<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 4
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL29021102123 AZT, 3TC, D4T, DDIEFVM41L, L74V, T215YL100I, K103NV35KR, K43KQ, K102R, D123E, S162SC, E169D, R172RK, K173A, Q174K, E203EK, Q207E, R211K, K223Q, L228R, V245Q, E248D, A272P, T286A, V292I, I293V, E297AVF
Rodrigues (2005)BLF_Pat38BR03SP211AY643240AZT, DDI, 3TC, D4TNVPM41L, L74V, M184V, T215FL100I, K103NK20R, V35T, T39S, K122E, E169D, K173A, Q174K, D177DG, T200A, E203K, Q207E, H208Y, R211K, K223E, L228R, V245Q, E248D, A272P, E291D, V292I, I293V, E297A, I326V, I329VF
 BLF_Pat42BR02SP154AY643211AZT, DDI, 3TC, UnknownEFV, UnknownL74V, T215DL100I, K103NV35T, E169D, K173T, Q174K, T200A, Q207D, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E297AF
Baxter (2006)48-92729272-30922DQ880864NRTINNRTIM41L, V75M, M184V, L210W, T215Y, K219NL100I, K103NT39A, K43E, E44A, K102R, V118VI, D123DE, I135V, K173T, Q174K, D177G, G196E, T200A, E203AV, Q207E, H208Y, R211K, H221HY, L228HR, Q242QH, V245QF
 48-90259025-30825DQ880664NRTINNRTIM41L, D67N, K70R, L74V, T215Y, K219EL100I, K103NT39K, K43E, E44A, K49R, D123E, S162C, E169D, P170PS, K173A, Q174K, D177DN, I178L, Q207A, H208Y, R211K, W212WL, D218E, L228H, V245QF
 48-92509250-30908DQ880845NRTINNRTID67N, K70R, L74IV, V75VAIT, M184V, T215F, K219EL100I, K103NT69N, K122E, I135V, E169D, P170L, K173A, Q174K, D177N, G196E, Q207E, R211K, L228H, V245QF
Dumans (2009)RENA654RENA654FJ405122AZT, DDI, 3TC, D4TEFVM41L, T215FL100I, K103NV35T, K43N, I135V, E169D, K173A, Q174K, I178L, G196E, Q207A, R211K, L228R, P243S, A272P, K277R, T286A, E291D, V292I, I293V, E297AF
 RENA502RENA502FJ405148DDC, AZT, 3TC, D4T, DDIEFVD67N, K70S, L74V, M184V, T215YL100I, K103NE6D, K20R, V35M, K49R, P97PS, K122E, D123E, A129AV, I135T, P150PS, E169A, K173A, Q174K, I178L, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, V317AF