<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 3
Patients 40
Isolates 40
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL1618161896AY9015723TC, D4T, ABC, DDINVP, EFVL74V, M184VL100I, K103NV35T, V60I, A98S, K122V, D123N, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297AG
 PL2647363176AY901588AZT, 3TC, DDI, ABCEFVM41L, D67N, K70R, L74V, M184V, T215F, K219QL100I, K103NV35T, S48SL, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, D218DE, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301MG
 PL3650878607 D4T, DDIEFVL74LV, K219KNL100I, K103NV35K, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, R211RKNS, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, T296S, E297A, D320E, D324E, I329VG
 PL4092370238 DDC, AZT, DDI, D4TEFVL74VL100I, K103NV35T, K43R, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200A, Q207KT, R211S, H221HY, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, I293IV, E297A, V317VA, I329LG
 PL45525102251 ABC, 3TC, TDFEFVK65R, Y115F, M184VL100I, K103NV35T, K46Q, K49R, V60I, A98S, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL48170102151 AZT, 3TC, D4TEFVA62AV, F116Y, Q151M, M184VL100I, K103NV35I, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, I202V, Q207K, R211S, F214FL, L228R, V245Q, E248D, D250E, A272P, V276VI, T286A, V292I, I293V, E297T, D320E, D324E, I329V, Q334LG
 PL5064994673 TDF, 3TCEFVL74V, M184VL100I, K103NV35I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, R211S, V245Q, D250E, A272P, K275Q, T286A, E291D, V292T, I293V, E297A, L301M, D320E, D324E, I329VG
 PL5178697581 3TC, D4T, AZT, DDIEFVM41L, D67GS, K70R, T215F, K219EL100I, K103NV35T, K43R, V60I, T69N, V90VI, A98S, K122E, I135T, K166KR, K173I, Q174K, D177G, T200A, E203EK, Q207EK, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
 PL5238899113 D4T, DDI, 3TCEFVL74V, M184VL100I, K103NE28EK, V35IT, E36ED, T39TA, K43R, V60VI, T69TN, A98S, K122E, D123S, I135T, K166KR, K173I, Q174K, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, V276VI, K277KR, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL52777100126 TDF, DDIEFVK65KRL100I, K103NV35T, V60I, A98S, D121H, K122E, S134SR, I135V, Q174E, D177E, I195K, T200A, V245Q, E248D, D250E, A272P, V276I, Q278H, L283I, T286A, E291D, V292I, I293V, E297A, D320E, D324EG
Toni (2005)IC03nvp2IC03nvp2DQ056375NoneNVP L100IK32R, V35T, V90G, D123E, I135V, K173T, Q174K, D177E, T200A, Q207E, R211KG
Theys (2013)98569856KC219710TDF, FTCEFVL74V, M184VL100I, K103N, V108IE40D, V60I, A98S, K122R, D123E, I135V, K173T, Q174K, D177E, T200A, Q207K, R211SG
 76067606KC219551TDF, FTCEFVL74V, M184VL100I, K103NV60I, A98S, K122E, D123N, I135T, Q174K, D177E, T200A, R211NG
 29732973KC219218TDF, 3TCEFVK65R, V75I, M184IL100I, K103NV60I, A98S, K122E, D123S, I132L, K173I, Q174K, D177G, T200A, Q207K, R211SG
 40504050KC219336TDF, FTCEFVK65R, M184VL100I, K103NK43R, V60I, K64R, A98S, K122E, D123S, I135T, K173V, Q174K, D177E, T200A, Q207G, R211S, F214LG
 28902890KC219211TDF, 3TCEFVL74V, M184VL100I, K103NA98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, R211SG
 41604160KC219346TDF, FTCEFVK65KR, L74LI, M184VL100I, K103N, P225PHV90VI, K122E, D123N, I135L, K166R, R172RK, K173R, Q174D, D177E, T200A, Q207K, R211SG
