EFVM41L, D67N, K70R, V75T, T215Y, K219EK103N, Y181C, G190AV35T, K43R, V60I, T69N, A98S, K101Q, K122E, D123N, I135T, R172RK, K173I, Q174K, D177E, I178IM, T200A, E203K, Q207E, R211NS, D218DE, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324EG
 PL3510257431AY901538AZT, DDI, D4T, 3TCNVP, EFVA62AV, K65R, K70R, V75I, F77L, F116Y, Q151MY181C, G190A, F227LV21I, V35T, E40D, K43KR, T58N, S68G, V90I, A98S, T139TA, R172K, K173T, Q174K, D177E, I195K, G196E, T200A, R211S, F214L, H221Y, E224D, V245Q, E248D, D250E, A272P, T286A, A288AT, E291D, V292I, I293V, E297AG
 PL509362410AY901586DDC, AZT, D4T, DDINVPM41L, D67N, L210W, T215YG190AV35T, K43R, E44ED, V60I, A98S, K122E, D123S, I135X, K173R, Q174E, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297AG
 PL1945463189AY901594Unknown, ABCUnknown, EFVM41L, D67N, K70KR, L74V, L210W, T215YK103N, Y181C, G190A, F227FLL34LI, V35T, T39L, V60I, A98S, K101KQ, K122E, D123NS, K173R, Q174N, D177E, T200A, Q207G, R211K, H221HY, K223KE, V245T, D250E, A272P, T286A, E291D, V292I, I293V, E297T, A304EG
  80060 Unknown, ABCUnknown, EFVM41L, D67N, L74V, M184V, L210W, T215YK101EQ, K103KN, Y181C, G190A, F227LL34I, V35T, T39L, V60I, A98S, V111VI, K122E, D123NS, K173R, Q174N, D177E, T200A, E203K, Q207ADE, H208HY, R211K, K223E, V245T, D250E, A272P, T286A, E291D, V292I, I293V, E297T, L303LRW, A304E, D324E, I329VG
 PL2053364517AY901618D4T, DDI, ABC, AZT, 3TCNVP G190AE6D, K20R, V35T, T39G, V60I, K104KR, D121H, K122KE, K173A, D177E, V179VI, G196K, T200A, Q207E, R211K, V245MT, D250E, A272P, E291D, V292I, I293V, E297A, E312D, P321S, D324EG
 PL888465233AY901627D4T, 3TC, DDI, ABCNVP, EFVM41L, L74V, T215Y, K219EK101AE, Y181C, G190A, P225PHV35T, T39TI, K43R, V60I, S68G, V90VI, A98S, K103KR, K122E, D123S, I135T, T165IM, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D320NG
 PL4356276535 AZT, 3TC, D4TNVPM41L, D67N, M184V, T215F, K219QK101KPQT, K103S, G190AT7TAP, E28EA, V35T, T39TA, V60I, A98S, D121H, K122E, I135T, K166R, Q174E, D177E, T200A, I202IV, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, I329V, K331NG
 PL4538780952 AZT, DDI, 3TC, D4TNVPM41L, D67N, M184V, T215F, K219QK101E, G190AE28K, V35T, E36D, T39A, K43R, V60I, D121H, K122E, D123S, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, I329V, K331NG
 PL4567581585 AZT, DDI, 3TC, D4TNVPM184V, T215FA98G, Y181C, G190AK20R, V21I, V35T, K49KR, V60I, K101Q, K122E, D123S, I135V, K166R, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, S251I, A272P, K277R, E291D, V292I, E297A, L301M, D324E, I329VG
 PL5039394037 AZT, 3TC, D4TNVPM184VK101H, G190AV35T, A98S, K122E, D123S, I135V, K166T, K173A, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248N, D250E, Y271F, A272P, T286A, E291D, V292I, I293V, E297A, A304E, I329VG
 PL5099295616 TDF, DDINVPK65RY181C, G190AV35T, T39M, K43KR, V60I, A98S, K122E, D123N, I135K, K173I, Q174K, D177E, I178L, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334LG
 PL5206098324 AZT, 3TCNVPM41L, M184VG190AV35T, V60I, A98S, K122E, D123S, I135V, S162C, Q174N, D177E, T200A, Q207K, R211S, H221Y, V245Q, E248D, D250E, A272P, T286A, E291D, I293V, E297A, L301M, D324E, I329VG
Weber (2005)M64940M64940AY714452AZT, 3TC, D4T, DDI, ABCNVPD67N, T69D, K70R, L74V, M184V, K219QA98G, Y181C, G190AE6S, K11T, K20R, V35T, V60I, K122E, D123S, K173T, D177E, G196R, T200A, I202IV, Q207E, R211K, F214L, L228H, V245Q, E248D, D250E, A272P, E291D, V292VI, I293V, E297AT, I309IM, D324E, Q332QEG
