<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation A98G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 19
Isolates 19
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Dumans (2004)RES093RES093AY390211AZT, 3TC, DDI, UnknownEFV, UnknownM41L, L74I, M184V, L210W, T215YA98G, K103N, V108IK20KR, V35T, E44D, V118I, K122E, I135L, S162F, E169D, K173A, Q174K, T200A, E203K, Q207E, R211Q, K223E, V245Q, E248DF
 RG008RG008AY390204AZT, 3TC, D4T, DDI, UnknownEFV, UnknownD67N, K70R, M184V, T215F, K219EA98G, Y181CV35T, T39G, K49R, I135V, S162C, E169D, K173A, Q174K, D177E, G196E, T200A, Q207E, R211K, V245Q, P247A, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E297A, S322T, I329LF
Rodrigues (2005)BLF_Pat6BR03SP164AY643237AZT, Unknown, DDI, 3TC, D4TUnknown, NVPM41L, L210W, T215YA98G, K101HQ, Y181CP4PT, V35I, K43KE, E44D, K49R, V118VI, K122E, I135T, S162C, E169D, K173A, Q174K, E203K, Q207D, R211KT, K223Q, L228R, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297AV, V317A, S322AF
 BLF_Pat8BR03SP01AY643229AZT, 3TC, UnknownUnknown, NVPM41L, D67N, K70R, L74I, M184V, T215YA98G, K101E, G190AS3C, E6D, K20R, V35T, E44D, K49R, I135V, E138A, S162C, E169D, K173A, Q174K, I178L, T200E, E203K, Q207E, H208Y, R211K, K223E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, V317AF
 BLF_Pat17BR02SP88AY643228AZT, DDI, 3TC, D4TNVP, DLVM41L, D67N, K70R, L74I, V75S, M184V, T215Y, K219EA98G, K103N, V108IE6K, K20R, K32R, V35T, T39A, E44D, V118I, K122E, S162Y, E169D, K173A, Q174K, T200A, E203K, Q207E, H208Y, W212WL, K223E, L228H, Q242H, V245Q, E248D, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297T, D324E, Q334EF
 BLF_Pat18BR03SP130AY643233AZT, 3TC, D4TNVPK70KR, M184V, K219KEA98G, Y181CV35T, V118I, D121H, K122E, E169D, K173A, Q174K, D177E, I178L, V179VI, T200A, Q207E, R211K, F214L, L228LH, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, E297A, I329LF
 BLF_Pat21BR02SP235AY643217AZT, DDI, 3TC, D4T, UnknownEFV, UnknownM41L, D67N, K70R, M184V, T215F, K219EA98GV35T, T39A, T69N, V118I, K122E, I135T, S162A, F171Y, K173A, Q174K, Q207E, R211K, F214L, L228H, V245Q, E248D, A272PF
Baxter (2006)48-32663266-30729DQ878171NRTINNRTID67N, K70R, L74I, M184V, T215F, K219QA98G, K103S, Y181C, G190AP4S, K20KR, V35T, T69N, K122E, D123E, I135L, E138EQ, T165I, I167V, E169EQ, K173A, Q174K, D177E, I178L, V179T, T200A, I202V, E204A, Q207E, R211K, D218E, P243T, V245Q, E248D, D250S, A272P, K275R, T286A, E291D, I293V, E297A, L303M, D324DE, I329V, F346H, R356RK, M357R, G359S, K366R, A371V, S379G, T386I, K390R, E399DF
 48-61786178-30731DQ878750NRTINNRTIM41L, D67N, T69D, L74IV, M184V, T215YA98G, V108VIM, Y181C, G190AS3C, K20R, V35T, E44D, K101KQ, D123E, I135V, S162C, I167IV, E169D, R172RK, K173A, Q174K, I178L, Q207E, R211K, D218E, H221HY, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297A, E328D, R356K, G359S, T377L, K390R, Q394L, E399DF
