<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation K101E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 55
Isolates 55
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patKAF01_KAF715AJ577918AZT, DDI, 3TCEFVD67N, M184V, T215F, K219QK101E, V106MV35T, E36D, T39R, K43E, V60I, K122E, D123N, I135T, A158S, S162A, K173T, Q174K, N175Y, D177E, T200A, I202V, Q207EG
Non-B Workgroup (2005)PL4538780952 AZT, DDI, 3TC, D4TNVPM41L, D67N, M184V, T215F, K219QK101E, G190AE28K, V35T, E36D, T39A, K43R, V60I, D121H, K122E, D123S, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, I329V, K331NG
 PL53397101698 NRTIEFVK65R, Q151M, M184IK101E, Y181C, M230LV35T, S68G, V90VI, A98S, K122E, D123S, I135R, I167IV, K173R, Q174K, D177E, I195IL, T200A, I202V, R211S, D237A, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, D324E, L325I, I326V, I329VG
 PL881592822 AZT, 3TC, D4T, DDINVPD67N, K70R, T215Y, K219EK101E, Y181CE28K, V35T, K43R, V60I, A98S, K122E, D123S, K173IM, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
Baxter (2006)48-12511251-30602DQ877776NRTINNRTIM41L, D67N, K70R, V75M, L210W, T215YA98G, K101E, G190AE28K, K32E, V35T, T39A, E44D, V60I, V118I, K122E, I135V, S162C, K173T, Q174K, N175Y, D177E, T200A, E203D, Q207K, R211EK, K223Q, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, S379A, I382M, Q394R, K395RG
Hawkins (2009)P607ZZP607FJ931124D4T, 3TCNVPL74LV, M184VK101E, G190AK20R, E28K, K32KE, V35T, T39N, W88C, L109LI, K122E, I142V, K173A, Q174K, D177E, I178L, Q197QK, T200A, K201KR, E204EK, Q207EV, R211K, F214L, V245Q, E248D, D250E, S251A, A272P, T286A, E291ED, V292I, I293V, E297A, L301M, P321S, D324E, E328D, I329VG
 P636ZZP636FJ931142D4T, 3TCNVPM184VK101E, G190AK20R, E28K, V35T, V60I, K122E, D123E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, P243H, V245E, E248D, K275R, T286A, E291D, V292I, I293V, P294T, V317A, S322T, I326VG
 P648ZZP648FJ931152D4T, 3TCNVPD67N, K70R, M184V, K219QA98G, K101E, G190AK20R, E28K, K32E, V35T, T39N, V60I, K122E, K166R, K173T, Q174N, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329VG
 P904ZZP904FJ931178D4T, 3TCNVPM184VK101E, K103KNE28K, V35T, V60I, A98S, K122E, D123G, K173T, Q174K, D177E, I178M, I195IT, T200A, Q207D, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293VG
 P910ZZP910FJ931179D4T, 3TCNVPM184VK101E, V108I, Y181CK11KT, V35T, T39M, V60I, K104R, D121H, K122E, D123S, E138Q, K173T, Q174K, D177E, T200A, Q207D, H221Y, V245Q, E248D, D250E, A272P, Q278N, T286A, E291D, V292I, I293V, K311R, D324E, I329VG
 P609ZZP609FJ931183D4T, 3TCNVPM184V, T215FK101E, V108I, Y181CV21I, V35T, V60I, K104R, K122E, D123S, I135RT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, P294QG
 P623ZZP623FJ931184D4T, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AE28EAKT, V35T, V60I, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, K275KR, V276I, K277R, T286A, E291D, V292I, I293V, P294T, E297K, D324E, I329VG
