<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V106I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2001)SE765SE765AF388124NoneNVP  V35T, K49R, V60I, V106I, D121Y, K122E, D123DG, I135T, N137S, T165I, D177E, I178IM, T200I, Q207E, R211K, V245K, E248ED, D250E, A272P, K277R, L282C, L283I, T286A, I293VD
Hawkins (2009)Q234ZZQ234FJ931225D4T, 3TCNVPT69D V35T, E40A, K43E, K49R, V60I, V106I, V118I, K122KE, T139S, T165I, N175H, D177E, I178L, Q197E, E203D, E204R, Q207D, R211K, F214L, E224D, V245T, E248Q, A272P, K275R, K277KR, V292I, I293V, I329V, Q334ED
 Q943ZZQ943FJ931287D4T, 3TCNVPD67N, K70R, M184V, K219QY188CV35T, T39TA, K49R, V106I, K122E, D123N, I135T, S162N, K173R, Q174R, D177E, I178M, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, T286A, E297Q, D324E, I329VD
Burda (2010)07BDHS4007BDHS40GQ344972D4T, 3TCNVPM184V, N348IY181CV35T, T39A, E40D, K49R, V60I, V106I, I135T, S162C, R172K, N175H, D177E, I178L, Q197R, T200E, K201I, E204K, Q207E, F214L, H221Y, V245K, A272P, T286A, I293V, E297K, Q334E, G335S, T338S, Y339W, R356K, K374Q, T377R, K390R, A400T, T403M, V435ID
Sigaloff (2011)HIV100832HIV100832JN132249TDF, FTCEFVA62V, K65R, M184VY188CK20R, V35I, S68G, V106I, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, V245H, D250E, A272P, K277R, L282C, T286A, A288TD
 HIV102963HIV102963JN132328D4T, 3TCNVPM41L, K65N, M184V, T215YK103NE28A, V35T, I47V, V60I, K64*, K66R, L74*, R83I, Q91H, V106I, K122E, D123N, I135T, E138Q, D177E, T200I, Q207EK, R211K, V245Q, D250E, A272P, K277R, L282C, L283I, T286A, I293VD
Kouri (2012)CU25-10CU25-10JQ585358NRTINNRTIM41L, D67N, M184V, L210W, T215YK101E, Y181C, G190SE28EG, V35M, K43N, E44D, V106I, V111I, V118I, K122E, D123N, I135T, N136ND, Q174R, D177E, I178M, V189I, T200A, I202V, Q207D, H208Y, V245T, D250E, A272S, T286A, I293V, E297K, P313T, V317A, I329V, Q334DD
 CU1270-09CU1270-09JQ585285NRTINNRTID67N, K70R, K219QY181C, G190GAV8VAIT, K20R, V35T, T39A, E40D, K49R, V60I, T69TN, K101KQ, V106I, K122E, I135R, E169D, D177E, T200TA, I202V, Q207E, R211K, F214L, H221Y, V245Q, D250E, A272P, T286A, K311R, I329V, G335DD
Kityo (2017)8353383533KY062087NRTINNRTIK70E, V75M, M184V, T215IY188C, M230LV60I, A98S, V106I, V118I, D121H, K122E, R125K, I135T, I142V, D177E, T200L, Q207E, R211K, F214L, E224D, L228RD
 8291882918KY061482NRTINNRTID67N, K70R, M184V, K219QV179E, Y188LK49R, V60I, K64NY, T69TN, V106I, D121Y, K122E, P133PL, P170PL, D177E, T200R, E203K, Q207E, R211K, L228HD
 8330483304KY061859NRTINNRTIM41L, D67N, T69D, V75M, M184V, L210W, T215YK101E, V108I, G190AE44D, K49R, V60I, V106I, V118I, D121Y, K122E, D177E, V179I, V189I, Q207E, R211KD
 8354683546KY062100NRTINNRTIK65R, M184VY181C, G190AK49R, E53ED, V60I, S68N, V106I, D121Y, K122E, S162D, Q174K, D177E, I178L, V179I, T200M, Q207E, R211KD
Rhee (2017)EC009877EC009877KY190986TDF, FTCNVPM184MIVK103KN, Y181CV35T, T39*AES, K49KR, V60I, S68G, V106I, I135T, I142IT, K166R, R172K, D177E, I178L, Q197QE, T200TS, E204K, Q207E, R211RK, F214LD
 17141714_FL TDF, 3TCEFVK70E, M184VY188LV35I, K49R, V60I, V90VI, V106I, D121Y, K122E, I135IT, S162A, D177E, I178M, V179I, T200I, Q207E, R211K, V245K, D250E, S251N, A272P, K281R, T286A, E291D, I293IV, P294T, E297K, K311RD