<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation V179E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 31
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL902961126AY901571ABC, D4TEFVT215TSK103N, V179EP4L, V35T, V60I, A98S, K122E, D123S, I135K, K173M, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, E312DG
 PL943966213AY901628D4T, 3TC, DDC, AZT, DDINVP, EFV V179EV35T, V60I, A98S, K122E, D123N, I135T, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K275KQ, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334LG
 PL846867575AY9016513TC, D4T, ABC, DDIEFVL74V, Y115YF, M184V, T215DK103N, V179EE28K, K32E, V35T, K43R, V60I, S68G, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297AV, D320E, D324E, I329VG
 TK2013TK2013a AZT, 3TC, D4T, ABC, DDIEFVM41L, L74V, M184V, L210W, T215YV179E, Y188LV21I, V35T, E36D, T39A, S48T, V60I, V106I, V118I, E169D, K173R, Q174K, D177E, T200E, Q207E, R211K, T240TM, V245Q, D250E, A272PS, E291D, V292I, I293V, E297KG
  TK2013b AZT, 3TC, D4T, ABC, DDIEFVM41L, L74V, M184V, L210W, T215YV179E, Y188LV21I, V35T, E36ED, T39A, S48T, V60I, V106I, V118I, E169D, K173R, Q174K, D177E, T200E, E203K, Q207E, R211K, T240TM, V245Q, D250E, A272PS, E291D, V292I, I293V, E297K, D324E, I329VG
 PL1014683346 NoneEFV V179E, Y188LV35T, V60I, A98S, K122E, D123S, I135T, T139I, E169EG, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297AVG
 PL2062582016 3TC, D4T, DDIEFV K103N, V179EV35I, A98S, K122E, D123S, E138G, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, K331NG
 PL2643484787 AZT, 3TCEFVT215YK103N, V179EV35T, V90I, A98S, K122E, D123S, I135K, S162C, K173I, Q174K, D177K, T200E, I202V, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, V317AT, D324E, I329VG
 PL2750698076 AZT, 3TC, TDF, D4TEFVM41L, D67N, K70R, T215FY, K219KEV179E, Y188LV35K, T39M, K43R, V60I, T69N, A98S, L109LI, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297AITV, D320E, D324E, I329V, Q334QLG
 PL30686101546 AZT, DDI, 3TC, TDFEFVK65KR, L74LVA98AG, K103N, V179E, Y181CV35T, V60VI, K122E, D123S, I135M, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248DN, A272P, T286A, E291D, V292I, I293V, E297A, A304E, D320E, D324E, I329VG
 PL3805585287 D4T, DDI, ABC, AZT, 3TCEFVM184VV179E, Y188FLV35T, K43KR, V60I, A98S, K122E, D123S, I135T, K173AMTV, Q174K, D177E, T200A, Q207K, R211S, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL4110870726 AZT, DDI, 3TC, D4TNVP, EFVD67N, K70R, M184V, K219EK103N, V179EV35T, V60I, A98S, K122E, D123GS, I135T, K173I, Q174K, D177E, T200A, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, A288AT, E291D, V292I, I293V, E297A, L301M, D324E, I329V, Q334PG
 PL4610993794 TDF, DDIEFVK65RK103N, V179E, Y181CV35T, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, I178L, T200V, Q207K, R211S, V245Q, E248D, D250E, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334LG
 PL4689984517 ABC, AZT, 3TCEFVM184VV179E, Y188LV35T, E40D, V60I, K122E, D123S, I135M, K173T, Q174K, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291ED, V292I, I293IV, E297A, V317VA, D320E, D324E, I329V, K331NG
 PL4935891289 AZT, 3TC, DDIEFVM184MIV, T215EK103N, V179EE28K, V35T, K43R, V60VI, W88C, A98S, K122E, D123S, I135T, S163C, K173L, Q174K, D177E, I178M, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL4945091563 TDF, 3TCEFVM184VV106M, V179E, F227FLE28K, V35T, T39A, E40D, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, A288G, V292T, I293V, E297A, K311R, D320E, D324E, I329V, Q334PG