Baxter (2006)48-12511251-30602DQ877776NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215YA98G, K101E, G190AE28K, K32E, V35T, T39A, E44D, V60I, V118I, K122E, I135V, S162C, K173T, Q174K, N175Y, D177E, T200A, E203D, Q207K, R211EK, K223Q, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, S379A, I382M, Q394R, K395RG
 48-31863186-30506DQ878094NRTINNRTIM41L, D67N, L74V, M184V, T215Y, K219NA98G, K103N, G190AV35T, T39A, E44D, V60I, V118I, K122E, D123S, K173R, Q174K, D177E, V179T, T200A, R206M, Q207E, L210S, R211K, T216M, L228H, Q242H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335D, F346Y, M357R, R358G, G359S, A371V, A376S, I382V, Q394K, E399DG
 48-33183318-30924DQ878218NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215Y, K219NK101H, Y181C, G190AP4T, I5IV, E6K, V21I, E28K, K32I, V35T, V60I, V106T, V111I, V118VI, K122E, I135V, K173A, Q174K, D177E, I178L, G196GE, T200A, E203EK, Q207E, H208Y, R211K, W212C, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, S322A, D324E, I329V, Q334P, G335D, R356K, M357R, G359A, A371V, T377S, K390RG
Hawkins (2009)P607ZZP607FJ931124D4T, 3TCNVPL74LV, M184VK101E, G190AK20R, E28K, K32KE, V35T, T39N, W88C, L109LI, K122E, I142V, K173A, Q174K, D177E, I178L, Q197QK, T200A, K201KR, E204EK, Q207EV, R211K, F214L, V245Q, E248D, D250E, S251A, A272P, T286A, E291ED, V292I, I293V, E297A, L301M, P321S, D324E, E328D, I329VG
 P634ZZP634FJ931140D4T, 3TCNVPM41L, M184V, T215FG190AV35T, K49R, V60I, V90I, D121H, K122E, I135T, E138Q, T139TI, S162D, K166KR, K173T, Q174K, D177E, T200A, I202V, Q207E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, I329VG
 P636ZZP636FJ931142D4T, 3TCNVPM184VK101E, G190AK20R, E28K, V35T, V60I, K122E, D123E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, P243H, V245E, E248D, K275R, T286A, E291D, V292I, I293V, P294T, V317A, S322T, I326VG
 P648ZZP648FJ931152D4T, 3TCNVPD67N, K70R, M184V, K219QA98G, K101E, G190AK20R, E28K, K32E, V35T, T39N, V60I, K122E, K166R, K173T, Q174N, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 P676ZZP676FJ931166D4T, 3TCNVPM41L, D67N, T69D, M184V, L210W, T215YA98AG, Y181C, G190AS3C, T7TA, V35T, T39A, E44D, K122E, D123N, T139R, S162C, K173T, Q174K, D177E, I178M, T200A, E203K, Q207D, R211K, V245Q, E248D, D250G, A272P, T286A, E291D, V292I, I293V, T296S, V314I, I329VG
 P956ZZP956FJ931174D4T, 3TCNVPM184VG190AV35T, E36D, K101KT, K104R, D121DE, K122E, D123S, I135M, K173T, Q174K, T200A, Q207D, F214FL, V245Q, E248EDKN, D250E, S251SCNY, K281R, T286A, E291D, V292I, I293V, D324EG
 P623ZZP623FJ931184D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AE28EAKT, V35T, V60I, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K275KR, V276I, K277R, T286A, E291D, V292I, I293V, P294T, E297K, D324E, I329VG
 P945ZZP945FJ931189D4T, 3TCNVPM41L, V75M, M184V, T215YA98G, K101KE, G190AV35T, V60I, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, I329VG
 Q200ZZQ200FJ931205D4T, 3TCNVPD67N, K70R, M184V, T215TFIS, K219QK101E, G190A, Y318FE28K, K32KI, V35T, V60I, T69N, K104R, K122E, D123S, K173IR, Q174K, N175Y, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251N, T286A, E291D, V292I, I293V, E297AG
