<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation K238T
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 16
Isolates 16
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK1014TK1014 AZT, DDI, 3TC, D4T, ABCEFVD67N, K70R, K219HK103N, K238TP14PS, V35T, T39A, K43KE, V60I, V118VG, D121Y, K122E, D123E, I142IV, A158AS, D177E, I178M, T200R, E203K, Q207E, R211K, V245R, D250E, A272P, K275R, Q278H, L282C, T286A, I293V, E297EKD
Baxter (2006)48-14321432-30818DQ877822NRTINNRTID67N, K70R, M184V, K219HK103N, K238TP14LS, V35T, T39A, K43E, V60I, F87FL, D121Y, K122E, D123E, D177E, I178M, T200R, E203K, Q207DE, R211K, V245R, D250E, A272P, K275R, Q278H, L282C, T286A, I293V, E297K, G335D, P345Q, F346Y, R356K, M357S, A360T, A371V, I375V, T377H, S379C, K390R, A400TD
Kouri (2012)CU1627-09CU1627-09JQ585302NRTINNRTID67N, K70R, L74I, M184V, T215F, K219QK103N, K238TV35T, E53D, V60I, D121Y, K122E, S162Y, D177E, I178M, T200A, E203D, E204AT, Q207E, H208Y, R211K, L228H, V245T, D250E, A272S, K277R, T286A, E297K, P313S, V317A, I329V, G333ED
 CU461-09CU461-09JQ585253NRTINNRTIM41L, D67DE, L74LV, M184V, L210W, T215YK103N, K238TV35T, E36K, T39A, K43KE, K49R, V60I, S68G, V118I, D121Y, K122E, S162DN, E169D, Q174R, D177E, I178M, T200A, E203EK, Q207E, H208HY, R211RK, K223KQ, V245T, E248D, A272P, T286A, P294A, E297EK, P313Q, I329V, G333E, G335GED
 CU1892-09CU1892-09JQ585315NRTINNRTIM41L, V75M, M184V, L210W, T215YK103N, K238TV35T, T39TA, E44D, V60I, V118I, K122E, D123N, I135T, I142T, S162N, D177E, T200A, Q207E, V245Q, D250G, A272P, T286A, I293VD
Sigaloff (2013)MBA036_0MBA036_0JX182014NRTINNRTIM184VK103N, P225H, K238TV35T, V60I, I142V, S162C, D177E, I178M, Q197E, T200K, Q207K, R211K, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, L283I, I293VD
 JCR077_0JCR077_0JX181994NRTINNRTIM41L, T69D, K70KR, M184V, L210W, T215FK101E, Y181C, K238TV35T, V60I, V118VI, D121Y, K122E, I135R, D177E, V179I, Q207E, R211K, L228R, V245K, D250E, I257L, A272P, K281R, L282C, T286A, E291A, I293VD
Hassan (2014)RS09000833RS09_833KC568496D4T, 3TCNVPM184VK103N, K238TV35T, K49R, V60I, I135T, D177E, I178V, T200I, Q207E, R211K, L228LR, V245E, D250E, A272P, V276I, Q278H, K281R, L282C, L283I, T286A, V292I, I293VD
Kekitiinwa (2017)65799_34965799_349KY237942NRTINNRTI K238TK49R, V60I, K64R, D123DN, S162A, D177E, T200I, Q207E, R211KD
Kityo (2017)8302183021KY061581NRTINNRTIM41L, D67DE, L74LI, V75VIM, M184V, L210W, T215YK103N, P225H, K238TE44D, V60I, S68SG, V118VI, D121Y, K122E, I135T, I142V, D177E, I178M, G196GE, T200AE, E203K, Q207E, R211K, K223E, L228RD
 8292882928KY061492NRTINNRTID67N, K70R, M184V, T215F, K219EK103N, V108I, K238TV60I, T69TN, K122E, D123N, E169D, D177E, I178M, T200M, E204K, Q207E, H208HY, R211K, D218ED
 8299982999KY061561NRTINNRTIM184VK103N, P225H, K238TV60I, K101KQ, D121Y, K122E, D177E, I178M, T200I, Q207G, R211KD
 8319883198KY061754NRTINNRTID67N, K70R, M184V, T215FI, K219QA98G, G190A, K238TK49R, V60I, D121H, K122E, I142IV, S162DN, D177E, I178M, V179VI, E194D, T200I, Q207E, R211K, F214FL, L228LHD
 8300283002KY061564NRTINNRTID67N, K70R, M184V, K219KHNQK101E, K238TK43E, K49R, P52PL, V60I, I94L, P97PL, A98S, D121H, K122E, I135T, E169D, D177E, I178M, T200R, E203K, Q207ED
 8290282902KY061467NRTINNRTIK70E, M184V, K219RK103N, P225H, K238TK49R, V60I, D121Y, K122E, D123G, D177E, I178M, T200IM, Q207GR, H208HL, R211K, L228RD
 8299882998KY061560NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215YA98G, K103N, K238TE44D, K49KR, V60I, D121Y, K122E, I142V, D177E, I178M, T200K, Q207E, R211KD