<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation A98S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2006)48-41654165-30410DQ878398NRTINNRTIM41L, D67N, K70R, T215F, K219QK101E, G190SV35T, K49R, V60I, T69TN, V90I, A98S, V118I, K122E, I135T, E138A, T165I, E169D, R172RK, D177E, I178L, V179X, Q197E, E203A, Q207E, R211K, F214L, L228H, V245T, D250E, A272P, K277R, T286A, E297KR, I329L, G335D, M357MT, G359S, A376T, S379C, T386A, A400TD
Sigaloff (2011)HIV101849HIV101849JN132282AZT, 3TCNVPM41L, D67N, K70R, M184V, T215F, K219QK101E, G190A, K238NV35T, V60I, A98S, K122E, D123N, I135V, E138A, I142T, S162C, D177E, I178M, V179I, T200R, Q207E, R211K, L228H, V245E, D250E, A272P, K277R, L282C, L283I, T286A, I293V, E297AD
Kouri (2012)CU194-11CU194-11JQ585494NRTINNRTIM41L, L210RW, T215S, K219KNY181YC, G190AV8I, V35T, T39A, K43N, E44D, V60I, S68G, A98S, V111VI, K122E, I135AT, E169D, K173KE, D177E, V179IS, G196GE, T200A, E203D, Q207E, D237E, V245T, A272S, T286V, I293V, E297K, P313Q, Y319YN, I329V, G335ED
Sigaloff (2013)JCR111_0JCR111_0JX182003NRTINNRTIM184V, T215FK101E, G190AE28R, V35T, K49R, V60I, A98S, K122E, I135T, I142V, D177E, V179I, Q207E, R211K, V245Q, D250E, K277R, L282C, E297AD
 JCR093_0JCR093_0JX181998NRTINNRTIM184V, T215YK103NV35T, T39K, S48T, K49R, V60I, A98S, D121Y, K122E, I135T, D177E, I178M, T200A, Q207E, R211K, V245K, E248D, A272P, K277R, K281R, L282C, T286A, I293V, I309LD
Neogi (2014)5086050860 TDF, FTCEFV  E6*, K11T, V35T, A98S, D121H, I142V, D177E, I178M, T200M, Q207E, R211K, V245K, K249R, D250E, I257L, S268C, A272P, K277R, L282C, T286A, I293V, P294A, I329IVD
Brooks (2016)2102A2102AKU900896TDF, 3TCEFVK70E, M184VY181CV35T, K49R, V60I, A98S, K122E, D123S, I135T, D177E, I178M, E203EK, Q207E, R211K, L228LRD
Kityo (2017)8353383533KY062087NRTINNRTIK70E, V75M, M184V, T215IY188C, M230LV60I, A98S, V106I, V118I, D121H, K122E, R125K, I135T, I142V, D177E, T200L, Q207E, R211K, F214L, E224D, L228RD
 8300283002KY061564NRTINNRTID67N, K70R, M184V, K219KHNQK101E, K238TK43E, K49R, P52PL, V60I, I94L, P97PL, A98S, D121H, K122E, I135T, E169D, D177E, I178M, T200R, E203K, Q207ED
Svard (2017)2nd_20332nd_2033KX7752783TC, D4T, TDF, FTCNVPM184V, L210W, T215Y, K219KQK101E, G190AE28R, K32E, V35T, K49R, V60I, A98S, D121Y, K122E, D123E, S162D, E169D, D177E, I178IM, V179I, T200K, Q207E, R211K, P243S, V245K, D250ED