<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation V108I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 34
Isolates 34
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL4294589964 AZT, 3TC, DDIEFVL74V, M184VL100LI, K103N, V108I, V179VEE28EK, V35T, T39L, V60I, A98S, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, K275Q, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
Toni (2005)IC03nvp28IC03nvp28DQ056394NoneNVP V108IV35T, S162A, K173T, Q174K, D177E, T200A, Q207E, Q222QLG
Baxter (2006)48-80118011-30506DQ879056NRTINNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219Q, N348IK101N, V108I, Y181CV8VG, P9PL, K32Q, V35T, T39A, E44D, V60I, V118I, D121H, K122E, I135R, S162DN, K173V, Q174N, D177E, V179VA, T200A, I202V, Q207D, H221Y, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P321S, D324E, I329V, Q334L, G335D, P345Q, F346Y, R356K, M357R, R358G, G359S, A371GV, T386V, K390R, Q394R, E399DG
Hawkins (2009)P612ZZP612FJ931126D4T, 3TCNVPK70R, M184V, K219KQV108I, Y181CV35T, E40D, K122E, D123N, K166KR, K173A, Q174K, D177E, I195T, T200A, E203EAKT, Q207D, L228R, V245Q, E248D, D250T, S251V, K281KR, L283I, T286AV, E291D, V292I, I293V, I326VG
 P910ZZP910FJ931179D4T, 3TCNVPM184VK101E, V108I, Y181CK11KT, V35T, T39M, V60I, K104R, D121H, K122E, D123S, E138Q, K173T, Q174K, D177E, T200A, Q207D, H221Y, V245Q, E248D, D250E, A272P, Q278N, T286A, E291D, V292I, I293V, K311R, D324E, I329VG
 P609ZZP609FJ931183D4T, 3TCNVPM184V, T215FK101E, V108I, Y181CV21I, V35T, V60I, K104R, K122E, D123S, I135RT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, P294QG
 P966ZZP966FJ931187D4T, 3TCNVPM41ML, M184V, T215YV108I, Y181C, G190GAV35T, E40ED, V60VI, K101KQ, L109LI, K122E, D123S, I135L, K173T, Q174K, T200A, Q207D, L228HR, V241I, V245Q, E248N, D250E, T286A, E291D, V292I, I293V, D324EG
 Q191ZZQ191FJ931199D4T, 3TCNVPK70KR, M184VV108I, Y181YC, G190GAV35T, T39N, E40D, V60I, K104R, K122E, D123N, I135IT, K173T, Q174K, D177E, I178M, T200A, E203EK, Q207E, R211K, H221Y, V245Q, E248NS, D250E, A272P, T286A, E291D, V292I, I293V, I329VG
 Q196ZZQ196FJ931203D4T, 3TCNVPV75I, M184V, T215YV108I, Y181CV35T, V60I, L109LI, K122E, D123T, I132L, K173KAET, Q174KR, D177E, I178L, T200A, R211K, H221Y, V245Q, E248N, D250E, A272P, Q278C, T286A, E291D, V292I, I293V, P294T, I329VG
 P950ZZP950FJ931268D4T, 3TCNVPD67N, K70R, M184V, K219EK103N, V108IV35T, T39A, V60I, A98S, D121A, K122E, I135V, K173T, Q174A, D177E, T200A, Q207E, R211K, V245Q, E248N, D250E, A272P, T286A, I293V, P294A, D324E, A327X, E328R, I329VG
 R114ZZR114FJ931310D4T, 3TCNVPM41L, M184V, T215FV108I, Y181CV35T, K49R, D123N, K173T, Q174K, D177E, T200A, Q207D, L228R, K238R, V245Q, E248D, D250E, K281R, T286A, E291D, V292I, I293V, I329VG
 R127ZZR127FJ931334TDF, 3TCEFV, NVPK65R, M184V, K219KEA98G, V108I, V179E, Y181C, M230LP4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329VG
 R150ZZR150FJ931346D4T, 3TCNVPF116Y, Q151M, M184VV108I, Y181CK20K*, V35T, K102R, K104KQ, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, H221Y, P243Q, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297K, I329VG
 R220ZZR220FJ931380AZT, D4T, 3TCNVPM184VK101H, V108I, Y181CK20KR, T27S, V35T, K49R, V60I, S68SG, K122E, D123NS, T139TI, K173A, Q174K, D177E, I178M, T200E, Q207E, R211K, H221Y, L228H, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, D324DEG
 R360ZZR360FJ931417D4T, 3TCNVPD67DG, K70KR, M184V, T215F, K219KEV108I, Y181CK20R, V35T, K49KR, V60I, S68SG, K101X, D121H, K122E, I135R, K173T, Q174K, D177E, I178IM, T200A, Q207E, D218E, V241L, I244IV, V245Q, E248D, D250E, A272P, K275KR, L279LM, T286A, E291D, V292I, I293V, D324X, L325I, I329VG
 R237ZZR237FJ931432TDF, AZT, D4T, 3TCEFV, NVPM184V, T215TNSYK101EQ, V108I, Y181C, G190AV21I, V35T, V60I, K122E, D123N, I135T, K173L, Q174R, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, S251N, A272P, G273N, K275R, K277R, T286A, E291D, V292I, I293VG
