<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 15
Isolates 15
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL29021102123 AZT, 3TC, D4T, DDIEFVM41L, L74V, T215YL100I, K103NV35KR, K43KQ, K102R, D123E, S162SC, E169D, R172RK, K173A, Q174K, E203EK, Q207E, R211K, K223Q, L228R, V245Q, E248D, A272P, T286A, V292I, I293V, E297AVF
Rodrigues (2005)BLF_Pat38BR03SP211AY643240AZT, DDI, 3TC, D4TNVPM41L, L74V, M184V, T215FL100I, K103NK20R, V35T, T39S, K122E, E169D, K173A, Q174K, D177DG, T200A, E203K, Q207E, H208Y, R211K, K223E, L228R, V245Q, E248D, A272P, E291D, V292I, I293V, E297A, I326V, I329VF
 BLF_Pat42BR02SP154AY643211AZT, DDI, 3TC, UnknownEFV, UnknownL74V, T215DL100I, K103NV35T, E169D, K173T, Q174K, T200A, Q207D, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E297AF
Baxter (2006)48-92729272-30922DQ880864NRTINNRTIM41L, V75M, M184V, L210W, T215Y, K219NL100I, K103NT39A, K43E, E44A, K102R, V118VI, D123DE, I135V, K173T, Q174K, D177G, G196E, T200A, E203AV, Q207E, H208Y, R211K, H221HY, L228HR, Q242QH, V245QF
 48-90259025-30825DQ880664NRTINNRTIM41L, D67N, K70R, L74V, T215Y, K219EL100I, K103NT39K, K43E, E44A, K49R, D123E, S162C, E169D, P170PS, K173A, Q174K, D177DN, I178L, Q207A, H208Y, R211K, W212WL, D218E, L228H, V245QF
 48-92509250-30908DQ880845NRTINNRTID67N, K70R, L74IV, V75VAIT, M184V, T215F, K219EL100I, K103NT69N, K122E, I135V, E169D, P170L, K173A, Q174K, D177N, G196E, Q207E, R211K, L228H, V245QF
Waleria-Aleixo (2008)08PR04017608PR040176FJ591207NRTINNRTIM41L, D67N, T69D, L210W, T215Y, K219NL100I, K103NK22R, V35T, T39L, K43E, E44A, D123E, I135L, S162C, K173T, Q174K, I178L, V179I, T200A, E203D, Q207E, R211K, H221Y, E224D, L228R, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E297A, A304E, V317A, Q334PF
 08PR05024108PR050241FJ591270NRTINNRTIM41L, L74V, M184V, L210W, T215YL100I, K103NT7P, L34I, V35T, T39R, K43E, V118I, S162Y, K173T, Q174K, N175Y, G196E, T200A, E203K, Q207E, H208Y, R211K, K223Q, L228R, V241L, V245K, A272S, T286A, E291D, V292I, I293V, E297V, I329VF
 08RJ06056808RJ060568FJ591728NRTINNRTIM41L, D67N, K70R, V75M, T215F, K219QL100I, K103NV21I, K32KI, V35R, T39S, K43KQ, K49R, V60I, K122KE, I135V, S162C, E169A, K173E, Q174K, N175Y, T200A, Q207D, R211K, D218E, L228HR, V245Q, E248D, T286A, V292I, I293V, E297A, Q334EF
 08RJ06057808RJ060578FJ591738NRTINNRTIM41L, L74V, V75VL, M184V, T215YL100I, K103NV35T, T39D, K102HQ, D121HY, K122E, I135T, S162C, K173A, Q174K, D177E, I178L, T200K, Q207D, R211K, K223KQ, L228LR, V245Q, E248D, A272P, T286A, V292VI, I293V, E297K, S322TF
 RES314RES314FJ592003NRTINNRTIM41L, K70KE, L74V, M184V, T215FL100I, K103NT7TI, V35K, T39A, V118I, I135T, S162Y, E169D, K173A, Q174R, G196E, Q207E, R211K, F214L, L228LR, V245Q, E248D, K263EF
Dumans (2009)RENA654RENA654FJ405122AZT, DDI, 3TC, D4TEFVM41L, T215FL100I, K103NV35T, K43N, I135V, E169D, K173A, Q174K, I178L, G196E, Q207A, R211K, L228R, P243S, A272P, K277R, T286A, E291D, V292I, I293V, E297AF
 RENA502RENA502FJ405148DDC, AZT, 3TC, D4T, DDIEFVD67N, K70S, L74V, M184V, T215YL100I, K103NE6D, K20R, V35M, K49R, P97PS, K122E, D123E, A129AV, I135T, P150PS, E169A, K173A, Q174K, I178L, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, V317AF
Charpentier (2010)T128002T128002HQ717814NRTINNRTI, ETRM41L, L74V, V75S, M184V, T215Y, K219KNL100I, V179DT39A, K43E, K73M, K103R, K122AE, D123T, I135T, S162C, E169D, Q174K, D177E, Q207E, R211K, H221HYF
Rhee (2017)68046804_FL TDF, FTCEFVK65R, Y115F, M184VL100I, K103NE28K, V35T, T39A, E40D, K49R, K122P, D123E, I135T, S162C, E169D, K173A, Q174K, D177E, I178L, V179I, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E297A, S322A, Q334CF