<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation Y188L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 3
Patients 4
Isolates 5
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK2001TK2001 D4T, 3TC, AZT, DDI, ABCEFV, NVPM41L, D67G, K70R, L74I, M184V, T215F, K219QL100I, Y188LK20R, V35T, K49KR, E53Q, V60I, T69N, D123E, I135V, K166R, D177E, T200I, Q207E, R211K, D218E, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, L283I, I293V, G316XD
  TK2001a D4T, 3TC, AZT, DDI, ABC, TDFEFV, NVPM41L, D67G, K70R, L74I, T215F, K219QL100I, Y188LK20R, V35T, E53EQ, V60I, S68SG, T69IN, D123E, I135V, Q161QH, S163X, K166R, D177E, V179VI, T200I, Q207E, R211K, D218E, L228H, Q242QH, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, L283I, A288AT, I293VD
Baxter (2006)12-22582258-30721DQ880135NRTINNRTIM41L, D67E, T69S_VG, L74V, M184VK101H, Y181CF, Y188LV60I, D121Y, K122E, T139K, D177E, I178L, V189I, T200AV, Q207E, R211K, H221Y, T240A, V245KD
 48-50525052-30515DQ878573NRTINNRTIM41L, D67N, T69D, V75M, L210W, T215YY188LP4S, K20R, V35T, T39R, K43E, E44D, V60I, K64H, L109I, V118I, I135V, T139V, S162D, K166R, K173A, D177E, Q207E, R211K, D218E, E224ED, V245Q, E248D, D250E, S251N, A272P, K277R, L283I, A288T, I293V, E297K, G333E, Q334H, G335NS, G359S, A371V, T377M, K390RD
Fokam (2011)CIRCB-8995CIRCB-8995JQ796156D4T, 3TCNVPM184VY188LV8I, K13KR, V35T, V60VI, K103KE, D121H, K122E, I135T, T139A, D177DE, I178V, Q207E, R211RK, F214L, V245DEKN, E248EK, D250E, A272P, T286A, E297K, I329V, G335ED

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