<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V108I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 11
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Snoeck (2004)BE40BE40AY901297AZT, DDC, D4T, 3TC, DDINVPK70R, M184VV108I, Y181CV35T, K49R, V60I, T69N, K122E, D177E, Q207E, P243T, V245K, D250ED
Non-B Workgroup (2005)UK1979UK1979AY9013703TC, D4T, AZTNVPM184VK103N, V108IV35T, V60I, D121H, K122E, I135R, D177E, E203K, Q207ED
Ndembi (2010)15845D_P115845GQ409579AZT, 3TCNVPM184VV108I, Y181C, G190GAP4T, V35T, K49R, V60I, D121Y, K122E, I135T, D177E, T200A, E204K, Q207E, R211K, F214L, H221YD
Aulicino (2011)ARN272RLDARN272RLDFJ525856NRTINNRTIM41L, D67N, T69D, K70R, L74V, M184V, L210W, T215Y, K219HA98G, K101E, V108I, Y181C, G190AS3C, K20R, E28A, V35T, T39E, E44D, V60I, V90I, L109I, K122E, I135V, I142V, S162N, I167V, V179I, T200A, E203K, Q207E, H208Y, R211KD
Charpentier (2011)CR-47CR-47FJ688253AZT, 3TCNNRTIM41L, L74I, M184V, L210W, T215YA98G, K103N, V108IK20R, V35I, T39A, E44D, V60I, V118I, K122E, I135IMT, I142T, D177E, I178L, E203EK, Q207E, H208HY, R211RK, K223KE, L228LH, V245T, D250E, A272P, K277R, T286A, V292ID
Kouri (2012)CU645-09CU645-09JQ585259NRTINNRTID67DN, M184V, L210LW, T215Y, N348NIK103N, V108I, M230MLV8I, P19PS, V35T, T39A, V60I, E79D, K122E, D123T, T139TR, I142T, E169D, D177E, I178M, T200K, E204D, Q207E, R211K, V245S, D250E, A272P, T286A, G335DD
Reynolds (2012)E0580E0580-1JN652183AZT, 3TCNVPK65KR, M184VK101KEQ, V108I, Y181CI31IL, L34LI, V35T, E40D, K49R, V60I, D121H, K122E, E169D, D177E, I178M, G196E, T200I, E204EK, Q207D, R211K, V245K, D250E, K277R, L282C, L283I, T286I, A288S, I293V, E297AD
  E0580-2JN652206AZT, 3TC, TDF, DDINVPM184VV108I, Y181CL34I, V35T, E40D, K49R, V60I, K101Q, D121H, K122E, E169D, D177E, I178L, G196E, T200I, E204K, Q207D, R211K, H221Y, V245K, D250E, T253TA, K277R, L282C, L283I, T286I, A288S, I293V, E297AD
Aghokeng (2013)HJ3116HJ3116JX982985NRTINNRTIM41L, M184V, L210W, T215FK103N, V108I, Y181CK20R, K49R, V60I, K102N, V118I, I135T, R172K, D177E, I178L, V179I, Q182S, T200A, E203D, E204K, Q207E, R211K, F214L, H221Y, L228R, V245T, A272S, L283I, T286A, I293V, E297K, R307K, V317A, I329V, Q334E, Y339W, I341V, R356K, G359S, A371V, I375V, T377I, K390R, A400T, T403MD
Pircher (2013)B1145B1145JX110243D4T, 3TC, AZTNVPM41ML, T69DN, K70KR, M184V, T215TNSYK101E, V108I, F227L, M230LV35T, V60I, K122E, D123N, E138A, D177E, I178M, T200E, I202IV, Q207K, R211A, H221Y, L228LH, V245KD
Sigaloff (2013)JCR047_0JCR047_0JX181988NRTINNRTID67G, T69D, K70R, M184V, K219HA98G, V108I, Y181CV35T, K43E, K49R, V60I, I94L, K122E, I135M, S163SC, T165L, R172K, D177E, I178M, T200I, E203R, E204K, Q207E, R211K, E224K, V245K, D250E, A272P, Q278H, L282C, L283I, T286A, A288TD
Theys (2013)131238131238 D4T, 3TCEFVM184VK103N, V108IE6A, K11Q, K20R, V35T, V60I, D121Y, K122E, I135V, I142T, T165I, E169D, D177E, I178L, G196E, T200A, E204K, Q207E, R211K, F214L, P243T, V245T, D250E, A272P, K281R, T286TA, E297K, I329L, G333D, Q334RD