<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 25
Isolates 26
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patRAM02_RAM705AJ577980AZT, Unknown, 3TC, D4TUnknown, EFVK70R, M184VK103N, Y188LW24V, P25A, V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135T, E138A, S162A, K173T, Q174K, T200A, Q207E, F214LG
 MB_patDEL01_DEL725AJ577879AZT, DDI, 3TC, D4T, ABCNVPM41L, D67N, K70R, M184V, T215Y, K219EK103NV35T, T39L, V60I, W88C, K101Q, V118I, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, E203D, Q207D, R211K, F214LG
  02_DEL707AJ577880AZT, DDI, 3TC, D4T, ABC, UnknownNVP, UnknownM41L, D67N, K70R, M184V, T215Y, K219EK103NV35T, T39L, V60I, W88C, V90I, K101Q, V118I, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, E203D, Q207D, R211K, F214LG
Non-B Workgroup (2005)PL3201464894 D4T, DDIEFV  V21I, V35T, T39I, V60I, A98S, K122E, D123N, I135T, E138A, R211RK, A272P, T286A, E291D, V292I, I293V, E297A, I309IVG
 PL3857099368 3TC, D4T, TDF, DDIEFVL74V, K219KDENG190EV35T, S48ST, K49KR, V60I, A98S, K122E, D123NS, I135T, E138A, K173T, Q174K, G196GR, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
Hawkins (2009)Q951ZZQ951FJ931276AZT, D4T, 3TCNVPD67DN, K70R, M184V, K219QV106AV10VI, K20R, K32KI, V35T, T39K, E40D, K49R, V60I, A98AS, K101A, K102KR, K122E, E138A, T165TI, K173KNT, Q174K, D177E, I178L, T200A, Q207E, F214L, V245Q, E248D, D250E, S251H, A272P, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, E328D, I329VG
 R48ZZR48FJ931355AZT, 3TCNVPM41L, D67DN, K70R, M184V, T215F, K219QV106A, G190GA, F227LV35T, V60I, W88C, A98S, K122E, D123G, E138A, I142IV, K173T, Q174R, D177E, I178L, T200A, I202IV, R211K, F214L, H221HY, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, S322T, I329LG
 R265ZZR265FJ931441AZT, 3TCNVPM184VK101KE, V106VA, G190AK20R, V35T, T39N, E40D, K49KR, V60I, I135IT, E138A, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, D250E, S251D, A272P, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329VG
Afonso (2012)ANG69ANG69JN937081NRTINNRTIM184VK101E, K103N, G190AK11T, V35T, T39N, V60I, K122E, D123G, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251NG
 ANG74ANG74JN937086NRTINNRTI  V35T, T39N, E40D, K49R, V60I, V90I, V106I, K122E, D123G, E138A, S162D, K173A, Q174K, V179I, Q207D, R211K, V245QG
 ANG67ANG67JN937079NRTINNRTI K101E, G190AK11S, V35T, T39N, K49R, V60I, K122E, D123R, E138A, S162G, E169D, K173A, Q174K, D177E, I178V, V179I, T200A, I202V, Q207E, V245Q, S251NG
 ANG61ANG61JN937073NRTINNRTIV75L, M184VK101E, G190AK11S, V35T, T39N, V60I, K122E, D123S, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251NG
 ANG58ANG58JN937070NRTINNRTIM184VK101E, G190AK11S, V35T, T39N, V60I, K64R, W88C, K122E, D123S, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, I244V, V245Q, S251NG
Fourati (2012)94505259450525JQ396163NRTINNRTI K103KN, V179VEM16MT, V35T, T39K, D121DH, K122E, D123NT, I135V, E138A, S162C, P170PS, K173A, Q174N, D177DE, I178LM, T200A, Q207N, R211KG
 92105999210599JQ396157NRTINNRTI K103KN, V179VEM16MT, V35T, T39K, D121DH, K122E, I135V, E138A, S162C, K173A, Q174N, D177DE, I178LM, T200A, Q207N, R211KG
Nii-Trebi (2013)KF7KF7AB751480NRTINNRTI  V35T, K43E, K49R, V60I, K102Q, K122E, E138A, Q174E, Q207D, R211K, V245Q, D250E, S251NG
Pircher (2013)B1112B1112JX110213D4T, 3TC, AZTNVPK70E, M184VA98G, V179E, G190SK20R, K22R, V35T, E36K, T39D, E40D, V60I, W88C, K102Q, K122P, E138A, T139V, K173T, Q174K, D177E, T200A, E203K, Q207E, F214L, V245QG
Theys (2013)55935593KC219416TDF, FTCNVPK65R, M184VK101E, Y181C, G190A, M230LV60I, A98S, V106I, K122E, D123T, I135L, E138A, K166R, K173S, Q174R, D177E, I195K, G196E, T200A, R211SG
 89228922KC219624NRTI, TDFNNRTI K101EE40D, K43KR, V60I, A98S, K122E, D123NS, I135T, E138A, T139A, K173IT, Q174K, D177EG, T200A, Q207K, R211SG
 62606260KC219488NRTI, TDFNNRTIM41L, D67N, T215YK103N, Y188LK43N, K49R, V60I, A98S, K122E, D123S, I132V, I135T, E138A, K173T, Q174K, D177E, T200A, Q207K, R211SG
 1038310383KC219759NRTI, TDFNNRTIM184MVK103N, Y188LK43KR, V60I, A98S, S105T, K122E, D123S, I135T, E138A, K173I, Q174K, D177E, T200A, I202V, Q207K, R211SG
 1071110711KC219780NRTI, TDFNNRTI K101EK43KR, V60I, A98S, V106I, K122E, D123NS, I135T, E138A, S162A, E169D, Q174K, T200A, Q207E, R211S, F214L, E224EDG
 1027510275KC219747NRTI, TDFNNRTI  V60I, T69TS, W88C, A98S, K122E, D123N, I135L, E138A, K166KR, K173AV, Q174KR, T200A, Q207K, R211SG
 52605260KC219405NRTI, TDFNNRTI K101E, K103N, G190AK43R, V60I, A98S, K122E, D123S, I135T, E138A, K173T, Q174R, D177E, I178M, V179M, T200A, Q207K, R211SG
 82588258KC219587NRTI, TDFNNRTIK70KQ, M184V V60I, K66KR, A98S, K122E, D123S, I135T, E138A, K173IM, Q174K, T200A, Q207K, R211SG
 37153715KC219295NRTI, TDFNNRTI K103KN, V179EE40D, V60I, S68G, A98S, K122E, D123S, I135T, E138A, T165L, K173T, Q174R, G196E, T200A, Q207K, R211SG