 PL5209098374 AZT, 3TCEFVM184V, T215TSK103N, V179EV35T, K43R, V60VI, A98S, K122E, D123S, I135K, K173IV, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, K311R, I329VG
 PL5238999114 TDF, DDI, 3TCEFVK65R, M184VK103N, V179EE28K, V35T, K43R, V60I, S68SG, A98S, K102KR, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, T200A, Q207E, H221Y, V245Q, E248D, D250E, A272P, T286A, A288AG, E291ED, V292I, I293IV, E297A, D320E, D324E, I329VG
 PL52707100301 D4T, DDIEFVV75ITK103N, V179E, K238TE28K, V35T, I50IV, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293IV, E297A, D320E, D324E, I329VG
 PL44976PL44976 3TC, DDI, D4T, AZTEFVM184VK103N, V179EE28K, V35T, K43R, V60I, A98S, K104KE, K122E, D123S, I135T, Q161K, K173I, Q174K, D177E, T200A, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334LG
Zhong (2007)D005205CN_052EF199585NRTINVPK65RK103N, V179E, Y181CK20R, V35T, T39N, E40D, V60I, K122E, D123N, K173T, Q174K, D177E, I178L, T200A, Q207E, F214L, V245Q, E248DG
Hawkins (2009)P618ZZP618FJ931130D4T, 3TCNVPD67DN, K70KR, M184VV179E, Y181CE6EA, V21VI, V35T, K49KR, V60I, K122E, D123S, I135T, S163T, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, P243S, V245K, D250E, K275Q, T286A, E291D, V292I, I293V, I329V, Q334RG
 P624ZZP624FJ931132D4T, 3TCNVP V179E, Y188YHV35T, V60I, K104R, D121H, K122E, K173T, Q174K, D177E, T200A, Q207E, P243A, V245Q, E248D, D250E, A272S, V276VI, K281R, T286A, E291D, V292I, I293V, S322T, I326VG
 Q227ZZQ227FJ931220AZT, D4T, 3TCNVPM41L, L74LV, M184V, T215YV179E, Y181CV35T, V60I, K103R, K122E, D123S, K173T, Q174K, N175NY, D177E, T200A, E203EK, Q207D, R211K, K223KE, Q242QK, V245Q, E248N, D250E, A272Q, T286A, V292I, I293V, E297K, D324E, I329VG
 Q969ZZQ969FJ931304D4T, 3TCNVPM184V, T215YA98G, V179E, Y181CK20R, V35T, T39K, K103R, K122E, K173T, Q174K, D177E, E194D, G196E, T200A, Q207E, R211K, H221HY, P243S, V245Q, E248D, D250E, S251N, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 Q973ZZQ973FJ931306D4T, 3TCNVPD67N, K70R, M184V, T215TFIS, K219EQV179E, Y181CV35T, K49R, V60I, K103R, K173T, Q174K, D177E, I178M, T200A, Q207D, D218DE, V245Q, E248D, D250E, A272P, T286A, A288T, E291D, V292I, I293VG
 R127ZZR127FJ931334TDF, 3TCEFV, NVPK65R, M184V, K219KEA98G, V108I, V179E, Y181C, M230LP4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329VG
 Q982ZZQ982FJ931373TDF, AZT, D4T, 3TCNVPK65R, V75VA, F77FL, Q151M, M184VV179E, Y181CV35T, T39TAS, E40ED, S68G, A98S, I135L, K173T, D177E, I178M, T200A, Q207X, L210M, R211AEKT, F214FL, V245Q, E248N, D250E, A272P, T286A, V292VI, I293V, E297K, A304E, K311R, I329VG
 R427ZZR427FJ931427AZT, 3TCNVPD67N, K70R, M184V, T215F, K219EV179E, Y181CV35T, T39L, V60I, K103R, K122P, D123N, I135IT, I142V, K173N, Q174K, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, R284RK, T286A, E291D, V292I, I293V, K311R, D324EG
Burda (2010)06ARC03606ARC036GQ344989D4T, 3TC, AZTNVP, EFVM184VK103N, V179E, Y181C, G190AV35T, K43N, K49R, I135V, S162D, E169A, K173A, Q174K, D177E, I178MG
Knops (2010)Pat07Pat07GU991868D4T, 3TCEFVM41L, D67DG, M184V, T215FV179EV21I, V35T, V60VI, S68SG, K104R, K122E, D123S, I135T, I142V, Q174K, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, V276I, L283IT, I293V, E297A, V317A, P321S, D324E, I329V, Q332HG
 Pat17Pat17GU991878DDIEFV, NVPM41L, D67N, T215C, K219QK103N, V108I, V179EK32I, V35R, T39A, V60I, T69N, K102Q, K122E, D123S, I132L, K173R, Q174K, D177E, I178M, E194EA, I195L, G196E, Q197I, T200A, E203D, Q207E, L228H, V245Q, E248D, D250E, A272P, L283I, T286P, E291D, V292I, I293V, E297EK, E302AG