 Q214ZZQ214FJ931214D4T, 3TCNVPK70R, M184VK101H, Y181C, G190AK20R, V35T, T39K, E40D, K49R, V60I, T69N, K122E, I135V, T139V, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251SN, A272P, T286A, E291D, V292I, I293V, E297V, L301M, D324E, L325V, I329VG
 Q86ZZQ86FJ931221D4T, 3TCNVPM184VK101E, G190AK20R, V21VI, V35T, T39K, E40D, V60I, K104R, K122E, D123N, K173T, T200A, E203D, Q207N, R211K, F214L, V245Q, E248N, D250E, S251V, A272P, Q278H, K281R, E291D, V292I, I293V, E297T, L301M, A304E, I329VG
 Q789ZZQ789FJ931247D4T, 3TCNVPM184VK101E, G190AE28EK, K32R, V35T, V60I, K102R, K122E, D123G, K173T, Q174K, D177E, T200A, E203EK, Q207E, V245Q, E248N, D250E, A272P, L279M, T286A, E291D, V292I, I293V, D324E, I329VG
 Q795ZZQ795FJ931249D4T, 3TCNVPM184VG190AV35T, S48T, K104R, K122E, D123S, I142V, K166R, F171Y, Q174E, D177E, I178M, T200A, E204K, Q207N, V245Q, E248D, D250E, S251N, A272S, T286A, E291D, V292I, I293V, E312R, D324E, I326V, Q330HG
 Q446ZZQ446FJ931263D4T, 3TCNVPK70KR, M184VG190AE6A, K11Q, V35T, E36ED, T39L, K104R, D123S, D177E, T200A, Q207G, R211K, I244V, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I329VG
 Q977ZZQ977FJ931282AZT, D4T, 3TCNVPM184V, T215FK101E, G190AE28K, V35T, V60I, S68SG, V106VI, K122E, I135L, S162A, K173T, Q174K, N175NY, D177E, T200A, Q207E, R211K, V245K, A272P, T286A, E291D, V292I, I293V, I329VG
 Q975ZZQ975FJ931318D4T, 3TCNVPM184VK103S, G190AV35T, V60I, K122E, D123S, I135V, S162A, K166KR, K173I, Q174K, D177E, T200A, Q207AS, R211S, V245E, S251A, A272P, K277R, T286A, E291D, V292I, I293V, S322TG
 Q949ZZQ949FJ931323D4T, 3TCNVPM41L, M184V, T215FYA98G, K101E, G190AE28K, V35T, V60I, K173T, Q174K, D177E, I178M, T200A, Q207D, V245Q, S251N, A272S, T286A, E291D, V292I, I293V, K311R, E312K, D324E, I329VG
 Q411ZZQ411FJ931340D4T, 3TCNVPK65R, T69~, K219RK103N, Y181C, G190AK20R, V35T, V60I, D121H, K122E, K173T, Q174K, D177E, T200E, I202V, Q207E, H221Y, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, D324EG
 R26ZZR26FJ931343TDF, AZT, D4T, 3TCNVPK65R, K70KT, M184VK101E, Y181C, G190AV35T, V60I, S68SKNR, K102Q, V111VI, D121H, K122E, D123S, I135V, E138Q, S162A, K173A, Q174K, D177E, T200A, Q207QK, F214FL, V245Q, E248DN, D250DGNS, S251SN, A272P, T286A, E291D, V292I, I293V, P294TG
 R197ZZR197FJ931357TDF, 3TCNVPA62AV, K65R, Y115YF, M184VY181C, G190AK20KR, V21I, V60I, S68SN, K101R, K102KM, K122E, D123GS, I135T, S163T, T165TI, E169ED, F171FY, K173T, Q174KR, I178M, T200A, Q207E, R211K, H221HY, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, P294Q, D324E, I329VG
 R222ZZR222FJ931381NRTIEFV, NVPM184VK101E, K103N, G190AV35T, T39L, K122E, D123S, K173A, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, D324E, I329VG
 R250ZZR250FJ931395AZT, 3TCNVPM41L, D67DN, K70KR, M184V, T215FA98G, Y181C, G190AV35T, T39A, E44ED, K49R, V60I, V90VI, I94L, K104R, K122E, D123N, I132V, S162N, F171Y, K173T, Q174N, D177E, I178M, T200A, I202V, Q207E, R211K, F214L, H221Y, V245K, E248D, D250E, S251V, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R256ZZR256FJ931401AZT, 3TCNVPD67N, K70R, M184V, K219QA98G, G190AV35T, K49R, V60I, K122E, D123T, Q174N, D177E, T200A, Q207E, R211K, D218E, P243S, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, K311R, I329IVG
