<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation H221Y
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 13
Isolates 13
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Apetrei (2003)AC_Pat37RO.01.IS.37AY333540AZT, 3TC, D4TNVPK70RY181CV35T, T39A, E40A, K46Q, K49R, D123E, I135L, S162H, K173A, Q174K, P176Q, D177E, I195L, T200A, Q207T, R211K, H221YF
Rodrigues (2005)BLF_Pat3BR02SP249AY643219AZT, DDI, Unknown, 3TCNVP, UnknownM41L, M184V, L210W, T215YV108I, Y181CL34I, V35T, K49R, I135V, S162C, E169D, K173A, Q174K, T200I, Q207E, R211K, H221Y, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, K311RF
 BLF_Pat4BR02SP265AY643222D4T, DDI, 3TCNVPA62AV, K70NS, V75I, F77L, F116Y, Q151M, M184VK103N, Y181CE6S, K20R, V21VI, V35T, T39A, K64R, S68G, K122E, S162SC, E169D, K173A, Q174K, I178L, G196E, T200A, Q207E, R211K, H221Y, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297V, V317AF
 BLF_Pat36BR02SP117AY6432083TC, D4TEFV, NVPM41L, D67N, L74IV, M184V, T215YK103N, Y181C, G190AK20R, V35I, T39K, K43E, K49R, V118I, I142V, S162D, E169D, K173A, Q174K, G196E, T200A, E203D, Q207K, H208Y, R211A, H221Y, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297T, I329LF
Baxter (2006)48-90949094-30827DQ880717NRTINNRTIM41L, D67DN, L74I, M184V, L210W, T215Y, K219NV108VI, V179D, Y181C, F227LE44D, K103R, V106VI, V111I, K122A, I135T, S162C, M164ML, R172RK, K173A, Q174K, D177EG, I178L, E203D, Q207D, R211K, H221Y, V245QF
 48-91499149-30826DQ880762NRTINNRTIM41L, D67G, T69D, V75A, M184V, T215Y, K219RV108IT39A, E44Y, K49R, V111I, S117A, K122E, I135V, S162Y, S163T, E169D, K173T, Q174K, T200A, E203D, Q207E, H208Y, R211K, W212C, H221Y, K223Q, L228R, M230I, E233V, W239CF
 48-91519151-30826DQ880764NRTINNRTIM41L, L74LI, M184V, L210W, T215YK101KE, V108I, Y181C, G190GAE44D, K49R, V118I, K122E, I135V, S162C, E169A, K173A, Q174K, E203K, Q207E, R211K, H221Y, L228R, V245PF
Waleria-Aleixo (2008)08PR04017608PR040176FJ591207NRTINNRTIM41L, D67N, T69D, L210W, T215Y, K219NL100I, K103NK22R, V35T, T39L, K43E, E44A, D123E, I135L, S162C, K173T, Q174K, I178L, V179I, T200A, E203D, Q207E, R211K, H221Y, E224D, L228R, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E297A, A304E, V317A, Q334PF
Dumans (2009)RENA409RENA409FJ405119AZT, 3TC, D4T, DDIEFVD67N, K70R, K219QK103N, V108IE28K, K32E, V35M, T107S, D123E, S163C, E169D, K173A, Q174K, D177E, Q207E, R211K, H221Y, I244V, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E297PF
Jones (2012)165415165415JN670100NRTINNRTIM41L, D67N, K70KR, V75M, M184I, L210W, T215Y, K219NK103N, F227L, M230L, L234I, Y318FV35T, T39I, E44D, V60I, V106I, T107S, L109I, V118I, I142IV, S162Y, E169A, K173E, Q174R, T200A, E203D, Q207K, H208Y, R211E, H221Y, K223Q, L228H, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297A, S322T, I329V, R356K, G359N, A371V, I375V, T377V, K390R, Q394L, E399D, A400TF
Theys (2013)1905619056KC219961NRTI, TDFNNRTIK65RV108VI, Y181CE40D, K101R, D123E, I135V, I142IV, S162C, E169D, K173A, Q174K, D177E, T200A, Q207E, R211K, H221YF
 621621KC219069NRTI, TDFNNRTIT215FA98G, K103N, Y188HD121Y, K122E, D123E, I135T, T165I, K173T, Q174K, E194D, T200A, I202V, R211K, H221YF
 2236922369KC220133NRTI, TDFNNRTIM41L, D67DA, K70KR, M184V, T215TFIS, K219KEV108I, Y181CD123E, I135V, K173I, Q174K, V179I, Q207E, R211A, F214L, H221YF