<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation G190A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 27
Isolates 27
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patBAR01_BAR714AJ577734AZT, DDI, 3TC, D4T, ABCNVP, EFVT215FK103N, Y181C, G190AV35T, K49R, I135L, S162C, E169D, K173A, Q174K, Q207E, R211K, L228RF
Rodrigues (2005)BLF_Pat8BR03SP01AY643229AZT, 3TC, UnknownUnknown, NVPM41L, D67N, K70R, L74I, M184V, T215YA98G, K101E, G190AS3C, E6D, K20R, V35T, E44D, K49R, I135V, E138A, S162C, E169D, K173A, Q174K, I178L, T200E, E203K, Q207E, H208Y, R211K, K223E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, V317AF
 BLF_Pat24BR02SP255AY643220AZT, DDI, 3TC, D4TNVPM41L, D67N, L74V, M184V, L210W, T215YK101E, Y181C, G190AV35T, T39PS, K43N, E44D, V118I, K122E, I135V, S162Y, K173T, Q174K, N175Y, T200A, E203K, Q207D, R211K, K223Q, V245Q, E248D, T286A, A288T, V292I, I293V, E297A, Q334EF
 BLF_Pat33BR03SP36AY643247AZT, 3TC, DDI, D4TNVP, EFVD67N, K70R, M184V, T215F, K219EK101E, V108I, Y181C, G190AE6D, K20R, V35T, T39L, V60I, V90I, I135R, S162H, E169D, K173A, Q174K, V179I, T200R, Q207E, R211K, L228H, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297AF
 BLF_Pat36BR02SP117AY6432083TC, D4TEFV, NVPM41L, D67N, L74IV, M184V, T215YK103N, Y181C, G190AK20R, V35I, T39K, K43E, K49R, V118I, I142V, S162D, E169D, K173A, Q174K, G196E, T200A, E203D, Q207K, H208Y, R211A, H221Y, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297T, I329LF
Baxter (2006)48-30433043-30305DQ877955NRTINNRTIM41L, D67N, L74V, M184MV, L210W, T215Y, K219RK101E, V106M, G190A, F227LK20R, V35T, T39A, E44ED, W88S, V118I, K122E, D123DN, I135L, E138A, S162SG, E169D, K173A, Q174K, Q197K, T200A, E203K, Q207D, H208Y, R211K, K223E, V245Q, E248D, A272P, T286A, A288S, E291D, V292I, I293V, E297V, V314X, Q334QE, Q340QH, F346Y, R356K, G359S, I375V, A376S, T377IL, T386I, K390R, Q394L, E399D, A400TF
 48-32663266-30729DQ878171NRTINNRTID67N, K70R, L74I, M184V, T215F, K219QA98G, K103S, Y181C, G190AP4S, K20KR, V35T, T69N, K122E, D123E, I135L, E138EQ, T165I, I167V, E169EQ, K173A, Q174K, D177E, I178L, V179T, T200A, I202V, E204A, Q207E, R211K, D218E, P243T, V245Q, E248D, D250S, A272P, K275R, T286A, E291D, I293V, E297A, L303M, D324DE, I329V, F346H, R356RK, M357R, G359S, K366R, A371V, S379G, T386I, K390R, E399D, A400TF
 48-61786178-30731DQ878750NRTINNRTIM41L, D67N, T69D, L74IV, M184V, T215YA98G, V108VIM, Y181C, G190AS3C, K20R, V35T, E44D, K101KQ, D123E, I135V, S162C, I167IV, E169D, R172RK, K173A, Q174K, I178L, Q207E, R211K, D218E, H221HY, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297A, E328D, R356K, G359S, T377L, K390R, Q394L, E399D, A400TF
Waleria-Aleixo (2008)08PR06071708PR060717FJ591539NRTINNRTIM41L, T215YA98G, G190AV10VA, V35T, K49R, K101Q, S162C, E169D, K173A, Q174K, G196E, Q207K, R211A, L228R, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297T, E328DF
 08PR06065408PR060654FJ591509NRTINNRTIM41L, M184V, L210W, T215YK101N, V108I, Y181C, G190AV35R, K49R, V106I, V118I, D123E, I135V, S162C, E169D, K173A, Q174K, I178L, T200A, Q207D, R211K, L228R, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E297A, K311RF
 08RJ04010908RJ040109FJ591593NRTINNRTIM41L, M184V, T215FA98G, Y181C, G190AV35T, I135V, S162C, K173T, Q174K, T200A, Q207D, R211K, L228H, V245Q, E248D, A272P, E291D, I293V, E297T, V317A, S322T, D324E, Q334LF
 08PR04020708PR040207FJ591237NRTINNRTIM41L, D67N, L74I, M184V, L210W, T215YK103NS, G190AV35K, T39TA, K43KE, E44A, K49R, D123E, I135T, S162C, E169D, K173A, Q174K, T200A, E203ED, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297T, E308QF
 08PR06070708PR060707FJ591530NRTINNRTIM184VK103N, G190AV35T, I135V, T139M, S162C, E169D, K173A, Q174E, Q197K, T200E, E203D, E204K, Q207E, V245Q, E248DF
