<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation P225H
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Apetrei (2003)AC_Pat20RO.01.IS.20AY333577AZT, 3TC, D4TEFV K103N, P225HV35T, T39A, E40D, D123E, I135L, S162H, K173A, Q174K, T200A, Q207A, R211KF
 AC_Pat25RO.01.IS.25AY333552AZT, 3TC, D4TEFV K103N, P225HV35T, T39A, W88C, K101Q, D123E, I135L, E138G, S162H, K166Q, Q174R, D177E, I195L, G196K, T200A, Q207A, R211KF
 AC_Pat40RO.00.IS.40AY333600AZT, 3TCEFVD67N, T69D, K70R, K219QK103N, P225HT39A, I135L, S162Y, K173T, Q174K, I195L, T200A, Q207T, R211KF
 AC_Pat73RO.01.IS.73AY333553NRTI, UnknownNNRTI, UnknownK219RK103N, V106A, P225H, F227LV35T, V60I, S105T, D123E, I135L, S162H, K173T, Q174K, P176A, V189I, I195L, G196E, T200A, I202V, Q207A, R211K, L228RF
Waleria-Aleixo (2008)08PR05037908PR050379FJ591404NRTINNRTI K103N, P225HV35T, T39L, D123E, S162C, E169D, K173A, Q174K, Q207E, R211K, L228R, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297AF
 08RJ06053408RJ060534FJ591726NRTINNRTIM184V, K219RK103N, V108I, P225HK20R, V35T, T39L, V60I, I135V, E169D, K173A, Q174K, T200A, Q207A, R211K, V245Q, E248D, A272P, T286V, E291D, V292I, I293V, P294T, E297TF
Dumans (2009)RENA569RENA569FJ405166AZT, DDI, Unknown, 3TC, D4TUnknown, EFV K103N, P225HE28K, K32E, V35T, T39L, E40ED, K49R, D123E, I135T, S162C, E169D, K173A, Q174K, I178L, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, V317AF
Rodrigues (2010)310_07BR07SC310GQ401318AZT, 3TCEFVM184MIK103N, P225HE6N, I31L, V35T, V90VI, K122E, S162C, K173IT, Q174K, Q207E, R211K, V245Q, D250E, A272P, K277Q, T286A, E291D, V292I, I293V, E297AF
Charpentier (2011)CR-35CR-35FJ688241AZT, 3TCNNRTIM41L, T69S_SG, V75I, M184V, T215YK103N, P225HI31L, K32R, V35T, T39M, K43KR, W88A, I132L, S162Y, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, L228H, V245Q, E248D, D250E, S251H, K281R, V292I, I293V, P294T, E297K, A304E, S322AF
Theys (2013)120274120274 AZT, 3TCEFVM184VK103N, P225H, K238TK20R, V35T, T39A, I135V, S162C, K173A, Q174K, T200A, Q207E, R211A, P243Q, V245Q, E248D, D250E, A272P, K281R, T286A, E291D, V292I, I293V, E297AVF
Jenabian (2015)DR46DR46KF735849NRTINNRTIL74I, M184V, K219EK103N, V108I, P225HP4HQ, P9PS, K20R, V35T, T39L, D123E, E138G, S162C, K173A, Q174K, D177E, I178M, Q182K, T200A, Q207A, R211K, H221HY, P243A, V245Q, E248D, A272P, K275R, Q278N, T286A, E291D, I293V, E297A, L303M, Q334NF