 48-92669266-30915DQ880860NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215Y, K219RA98G, V108I, F227FLT39M, E44D, V118I, K122E, I135T, I142V, S162Y, E169D, K173A, Q174K, I178IM, E203K, Q207E, H208Y, R211K, K223E, L228H, P243S, V245QF
Dumans (2009)192192FJ405073AZT, DDI, DDC, Unknown, D4T, 3TCUnknown, EFVM41L, L74I, M184V, L210W, T215YA98G, K103N, V108IE44D, L109LP, V118I, K122E, D123E, I135L, I142T, E169D, K173A, Q174K, V179I, T200A, Q207E, H208Y, R211K, L228H, V245Q, E248D, A272P, I293V, E297AF
 RENA626RENA626FJ405172AZT, 3TC, D4T, ABC, DDINVP, DLVM41L, D67N, K70R, L74I, V75S, L210W, T215Y, K219EA98G, K103N, V108IE6K, K20R, K32R, V35T, T39A, E44D, V118I, K122E, E138G, S162Y, E169D, K173A, Q174K, T200A, E203K, Q207E, H208Y, W212M, K223E, F227FY, L228H, Q242H, V245Q, E248D, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297T, D324E, Q334EF
Charpentier (2011)CR-5CR-5FJ688212AZT, 3TCNNRTIM41ML, D67DN, Q151QKLM, M184V, L210LW, T215YA98G, K103NK20R, K32I, V35T, T39K, K43KE, V60VI, S68SG, V118VI, I135L, S162AD, K173A, Q174K, D177E, I178IL, G196GE, Q207DEKN, R211K, D237DE, P243PA, V245Q, E248D, D250S, A272P, Q278Y, K281R, T286A, E291D, I293V, E297A, I326IV, Q334DF
Fokam (2011)CIRCB-10183CIRCB-10183JQ796165D4T, 3TCNVPM184V, K219KNA98G, Y181CV35T, D123E, K173A, Q174KR, D177E, T200TA, Q207A, R211T, V245Q, E248D, D250DE, A272P, K275R, K277R, Q278H, T286A, E291D, I293V, E297P, L310IF
Jones (2012)130299130299JN669482NRTINNRTIM41L, L210W, T215YA98G, Y181CE6D, K20R, L34LV, V35T, K49R, D123E, I135V, S162C, E169D, K173A, Q174K, T200A, Q207D, R211K, V241M, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, D324E, F346Y, R356K, G359S, A360T, T377V, Q394L, E399DF
Kouri (2012)CU344-10CU344-10JQ585386NRTINNRTIM41L, M184V, T215FA98G, K103N, K238TK20KR, V35T, V60I, K122P, D123E, I135L, Q174K, D177E, I178M, V179VI, T200A, Q207E, R211K, F214L, D237N, V245Q, A272P, V276T, L283I, I293V, E297AF
 CU737-10CU737-10JQ585413NRTINNRTIM41L, K70KI, L74V, M184V, T215FA98G, V108I, Y181CV35T, E44D, K122P, I135T, Q174E, D177E, G196GE, Q207K, R211T, F214L, V245Q, A272P, K275R, V276I, L283I, T286A, E291D, I293V, E297A, I326IV, Q334Y, G335DF
 CU599-10CU599-10JQ585404NRTINNRTIM41L, D67S, T69S_RG, K70R, F77FL, M184V, T215F, K219EA98G, K101E, V108I, Y181C, G190AE28K, K32E, V35T, V60I, S68G, V106I, L109V, V118I, K122P, D123E, I135V, I159L, D177E, I180IM, Q207E, R211K, F214L, D218E, L228H, V245Q, A272P, V276T, K277R, L283I, T286A, A288T, V292I, I293V, E297AF
Pircher (2013)B1152B1152JX110248D4T, 3TC, AZTNVPM41L, D67N, K70R, V75VL, M184V, T215F, K219QA98G, K101E, G190AE6D, K11Q, E28K, K32E, V35T, T39M, K43N, V60I, T69S, K122E, D123N, F171Y, K173T, Q174K, D177E, I178M, V179VI, R211K, L228Q, V245Q, E248N, D250EF