 R258ZZR258FJ931403AZT, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AK20R, V35T, I50IV, V60I, W88C, K104R, K122E, D123N, E138Q, I142V, K166R, K173T, Q174R, D177E, I178M, T200A, Q207E, R211S, F214L, V245Q, E248D, D250E, S251N, A272P, K277R, K281R, T286A, E291D, V292I, I293V, P321S, D324E, I329VG
 R367ZZR367FJ931405D4T, 3TCEFV, NVPM184V, T215YA98G, K101E, V108VI, Y181C, G190AK20R, E28K, K32KE, V35T, K49R, V60I, K104R, K122E, I135V, T139TI, K173IM, Q174K, D177E, T200A, Q207G, R211K, V241VI, V245Q, E248D, D250E, S251I, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I309IM, S322SA, I329VG
 R361ZZR361FJ931418TDF, 3TCNVPK65R, Y115F, M184VK101E, Y181C, G190AP4L, V35T, V60I, K104KR, V106I, D123S, K173V, Q174K, D177E, T200A, I202V, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I326VG
 R237ZZR237FJ931432TDF, AZT, D4T, 3TCEFV, NVPM184V, T215TNSYK101EQ, V108I, Y181C, G190AV21I, V35T, V60I, K122E, D123N, I135T, K173L, Q174R, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, S251N, A272P, G273N, K275R, K277R, T286A, E291D, V292I, I293VG
 R239ZZR239FJ931433AZT, 3TCNVPM41ML, D67N, K70R, M184V, T215F, K219EA98G, K101E, Y181C, G190AE28EK, V35T, V60I, T69N, K104R, K122E, D123N, K173T, Q174R, D177E, T200A, I202V, Q207E, F214L, L228H, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R265ZZR265FJ931441AZT, 3TCNVPM184VK101KE, V106VA, G190AK20R, V35T, T39N, E40D, K49KR, V60I, I135IT, E138A, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, D250E, S251D, A272P, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329VG
 R443ZZR443FJ931454NRTINVPM184VA98G, K101E, E138KQR, G190AV21VI, V35T, T39IM, E40D, V60I, W88WC, K104R, K122E, D123S, I132IV, I135T, K173T, Q174K, V179I, T200A, I202V, Q207D, R211K, F214L, V245Q, D250E, S251H, A272P, T286A, E291D, V292I, I293V, E297K, S322G, D324EG
Burda (2010)06ARC03606ARC036GQ344989D4T, 3TC, AZTNVP, EFVM184VK103N, V179E, Y181C, G190AV35T, K43N, K49R, I135V, S162D, E169A, K173A, Q174K, D177E, I178MG
 06LPH17HT06LPH17HTGQ344998D4T, 3TCNVP G190AE6K, V35T, E36D, T39A, K104R, K122E, I135V, I142V, S162A, T165I, K173T, Q174K, D177E, I178MG
Knops (2010)Pat08Pat08GU991869AZT, 3TC, D4T, DDIEFVM41L, D67N, K70R, L74LI, T215F, K219EQK101E, V108I, Y181C, G190A, Y318FK20R, V35I, T39A, K49KR, V60I, K102Q, V118VI, K122E, D123N, I135K, S162D, K173R, I178M, T200A, E204EQ, Q207DE, R211K, D218E, L228H, V245Q, E248ED, D250E, S251G, A272P, L283I, V292I, I293V, E297A, V317A, I329IVG
 Pat14Pat14GU9918753TC, DDINVP, EFVM41L, D67N, L74LV, L210W, T215Y, K219KEK101E, Y181C, G190AP1PA, V35T, T39TA, V60I, K102Q, K104KR, V118VI, K122E, D123S, I135T, E138T, K173N, Q174K, D177E, I178M, S191SCW, I195IM, T200A, E203EK, Q207D, R211K, D218DE, V245Q, E248D, D250E, A272P, L283I, V292I, I293IV, E297A, D324E, I329VG
 Pat19Pat19GU9918803TC, DDIEFVM41L, D67N, K70R, V75M, M184V, T215F, K219QY181C, G190AP4Q, K20R, V21I, V35I, T39A, V60I, K101KQ, K102Q, D121H, K122E, D123S, K166R, Q174R, D177E, I178M, V179Q, T200A, Q207E, H208Y, R211K, D218E, L228H, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, E297AT, R307RK, I329VG
Charpentier (2011)125CP 001 949 D4T, 3TCNVPM184VA98G, K101E, G190AV35T, T39N, E40D, V60I, K104R, K122E, D123N, I135V, I142V, K173T, D177E, T200A, Q207A, R211K, D237DE, V245Q, E248N, A272P, K281R, E291D, V292I, I293V, E297A, E312N, V317A, P321S, D324E, I329V, Q334EG

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