<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation K101E
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 18
Isolates 18
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)UK2205UK2205AY901813AZT, 3TCNVPM184VK101E, G190SP4S, E6D, V35T, T39E, K104R, D123DE, F171Y, K173T, Q174K, T200A, Q207E, F214FLF
Rodrigues (2005)BLF_Pat8BR03SP01AY643229AZT, 3TC, UnknownUnknown, NVPM41L, D67N, K70R, L74I, M184V, T215YA98G, K101E, G190AS3C, E6D, K20R, V35T, E44D, K49R, I135V, E138A, S162C, E169D, K173A, Q174K, I178L, T200E, E203K, Q207E, H208Y, R211K, K223E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, V317AF
 BLF_Pat22BR03SP87AY643251AZT, 3TC, D4T, DDINVPM41L, M184V, L210W, T215YK101E, Y181CG, G190GAE6N, K20R, V35T, T39K, K43E, E44D, V118I, K122E, I135V, S162Y, K173A, Q174K, V179VI, Q207E, R211K, L228H, Q242X, V245Q, A272P, K275Q, V276T, T286A, A288T, E291D, V292I, I293V, P294S, E297TF
 BLF_Pat24BR02SP255AY643220AZT, DDI, 3TC, D4TNVPM41L, D67N, L74V, M184V, L210W, T215YK101E, Y181C, G190AV35T, T39PS, K43N, E44D, V118I, K122E, I135V, S162Y, K173T, Q174K, N175Y, T200A, E203K, Q207D, R211K, K223Q, V245Q, E248D, T286A, A288T, V292I, I293V, E297A, Q334EF
 BLF_Pat29BR03SP247AY643244AZT, DDI, Unknown, 3TC, D4TUnknown, NVPM41L, D67N, T215YK101E, Y181IE6K, V35MR, T39A, K122E, S162D, F171Y, K173T, Q174K, E203K, Q207E, R211K, K223Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297A, V317A, G333E, Q334YF
 BLF_Pat33BR03SP36AY643247AZT, 3TC, DDI, D4TNVP, EFVD67N, K70R, M184V, T215F, K219EK101E, V108I, Y181C, G190AE6D, K20R, V35T, T39L, V60I, V90I, I135R, S162H, E169D, K173A, Q174K, V179I, T200R, Q207E, R211K, L228H, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297AF
Baxter (2006)48-30433043-30305DQ877955NRTINNRTIM41L, D67N, L74V, M184MV, L210W, T215Y, K219RK101E, V106M, G190A, F227LK20R, V35T, T39A, E44ED, W88S, V118I, K122E, D123DN, I135L, E138A, S162SG, E169D, K173A, Q174K, Q197K, T200A, E203K, Q207D, H208Y, R211K, K223E, V245Q, E248D, A272P, T286A, A288S, E291D, V292I, I293V, E297V, V314X, Q334QE, Q340QH, F346Y, R356K, G359S, I375V, A376S, T377IL, T386I, K390R, Q394L, E399D, A400TF
 48-42864286-30910DQ878509NRTINNRTIM41L, D67N, T69~, L74V, Y115F, F116Y, Q151M, M184V, L210W, T215Y, K219EK101E, V108I, Y181C, G190SV35T, T39A, S48E, V60I, S68G, D123E, R172K, K173A, Q174K, D177E, I178M, G196GE, T200A, Q207A, R211K, H221HY, L228H, P243A, V245Q, E248D, D250S, A272P, K275R, Q278N, T286A, E291D, I293V, E297A, R307RK, D324E, Q334H, G335D, F346H, R356K, M357K, G359S, A371V, I375V, T386I, K390R, A400TF
 48-92899289-30930DQ880879NRTINNRTID67N, K70R, T215F, K219QK101E, Y181C, G190ST39L, K49R, V60I, T69TN, S162H, E169D, K173T, Q174K, G196E, Q207E, L228H, V245QF
Waleria-Aleixo (2008)08RJ06047008RJ060470FJ591664NRTINNRTID67N, K70R, M184V, T215F, K219QK101E, K103NK20R, E28K, V35T, T39A, K49R, I94L, I135T, S162C, E169A, K173A, Q174R, I178M, T200A, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, R307KF
 08RJ06048808RJ060488FJ591681NRTINNRTIF77FL, M184V, T215Y, K219KEQK101E, G190A, F227LE6K, E28K, V35T, T39A, K49R, K104R, V106I, K122E, I135V, S162C, E169D, K173A, Q174K, D177E, I178L, V179I, T200A, I202IV, E203V, Q207E, R211K, K223E, L228R, V245H, E248D, A272P, V276I, L283I, T286A, E291D, V292I, I293V, E297T, V317A, D324EF
 08PR06065608PR060656FJ591511NRTINNRTIM41L, D67N, T69D, K70R, T215F, K219QK101E, V108I, Y181C, G190AK20R, V35T, T39K, K43L, V60I, L109V, D123E, I135L, I142V, S162Y, E169A, R172K, K173A, Q174K, D177E, T200K, E203K, Q207E, D218E, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, I326M, E328D, I329VF
 08PR06066808PR060668FJ591523NRTINNRTIM41L, T215YK101E, G190AV35T, T39L, K43R, S68G, V118I, D123E, E138Q, S162C, E169D, P170S, K173AT, Q174K, D177E, V245Q, E248N, V261I, A272P, T286A, E291D, V292I, I293V, E297A, Q334QPF
Dumans (2009)RENA181RENA181FJ405173AZT, DDI, 3TC, D4TEFVM41ML, T215YL100LI, K101E, K103NK20R, V35T, K49R, V106I, K122E, I135V, E138A, S162C, E169D, Q174K, D177Q, I178L, V179I, Q207D, R211K, L228LR, V245Q, E248D, A272P, K277R, T286A, A288T, E291D, V292I, I293V, E297A, V317AF
Fokam (2011)CIRCB-11096CIRCB-11096JQ796179D4T, 3TCNVPD67DN, M184V, T215FK101E, Y181C, G190AK20R, V35T, T39D, K122E, D123E, E138Q, I142V, E169ED, K173A, Q174K, D177E, I178IL, Q207E, V241VI, P243A, V245Q, E248D, K249KE, A272P, K275R, Q278H, T286A, E291D, I293V, P294T, E297A, L303LM, Q334H, G335D, F346HF
Afonso (2012)ANG11ANG11JN937026NRTINNRTIM184VK101E, G190AV21I, V35T, D123N, I135V, E138A, S162C, Q174K, D177E, T200A, Q207D, R211K, P243S, V245H, E248DF
Kouri (2012)CU544-09CU544-09JQ585255NRTINNRTIM41L, L74V, M184V, T215YK101E, Y181C, G190GEV35M, T39K, K43E, D123E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272S, T286A, E291D, V292I, I293V, E297A, V317A, I326VF
Theys (2013)1872218722KC219944NRTI, TDFNNRTIM41L, T69D, L210W, T215YK101E, Y181C, G190AK43M, V118I, K122E, I135V, S162C, E169D, K173T, Q174K, L228RF