<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 11
Isolates 11
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ndembi (2010)13025D_P113025GQ409547AZT, 3TCNVPD67G, M184VG190A, M230LV35T, T39K, S48T, I50V, V60I, E79V, K102Q, K122E, D177E, I178M, T200I, E203G, Q207E, R211KD
 14188D_P114188GQ409564AZT, 3TCNVPM184V, T215NG190A, M230LV21I, V35T, E44D, V60I, K122E, D123E, D177E, I178M, G196E, T200I, Q207G, R211KD
Charpentier (2011)69CP001805 D4T, 3TCNVPT69TADN, M184V, K219NL100I, M230LV35T, E40D, K49R, V60I, E203K, Q207E, R211K, F227FY, L228LR, V245Q, D250E, K277R, L282C, L283I, T286A, I293VD
Reynolds (2012)B0708B0708-1JN652172NRTI, AZT, 3TCNNRTI, NVP, EFVK65RK103N, Y181C, M230LV35T, E40D, K49R, V60I, K122E, D123N, I159V, E169D, I178L, T200A, I202V, Q207E, R211K, K238R, V245K, A272S, L282C, L283I, I293VD
Pircher (2013)B1145B1145JX110243D4T, 3TC, AZTNVPM41ML, T69DN, K70KR, M184V, T215TNSYK101E, V108I, F227L, M230LV35T, V60I, K122E, D123N, E138A, D177E, I178M, T200E, I202IV, Q207K, R211A, H221Y, L228LH, V245KD
 B1132B1132JX110233D4T, 3TC, AZTNVPM184V, T215FK103KN, V106VA, M230LV35T, K49R, V60I, K122P, D123DN, I135IV, S162C, D177G, E194EK, G196E, T200A, Q207E, R211K, F227FY, L228R, K238R, P243T, V245Q, E248DD
Kityo (2017)8353383533KY062087NRTINNRTIK70E, V75M, M184V, T215IY188C, M230LV60I, A98S, V106I, V118I, D121H, K122E, R125K, I135T, I142V, D177E, T200L, Q207E, R211K, F214L, E224D, L228RD
 8356183561KY062115NRTINNRTIK65R, M184IV108I, Y181C, M230LK43N, K49R, V60I, S68G, V90I, D121Y, K122E, R125K, D177E, I178M, G196E, T200R, Q207E, R211KD
 8323283232KY061787NRTINNRTIM41L, T69D, M184V, L210W, T215YK103N, V108I, M230L, L234IK43E, S48T, K49R, V60I, D177E, I195L, Q207E, R211K, H221Y, L228HD
 2836328363KY061374NRTINNRTIM41L, T69D, M184V, L210W, T215YK103N, V108I, M230L, L234IV35T, E36D, T39R, K43E, S48T, K49R, V60I, D177E, I195L, Q207E, R211K, H221Y, L228H, V245K, D250E, A272P, L282C, L283I, R284K, I293VD
 8290982909KY061474NRTINNRTIK70R, M184V, T215F, K219QK103N, M230LK49KR, V60I, K64R, T69N, D177E, Q207E, R211K, L228RD