<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation G190S
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2006)48-41654165-30410DQ878398NRTINNRTIM41L, D67N, K70R, T215F, K219QK101E, G190SV35T, K49R, V60I, T69TN, V90I, A98S, V118I, K122E, I135T, E138A, T165I, E169D, R172RK, D177E, I178L, V179X, Q197E, E203A, Q207E, R211K, F214L, L228H, V245T, D250E, A272P, K277R, T286A, E297KR, I329L, G335D, M357MT, G359S, A376T, S379C, T386A, A400TD
Ndembi (2010)DT3479_05_P13479GQ409616AZT, 3TCNVPD67N, K70Y, F77L, M184V, T215YG190SE28K, I31L, V35T, T39I, E40D, S48P, K49R, V60I, I63L, K64N, S68N, R78K, N81I, D86E, K122E, I142V, Q151P, I159V, K173Q, D177E, T200A, Q207E, R211KD
Kouri (2012)CU25-10CU25-10JQ585358NRTINNRTIM41L, D67N, M184V, L210W, T215YK101E, Y181C, G190SE28EG, V35M, K43N, E44D, V106I, V111I, V118I, K122E, D123N, I135T, N136ND, Q174R, D177E, I178M, V189I, T200A, I202V, Q207D, H208Y, V245T, D250E, A272S, T286A, I293V, E297K, P313T, V317A, I329V, Q334DD
Reynolds (2012)C0717C0717-1JN652177AZT, 3TCEFVM184VK101E, G190SK13KN, K32R, V35I, E40D, K49KR, T58TS, V60I, D121Y, K122E, D177E, I178M, V179I, E204K, Q207E, R211K, V245Q, I257L, A272P, K277R, L282C, T286A, V292I, I293VD
Wallis (2014)4123041230KM458598NRTINNRTIV75VA, M184VK101KE, G190SV35T, E40AD, K43KE, K49R, T58S, V60I, V118VA, K122E, D123G, E138A, Q197E, T200R, Q207E, R211RKD
Kekitiinwa (2017)28229_27828229_278KY237813NRTINNRTIL74V, M184VK101E, G190SV35T, V60I, T69S, D121Y, K122E, D177E, I178M, T200M, R206K, Q207E, R211K, P243A, V245Q, D250E, A272P, L282C, L283I, T286A, I293VD
 65488_27865488_278KY237874NRTINNRTIT69GS, L74V, Y115F, M184VK101E, Y181YC, G190SV60I, D121H, K122E, I142IV, Q174QR, D177E, I178M, G196E, T200M, E204EK, R206RK, Q207E, R211KD
Kityo (2017)8292082920KY061484NRTINNRTIM41L, D67N, M184V, L210W, T215YK101E, G190SK43KQ, K49R, V60I, V90VI, V118I, K122E, I135T, D177E, I178M, T200IK, Q207E, R211KD
 8299782997KY061559NRTINNRTID67N, K70R, L74I, M184V, T215F, K219QV179E, G190SI47L, K49R, V60I, K64R, K122E, I135T, D177E, Q207E, R211K, L228HD