 08RJ06048808RJ060488FJ591681NRTINNRTIF77FL, M184V, T215Y, K219KEQK101E, G190A, F227LE6K, E28K, V35T, T39A, K49R, K104R, V106I, K122E, I135V, S162C, E169D, K173A, Q174K, D177E, I178L, V179I, T200A, I202IV, E203V, Q207E, R211K, K223E, L228R, V245H, E248D, A272P, V276I, L283I, T286A, E291D, V292I, I293V, E297T, V317A, D324EF
 08PR06065608PR060656FJ591511NRTINNRTIM41L, D67N, T69D, K70R, T215F, K219QK101E, V108I, Y181C, G190AK20R, V35T, T39K, K43L, V60I, L109V, D123E, I135L, I142V, S162Y, E169A, R172K, K173A, Q174K, D177E, T200K, E203K, Q207E, D218E, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, I326M, E328D, I329VF
 08RJ05046108RJ050461FJ591655NRTINNRTIM184VK103S, G190AV35T, K49R, V60I, D123E, I135V, E169D, K173T, Q174K, I178L, T200A, Q207N, R211K, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E297A, Q334DF
 08PR05045408PR050454FJ591451NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215YK103N, G190AE28K, K32E, V35T, T39DE, K49X, V60I, V118I, K122E, D123E, I135T, S162C, E169A, K173A, Q174K, N175Y, T200A, E203A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297T, I329LF
 08PR06066808PR060668FJ591523NRTINNRTIM41L, T215YK101E, G190AV35T, T39L, K43R, S68G, V118I, D123E, E138Q, S162C, E169D, P170S, K173AT, Q174K, D177E, V245Q, E248N, V261I, A272P, T286A, E291D, V292I, I293V, E297A, Q334QPF
 08RJ05046408RJ050464FJ591658NRTINNRTIM41L, A62V, V75T, M184V, L210W, T215Y, K219NK101H, V108I, Y181C, G190AE28K, K32E, V35T, T39N, E44D, K49R, K64R, V118I, D123E, I135V, S162C, K173T, Q174K, I178L, V189I, E203K, Q207E, H208Y, R211K, K223Q, L228R, V245Q, A272P, T286A, E291D, V292I, I293V, E297TF
Dumans (2009)RENA244RENA244FJ405174AZT, DDI, D4T, 3TC, UnknownNVP, EFV, UnknownM41L, D67N, T69D, K70R, V75M, T215F, K219QK103N, G190AE6D, V35T, V60I, V90I, K102N, S117A, D121H, K122E, I135T, S162Y, E169D, P170L, F171Y, Q174K, D177E, G196E, T200A, E203D, Q207E, L228H, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317AF
Fokam (2011)CIRCB-11096CIRCB-11096JQ796179D4T, 3TCNVPD67DN, M184V, T215FK101E, Y181C, G190AK20R, V35T, T39D, K122E, D123E, E138Q, I142V, E169ED, K173A, Q174K, D177E, I178IL, Q207E, V241VI, P243A, V245Q, E248D, K249KE, A272P, K275R, Q278H, T286A, E291D, I293V, P294T, E297A, L303LM, Q334H, G335D, F346HF
Afonso (2012)ANG11ANG11JN937026NRTINNRTIM184VK101E, G190AV21I, V35T, D123N, I135V, E138A, S162C, Q174K, D177E, T200A, Q207D, R211K, P243S, V245H, E248DF
Jones (2012)187729187729JN670739NRTINNRTIL74V, Y115F, M184V, T215YK103S, V179VD, Y181YC, G190AV21I, V35T, T39E, V60I, S68SG, K122E, I135T, K173AT, Q174K, N175Y, D177E, Q197E, T200K, Q207E, R211K, H221HY, V245Q, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, E297K, Q334H, G335D, R356K, G359S, A371V, I375V, T377Q, K390R, E399D, A400TF
Kouri (2012)CU484-10CU484-10JQ585397NRTINNRTID67N, K70R, M184V, K219QK103N, G190AV21VI, V35T, T39A, E40D, V60I, K122P, D123E, I135T, I142V, Q174AE, D177EG, T200A, R206K, Q207E, L228H, V245Q, A272P, K275R, V276I, L283I, A288T, V292I, I293V, E297A, L301M, E312EA, D324E, Q334DF
 CU599-10CU599-10JQ585404NRTINNRTIM41L, D67S, T69S_RG, K70R, F77FL, M184V, T215F, K219EA98G, K101E, V108I, Y181C, G190AE28K, K32E, V35T, V60I, S68G, V106I, L109V, V118I, K122P, D123E, I135V, I159L, D177E, I180IM, Q207E, R211K, F214L, D218E, L228H, V245Q, A272P, V276T, K277R, L283I, T286A, A288T, V292I, I293V, E297AF
Pircher (2013)B1152B1152JX110248D4T, 3TC, AZTNVPM41L, D67N, K70R, V75VL, M184V, T215F, K219QA98G, K101E, G190AE6D, K11Q, E28K, K32E, V35T, T39M, K43N, V60I, T69S, K122E, D123N, F171Y, K173T, Q174K, D177E, I178M, V179VI, R211K, L228Q, V245Q, E248N, D250EF
Theys (2013)1872218722KC219944NRTI, TDFNNRTIM41L, T69D, L210W, T215YK101E, Y181C, G190AK43M, V118I, K122E, I135V, S162C, E169D, K173T, Q174K, L228RF