<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V179I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 7
Isolates 7
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Carr (1999)SE7108SE7108AF071473AZT, DDINoneD67N, K70R, T215Y, K219Q V35T, V60I, D121H, K122E, D123E, I135T, K173S, Q174K, D177E, I178L, V179I, T200I, Q207E, R211K, K238R, V245K, D250E, L282C, T286A, V292I, I293V, G335D, T338S, P345Q, F346Y, R356K, M357L, A360T, V365I, E370A, T377Q, S379C, K390R, A400T, E432D, V435A, A437V, V458I, H483N, L491P, K512R, S519N, Q524K, K527G, E529D, A534S, A554SD
Eshleman (2002)124661e124661eAF410212AZTNone  E6T, T7P, K11T, V35T, V60I, D123N, I142IT, D177E, I178M, V179I, T200I, Q207G, R211K, V245K, D250E, A272P, K275R, Q278QH, L279LI, L282C, T286A, I293V, S322AD
 139339y139339yAF410234AZTNone  K20R, V35T, T39KR, K49R, V60I, D121Y, K122E, I135IT, D177E, I178M, V179I, G196KR, I202IV, Q207E, R211K, V245K, D250E, A272P, K277R, T286AVD
Non-B Workgroup (2005)TK3023TK3023 AZT, 3TCNoneM184V K13R, V35T, K49R, V60I, D121Y, K122E, K173A, Q174K, D177E, I178M, V179I, I195T, Q207E, V245T, D250E, A272P, K277R, L282C, I293V, H315Q, V317MD
Ndembi (2010)DT2412_05_P12412GQ409606ABC, AZT, 3TCNoneM184V P4R, V8I, V35T, T39A, V60I, A62G, K122E, D177E, I178M, V179I, T200I, Q207E, R211KD
Fokam (2011)CIRCB-9860CIRCB-9860JQ796162AZT, 3TCNone  P4PT, K11Q, P14A, V35T, E40D, V60I, V118I, K122P, D123N, T139S, S162C, D177E, I178L, V179I, E204K, Q207E, F214L, V245T, D250E, A272P, K277R, T286AD
Inzaule (2016)1.02781.0278HM164116AZT, 3TCNoneM184V V35T, T39M, K49R, V60I, A98Q, D121Y, K122E, D123E, I135IT, K173S, Q174K, D177E, V179I, I195L, T200I, Q207E, R211K, V245I, D250E, L282C, L283I, R284K, I293V, D324ED