<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation A98G
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2006)48-14391439-30929DQ877829NRTINNRTIM41L, L74V, L210W, T215YA98G, L100I, K103NV35T, T39K, K43E, E44D, K49R, V60I, K122E, Q174K, D177E, I178M, Q207E, R211K, V245Q, D250E, A272P, L282C, L283I, R284K, T286S, I293V, E297A, G335D, P345Q, F346Y, K347KR, R356K, A360T, T377Q, S379C, K390R, A400TD
Aulicino (2011)ARN272RLDARN272RLDFJ525856NRTINNRTIM41L, D67N, T69D, K70R, L74V, M184V, L210W, T215Y, K219HA98G, K101E, V108I, Y181C, G190AS3C, K20R, E28A, V35T, T39E, E44D, V60I, V90I, L109I, K122E, I135V, I142V, S162N, I167V, V179I, T200A, E203K, Q207E, H208Y, R211KD
Charpentier (2011)CR-47CR-47FJ688253AZT, 3TCNNRTIM41L, L74I, M184V, L210W, T215YA98G, K103N, V108IK20R, V35I, T39A, E44D, V60I, V118I, K122E, I135IMT, I142T, D177E, I178L, E203EK, Q207E, H208HY, R211RK, K223KE, L228LH, V245T, D250E, A272P, K277R, T286A, V292ID
Kouri (2012)CU90-10CU90-10JQ585361NRTINNRTIM41ML, L74IV, M184V, T215FA98GV35T, K49R, V60I, K122E, I135L, E169D, D177E, Q197K, T200S, Q207E, H208Y, R211K, V245T, D250E, A272S, T286A, A288AG, E297A, I326T, I329VD
 CU311-10CU311-10JQ585381NRTINNRTIM41L, L74IV, M184V, T215FA98GV35T, K49R, V60I, K122E, I135L, E169D, D177E, Q197K, T200S, Q207E, H208Y, R211K, V245T, D250E, A272S, T286A, A288G, E297A, I326T, I329VD
Pircher (2013)B1117B1117JX110218D4T, 3TC, AZTNVPM41L, T69D, V75M, M184V, L210W, T215YA98G, Y181CI31L, V35IT, T39A, E44D, V60I, K101Q, V106I, V118I, P119PS, D121C, K122E, S162N, Q174K, D177E, I178V, T200E, K201M, E203K, E204Q, Q207A, R211K, K223T, L228R, V245TD
Sigaloff (2013)JCR047_0JCR047_0JX181988NRTINNRTID67G, T69D, K70R, M184V, K219HA98G, V108I, Y181CV35T, K43E, K49R, V60I, I94L, K122E, I135M, S163SC, T165L, R172K, D177E, I178M, T200I, E203R, E204K, Q207E, R211K, E224K, V245K, D250E, A272P, Q278H, L282C, L283I, T286A, A288TD
 JCR024_0JCR024_0JX181986NRTINNRTIM184VA98G, K103N, P225HV35T, E40D, K49R, V60I, D121H, K122E, I135T, S162A, N175H, D177E, I178M, T200M, K201I, Q207E, R211K, F214L, V245T, D250E, A272P, K277RD
 JCR113_0JCR113_0JX182004NRTINNRTIM41L, D67N, V75VL, M184V, L210W, T215YA98G, G190AE6N, K11Q, V35T, E44D, K49R, V60I, I94L, K101Q, V111IM, D121Y, K122E, I135M, T165I, D177E, Q207E, R211K, V245Q, L282C, L283I, K287R, I293VD
 JFP058_0JFP058_0JX182010NRTINNRTID67N, K70R, M184V, K219QA98G, K103N, P225HV35T, E40D, V60I, T69S, K122E, D123N, I135L, D177E, T200I, Q207E, R211K, L228H, V245K, D250E, A272S, L282C, L283I, T286A, I293VD
Meini (2015)111123111123KM438256AZT, 3TC, D4T, ABCNVP, EFVM41L, M184V, L210LW, T215YA98G, Y188LV35T, V60I, V106VI, D121H, K122E, I135IT, D177E, I178L, V179VI, T200I, Q207E, R211KD
 109258109258KM438243D4T, 3TC, DDINVPM41L, L74LI, M184V, L210W, T215FYA98G, G190AK20R, K32R, V35T, T39K, K43KE, V60I, S68SG, V118VI, D121C, K122E, I135ILM, S162SDGN, I178M, V179I, T200A, Q207E, R211K, V245ED