 93189318KC219682TDF, FTCEFVK65R, K70T, M184VL100I, K103NK64R, S68N, A98S, K122E, D123S, I135T, K173IT, Q174N, T200A, Q207K, R211SG
 37253725KC219297TDF, 3TCEFVK65KR, L74LV, V75VIM, M184V, K219EL100I, K103NK43R, V60VI, S68SR, A98S, D123E, K173I, Q174K, D177E, T200A, Q207K, R211SG
 45754575KC219377TDF, FTCEFVL74V, M184V, K219EL100I, K103NV60I, A98S, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178L, V189I, T200E, E204D, Q207KG
 43644364KC219362NRTI, TDFNNRTIK65R, L74LI, M184VL100I, K103NK43R, A98S, K122E, D123S, K166R, K173I, Q174K, D177E, T200A, Q207K, R211NG
 2567825678KC220366NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 1062110621KC219766NRTI, TDFNNRTIK65R, M184VL100I, K103NK43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207EK, R211SG
 73957395KC219544NRTI, TDFNNRTIK65RL100I, K103NV60I, A98S, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, Q207K, R211SG
 61946194KC219477NRTI, TDFNNRTIL74V, M184VL100I, K103NV60I, V90I, K122E, D123S, I135V, S162F, S163N, K173T, Q174K, N175Y, D177E, T200AE, R211K, H221YG
 14771477KC219126NRTI, TDFNNRTIK65R, M184IV, K219NL100I, K103NK49R, S68G, V90I, A98S, K122E, S162D, K173T, Q174K, D177E, T200A, Q207K, R211SG
 25522552KC219184NRTI, TDFNNRTIK65RL100I, K103NV60I, A98S, K122E, D123S, I135T, K173T, Q174K, T200A, I202V, Q207EG
 5610056100KC221753NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219QA98G, L100I, K103N, V108IV60I, K104R, V118I, K122E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, F214LG
 31063106KC219230NRTI, TDFNNRTIK65KRL100I, K103NV60I, A98S, D121H, K122E, S134SR, I135V, Q174E, D177E, I195K, T200AG
 39363936KC219321NRTI, TDFNNRTIL74V, M184VL100I, K103NK43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200V, R211NSG
 618618KC219068NRTI, TDFNNRTIK65R, M184VL100I, K103NV60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, I178L, T200A, Q207K, R211SG
 35533553KC219273NRTI, TDFNNRTIK65R, L74V, K219RL100I, K103NE40D, K43R, V60I, S68G, T69N, A98S, K122E, D123S, S134C, I135T, A158S, S162A, Q174K, D177E, T200A, Q207K, R211S, F214L, H221YG
 36633663KC219292NRTI, TDFNNRTIK65R, Y115FL100I, K103NE40K, K43R, P52PR, N57EK, V60I, N81ND, A98S, K122E, D123S, I135R, E169E*, K173R, Q174K, D177E, T200A, R211SG
 62746274KC219490NRTI, TDFNNRTIL74V, M184VL100I, K103NK46Q, V60I, A98S, D121H, K122E, D123S, I135T, K173L, Q174K, D177E, T200E, Q207K, R211SG
 56875687KC219427NRTI, TDFNNRTIM41L, D67N, M184V, L210W, T215Y, K219NL100I, K103NK43KR, V60I, V118I, K122E, D123N, I135T, S162N, K166R, K173I, Q174K, D177E, T200A, I202V, Q207K, R211D, L228HG
 36313631KC219285NRTI, TDFNNRTIK65R, L74LVL100I, K103NK43R, K49R, V60I, K64R, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, F214FLG
 56895689KC219429NRTI, TDFNNRTIM41L, M184V, T215YL100I, K103NS48ST, F87FL, K122E, D123S, I135T, K173I, Q174K, D177E, Q197QL, T200A, Q207K, R211D, L228RG
 926926KC219092NRTI, TDFNNRTIM41L, D67N, K70R, L74V, M184V, T215Y, K219EL100I, K103NV60I, A98S, K122E, D123S, K173IM, Q174K, D177EG, T200A, Q207K, R211N, L228HG
 32043204KC219238NRTI, TDFNNRTIK65KR, K70GR, L74V, Y115F, M184V, K219KEL100I, K103NV60I, S68SG, A98S, K122E, D123S, I135T, K173L, Q174K, D177E, T200A, Q207K, R211S, L228LRG
 13941394KC219120NRTI, TDFNNRTIM41L, K70KE, L74V, M184VL100I, K103NK43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, R211S, L228RG