 Q200ZZQ200FJ931205D4T, 3TCNVPD67N, K70R, M184V, T215TFIS, K219QK101E, G190A, Y318FE28K, K32KI, V35T, V60I, T69N, K104R, K122E, D123S, K173IR, Q174K, N175Y, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251N, T286A, E291D, V292I, I293V, E297AG
 Q86ZZQ86FJ931221D4T, 3TCNVPM184VK101E, G190AK20R, V21VI, V35T, T39K, E40D, V60I, K104R, K122E, D123N, K173T, T200A, E203D, Q207N, R211K, F214L, V245Q, E248N, D250E, S251V, A272P, Q278H, K281R, E291D, V292I, I293V, E297T, L301M, A304E, I329VG
 Q198ZZQ198FJ931227D4T, 3TCNVPM184V, T215YA98G, K101E, Y181CV21I, V35T, V60I, K122E, D123S, I135T, T165L, K173A, Q174K, D177E, I178M, G196E, T200A, Q207E, V241I, V245Q, E248D, D250E, S251N, A272S, T286A, E291D, V292I, I293V, K311KR, D324E, I329VG
 Q789ZZQ789FJ931247D4T, 3TCNVPM184VK101E, G190AE28EK, K32R, V35T, V60I, K102R, K122E, D123G, K173T, Q174K, D177E, T200A, E203EK, Q207E, V245Q, E248N, D250E, A272P, L279M, T286A, E291D, V292I, I293V, D324E, I329VG
 Q977ZZQ977FJ931282AZT, D4T, 3TCNVPM184V, T215FK101E, G190AE28K, V35T, V60I, S68SG, V106VI, K122E, I135L, S162A, K173T, Q174K, N175NY, D177E, T200A, Q207E, R211K, V245K, A272P, T286A, E291D, V292I, I293V, I329VG
 R52ZZR52FJ931297TDF, 3TCNVPK65R, M184IK101E, Y181C, M230MLE28K, K32E, V35T, E40D, K49R, I50V, V60I, W88WC, A98S, K122E, I135V, S162C, K166KR, E169D, K173R, Q174N, D177E, I178L, T200A, Q207E, V245Q, D250E, S251H, T286A, E291D, V292I, I293V, E297A, P321S, D324E, I329VG
 Q949ZZQ949FJ931323D4T, 3TCNVPM41L, M184V, T215FYA98G, K101E, G190AE28K, V35T, V60I, K173T, Q174K, D177E, I178M, T200A, Q207D, V245Q, S251N, A272S, T286A, E291D, V292I, I293V, K311R, E312K, D324E, I329VG
 R26ZZR26FJ931343TDF, AZT, D4T, 3TCNVPK65R, K70KT, M184VK101E, Y181C, G190AV35T, V60I, S68SKNR, K102Q, V111VI, D121H, K122E, D123S, I135V, E138Q, S162A, K173A, Q174K, D177E, T200A, Q207QK, F214FL, V245Q, E248DN, D250DGNS, S251SN, A272P, T286A, E291D, V292I, I293V, P294TG
 R107ZZR107FJ931358TDF, 3TCNVPA62AV, K65R, M184VK101E, Y181C, G190SV35T, S68SG, D123E, S162A, K173A, Q174K, D177E, T200A, Q207E, R211RK, V245Q, D250E, A272AP, E291D, V292I, I293V, E297K, I329VG
 R222ZZR222FJ931381NRTIEFV, NVPM184VK101E, K103N, G190AV35T, T39L, K122E, D123S, K173A, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, D324E, I329VG
 R258ZZR258FJ931403AZT, 3TCNVPD67N, K70R, M184V, K219QK101E, G190AK20R, V35T, I50IV, V60I, W88C, K104R, K122E, D123N, E138Q, I142V, K166R, K173T, Q174R, D177E, I178M, T200A, Q207E, R211S, F214L, V245Q, E248D, D250E, S251N, A272P, K277R, K281R, T286A, E291D, V292I, I293V, P321S, D324E, I329VG
 R367ZZR367FJ931405D4T, 3TCEFV, NVPM184V, T215YA98G, K101E, V108VI, Y181C, G190AK20R, E28K, K32KE, V35T, K49R, V60I, K104R, K122E, I135V, T139TI, K173IM, Q174K, D177E, T200A, Q207G, R211K, V241VI, V245Q, E248D, D250E, S251I, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I309IM, S322SA, I329VG
 R369ZZR369FJ931407AZT, D4T, 3TCNVPM184VK101EE28EGKR, V35T, K49R, V60I, V90I, K122E, D123S, I135V, T165I, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214L, V245Q, E248N, D250E, A272P, T286A, E291D, I293V, P294T, I326VG
