<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ndembi (2010)13025D_P113025GQ409547AZT, 3TCNVPD67G, M184VG190A, M230LV35T, T39K, S48T, I50V, V60I, E79V, K102Q, K122E, D177E, I178M, T200I, E203G, Q207E, R211KD
 14188D_P114188GQ409564AZT, 3TCNVPM184V, T215NG190A, M230LV21I, V35T, E44D, V60I, K122E, D123E, D177E, I178M, G196E, T200I, Q207G, R211KD
Charpentier (2011)69CP001805 D4T, 3TCNVPT69TADN, M184V, K219NL100I, M230LV35T, E40D, K49R, V60I, E203K, Q207E, R211K, F227FY, L228LR, V245Q, D250E, K277R, L282C, L283I, T286A, I293VD
Kaleebu (2015)MSK-0015UGA-MSK-0015-2012 TDF, FTCNVPA62V, K65R, M184IA98G, Y181C, M230LE6K, K11Q, V35I, K122E, D177E, I178M, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, Q278H, L282C, L283I, I293V, P294AD
Kityo (2017)8340983409KY061963NRTINNRTIL74V, M184V, L210W, T215YA98AG, V108I, G190A, M230LK43E, E44D, V60I, V118I, D121H, K122E, I142MV, D177E, I178M, V189VI, Q207E, R211K, L228HD
 8353383533KY062087NRTINNRTIK70E, V75M, M184V, T215IY188C, M230LV60I, A98S, V106I, V118I, D121H, K122E, R125K, I135T, I142V, D177E, T200L, Q207E, R211K, F214L, E224D, L228RD
 8323283232KY061787NRTINNRTIM41L, T69D, M184V, L210W, T215YK103N, V108I, M230L, L234IK43E, S48T, K49R, V60I, D177E, I195L, Q207E, R211K, H221Y, L228HD
 2836328363KY061374NRTINNRTIM41L, T69D, M184V, L210W, T215YK103N, V108I, M230L, L234IV35T, E36D, T39R, K43E, S48T, K49R, V60I, D177E, I195L, Q207E, R211K, H221Y, L228H, V245K, D250E, A272P, L282C, L283I, R284K, I293VD
Svard (2017)1st_921st_92KX7752663TC, D4TNVPD67G, T69D, K70R, M184V, T215F, K219QK101P, K103N, P225H, M230LK32R, V35T, E40D, V60I, K122E, D123N, D177E, T200X, Q207D, R211K, L228LH, K249RD