<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Dumans (2004)RES40RES40AY390200AZT, DDI, D4T, 3TC, UnknownEFV, UnknownD67N, K219QK101KE, K103N, K238TI135V, E138A, S162C, E169D, K173T, Q174K, D185X, D186DN, T200A, I202V, Q207E, F214L, V245QF
Rodrigues (2005)BLF_Pat8BR03SP01AY643229AZT, 3TC, UnknownUnknown, NVPM41L, D67N, K70R, L74I, M184V, T215YA98G, K101E, G190AS3C, E6D, K20R, V35T, E44D, K49R, I135V, E138A, S162C, E169D, K173A, Q174K, I178L, T200E, E203K, Q207E, H208Y, R211K, K223E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, V317AF
Baxter (2006)48-30433043-30305DQ877955NRTINNRTIM41L, D67N, L74V, M184MV, L210W, T215Y, K219RK101E, V106M, G190A, F227LK20R, V35T, T39A, E44ED, W88S, V118I, K122E, D123DN, I135L, E138A, S162SG, E169D, K173A, Q174K, Q197K, T200A, E203K, Q207D, H208Y, R211K, K223E, V245Q, E248D, A272P, T286A, A288S, E291D, V292I, I293V, E297V, V314X, Q334QE, Q340QH, F346Y, R356K, G359S, I375V, A376S, T377IL, T386I, K390R, Q394L, E399D, A400TF
Dumans (2009)RENA181RENA181FJ405173AZT, DDI, 3TC, D4TEFVM41ML, T215YL100LI, K101E, K103NK20R, V35T, K49R, V106I, K122E, I135V, E138A, S162C, E169D, Q174K, D177Q, I178L, V179I, Q207D, R211K, L228LR, V245Q, E248D, A272P, K277R, T286A, A288T, E291D, V292I, I293V, E297A, V317AF
Afonso (2012)ANG11ANG11JN937026NRTINNRTIM184VK101E, G190AV21I, V35T, D123N, I135V, E138A, S162C, Q174K, D177E, T200A, Q207D, R211K, P243S, V245H, E248DF
Alcantara (2013)BRGO4188BRGO4188JN114227NRTINNRTIM184V K20R, V35I, S48T, A98S, I135L, E138A, E194EQ, T200TA, Q207E, R211KF
 BRGO4063BRGO4063JN114157NRTINNRTI  K20R, V35T, K49R, V60I, K122E, E138A, S162C, E169D, F171Y, K173A, Q174K, T200I, Q207A, R211KF
Theys (2013)52585258KC219404NRTI, TDFNNRTIK70KE, M184VL100LI, K103N, P225PHA98S, K122E, D123E, I135L, E138A, S162C, R172RK, K173N, Q174K, V179VI, T200E, I202V, E203EK, Q207E, R211KF
Aghokeng (2014)CM-2-113CM-2-113KC350190NRTINNRTID67DNK101KE, V106M, V179VDV35T, T39K, E40D, K122R, D123E, E138A, S162A, K173A, Q174K, I202V, E203EK, Q207E, F214L, P243A, V245Q, E248D, D250S, A272P, K275R, Q278H, K281R, T286A, E291D, I293V, E297A, L303M, Q334H, G335DF