 R361ZZR361FJ931418TDF, 3TCNVPK65R, Y115F, M184VK101E, Y181C, G190AP4L, V35T, V60I, K104KR, V106I, D123S, K173V, Q174K, D177E, T200A, I202V, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I326VG
 R239ZZR239FJ931433AZT, 3TCNVPM41ML, D67N, K70R, M184V, T215F, K219EA98G, K101E, Y181C, G190AE28EK, V35T, V60I, T69N, K104R, K122E, D123N, K173T, Q174R, D177E, T200A, I202V, Q207E, F214L, L228H, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, I329VG
 R443ZZR443FJ931454NRTINVPM184VA98G, K101E, E138KQR, G190AV21VI, V35T, T39IM, E40D, V60I, W88WC, K104R, K122E, D123S, I132IV, I135T, K173T, Q174K, V179I, T200A, I202V, Q207D, R211K, F214L, V245Q, D250E, S251H, A272P, T286A, E291D, V292I, I293V, E297K, S322G, D324EG
Knops (2010)Pat08Pat08GU991869AZT, 3TC, D4T, DDIEFVM41L, D67N, K70R, L74LI, T215F, K219EQK101E, V108I, Y181C, G190A, Y318FK20R, V35I, T39A, K49KR, V60I, K102Q, V118VI, K122E, D123N, I135K, S162D, K173R, I178M, T200A, E204EQ, Q207DE, R211K, D218E, L228H, V245Q, E248ED, D250E, S251G, A272P, L283I, V292I, I293V, E297A, V317A, I329IVG
 Pat14Pat14GU9918753TC, DDINVP, EFVM41L, D67N, L74LV, L210W, T215Y, K219KEK101E, Y181C, G190AP1PA, V35T, T39TA, V60I, K102Q, K104KR, V118VI, K122E, D123S, I135T, E138T, K173N, Q174K, D177E, I178M, S191SCW, I195IM, T200A, E203EK, Q207D, R211K, D218DE, V245Q, E248D, D250E, A272P, L283I, V292I, I293IV, E297A, D324E, I329VG
Charpentier (2011)125CP 001 949 D4T, 3TCNVPM184VA98G, K101E, G190AV35T, T39N, E40D, V60I, K104R, K122E, D123N, I135V, I142V, K173T, D177E, T200A, Q207A, R211K, D237DE, V245Q, E248N, A272P, K281R, E291D, V292I, I293V, E297A, E312N, V317A, P321S, D324E, I329V, Q334EG
Afonso (2012)ANG69ANG69JN937081NRTINNRTIM184VK101E, K103N, G190AK11T, V35T, T39N, V60I, K122E, D123G, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251NG
 ANG67ANG67JN937079NRTINNRTI K101E, G190AK11S, V35T, T39N, K49R, V60I, K122E, D123R, E138A, S162G, E169D, K173A, Q174K, D177E, I178V, V179I, T200A, I202V, Q207E, V245Q, S251NG
 ANG61ANG61JN937073NRTINNRTIV75L, M184VK101E, G190AK11S, V35T, T39N, V60I, K122E, D123S, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251NG
 ANG58ANG58JN937070NRTINNRTIM184VK101E, G190AK11S, V35T, T39N, V60I, K64R, W88C, K122E, D123S, E138A, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, I244V, V245Q, S251NG
Rawizza (2013)PJ7081PJ7081KF241505NRTINNRTIM41L, D67N, K70R, V75VIM, M184V, T215FY, K219EQK101E, G190AE28K, V35T, T39M, V60I, K173A, Q174K, T200A, I202V, E203EK, Q207E, V245Q, E248D, D250E, S251N, A272P, K281R, T286TA, E291D, V292I, I293V, I329VG
 OU8939OU8939KF241475NRTINNRTIM41L, D67N, K70R, V75M, M184V, T215F, K219QK101EP9PQ, V35T, T39A, V60I, T69N, V118I, K122E, D123S, I135R, Q174E, D177E, I178M, T200A, E204K, Q207E, F214L, V245Q, E248N, D250E, A272P, E291D, V292I, I293V, P294T, K311KT, D324E, I329VG