 R459ZZR459FJ931434D4T, 3TCNVPM184VK103N, V108IV35T, K49KR, V60I, D123N, I142V, T165K, E169D, K173T, Q174K, D177E, I178L, T200A, Q207D, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, D324E, I329VG
 R479ZZR479FJ931440NRTIEFV, NVPL74V, M184VK103N, V108I, Y181CK11T, V35T, V60I, D121H, K122E, D123S, I135T, I142V, T165ILM, K173T, Q174A, D177E, I178L, I202V, Q207N, L210M, R211K, V245Q, E248DN, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E312G, G316E, Y318C, D320YG
 R269ZZR269FJ931445TDF, AZT, D4T, 3TCNVPK70R, M184V, K219QA98G, V108I, Y181CV35T, V60I, K122E, D123N, I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, F214L, D218E, L228R, Q242QK, V245HQ, E248N, D250E, S251H, A272P, T286A, E291D, V292I, I293V, K311R, I329VG
Burda (2010)06ARC00706ARC007GQ344985D4T, 3TC, AZTNVP, EFVA62V, K65R, V75I, F116Y, Q151M, M184IV108I, Y181CI31L, V35I, S68G, T69I, V90I, K104R, K122E, S162A, K173T, Q174K, D177E, I178MG
Knops (2010)Pat08Pat08GU991869AZT, 3TC, D4T, DDIEFVM41L, D67N, K70R, L74LI, T215F, K219EQK101E, V108I, Y181C, G190A, Y318FK20R, V35I, T39A, K49KR, V60I, K102Q, V118VI, K122E, D123N, I135K, S162D, K173R, I178M, T200A, E204EQ, Q207DE, R211K, D218E, L228H, V245Q, E248ED, D250E, S251G, A272P, L283I, V292I, I293V, E297A, V317A, I329IVG
 Pat17Pat17GU991878DDIEFV, NVPM41L, D67N, T215C, K219QK103N, V108I, V179EK32I, V35R, T39A, V60I, T69N, K102Q, K122E, D123S, I132L, K173R, Q174K, D177E, I178M, E194EA, I195L, G196E, Q197I, T200A, E203D, Q207E, L228H, V245Q, E248D, D250E, A272P, L283I, T286P, E291D, V292I, I293V, E297EK, E302AG
Charpentier (2011)CR-24CR-24FJ688230AZT, 3TCNNRTIM184VK103N, V108IV35T, T39L, K49R, D121H, K122E, I135T, E169D, K173N, Q174K, D177E, T200K, I202V, Q207E, R211K, V245Q, E248D, D250E, S251C, A272P, K275Q, L283I, E291D, V292I, I293V, E297A, S322A, I329VG
Dagnra (2011)08TG.E501108TG.E5011FR715270D4T, 3TCNVPM184VV108I, Y181CK20R, V35T, T39K, E40D, V60I, K122A, D123S, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, S251C, A272P, I274V, T286A, E291D, V292I, I293V, E297P, L301M, K311R, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A360T, D364E, T369AV, A371V, S379AG, T386V, Q394R, A400V, K431TG
Fokam (2011)CIRCB-3194CIRCB-3194JQ796146AZT, 3TCNVPM41L, M184VK103N, V108IK20R, V35T, E40D, K43KR, V60I, K104R, D121H, K122E, E169D, Q174E, D177E, T200A, E203K, Q207A, R211K, K223T, V241M, V245Q, E248D, D250E, S251N, A272P, K277R, Q278H, T286A, E291D, I293V, E297A, L301M, K311RG
Pircher (2013)B1123B1123JX110223D4T, 3TC, AZTNVPM41L, V75M, M184V, L210W, T215YK103N, V108I, Y181CV35T, K49R, V60I, T107S, L109I, D121DN, K122E, D123S, R125RK, E138G, D177E, I178M, Q182QP, T200E, Q207S, R211K, H221Y, V245Q, D250EG
 B1146B1146JX110244D4T, 3TC, AZTNVPM184V, T215YK103N, V108IV35T, V60I, K102Q, D123E, T165L, K173T, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, D250EG
 B1115B1115JX110216D4T, 3TC, AZTNVPM41L, D67G, M184V, T215FA98G, V108I, Y181C, G190AP4S, E6D, L34I, V35T, T39L, E44D, V60I, S68G, K102Q, K122E, D123S, I135T, S162Y, K173T, Q174N, S191SF, I195L, T200A, E203A, Q207E, R211K, F214L, D218E, K219G, H221Y, V245QG
 B1151B1151JX110247D4T, 3TC, AZTNVPD67DN, K70R, M184V, K219KQV108I, Y188W, F227LV35T, T39A, E40D, V60VI, D121H, K122E, I135T, T139KR, K173T, Q174K, D177E, T200A, Q207E, R211RK, H221Y, V245QG
Theys (2013)98569856KC219710TDF, FTCEFVL74V, M184VL100I, K103N, V108IE40D, V60I, A98S, K122R, D123E, I135V, K173T, Q174K, D177E, T200A, Q207K, R211SG
 2567825678KC220366NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 99019901KC219711NRTI, TDFNNRTID67N, K70R, V75M, M184V, T215I, K219EK103N, V108I, Y181YCV60I, A98S, K122E, D123G, I135V, K173T, Q174K, D177E, T200A, Q207K, R211RS, F214L, L228LRG
 5610056100KC221753NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 1404214042KC219796NRTI, TDFNNRTIM184VV108IE40D, V60I, D121H, K122E, K173A, Q174K, D177E, I178L, D192N, L193F, T200A, I202V, Q207E, R211KG