<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation V106I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 25
Isolates 26
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)IL263IL263AY901363AZT, 3TC, D4T, DDINVPM41L, K70KR, F77FL, M184MV, T215TFIS, K219KEV108VI, Y181YCT39K, E40D, V60I, K104R, V106I, K166R, K173I, Q174K, D177E, I178ILM, T200A, Q207E, R211K, F214L, L228LR, V245QG
 PL3679461169AY901566DDC, AZT, 3TC, DDINVPL74VY181CV35T, T39S, K43R, V60I, A98S, V106I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, A304EG
 PL1435061920AY901578AZT, 3TC, D4TEFVM184VY188LV35T, K49R, V60I, A98S, V106I, K122E, D123S, I135T, S162A, K173I, Q174K, D177E, T200E, Q207K, R211S, Y232H, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, D320EG
 PL3916866371AY901632AZT, DDC, 3TC, D4TEFVD67G, K70R, M184V, T215F, K219EK103N, M230LV35T, K43R, V60I, S68G, A98S, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I195M, T200A, Q207K, R211S, L228LH, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334LG
 TK2013TK2013a AZT, 3TC, D4T, ABC, DDIEFVM41L, L74V, M184V, L210W, T215YV179E, Y188LV21I, V35T, E36D, T39A, S48T, V60I, V106I, V118I, E169D, K173R, Q174K, D177E, T200E, Q207E, R211K, T240TM, V245Q, D250E, A272PS, E291D, V292I, I293V, E297KG
  TK2013b AZT, 3TC, D4T, ABC, DDIEFVM41L, L74V, M184V, L210W, T215YV179E, Y188LV21I, V35T, E36ED, T39A, S48T, V60I, V106I, V118I, E169D, K173R, Q174K, D177E, T200E, E203K, Q207E, R211K, T240TM, V245Q, D250E, A272PS, E291D, V292I, I293V, E297K, D324E, I329VG
Baxter (2006)48-43944394-30912DQ878533NRTINNRTIL74V, L210W, T215YK103N, Y181CK20R, I31L, V35T, T39E, E40D, V60I, V90VI, V106I, K122E, D123DGNS, I142V, D177E, G196K, T200A, E203D, Q207E, R211K, L228R, V245Q, D250E, S251N, A272P, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334L, G335E, F346H, K350R, R356K, M357R, R358G, G359S, A360T, A371V, T386V, K390RG
Hawkins (2009)P895ZZP895FJ931169D4T, 3TCNVPD67N, K70R, M184V, K219EQA98G, Y181CK20R, V35T, T39E, E40D, V60I, V106I, I135T, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, H221HY, V245K, E248D, D250E, A272PS, I274V, K275KR, Q278N, T286A, E291D, V292I, I293V, P294T, E297V, L301M, E312G, I329VG
 R358ZZR358FJ931415NRTIEFVY115F, M184VK103N, Y188CK20R, V35A, T39K, E40D, S105T, V106I, V118I, I135T, K173IM, Q174K, D177DE, I178L, T200A, Q207E, L210LQ, R211K, F214L, H221Y, V245Q, E248D, D250E, S251D, A272P, Q278QH, T286A, K287KR, V292I, I293V, E297A, L301M, I329VG
 R361ZZR361FJ931418TDF, 3TCNVPK65R, Y115F, M184VK101E, Y181C, G190AP4L, V35T, V60I, K104KR, V106I, D123S, K173V, Q174K, D177E, T200A, I202V, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I326VG
 R271ZZR271FJ931447TDF, AZT, D4T, 3TCNVPD67N, K70R, M184V, K219EY181CK20R, V35T, T39M, V60I, K104R, V106I, K122E, D123N, I135R, T139I, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, F214L, V245Q, E248S, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, A304E, I329VG
Moussa (2010)2320-CP001266HM117947D4T, 3TCNVPM184V, K219KEA98AG, K103N, Y181CK20KR, V35T, T69TN, K101KR, K102KN, V106I, K122E, D123S, K173A, Q174K, D177E, T200E, I202V, Q207N, R211K, L228HR, P243TG
Afonso (2012)ANG74ANG74JN937086NRTINNRTI  V35T, T39N, E40D, K49R, V60I, V90I, V106I, K122E, D123G, E138A, S162D, K173A, Q174K, V179I, Q207D, R211K, V245QG
Fourati (2012)90300779030077JQ396062NRTINNRTI  V35T, E44D, V60I, K102KQ, V106I, K122E, D123S, I135V, S162Y, K173T, D177E, I178M, S191SF, T200A, Q207N, R211KG
Kouri (2012)CU196-11CU196-11JQ585483NRTINNRTI  V21I, V35T, V60I, K104R, V106I, I135V, K173T, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, L325I, I329V, Q334H, G335DG
Theys (2013)80648064KC219568TDF, FTCEFVD67DG, K70KQ, L74LI, V75VL, M184VK101E, Y181YC, G190SV60I, A98S, V106I, D123N, I135V, E138EA, K166R, K173I, Q174K, D177E, T200A, Q207E, R211RSG
 53995399KC219407TDF, FTCEFVD67G, K70E, M184VL100LI, K101P, K103NE40D, V60I, A98R, V106I, Q174N, T200A, E203EK, Q207EK, R211S, F214FLG
 55935593KC219416TDF, FTCNVPK65R, M184VK101E, Y181C, G190A, M230LV60I, A98S, V106I, K122E, D123T, I135L, E138A, K166R, K173S, Q174R, D177E, I195K, G196E, T200A, R211SG
 20552055KC219147NRTI, TDFNNRTI  K43KR, V60I, S68G, A98S, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, I195L, T200A, Q207E, R211SG
 700700KC219074NRTI, TDFNNRTI Y181IK49R, V60I, A98S, V106I, K122E, D123N, I135T, S162D, K173T, Q174K, D177E, T200A, Q207K, R211SG
 19531953KC219143NRTI, TDFNNRTIK65R, Y115YFK103N, Y181CV60I, A98S, V106I, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, H221YG
 27702770KC219200NRTI, TDFNNRTIM184MIVK103N, Y181YCV60I, V90VI, A98S, V106I, K122E, D123S, I135T, K173I, Q174K, T200A, Q207K, R211SG
 68826882KC219519NRTI, TDFNNRTID67DG, K70E, Y115F, M184VY181CV60I, A98S, V106I, K122E, D123S, I135R, K166R, K173M, Q174K, D177E, T200A, Q207K, R211S, D218DE, H221HYG
 34843484KC219264NRTI, TDFNNRTIK65RK103KT, Y181CK43R, V60I, A98S, V106I, K122E, I135R, T139K, K173I, Q174K, D177E, T200A, Q207E, R211S, F214LG
 1071110711KC219780NRTI, TDFNNRTI K101EK43KR, V60I, A98S, V106I, K122E, D123NS, I135T, E138A, S162A, E169D, Q174K, T200A, Q207E, R211S, F214L, E224EDG
 93819381KC219700NRTI, TDFNNRTIK65RV179E, Y188LV60I, S68G, T69TI, V106I, K122KQ, D123DE, K166KR, K173I, Q174K, D177E, T200A, Q207K, R211SG