 PJ6799PJ6799KF241495NRTINNRTIM41L, D67DG, T69AD, K70R, M184MV, L210LWK101E, Y181C, G190AE28K, V35T, T39L, V60I, K104R, V118VI, D121Y, K122E, I135IT, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, T215X, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292VI, I293V, I329VG
Theys (2013)1062010620KC219765TDF, FTCEFVK70KT, L74I, Y115YF, M184VK101E, V179EQ, G190S, P225HK49R, V60I, V90I, A98S, D121HY, K122E, E138G, I142IT, S162SN, Q174A, D177E, I178IM, I195K, T200AG
 66886688KC219504TDF, FTCNVPL74I, M184VK101E, G190AV60I, A98S, K122E, D123S, I135L, E169D, K173R, Q174K, V189VI, E194EQ, I195K, G196DE, T200A, E203EK, R211KG
 80648064KC219568TDF, FTCEFVD67DG, K70KQ, L74LI, V75VL, M184VK101E, Y181YC, G190SV60I, A98S, V106I, D123N, I135V, E138EA, K166R, K173I, Q174K, D177E, T200A, Q207E, R211RSG
 33323332KC219253TDF, 3TCNVPM184VK101E, V106A, E138K, F227LV60I, A98S, K122E, D123S, I135T, I142V, R172K, K173I, Q174K, D177E, T200A, I202V, Q207G, R211SG
 55935593KC219416TDF, FTCNVPK65R, M184VK101E, Y181C, G190A, M230LV60I, A98S, V106I, K122E, D123T, I135L, E138A, K166R, K173S, Q174R, D177E, I195K, G196E, T200A, R211SG
 35733573KC219278NRTI, TDFNNRTID67G, K70R, M184V, T215F, K219EK101E, E138KE40D, K43R, V60I, S68G, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, I178IV, I195L, T200A, I202V, Q207K, R211RS, F214L, L228LHG
 78487848KC219561NRTI, TDFNNRTI K101EK43R, V60I, A98S, K122E, D123NS, I135T, A158AT, S162CY, K173T, Q174K, D177E, T200A, Q207K, R211SG
 45764576KC219378NRTI, TDFNNRTIM184IK101EE40D, V60I, A98S, K122E, D123S, I135R, T165I, K173I, Q174K, D177E, T200A, Q207K, R211SG
 59015901KC219453NRTI, TDFNNRTIA62V, V75I, M184V, K219NK101E, Y181C, G190SK43KR, A98S, K122E, D123S, K173V, Q174K, D177E, T200A, Q207G, R211KG
 93419341KC219691NRTI, TDFNNRTID67N, K70E, M184VK101E, G190AK43E, V60I, A98S, K103KR, K122E, D123S, I135T, K173T, Q174K, D177E, V189I, T200A, Q207K, R211SG
 39743974KC219328NRTI, TDFNNRTIM41L, L74LI, M184V, T215FK101E, Y181C, G190AV60I, W88WS, A98S, D121H, K122E, K173I, Q174K, D177E, Q207E, R211RS, L228RG
 89228922KC219624NRTI, TDFNNRTI K101EE40D, K43KR, V60I, A98S, K122E, D123NS, I135T, E138A, T139A, K173IT, Q174K, D177EG, T200A, Q207K, R211SG
 99369936KC219713NRTI, TDFNNRTID67G, K70R, M184V, T215I, K219EK101E, V179E, P225HE40D, K43R, V60I, S68G, A98S, K122P, D123S, I135R, S162A, K173R, Q174K, D177E, I195K, G196E, Q197P, T200A, R211SG
 89378937KC219626NRTI, TDFNNRTIM41L, L74V, T215CK101E, Y181C, G190SV60I, A98AS, D121H, K122E, D123S, I135V, K173T, Q174K, D177E, T200A, Q207K, R211SG
 1071110711KC219780NRTI, TDFNNRTI K101EK43KR, V60I, A98S, V106I, K122E, D123NS, I135T, E138A, S162A, E169D, Q174K, T200A, Q207E, R211S, F214L, E224EDG
 52605260KC219405NRTI, TDFNNRTI K101E, K103N, G190AK43R, V60I, A98S, K122E, D123S, I135T, E138A, K173T, Q174R, D177E, I178M, V179M, T200A, Q207K, R211SG
 92559255KC219669NRTI, TDFNNRTID67GK101E, Y181CE53ED, V60I, T69N, K122E, D123S, I135L, I142V, S162A, Q174K, D177E, E194ED, T200A, Q207K, R211SG